Disruption of Circulating Extracellular Vesicles as a Novel Therapeutic Strategy against Cancer Metastasis

Molecular Therapy

Volumn 25, Issue 1, 2017, Pages 181-191

  Nishida Aoki, Nao ^a   Tominaga, Naoomi ^a   Takeshita, Fumitaka ^a   Sonoda, Hikaru ^a,b   Yoshioka, Yusuke ^a   Ochiya, Takahiro ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b Theoria Science Inc   (Japan)

Author keywords

breast cancer; CD63; CD9; exosome; extracellular vesicles; metastasis; therapeutic antibody

Indexed keywords

CD3 ANTIBODY; CD9 ANTIBODY; CELL ANTIBODY; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CD63 ANTIGEN; CD9 ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; EXOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LUNG METASTASIS; LYMPH NODE METASTASIS; MACROPHAGE; METASTASIS; METASTASIS INHIBITION; MOLECULARLY TARGETED THERAPY; MOUSE; MOUSE MODEL; NONHUMAN; PRIMARY TUMOR; THORACIC CAVITY METASTASIS; TREATMENT OUTCOME; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR XENOGRAFT; ANIMAL; CELL MOTION; CELL PROLIFERATION; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; IMMUNOLOGY; MEMBRANE MICROPARTICLE; METABOLISM; NEOPLASM; PATHOLOGY; PHAGOCYTOSIS; TUMOR VOLUME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CELL MOVEMENT; CELL PROLIFERATION; CELL-DERIVED MICROPARTICLES; DISEASE MODELS, ANIMAL; EXTRACELLULAR VESICLES; HUMANS; MACROPHAGES; MICE; NEOPLASM METASTASIS; NEOPLASMS; PHAGOCYTOSIS; TETRASPANIN 30; TETRASPANIN-29; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85016274293     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1016/j.ymthe.2016.10.009     Document Type: Article

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