Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 14, 2017, Pages E2920-E2928

  Mao, Dainan ^a   Bushin, Leah B ^a   Moon, Kyuho ^a   Wu, Yihan ^a   Seyedsayamdost, Mohammad R ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

Biosynthetic gene clusters; Burkholderia thailandensis; Natural products; Regulation; Virulence

Indexed keywords

ADENOSINE TRIPHOSPHATE; MALLEILACTONE; REGULATOR PROTEIN; SCMR PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIAL PROTEIN; LACTONE;

ARTICLE; BACTERIAL GENETICS; BACTERIAL METABOLISM; BACTERIAL VIRULENCE; BIOFILM; BURKHOLDERIA THAILANDENSIS; CAENORHABDITIS ELEGANS; CHEMICAL ANALYSIS; CONTROLLED STUDY; DELETION MUTANT; DOWN REGULATION; GENE REPRESSION; IN VITRO STUDY; IN VIVO STUDY; METABOLOMICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUORUM SENSING; SECONDARY METABOLISM; SILENT GENE; STRESS; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; WILD TYPE; ANIMAL; BURKHOLDERIA; BURKHOLDERIA INFECTION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIOLOGY; MULTIGENE FAMILY; PATHOGENICITY; REGULATOR GENE; VIRULENCE;

ANIMALS; BACTERIAL PROTEINS; BIOFILMS; BURKHOLDERIA; BURKHOLDERIA INFECTIONS; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION, BACTERIAL; GENES, REGULATOR; LACTONES; MULTIGENE FAMILY; SECONDARY METABOLISM; VIRULENCE;

EID: 85016936216     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1619529114     Document Type: Article

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