Integrated genomic and molecular characterization of cervical cancer

Nature

Volumn 543, Issue 7645, 2017, Pages 378-384

  Burk, Robert D ^a   Chen, Zigui ^a   Saller, Charles ^b   Tarvin, Katherine ^b   Carvalho, Andre L ^c   Scapulatempo Neto, Cristovam ^c   Silveira, Henrique C ^c   Fregnani, José H ^c   Creighton, Chad J ^d   Anderson, Matthew L ^d   Castro, Patricia ^d   Wang, Sophia S ^e   Yau, Christina ^f   Benz, Christopher ^f   Gordon Robertson, A ^g   Mungall, Karen ^g   Lim, Lynette ^g   Bowlby, Reanne ^g   Sadeghi, Sara ^g   Brooks, Denise ^g   Sipahimalani, Payal ^g   Mar, Richard ^g   Ally, Adrian ^g   Clarke, Amanda ^g   Mungall, Andrew J ^g   Tam, Angela ^g   Lee, Darlene ^g   Chuah, Eric ^g   Schein, Jacqueline E ^g   Tse, Kane ^g   Kasaian, Katayoon ^g   Ma, Yussanne ^g   Marra, Marco A ^g   Mayo, Michael ^g   Balasundaram, Miruna ^g   Thiessen, Nina ^g   Dhalla, Noreen ^g   Carlsen, Rebecca ^g   Moore, Richard A ^g   Holt, Robert A ^g   Jones, Steven J M ^g   Wong, Tina ^g   Pantazi, Angeliki ^h   Parfenov, Michael ^h   Kucherlapati, Raju ^h   Hadjipanayis, Angela ^h   Seidman, Jonathan ^h   Kucherlapati, Melanie ^h   Ren, Xiaojia ^h   Xu, Andrew W ^h   Yang, Lixing ^h   Park, Peter J ^h   Lee, Semin ^h   Rabeno, Brenda ⁱ   Huelsenbeck Dill, Lori ⁱ   Borowsky, Mark ⁱ   Cadungog, Mark ⁱ   Iacocca, Mary ⁱ   Petrelli, Nicholas ⁱ   Swanson, Patricia ⁱ   Ojesina, Akinyemi I ^j,k,l   Le, Xuan ^m   Sandusky, George ⁿ   Adebamowo, Sally N ^o   Akeredolu, Teniola ^o   Adebamowo, Clement ^o   Reynolds, Sheila M ^p   Shmulevich, Ilya ^p   Shelton, Candace ^q   Crain, Daniel ^q   Mallery, David ^q   Curley, Erin ^q   Gardner, Johanna ^q   Penny, Robert ^q   Morris, Scott ^q   Shelton, Troy ^q   Liu, Jia ^r   Lolla, Laxmi ^r   Chudamani, Sudha ^r   Wu, Ye ^r   Birrer, Michael ^s   McLellan, Michael D ^t   Bailey, Matthew H ^t   Miller, Christopher A ^t   Wyczalkowski, Matthew A ^t   Fulton, Robert S ^t   Fronick, Catrina C ^t   Lu, Charles ^t   Mardis, Elaine R ^t   Appelbaum, Elizabeth L ^t   Schmidt, Heather K ^t   Fulton, Lucinda A ^t   Cordes, Matthew G ^t   Li, Tiandao ^t   Ding, Li ^t   Wilson, Richard K ^t   Rader, Janet S ^u   Behmaram, Behnaz ^u   Uyar, Denise ^u   Bradley, William ^u   Wrangle, John ^v   Pastore, Alessandro ^w   Levine, Douglas A ^w   Dao, Fanny ^w   Gao, Jianjiong ^w   Schultz, Nikolaus ^w   Sander, Chris ^w   Ladanyi, Marc ^w   Einstein, Mark ^x   Teeter, Randall ^x   Benz, Stephen ^y   Wentzensen, Nicolas ^z   Felau, Ina ^z   Zenklusen, Jean C ^z   Bodelon, Clara ^z   Demchok, John A ^z   Yang, Liming ^z   Sheth, Margi ^z   Ferguson, Martin L ^z   Tarnuzzer, Roy ^z   Yang, Hannah ^z   Schiffman, Mark ^z   Zhang, Jiashan ^z   Wang, Zhining ^z   Davidsen, Tanja ^z   Olaniyan, Olayinka ^aa   Hutter, Carolyn M ^ab   Sofia, Heidi J ^ab   Gordenin, Dmitry A ^ac   Chan, Kin ^ac   Roberts, Steven A ^ac   Klimczak, Leszek J ^ac   Van Waes, Carter ^ad   Chen, Zhong ^ad   Saleh, Anthony D ^ad   Cheng, Hui ^ad   Parfitt, Jeremy ^ae   Bartlett, John ^af   Albert, Monique ^af   Arnaout, Angel ^ag   Sekhon, Harman ^ag   Gilbert, Sebastien ^ag   Peto, Myron ^ah   Myers, Jerome ^ai   Harr, Jodi ^ai   Eckman, John ^ai   Bergsten, Julie ^ai   Tucker, Kelinda ^ai   Anne Zach, Leigh ^ai   Karlan, Beth Y ^aj   