ATM-dependent phosphorylation of the fanconi anemia protein PALB2 promotes the DNA damage response

Journal of Biological Chemistry

Volumn 290, Issue 46, 2015, Pages 27545-27556

  Guo, Yingying ^a   Feng, Wanjuan ^a   Sy, Shirley M H ^a,b   Huen, Michael S Y ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; IONIZING RADIATION; PROTEINS; TUMORS;

ATAXIA-TELANGIECTASIA MUTATED; CELLULAR RESPONSE; DNA DAMAGE RESPONSE; HYPERPHOSPHORYLATED; PHOSPHORYLATION ANALYSIS; REGULATORY MECHANISM; SUSTAINED ACTIVATION; TUMOR SUPPRESSOR PROTEINS;

PHOSPHORYLATION;

ATM PROTEIN; ATR PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; FANCONI ANEMIA PROTEIN; PALB2 PROTEIN; SERINE; UNCLASSIFIED DRUG; ATM PROTEIN, HUMAN; BRCA1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PALB2 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CANCER INHIBITION; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE INTERACTION; GENETIC STABILITY; GENOTOXICITY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TUMOR SUPPRESSOR GENE; FEMALE; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ATAXIA TELANGIECTASIA MUTATED PROTEINS; BRCA1 PROTEIN; DNA DAMAGE; DNA REPAIR; FEMALE; HEK293 CELLS; HELA CELLS; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION; RADIATION, IONIZING; SERINE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84946919323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.672626     Document Type: Article

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