Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 4, 2009, Pages 511-517

  Lund, Amie K ^a   Lucero, Joann ^a   Lucas, Selitá ^a   Madden, Michael C ^b   McDonald, Jacob D ^a   Seagrave, Jean Clare ^a   Knuckles, Travis L ^a   Campen, Matthew J ^a  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Air pollution; Atherosclerosis; Endothelin 1; Matrix metalloproteinase; Reactive oxygen species

Indexed keywords

APOLIPOPROTEIN E; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; GASOLINE; GELATINASE A; GELATINASE B; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TEMPOL; TISSUE INHIBITOR OF METALLOPROTEINASE 2; AMINE OXIDE; ANTIOXIDANT; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE; MMP2 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE; NITRATE; NITRITE;

AIR POLLUTANT; AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INDUCTION; EXHAUST GAS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK FACTOR; ADOLESCENT; ADULT; ANIMAL; AORTA; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; ENZYMOLOGY; EXPOSURE; FEMALE; GENETICS; HUMAN; INFUSION PUMP; METABOLISM; MOUSE MUTANT; ORAL DRUG ADMINISTRATION; SPIN LABELING; TIME; UPREGULATION;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANIMALS; ANTIOXIDANTS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CYCLIC N-OXIDES; ENDOTHELIN-1; FEMALE; HUMANS; INFUSION PUMPS, IMPLANTABLE; INHALATION EXPOSURE; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; NITRATES; NITRITES; PEPTIDES, CYCLIC; REACTIVE OXYGEN SPECIES; RECEPTOR, ENDOTHELIN A; RNA, MESSENGER; SPIN LABELS; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UP-REGULATION; VEHICLE EMISSIONS; YOUNG ADULT;

EID: 63449126350     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.176107     Document Type: Article

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