Environmental stressors and cardio-metabolic disease: Part II-mechanistic insights

European Heart Journal

Volumn 38, Issue 8, 2017, Pages 557-564

  Münzel, Thomas ^a   Sørensen, Mette ^b   Gori, Tommaso ^a   Schmidt, Frank P ^a   Rao, Xiaoquan ^c   Brook, Frank R ^d   Chen, Lung Chi ^e   Brook, Robert D ^f   Rajagopalan, Sanjay ^c  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^c UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^d ENVIRONMENT CANADA   (Canada)

^e NEW YORK UNIVERSITY   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Air pollution; Atherosclerosis; Cardiometabolic disease; Cardiovascular risk factor; Environment; Inflammation; Noise; Oxidative stress

Indexed keywords

AIR POLLUTION; AUTONOMIC NEUROPATHY; CARDIOMETABOLIC DISEASE; CARDIOMETABOLIC RISK; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DIABETES MELLITUS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; ENVIRONMENTAL IMPACT; ENVIRONMENTAL STRESS; EVIDENCE BASED PRACTICE; GLOBAL DISEASE BURDEN; HEART DISEASE; HUMAN; HYPERTENSION; INFLAMMATION; KNOWLEDGE; META ANALYSIS (TOPIC); METABOLIC DISORDER; NOISE POLLUTION; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW (TOPIC); VASCULAR DISEASE; ANIMAL; DISEASE MODEL; PARTICULATE MATTER; RISK FACTOR; TRAFFIC NOISE;

AIR POLLUTION; ANIMALS; CARDIOVASCULAR DISEASES; DISEASE MODELS, ANIMAL; ENVIRONMENTAL EXPOSURE; HUMANS; METABOLIC DISEASES; NOISE, TRANSPORTATION; PARTICULATE MATTER; RISK FACTORS;

EID: 85016261401     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehw294     Document Type: Review

References (70)

