Chicoric acid ameliorates lipopolysaccharide-induced oxidative stress via promoting the keap1/Nrf2 transcriptional signaling pathway in BV-2 microglial cells and mouse brain

Journal of Agricultural and Food Chemistry

Volumn 65, Issue 2, 2017, Pages 338-347

  Liu, Qian ^a   Hu, Yaya ^a   Cao, Youfang ^a   Song, Ge ^a   Liu, Zhigang ^a   Liu, Xuebo ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Chicoric acid; Keap1 Nrf2; Lipopolysaccharide; Microglia; Oxidative stress

Indexed keywords

ANTIOXIDANTS; ENZYMES; MAMMALS; OXIDATIVE STRESS; PLANTS (BOTANY);

CHICORIC ACIDS; KEAP1/NRF2; LIPOPOLYSACCHARIDES; MICROGLIA; MITOCHONDRIAL DYSFUNCTION; MOLECULAR MODELING STUDIES; NUTRACEUTICAL COMPONENTS; TRANSCRIPTIONAL SIGNALING;

CELL SIGNALING;

ANTIOXIDANT; CAFFEIC ACID DERIVATIVE; CICHORIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KEAP1 PROTEIN, MOUSE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LIPOPOLYSACCHARIDE; NFE2L2 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; SUCCINIC ACID DERIVATIVE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; METABOLISM; MICROGLIA; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; BRAIN; CAFFEIC ACIDS; CELLS, CULTURED; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LIPOPOLYSACCHARIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED C57BL; MICROGLIA; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUCCINATES;

EID: 85016637607     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.6b04873     Document Type: Article

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