Dual-utility NLS drives RNF169-dependent DNA damage responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 14, 2017, Pages e2872-e2881

  An, Liwei ^a   Jiang, Yiyang ^b   Ng, Howin H W ^a   Man, Ellen P S ^c   Chen, Jie ^a   Khoo, Ui Soon ^c   Gong, Qingguo ^b   Huen, Michael S Y ^a,d  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c Department of Pathology ^*  (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Rnf169|dna damage|dna repair|deubiquitylation; USP7

Indexed keywords

CYCLOHEXIMIDE; DEUBIQUITINASE; HYDROGEN; MALTOSE BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; RNF169 PROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; UNCLASSIFIED DRUG; USP7 PROTEIN; RNF169 PROTEIN, HUMAN; UBIQUITIN CARBOXYL TERMINAL HYDROLASE 7; UBIQUITIN PROTEIN LIGASE; USP7 PROTEIN, HUMAN;

ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DELETION MUTANT; DNA DAMAGE RESPONSE; DOWN REGULATION; FEMALE; GENE CONVERSION; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROGEN BOND; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; ISOTHERMAL TITRATION CALORIMETRY; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; STABLE EXPRESSION; TURNOVER TIME; UBIQUITINATION; WESTERN BLOTTING; ADULT; AGED; BREAST TUMOR; CELL LINE; CHEMISTRY; DNA DAMAGE; DNA REPAIR; GENETICS; METABOLISM; MIDDLE AGED; MORTALITY; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN DOMAIN; VERY ELDERLY; X RAY CRYSTALLOGRAPHY;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CELL LINE; CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA REPAIR; FEMALE; HUMANS; MIDDLE AGED; NUCLEAR LOCALIZATION SIGNALS; PROTEIN CONFORMATION; PROTEIN DOMAINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITIN-SPECIFIC PEPTIDASE 7; UBIQUITINATION;

EID: 85017004114     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1616602114     Document Type: Article

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