1. Stansfeld SA. Noise effects on health in the context of air pollution exposure. Int J Environ Res Public Health 2015;12:12735-12760.
2. Griefahn B, Marks A, Robens S. Noise emitted from road, rail and air traffic and their effects on sleep. J Sound Vib 2006;295:129-140.
3. Basner M, Isermann U, Samel A. Aircraft noise effects on sleep: application of the results of a large polysomnographic field study. J Acoust Soc Am 2006;119: 2772-2784.
4. Griefahn B, Brode P, Marks A, Basner M. Autonomic arousals related to traffic noise during sleep. Sleep 2008;31:569-577.
5. Marks A, Griefahn B, Basner M. Event-related awakenings caused by nocturnal transportation noise. Noise Contrib Eng J 2008;56:52-62.
6. Horne JA, Pankhurst FL, Reyner LA, Hume K, Diamond ID. A field study of sleep disturbance: effects of aircraft noise and other factors on 5,742 nights of actimetrically monitored sleep in a large subject sample. Sleep 1994;17:146-159.
7. Ohrstrom E, Hadzibajramovic E, Holmes M, Svensson H. Effects of road traffic noise on sleep: studies on children and adults. J Environ Psychol 2006;26:116-126.
8. Basner M, Glatz C, Griefahn B, Penzel T, Samel A. Aircraft noise: effects on macroand micro-structure of sleep. Sleep Med 2008;9:382-387.
9. Basner M. Nocturnal aircraft noise increases objectively assessed daytime sleepiness. Somnologie 2008;12:110-117.
10. Elmenhorst EM, Elmenhorst D,Wenzel J, Quehl J, Mueller U, Maass H, Vejvoda M, Basner M. Effects of nocturnal aircraft noise on cognitive performance in the following morning: dose-response relationships in laboratory and field. Int Arch Occup Environ Health 2010;83:743-751.
11. Munzel T, Gori T, Babisch W, Basner M. Cardiovascular effects of environmental noise exposure. Eur Heart J 2014;35:829-836.
12. Basner M, Müller U, Elmenhorst E-M. Single and combined effects of air, road, and rail traffic noise on sleep and recuperation. Sleep 2011;34:11-23.
13. Pearsons K, Barber D, Tabachnick BG, Fidell S. Predicting noise-induced sleep disturbance. J Acoust Soc Am 1995;97:331-338.
14. Schmidt FP, Basner M, Kroger G, Weck S, Schnorbus B, Muttray A, Sariyar M, Binder H, Gori T,Warnholtz A, Munzel T. Effect of nighttime aircraft noise exposure on endothelial function and stress hormone release in healthy adults. Eur Heart J 2013;34:3508-3514a.
15. Babisch W. Cardiovascular effects of noise. Noise Health 2011;13:201-204.
16. Babisch W. The noise/stress concept, risk assessment and research needs. Noise Health 2002;4:1-11.
17. Schmidt F, Kolle K, Kreuder K, Schnorbus B, Wild P, Hechtner M, Binder H, Gori T, Munzel T. Nighttime aircraft noise impairs endothelial function and increases blood pressure in patients with or at high risk for coronary artery disease. Clin Res Cardiol 2015;104:23-30.
18. Golbidi S, Frisbee JC, Laher I. Chronic stress impacts the cardiovascular system: animal models and clinical outcomes. Am J Physiol Heart Circ Physiol 2015;308: H1476-H1498.
19. Floud S, Blangiardo M, Clark C, de Hoogh K, Babisch W, Houthuijs D, Swart W, Pershagen G, Katsouyanni K, Velonakis M, Vigna-Taglianti F, Cadum E, Hansell AL. Exposure to aircraft and road traffic noise and associations with heart disease and stroke in six European countries: a cross-sectional study. Environ Health 2013;12:89.
20. Wu CC, Chen SJ, Yen MH. Attenuation of endothelium-dependent relaxation in mesenteric artery during noise-induced hypertension. J Biomed Sci 1994;1:49-53.
21. Wu CC, Chen SJ, Yen MH. Effects of noise on blood pressure and vascular reactivities. Clin Exp Pharmacol Physiol 1992;19:833-838.
