-
1
-
-
0033783007
-
Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae
-
Amerik AY, Li S, Hochstrasser M. (2000). Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae. Biol Chem 381: 981-992.
-
(2000)
Biol Chem
, vol.381
, pp. 981-992
-
-
Amerik, A.Y.1
Li, S.2
Hochstrasser, M.3
-
2
-
-
0037415605
-
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation
-
Babu JR, Jeganathan KB, Baker DJ, Wu X, Kang-Decker N, van Deursen JM. (2003). Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. J Cell Biol 3: 341-353.
-
(2003)
J Cell Biol
, vol.3
, pp. 341-353
-
-
Babu, J.R.1
Jeganathan, K.B.2
Baker, D.J.3
Wu, X.4
Kang-Decker, N.5
Van Deursen, J.M.6
-
3
-
-
44349179787
-
A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model
-
Becker K, Marchenko ND, Palacios G, Moll UM. (2008). A role of HAUSP in tumor suppression in a human colon carcinoma xenograft model. Cell Cycle 7: 1205-1213.
-
(2008)
Cell Cycle
, vol.7
, pp. 1205-1213
-
-
Becker, K.1
Marchenko, N.D.2
Palacios, G.3
Moll, U.M.4
-
4
-
-
21244451434
-
ARF-BP1/ Mule is a critical mediator of the ARF tumor suppressor
-
Chen D, Kon N, Li M, Zhang W, Qin J, Gu W. (2005). ARF-BP1/ Mule is a critical mediator of the ARF tumor suppressor. Cell 121: 1071-1083.
-
(2005)
Cell
, vol.121
, pp. 1071-1083
-
-
Chen, D.1
Kon, N.2
Li, M.3
Zhang, W.4
Qin, J.5
Gu, W.6
-
5
-
-
0029802591
-
P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen X, Ko LJ, Jayaraman L, Prives C. (1996). p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev 1: 2438-2451.
-
(1996)
Genes Dev
, vol.1
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
6
-
-
1842431904
-
Tumour suppression: Disruption of HAUSP gene stabilizes p53
-
Cummins JM, Rago C, Kohli M, Kinzler KW, Lengauer C, Vogelstein B. (2004). Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature 428: 1.
-
(2004)
Nature
, vol.428
, pp. 1
-
-
Cummins, J.M.1
Rago, C.2
Kohli, M.3
Kinzler, K.W.4
Lengauer, C.5
Vogelstein, B.6
-
7
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
Dornan D, Wertz I, Shimizu H, Arnott D, Frantz GD, Dowd P, et al. (2004). The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429: 86-92.
-
(2004)
Nature
, vol.429
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
Arnott, D.4
Frantz, G.D.5
Dowd, P.6
-
8
-
-
0032889557
-
The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its roles in the activation of gene expression and stimulation of virus replication
-
Everett RD, Meredith M, Orr A. (1999). The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its roles in the activation of gene expression and stimulation of virus replication. J Virol 73: 417-426.
-
(1999)
J Virol
, vol.73
, pp. 417-426
-
-
Everett, R.D.1
Meredith, M.2
Orr, A.3
-
10
-
-
0348111469
-
Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP
-
Holowaty MN, Sheng Y, Nguyen T, Arrowsmith C, Frappier L. (2003). Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP. J Biol Chem 278: 47753-47761.
-
(2003)
J Biol Chem
, vol.278
, pp. 47753-47761
-
-
Holowaty, M.N.1
Sheng, Y.2
Nguyen, T.3
Arrowsmith, C.4
Frappier, L.5
-
11
-
-
0036311587
-
USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product
-
Hong S, Kim SJ, Ka S, Choi I, Kang S. (2002). USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product. Mol Cell Neurosci 20: 298-306.
-
(2002)
Mol Cell Neurosci
, vol.20
, pp. 298-306
-
-
Hong, S.1
Kim, S.J.2
Ka, S.3
Choi, I.4
Kang, S.5
-
12
-
-
0037184947
-
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
-
Hu M, Li P, Li M, Li W, Yao T, Wu JW, et al. (2002). Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell 111: 1041-1054.
-
(2002)
Cell
, vol.111
, pp. 1041-1054
-
-
Hu, M.1
Li, P.2
Li, M.3
Li, W.4
Yao, T.5
Wu, J.W.6
-
13
-
-
33244490784
-
Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: Implications for the regulation of the p53-MDM2 pathway
-
Hu M, Gu L, Li M, Jeffrey PD, Gu W, Shi Y. (2006). Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway. PLoS Biol 4: e27.
-
(2006)
PLoS Biol
, vol.4
-
-
Hu, M.1
Gu, L.2
Li, M.3
Jeffrey, P.D.4
Gu, W.5
Shi, Y.6
-
14
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones SN, Roe AE, Donehower LA, Bradley A. (1995). Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 378: 206-208.
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
15
-
-
0033553532
-
Substrate targeting in the ubiquitin system
-
Laney JD, Hochstrasser M. (1999). Substrate targeting in the ubiquitin system. Cell 14: 427-430.
