Chicory, a typical vegetable in Mediterranean diet, exerts a therapeutic role in established atherosclerosis in apolipoprotein E-deficient mice

Molecular Nutrition and Food Research

Volumn 59, Issue 9, 2015, Pages 1803-1813

  Lin, Weiqun ^a   Liu, Chaoqun ^a   Yang, Hai ^a   Wang, Wenting ^a   Ling, Wenhua ^a   Wang, Dongliang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Atherosclerosis; Chicory; Macrophage; Mediterranean diet; Phenolic acid

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; ABCA1 PROTEIN, MOUSE; ABCG1 PROTEIN, MOUSE; APOLIPOPROTEIN E; CCL2 PROTEIN, MOUSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TRIACYLGLYCEROL; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; ATHEROSCLEROSIS; BLOOD; CHEMISTRY; CHICORY; DEFICIENCY; DIET THERAPY; FOAM CELL; FREEZE DRYING; GENE SILENCING; GENETICS; HOMEOSTASIS; KNOCKOUT MOUSE; MALE; MEDITERRANEAN DIET; METABOLISM; MOUSE; OXIDATIVE STRESS; PERITONEUM MACROPHAGE; VEGETABLE;

ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; ATP BINDING CASSETTE TRANSPORTER 1; ATP-BINDING CASSETTE TRANSPORTERS; CHEMOKINE CCL2; CHICORY; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIET, MEDITERRANEAN; FOAM CELLS; FREEZE DRYING; GENE SILENCING; HOMEOSTASIS; INTERCELLULAR ADHESION MOLECULE-1; LIPOPROTEINS; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDES; TRIGLYCERIDES; VASCULAR CELL ADHESION MOLECULE-1; VEGETABLES;

EID: 84942834924     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201400925     Document Type: Article

References (31)