22. Haralabidis AS, Dimakopoulou K, Vigna-Taglianti F, Giampaolo M, Borgini A, Dudley ML, Pershagen G, Bluhm G, Houthuijs D, Babisch W, Velonakis M, Katsouyanni K, Jarup L, Consortium H. Acute effects of night-time noise exposure on blood pressure in populations living near airports. Eur Heart J 2008;29:658-664.
23. Ekundayo OJ, Allman RM, Sanders PW, Aban I, Love TE, Arnett D, Ahmed A. Isolated systolic hypertension and incident heart failure in older adults: a propensitymatched study. Hypertension 2009;53:458-465.
24. Bach J, Endler G, Winkelmann BR, Boehm BO, MaerzW, Mannhalter C, Hellstern P. Coagulation factor XII (FXII) activity, activated FXII, distribution of FXII C46T gene polymorphism and coronary risk. J Thromb Haemost 2008;6:291-296.
25. Lessiani G, Falco A, Nicolucci E, Rolandi G, Davi G. Deep venous thrombosis and previous myocardial infarction in mild factor XII deficiency: a risk factor for both venous and arterial thrombosis. J Thromb Thrombolysis 2009;27:348-351.
26. Cappuccio FP, Cooper D, D'Elia L, Strazzullo P, Miller MA. Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. Eur Heart J 2011;32:1484-1492.
27. Irwin MR, Olmstead R, Carroll JE. Sleep disturbance, sleep duration, and inflammation: a systematic review and meta-analysis of cohort studies and experimental sleep deprivation. Biological Psych 2016;80:40-52.
28. Selander J, Bluhm G, Theorell T, Pershagen G, Babisch W, Seiffert I, Houthuijs D, Breugelmans O, Vigna-Taglianti F, Antoniotti MC, Velonakis E, Davou E, Dudley ML, Jarup L, Consortium H. Saliva cortisol and exposure to aircraft noise in six European countries. Environ Health Perspect 2009;117:1713-1717.
29. Khanfer R, Lord JM, Phillips AC. Neutrophil function and cortisol:DHEAS ratio in bereaved older adults. Brain Behav Immun 2011;25:1182-1186.
30. Maschke C, Rupp T, Hecht K. The influence of stressors on biochemical reactions - a review of present scientific findings with noise. Int J Hyg Environ Health 2000; 203:45-53.
31. Jarup L, Babisch W, Houthuijs D, Pershagen G, Katsouyanni K, Cadum E, Dudley ML, Savigny P, Seiffert I, Swart W, Breugelmans O, Bluhm G, Selander J, Haralabidis A, Dimakopoulou K, Sourtzi P, Velonakis M, Vigna-Taglianti F. Hypertension and exposure to noise near airports: the HYENA study. Environ Health Perspect 2008;116:329-333.
32. BabischW, Ising H, Gallacher JEJ, Sweetnam PM, Elwood PC. Traffic noise and cardiovascular risk: the caerphilly and speedwell studies, third phase-10-year follow up. Arch Environ Health 1999;54:210-216.
33. Dratva J, Phuleria HC, Foraster M, Gaspoz J-M, Keidel D, Künzli N, Liu LJS, Pons M, Zemp E, Gerbase MW, Schindler C. Transportation noise and blood pressure in a population-based sample of adults. Environ Health Perspect 2012;120:50-55.
34. Carrington MJ, Trinder J. Blood pressure and heart rate during continuous experimental sleep fragmentation in healthy adults. Sleep 2008;31:1701-1712.
35. Lercher P, Widmann U, Kofler W. Transportation noise and blood pressure: the importance of modifying factors. Internoise 2000;4:1-5.
36. Barregard L, Sallsten G, Gustafson P, Andersson L, Johansson L, Basu S, Stigendal L. Experimental exposure to wood-smoke particles in healthy humans: effects on markers of inflammation, coagulation, and lipid peroxidation. Inhal Toxicol 2006; 18:845-853.
37. Tornqvist H, Mills NL, Gonzalez M, Miller MR, Robinson SD, Megson IL, MacneeW, Donaldson K, Soderberg S, Newby DE, Sandstrom T, Blomberg A. Persistent endothelial dysfunction in humans after diesel exhaust inhalation. Am J Respir Crit Care Med 2007;176:395-400.
38. Peretz A, Peck EC, Bammler TK, Beyer RP, Sullivan JH, Trenga CA, Srinouanprachnah S, Farin FM, Kaufman JD. Diesel exhaust inhalation and assessment of peripheral blood mononuclear cell gene transcription effects: an exploratory study of healthy human volunteers. Inhal Toxicol 2007;19:1107-1119.