-
(1999)
Cell
, vol.14
, pp. 427-430
-
-
Laney, J.D.1
Hochstrasser, M.2
-
16
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng RP, Lin Y, Ma W, Wu H, Lemmers B, Chung S, et al. (2003). Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 112: 779-791.
-
(2003)
Cell
, vol.112
, pp. 779-791
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
Wu, H.4
Lemmers, B.5
Chung, S.6
-
17
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
18
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, et al. (2002). Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416: 648-653.
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
-
19
-
-
1842421376
-
A dynamic role of HAUSP in the p53-Mdm2 pathway
-
Li M, Brooks CL, Kon N, Gu W. (2004). A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell 13: 879-886.
-
(2004)
Mol Cell
, vol.13
, pp. 879-886
-
-
Li, M.1
Brooks, C.L.2
Kon, N.3
Gu, W.4
-
20
-
-
19444367393
-
Loss of HAUSP-mediated deubiquitina-tion contributes to DNA damage-induced destabilization of Hdmx and Hdm2
-
Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, et al. (2005). Loss of HAUSP-mediated deubiquitina-tion contributes to DNA damage-induced destabilization of Hdmx and Hdm2. Mol Cell 18: 565-576.
-
(2005)
Mol Cell
, vol.18
, pp. 565-576
-
-
Meulmeester, E.1
Maurice, M.M.2
Boutell, C.3
Teunisse, A.F.4
Ovaa, H.5
Abraham, T.E.6
-
21
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna R, Wagner DS, Lozano G. (1995). Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378: 203-206.
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
22
-
-
11144354828
-
P53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma
-
Mori S, Ito G, Usami N, Yoshioka H, Ueda Y, Kodama Y, et al. (2004). p53 apoptotic pathway molecules are frequently and simultaneously altered in nonsmall cell lung carcinoma. Cancer 100: 1673-1682.
-
(2004)
Cancer
, vol.100
, pp. 1673-1682
-
-
Mori, S.1
Ito, G.2
Usami, N.3
Yoshioka, H.4
Ueda, Y.5
Kodama, Y.6
-
23
-
-
34347346071
-
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo
-
Niendorf S, Oksche A, Kisser A, Lohler J, Prinz M, Schorle H, et al. (2007). Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol 27: 5029-5039.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5029-5039
-
-
Niendorf, S.1
Oksche, A.2
Kisser, A.3
Lohler, J.4
Prinz, M.5
Schorle, H.6
-
24
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, Sixma TK, et al. (2005). A genomic and functional inventory of deubiquitinating enzymes. Cell 123: 773-786.
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
Sixma, T.K.6
-
25
-
-
9744227183
-
Ubiquitin: Structures, functions, mechanisms
-
Pickart CM, Eddins MJ. (2004). Ubiquitin: structures, functions, mechanisms. Biochim Biophys Acta 29: 55-72.
-
(2004)
Biochim Biophys Acta
, vol.29
, pp. 55-72
-
-
Pickart, C.M.1
Eddins, M.J.2
-
27
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW. (2009). Defining the human deubiquitinating enzyme interaction landscape. Cell 23: 389-403.
-
(2009)
Cell
, vol.23
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
28
-
-
33746648187
-
Critical role for Daxx in regulating Mdm2
-
Tang J, Qu LK, Zhang J, Wang W, Michaelson JS, Degenhardt YY, et al. (2006). Critical role for Daxx in regulating Mdm2. Nat Cell Biol 8: 855-862.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 855-862
-
-
Tang, J.1
Qu, L.K.2
Zhang, J.3
Wang, W.4
Michaelson, J.S.5
Degenhardt, Y.Y.6
-
29
-
-
33749188883
-
FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP
-
van der Horst A, de Vries-Smits AM, Brenkman AB, van Triest MH, van den Broek N, Colland F, et al. (2006). FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP. Nat Cell Biol 8: 1064-1073.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1064-1073
-
-
Van Der Horst, A.1
De Vries-Smits, A.M.2
Brenkman, A.B.3
Van Triest, M.H.4
Van Den Broek, N.5
Colland, F.6
-
30
-
-
14644406268
-
GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7
-
van der Knaap JA, Kumar BR, Moshkin YM, Langenberg K, Krijgsveld J, Heck AJ, et al. (2005). GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. Mol Cell 17: 695-707.
-
(2005)
Mol Cell
, vol.17
, pp. 695-707
-
-
Van Der Knaap, J.A.1
Kumar, B.R.2
Moshkin, Y.M.3
Langenberg, K.4
Krijgsveld, J.5
Heck, A.J.6
-
31
-
-
0035853083
-
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function
-
Wu X, Kasper LH, Mantcheva RT, Mantchev GT, Springett MJ, van Deursen JM. (2001). Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function. Proc Natl Acad Sci USA 13: 3191-3196.
-
(2001)
Proc Natl Acad Sci USA
, vol.13
, pp. 3191-3196
-
-
Wu, X.1
Kasper, L.H.2
Mantcheva, R.T.3
Mantchev, G.T.4
Springett, M.J.5
Van Deursen, J.M.6
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