Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development

Neuron

Volumn 94, Issue 2, 2017, Pages 322-336.e5

  Thomas Jinu, Swapna ^a   Gordon, Patricia M ^a   Fielding, Triona ^a   Taylor, Richard ^a   Smith, Bradley N ^b   Snowden, Victoria ^a   Blanc, Eric ^a   Vance, Caroline ^b   Topp, Simon ^b   Wong, Chun Hao ^b   Bielen, Holger ^a   Williams, Katherine L ^d   McCann, Emily P ^d   Nicholson, Garth A ^d,e   Pan Vazquez, Alejandro ^a   Fox, Archa H ^f,g   Bond, Charles S ^f   Talbot, William S ^c   Blair, Ian P ^d   Shaw, Christopher E ^b   Houart, Corinne ^a   more..

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MACQUARIE UNIVERSITY   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

^f UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^g PATHWEST LABORATORY MEDICINE   (Australia)

Author keywords

amyotrophic lateral sclerosis; axonogenesis; central nervous system; motor neurons; neurodegeneration; neurodevelopment; PSF; RNA processing; RNA binding protein; SFPQ

Indexed keywords

MEMBRANE PROTEIN; PROTEIN SFPQ; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; MESSENGER RNA; PTB ASSOCIATED SPLICING FACTOR; RNA BINDING PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AXON; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CELL GROWTH; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; INTRON; MOTONEURON; MOTOR DEVELOPMENT; MOTOR PERFORMANCE; NERVE CELL; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; ZEBRA FISH; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOTOR CORTEX; MOUSE; RNA SPLICING;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONS; DNA-BINDING PROTEINS; HUMANS; MICE; MOTOR CORTEX; MOTOR NEURONS; PTB-ASSOCIATED SPLICING FACTOR; RNA SPLICING; RNA, MESSENGER; RNA-BINDING PROTEINS; ZEBRAFISH;

EID: 85017187298     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.03.026     Document Type: Article

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