39. Hiraiwa K, van Eeden SF. Contribution of lung macrophages to the inflammatory responses induced by exposure to air pollutants. Mediators Inflamm 2013;2013: 619523.
40. Goto Y, Ishii H, Hogg JC, Shih CH, Yatera K, Vincent R, van Eeden SF. Particulate matter air pollution stimulates monocyte release from the bone marrow. Am J Respir Crit Care Med 2004;170:891-897.
41. Kampfrath T, Maiseyeu A, Ying Z, Shah Z, Deiuliis JA, Xu X, Kherada N, Brook RD, Reddy KM, Padture NP, Parthasarathy S, Chen LC, Moffatt-Bruce S, Sun Q, Morawietz H, Rajagopalan S. Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways. Circ Res 2011; 108:716-726.
42. Deiuliis JA, Kampfrath T, Zhong J, Oghumu S, Maiseyeu A, Chen LC, Sun Q, Satoskar AR, Rajagopalan S. Pulmonary T cell activation in response to chronic particulate air pollution. Am J Physiol Lung Cell Mol Physiol 2012;302:L399-L409.
43. Rajagopalan S, Brook RD. Air pollution and type 2 diabetes: mechanistic insights. Diabetes 2012;61:3037-3045.
44. Liu C, Ying Z, Harkema J, Sun Q, Rajagopalan S. Epidemiological and experimental links between air pollution and type 2 diabetes. Toxicol Pathol 2013;41:361-373.
45. Simon SA, LiedtkeW. How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. J Clin Invest 2008;118:2383-2386.
46. Dominici F, Peng RD, Ebisu K, Zeger SL, Samet JM, Bell ML. Does the effect of PM10 on mortality depend on PM nickel and vanadium content? A reanalysis of the NMMAPS data. Environ Health Perspect 2007;115:1701-1703.
47. Liberda EN, Cuevas AK, Gillespie PA, Grunig G, Qu Q, Chen LC. Exposure to inhaled nickel nanoparticles causes a reduction in number and function of bone marrow endothelial progenitor cells. Inhal Toxicol 2010;22(Suppl. 2):95-99.
48. Brook RD, Rajagopalan S, Pope CA 3rd, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, Peters A, Siscovick D, Smith SC Jr, Whitsel L, Kaufman JD, on behalf of the American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation 2010;121:2331-2378.
49. Ying Z, Xu X, Bai Y, Zhong J, Chen M, Liang Y, Zhao J, Liu D, Morishita M, Sun Q, Spino C, Brook RD, Harkema JR, Rajagopalan S. Long-term exposure to concentrated ambient PM2.5 increases mouse blood pressure through abnormal activation of the sympathetic nervous system: a role for hypothalamic inflammation. Environ Health Perspect 2014;122:79-86.
50. Ying Z, Yue P, Xu X, Zhong M, Sun Q, Mikolaj M, Wang A, Brook RD, Chen LC, Rajagopalan S. Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase. Am J Physiol Heart Circ Physiol 2009;296:H1540-H1550.
51. Sun Q, Yue P, Ying Z, Cardounel AJ, Brook RD, Devlin R, Hwang J-SS, Zweier JL, Chen LC, Rajagopalan S. Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK. Arterioscler Thromb Vasc Biol 2008;28:1760-1766.
52. Mills NL, Tornqvist H, Robinson SD, Gonzalez M, Darnley K, MacNee W, Boon NA, Donaldson K, Blomberg A, Sandstrom T, Newby DE. Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 2005;112:3930-3936.
53. ShahAP, PietropaoliAP, Frasier LM, SpeersDM,ChalupaDC,Delehanty JM,Huang LS, Utell MJ, Frampton MW. Effect of inhaled carbon ultrafine particles on reactive hyperemia in healthy human subjects. Environ Health Perspect 2008;116:375-380.
54. Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, Seagrave JC, Knuckles TL, Campen MJ. Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. Arterioscler Thromb Vasc Biol 2009;29: 511-517.
55. Peretz A, Sullivan JH, Leotta DF, Trenga CA, Sands FN, Allen J, Carlsten C, Wilkinson CW, Gill EA, Kaufman JD. Diesel exhaust inhalation elicits acute vasoconstriction in vivo. Environ Health Perspect 2008;116:937-942.