Lester, Jenny ^aj   Orsulic, Sandra ^aj   Sun, Qiang ^ak   Naresh, Rashi ^ak   Pihl, Todd ^ak   Wan, Yunhu ^ak   Zaren, Howard ^al   Sapp, Jennifer ^al   Miller, Judy ^al   Drwiega, Paul ^al   Murray, Bradley A ^k   Zhang, Hailei ^k   Cherniack, Andrew D ^k   Sougnez, Carrie ^k   Sekhar Pedamallu, Chandra ^k   Lichtenstein, Lee ^k   Meyerson, Matthew ^k   Noble, Michael S ^k   Heiman, David I ^k   Voet, Doug ^k   Getz, Gad ^k   Saksena, Gordon ^k   Kim, Jaegil ^k   Shih, Juliann ^k   Cho, Juok ^k   Lawrence, Michael S ^k   Gehlenborg, Nils ^k   Lin, Pei ^k   Beroukhim, Rameen ^k   Frazer, Scott ^k   Gabriel, Stacey B ^k   Schumacher, Steven E ^k   Leraas, Kristen M ^am   Lichtenberg, Tara M ^am   Zmuda, Erik ^am   Bowen, Jay ^am   Frick, Jessica ^am   Gastier Foster, Julie M ^am   Wise, Lisa ^am   Gerken, Mark ^am   Ramirez, Nilsa C ^am   Danilova, Ludmila ^an   Cope, Leslie ^an   Baylin, Stephen B ^an   Salvesen, Helga B ^ao   Vellano, Christopher P ^ap   Ju, Zhenlin ^ap   Diao, Lixia ^ap   Zhao, Hao ^ap   Chong, Zechen ^ap   Ryan, Michael C ^ap   Martinez Ledesma, Emmanuel ^ap   Verhaak, Roeland G ^ap   Averett Byers, Lauren ^ap   Yuan, Yuan ^ap   Chen, Ken ^ap   Ling, Shiyun ^ap   Mills, Gordon B ^ap   Lu, Yiling ^ap   Akbani, Rehan ^ap   Seth, Sahil ^ap   Liang, Han ^ap   Wang, Jing ^ap   Han, Leng ^ap   Weinstein, John N ^ap   Bristow, Christopher A ^ap   Zhang, Wei ^ap   Mahadeshwar, Harshad S ^ap   Sun, Huandong ^ap   Tang, Jiabin ^ap   Zhang, Jianhua ^ap   Song, Xingzhi ^ap   Protopopov, Alexei ^ap   Mills Shaw, Kenna R ^ap   Chin, Lynda ^ap   Olabode, Oluwole ^aq   DiSaia, Philip ^ar   Radenbaugh, Amie ^as   Haussler, David ^as   Zhu, Jingchun ^as   Stuart, Josh ^as   Chalise, Prabhakar ^at   Koestler, Devin ^at   Fridley, Brooke L ^at   Godwin, Andrew K ^at   Madan, Rashna ^at   Ciriello, Giovanni ^au   Martinez, Cathleen ^av   Higgins, Kelly ^av   Bocklage, Therese ^av   Todd Auman, J ^aw   Perou, Charles M ^aw   Tan, Donghui ^aw   Parker, Joel S ^aw   Hoadley, Katherine A ^aw   Wilkerson, Matthew D ^aw   Mieczkowski, Piotr A ^aw   Skelly, Tara ^aw   Veluvolu, Umadevi ^aw   Neil Hayes, D ^aw   Kimryn Rathmell, W ^aw   Hoyle, Alan P ^aw   Simons, Janae V ^aw   Wu, Junyuan ^aw   Mose, Lisle E ^aw   Soloway, Matthew G ^aw   Balu, Saianand ^aw   Meng, Shaowu ^aw   Jefferys, Stuart R ^aw   Bodenheimer, Tom ^aw   Shi, Yan ^aw   Roach, Jeffrey ^aw   Thorne, Leigh B ^aw   Boice, Lori ^aw   Huang, Mei ^aw   Jones, Corbin D ^aw   Zuna, Rosemary ^ax   Walker, Joan ^ax   Gunderson, Camille ^ax   Snowbarger, Carie ^ax   Brown, David ^ax   Moxley, Katherine ^ax   Moore, Kathleen ^ax   Andrade, Kelsi ^ax   Landrum, Lisa ^ax   Mannel, Robert ^ax   McMeekin, Scott ^ax   Johnson, Starla ^ax   Nelson, Tina ^ax   Elishaev, Esther ^ay   Dhir, Rajiv ^ay   Edwards, Robert ^ay   Bhargava, Rohit ^ay   Tiezzi, Daniel G ^az   Andrade, Jurandyr M ^az   Noushmehr, Houtan ^az   Gilberto Carlotti, Carlos ^az   da Cunha Tirapelli, Daniela Pretti ^az   Weisenberger, Daniel J ^ba   Van Den Berg, David J ^ba   Maglinte, Dennis T ^ba   Bootwalla, Moiz S ^ba   Lai, Phillip H ^ba   Triche, Timothy ^ba   Swisher, Elizabeth M ^bb   Agnew, Kathy J ^bb   Simon Shelley, Carl ^bc   Laird, Peter W ^bd   Schwarz, Julie ^be   Grigsby, Perry ^be   Mutch, David ^be   more..

