Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis

Journal of Clinical Investigation

Volumn 126, Issue 6, 2016, Pages 2205-2220

  Wang, Qian ^a   Ma, Shuai ^a   Song, Nan ^a   Li, Xin ^a   Liu, Ling ^a   Yang, Shangda ^a   Ding, Xiang ^b   Shan, Lin ^a   Zhou, Xing ^a   Su, Dongxue ^a   Wang, Yue ^a   Zhang, Qi ^a   Liu, Xinhua ^a   Yu, Na ^a   Zhang, Kai ^a   Shang, Yongfeng ^a,c   Yao, Zhi ^a   Shi, Lei ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOM SYNDROME HELICASE; CYCLIN A2; DEUBIQUITINASE; DEUBIQUITINASE USP7; DNA; DOUBLE STRANDED DNA; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE PHF8; KU ANTIGEN; UNCLASSIFIED DRUG; CCNA2 PROTEIN, HUMAN; PHF8 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UBIQUITIN THIOLESTERASE; USP7 PROTEIN, HUMAN;

ARTICLE; BREAST CARCINOMA; CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DEUBIQUITINATION; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; FEMALE; GENOTOXICITY; HELA CELL LINE; HISTONE MODIFICATION; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; UPREGULATION; BREAST NEOPLASMS; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; GENETIC EPIGENESIS; GENETICS; MCF-7 CELL LINE; METABOLISM; PROTEIN DOMAIN;

BREAST NEOPLASMS; CARCINOGENESIS; CYCLIN A2; DNA DAMAGE; DNA REPAIR; ENZYME STABILITY; EPIGENESIS, GENETIC; FEMALE; HISTONE DEMETHYLASES; HUMANS; MCF-7 CELLS; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; UBIQUITIN THIOLESTERASE; UP-REGULATION;

EID: 84974577750     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI85747     Document Type: Article

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