56. Mills NL, Tornqvist H, Gonzalez MC, Vink E, Robinson SD, Soderberg S, Boon NA, Donaldson K, Sandstrom T, Blomberg A, Newby DE. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N Engl J Med 2007;357:1075-1082.
57. Brook RD, Urch B, Dvonch JT, Bard RL, Speck M, Keeler G, Morishita M, Marsik FJ, Kamal AS, Kaciroti N, Harkema J, Corey P, Silverman F, Gold DR, Wellenius G, Mittleman MA, Rajagopalan S, Brook JR. Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans. Hypertension 2009;54:659-667.
58. Mills NL, Robinson SD, Fokkens PH, Leseman DL, Miller MR, Anderson D, Freney EJ, Heal MR, Donovan RJ, Blomberg A, Sandstrom T, MacNee W, Boon NA, Donaldson K, Newby DE, Cassee FR. Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease. Environ Health Perspect 2008;116:709-715.
59. Wold LE, Ying Z, Hutchinson KR, Velten M, Gorr MW, Velten C, Youtz DJ,Wang A, Lucchesi PA, Sun Q, Rajagopalan S. Cardiovascular remodeling in response to longterm exposure to fine particulate matter air pollution. Circ Heart Fail 2012;5:452-461.
60. Campen MJ, Lund A, Rosenfeld M. Mechanisms linking traffic-related air pollution and atherosclerosis. Curr Opin Pulmonary Med 2012;18:155-160.
61. Rao X, Zhong J, Maiseyeu A, Gopalakrishnan B, Villamena FA, Chen LC, Harkema JR, Sun Q, Rajagopalan S. CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure. Circ Res 2014;115:770-780.
62. Tsou CL, PetersW, Si Y, Slaymaker S, Aslanian AM,Weisberg SP, Mack M, Charo IF. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest 2007;117:902-909.
63. Yin F, Lawal A, Ricks J, Fox JR, Larson T, Navab M, Fogelman AM, Rosenfeld ME, Araujo JA. Diesel exhaust induces systemic lipid peroxidation and development of dysfunctional pro-oxidant and pro-inflammatory high-density lipoprotein. Arterioscler Thromb Vasc Biol 2013;33:1153-1161.
64. Li R, Navab K, Hough G, Daher N, Zhang M, Mittelstein D, Lee K, Pakbin P, Saffari A, Bhetraratana M, Sulaiman D, Beebe T, Wu L, Jen N, Wine E, Tseng CH, Araujo JA, Fogelman A, Sioutas C, Navab M, Hsiai TK. Effect of exposure to atmospheric ultrafine particles on production of free fatty acids and lipid metabolites in the mouse small intestine. Environ Health Perspect 2015;123:34-41.
65. Sun Q, Wang A, Jin X, Natanzon A, Duquaine D, Brook RD, Aguinaldo JG, Fayad ZA, Fuster V, Lippmann M, Chen LC, Rajagopalan S. Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model. J Am Med Assoc 2005;294:3003-3010.
66. Campen MJ, Lund AK, Knuckles TL, Conklin DJ, Bishop B, Young D, Seilkop S, Seagrave J, Reed MD, McDonald JD. Inhaled diesel emissions alter atherosclerotic plaque composition in ApoE(-/-) mice. Toxicol Appl Pharmacol 2010;242: 310-317.
67. Lund AK, Lucero J, Harman M, Madden MC, McDonald JD, Seagrave JC, Campen MJ. The oxidized low-density lipoprotein receptor mediates vascular effects of inhaled vehicle emissions. Am J Respir Crit Care Med 2011;184:82-91.
68. Nemmar A, Hoet PH, Dinsdale D, Vermylen J, Hoylaerts MF, Nemery B. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 2003;107:1202-1208.
69. Lucking AJ, Lundback M, Mills NL, Faratian D, Barath SL, Pourazar J, Cassee FR, Donaldson K, Boon NA, Badimon JJ, Sandstrom T, Blomberg A, Newby DE. Diesel exhaust inhalation increases thrombus formation in man. Eur Heart J 2008;29: 3043-3051.
70. Newby DE, Mannucci PM, Tell GS, Baccarelli AA, Brook RD, Donaldson K, Forastiere F, Franchini M, Franco OH, Graham I, Hoek G, Hoffmann B, Hoylaerts MF, Kunzli N, Mills N, Pekkanen J, Peters A, Piepoli MF, Rajagopalan S, Storey RF, on behalf of EscWorking Group on Thrombosis EAfCP, Rehabilitation and Association ESCHF. Expert position paper on air pollution and cardiovascular disease. Eur Heart J 2015;36:83-93.