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b Analytical Biological Services Inc   (United States)

^c BARRETOS CANCER HOSPITAL   (Brazil)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^f BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^g BRITISH COLUMBIA CANCER AGENCY   (Canada)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ HELEN F GRAHAM CANCER CENTER   (United States)

^j HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^k BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^l UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^m ILSBio LLC   (United States)

ⁿ INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^o CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^p INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^q International Genomics Consortium   (United States)

^r FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^s MASSACHUSETTS GENERAL HOSPITAL   (United States)

^t WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^u MEDICAL COLLEGE OF WISCONSIN   (United States)

^v MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^w MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^x MONTEFIORE MEDICAL CENTER   (United States)

^y NantOmics LLC   (United States)

^z NATIONAL CANCER INSTITUTE   (United States)

^aa NATIONAL HOSPITAL   (Nigeria)

^ab NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^ac NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^ad NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^ae LONDON HEALTH SCIENCES CENTRE   (Canada)

^af ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^ag UNIVERSITY OF OTTAWA   (Canada)

^ah OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^ai Penrose Hospital   (United States)

^aj CEDARS SINAI MEDICAL CENTER   (United States)

^ak GENERAL DYNAMICS   (United States)

^al St Joseph's/Candler Health System   (United States)

^am THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^an JOHNS HOPKINS UNIVERSITY   (United States)

^ao UNIVERSITY OF BERGEN   (Norway)

^ap UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^aq UNIVERSITY OF ABUJA   (Nigeria)

^ar UNIVERSITY OF CALIFORNIA   (United States)

^as UNIVERSITY OF CALIFORNIA   (United States)

^at UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^au UNIVERSITY OF LAUSANNE   (Switzerland)

^av UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^aw UNIVERSITY OF NORTH CAROLINA   (United States)

^ax UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^ay UNIVERSITY OF PITTSBURGH   (United States)

^az UNIVERSITY OF SÃO PAULO   (Brazil)

^ba UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^bb UNIVERSITY OF WASHINGTON   (United States)

^bc UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^bd VAN ANDEL RESEARCH INSTITUTE   (United States)

^be WASHINGTON UNIVERSITY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MRNA EDITING ENZYME CATALYTIC POLYPEPTIDE LIKE; ARID1A PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 3; HLA A ANTIGEN; K RAS PROTEIN; KERATIN; LAPATINIB; LONG UNTRANSLATED RNA; MESSENGER RNA; MICRORNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; SHKBP1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; UNTRANSLATED RNA; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; ARID1A PROTEIN, HUMAN; BCAR4 NON-CODING RNA, HUMAN; CASP8 PROTEIN, HUMAN; CASPASE 8; CD274 PROTEIN, HUMAN; ERBB3 PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NUCLEAR PROTEIN; PDCD1LG2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P21; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

CANCER; GENETIC ANALYSIS; GENOMICS; IMMUNE SYSTEM; MOLECULAR ANALYSIS; MUTATION; RNA; VIRUS;

ARTICLE; COPY NUMBER VARIATION; FEMALE; FRAMESHIFT MUTATION; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC VARIABILITY; GENOMICS; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN TISSUE; INDEL MUTATION; MISSENSE MUTATION; MUTAGENESIS; MUTATION RATE; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN MICROARRAY; RNA METHYLATION; SOMATIC MUTATION; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA; UTERUS CARCINOMA; WHOLE EXOME SEQUENCING; ADENOCARCINOMA; CLASSIFICATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MOLECULARLY TARGETED THERAPY; MUTATION; PROTEOMICS; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; UTERINE CERVICAL NEOPLASMS; VIRUS DNA CELL DNA INTERACTION;

HUMAN PAPILLOMAVIRUS;

ADENOCARCINOMA; ANTIGENS, CD274; APOBEC-1 DEAMINASE; CARCINOMA, SQUAMOUS CELL; CASPASE 8; FEMALE; GENOMICS; HLA-A ANTIGENS; HUMAN PAPILLOMAVIRUS 16; HUMANS; KERATINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOLECULAR TARGETED THERAPY; MUTATION; NUCLEAR PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROTEIN-SERINE-THREONINE KINASES; PROTEOMICS; PROTO-ONCOGENE PROTEINS P21(RAS); PTEN PHOSPHOHYDROLASE; RECEPTOR, ERBB-3; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RNA, LONG NONCODING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UTERINE CERVICAL NEOPLASMS; VIRUS INTEGRATION;

EID: 85016138846     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature21386     Document Type: Article

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