1. Moore, K. J., Sheedy, F. J., Fisher, E. A., Macrophages in atherosclerosis: a dynamic balance. Nat. Rev. Immunol. 2013, 13, 709-721.
2. Sofi, F., Abbate, R., Gensini, G. F., Casini, A., Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am. J. Clin. Nutr. 2010, 92, 1189-1196.
3. Trichopoulou, A., Martinez-Gonzalez, M. A., Tong, T. Y., Forouhi, N. G. et al., Definitions and potential health benefits of the Mediterranean diet: views from experts around the world. BMC Med. 2014, 12, 112.
4. Estruch, R., Ros, E., Salas-Salvado, J., Covas, M. I. et al., Primary prevention of cardiovascular disease with a Mediterranean diet. N. Engl. J. Med. 2013, 368, 1279-1290.
5. Rossetto, M., Lante, A., Vanzani, P., Spettoli, P. et al., Red chicories as potent scavengers of highly reactive radicals: a study on their phenolic composition and peroxyl radical trapping capacity and efficiency. J. Agric. Food Chem. 2005, 53, 8169-8175.
6. Street, R. A., Sidana, J., Prinsloo, G., Cichorium intybus: traditional uses, phytochemistry, pharmacology, and toxicology. Evid. Based Complement. Alternat. Med. 2013, 2013, 579319.
7. Khadem, S., Marles, R. J., Monocyclic phenolic acids; hydroxy- and polyhydroxybenzoic acids: occurrence and recent bioactivity studies. Molecules 2010, 15, 7985-8005.
8. Scazzocchio, B., Vari, R., Filesi, C., D'Archivio, M. et al., Cyanidin-3-O-beta-glucoside and protocatechuic acid exert insulin-like effects by upregulating PPARgamma activity in human omental adipocytes. Diabetes 2011, 60, 2234-2244.
9. Wu, C., Luan, H., Zhang, X., Wang, S. et al., Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages. PLoS One 2014, 9, e95452.
10. van Dijk, A. E., Olthof, M. R., Meeuse, J. C., Seebus, E. et al., Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. Diabetes Care 2009, 32, 1023-1025.
11. Natella, F., Nardini, M., Belelli, F., Scaccini, C., Coffee drinking induces incorporation of phenolic acids into LDL and increases the resistance of LDL to ex vivo oxidation in humans. Am. J. Clin. Nutr. 2007, 86, 604-609.
12. Wang, D., Wei, X., Yan, X., Jin, T., Ling, W., Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice. J. Agric. Food Chem. 2010, 58, 12722-12728.
13. Wang, D., Zou, T., Yang, Y., Yan, X., Ling, W., Cyanidin-3-O-beta-glucoside with the aid of its metabolite protocatechuic acid, reduces monocyte infiltration in apolipoprotein E-deficient mice. Biochem. Pharmacol. 2011, 82, 713-719.
14. Wang, D., Xia, M., Yan, X., Li, D. et al., Gut microbiota metabolism of anthocyanin promotes reverse cholesterol transport in mice via repressing miRNA-10b. Circ. Res. 2012, 111, 967-981.
15. Xia, X., Ling, W., Ma, J., Xia, M. et al., An anthocyanin-rich extract from black rice enhances atherosclerotic plaque stabilization in apolipoprotein E-deficient mice. J. Nutr. 2006, 136, 2220-2225.
16. Wang, D., Yan, X., Xia, M., Yang, Y. et al., Coenzyme Q10 promotes macrophage cholesterol efflux by regulation of the activator protein-1/miR-378/ATP-binding cassette transporter G1-signaling pathway. Arterioscler. Thromb. Vasc. Biol. 2014, 34, 1860-1870.
17. Xia, M., Hou, M., Zhu, H., Ma, J. et al., Anthocyanins induce cholesterol efflux from mouse peritoneal macrophages the role of the peroxisome proliferator-activated receptor γ-liver X receptor α-ABCA1 pathway. J. Biol. Chem. 2005, 280, 36792-36801.
18. Abid, M. R., Spokes, K. C., Shih, S. C., Aird, W. C., NADPH oxidase activity selectively modulates vascular endothelial growth factor signaling pathways. J. Biol. Chem. 2007, 282, 35373-35385.
19. Randolph, G. J., Mechanisms that regulate macrophage burden in atherosclerosis. Circ. Res. 2014, 114, 1757-1771.
20. Drummond, G. R., Selemidis, S., Griendling, K. K., Sobey, C. G., Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat. Rev. Drug Discov. 2011, 10, 453-471.
21. Yvan-Charvet, L., Welch, C., Pagler, T. A., Ranalletta, M. et al., Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. Circulation 2008, 118, 1837-1847.
22. Yvan-Charvet, L., Pagler, T. A., Seimon, T. A., Thorp, E. et al., ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis. Circ. Res. 2010, 106, 1861-1869.
23. Sofi, F., Vecchio, S., Giuliani, G., Martinelli, F. et al., Dietary habits, lifestyle and cardiovascular risk factors in a clinically healthy Italian population: the Florence diet is not Mediterranean. Eur. J. Clin. Nutr. 2005, 59, 584-591.
24. Ferro-Luzzi, A., James, W. P., Kafatos, A., The high-fat Greek diet: a recipe for all? Eur. J. Clin. Nutr. 2002, 56, 796-809.
25. Woo, K. S., Chook, P., Raitakari, O. T., McQuillan, B. et al., Westernization of Chinese adults and increased subclinical atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 1999, 19, 2487-2493.
26. Westerterp, M., Murphy, A. J., Wang, M., Pagler, T. A. et al., Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice. Circ. Res. 2013, 112, 1456-1465.
27. Rader, D. J., Molecular regulation of HDL metabolism and function: implications for novel therapies. J. Clin. Invest. 2006, 116, 3090-3100.
28. Yvan-Charvet, L., Ranalletta, M., Wang, N., Han, S. et al., Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. J. Clin. Invest. 2007, 117, 3900-3908.
29. Uto-Kondo, H., Ayaori, M., Ogura, M., Nakaya, K. et al., Coffee consumption enhances high-density lipoprotein-mediated cholesterol efflux in macrophages. Circ. Res. 2010, 106, 779-787.
30. Xie, C., Kang, J., Chen, J. R., Nagarajan, S. et al., Phenolic acids are in vivo atheroprotective compounds appearing in the serum of rats after blueberry consumption. J. Agric. Food Chem. 2011, 59, 10381-10387.
31. Abd El-Mageed, N. M., Hepatoprotective effect of feeding celery leaves mixed with chicory leaves and barley grains to hypercholesterolemic rats. Pharmacogn. Mag. 2011, 7, 151-156.