The BioGRID interaction database: 2017 update

Nucleic Acids Research

Volumn 45, Issue D1, 2017, Pages D369-D379

  Chatr Aryamontri, Andrew ^a   Oughtred, Rose ^b   Boucher, Lorrie ^c   Rust, Jennifer ^b   Chang, Christie ^b   Kolas, Nadine K ^c   O'Donnell, Lara ^c   Oster, Sara ^c   Theesfeld, Chandra ^b   Sellam, Adnane ^d   Stark, Chris ^c   Breitkreutz, Bobby Joe ^c   Dolinski, Kara ^b   Tyers, Mike ^a,c  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^b PRINCETON UNIVERSITY   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

^d LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACCESS TO INFORMATION; ARTICLE; BIOLOGICAL FUNCTIONS; BIOLOGICAL GENERAL REPOSITORY FOR INTERACTION DATABASE; BIOMEDICINE; CHEMICAL INTERACTION; DISEASES; DRUG DATABASE; DRUG RESEARCH; DRUG TARGETING; DRUGBANK DATABASE; GENE INTERACTION; GENETIC DATABASE; GENETIC SCREENING; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN INTERACTION; PROTEIN PROCESSING; PUBLICATION; STANDARDIZATION; ANIMAL; BIOLOGY; CHEMISTRY; DATA MINING; GENETICS; HUMAN; INFORMATION PROCESSING; METABOLISM; PROCEDURES; PROTEIN PROTEIN INTERACTION; SOFTWARE;

PROTEIN;

ANIMALS; COMPUTATIONAL BIOLOGY; DATA CURATION; DATA MINING; DATABASES, GENETIC; HUMANS; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SOFTWARE;

EID: 85016136235     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw1102     Document Type: Article

References (82)

1. Uetz, P., Giot, L., Cagney, G., Mansfeld, T.A., Judson, R.S., Knight, J.R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P. et al. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature, 403, 623-627.
2. Ho, Y., Gruhler, A., Heilbut, A., Bader, G.D., Moore, L., Adams, S.L., Millar, A., Taylor, P., Bennett, K., Boutilier, K. et al. (2002) Systematic identifcation of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature, 415, 180-183.
3. Gavin, A.C., Bosche, M., Krause, R., Grandi, P., Marzioch, M., Bauer, A., Schultz, J., Rick, J.M., Michon, A.M., Cruciat, C.M. et al. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature, 415, 141-147.
4. Tong, A.H., Evangelista, M., Parsons, A.B., Xu, H., Bader, G.D., Page, N., Robinson, M., Raghibizadeh, S., Hogue, C.W., Bussey, H. et al. (2001) Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science, 294, 2364-2368.
5. Rolland, T., Tasan, M., Charloteaux, B., Pevzner, S.J., Zhong, Q., Sahni, N., Yi, S., Lemmens, I., Fontanillo, C., Mosca, R. et al. (2014) A proteome-scale map of the human interactome network. Cell, 159, 1212-1226.
6. Huttlin, E.L., Ting, L., Bruckner, R.J., Gebreab, F., Gygi, M.P., Szpyt, J., Tam, S., Zarraga, G., Colby, G., Baltier, K. et al. (2015) The BioPlex network: a systematic exploration of the human interactome. Cell, 162, 425-440.
7. Yang, X., Coulombe-Huntington, J., Kang, S., Sheynkman, G.M., Hao, T., Richardson, A., Sun, S., Yang, F., Shen, Y.A., Murray, R.R. et al. (2016) Widespread expansion of protein interaction capabilities by alternative splicing. Cell, 164, 805-817.
8. Li, X., Gianoulis, T.A., Yip, K.Y., Gerstein, M. and Snyder, M. (2010) Extensive in vivo metabolite-protein interactions revealed by large-scale systematic analyses. Cell, 143, 639-650.
9. Gallego, O., Betts, M.J., Gvozdenovic-Jeremic, J., Maeda, K., Matetzki, C., Aguilar-Gurrieri, C., Beltran-Alvarez, P., Bonn, S., Fernandez-Tornero, C., Jensen, L.J. et al. (2010) A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae. Mol. Syst. Biol., 6, 430.
10. Sahni, N., Yi, S., Taipale, M., Fuxman Bass, J.I., Coulombe-Huntington, J., Yang, F., Peng, J., Weile, J., Karras, G.I., Wang, Y. et al. (2015) Widespread macromolecular interaction perturbations in human genetic disorders. Cell, 161, 647-660.
11. Hofree, M., Shen, J.P., Carter, H., Gross, A. and Ideker, T. (2013) Network-based stratifcation of tumor mutations. Nat. Methods, 10, 1108-1115.
12. Sun, S., Yang, F., Tan, G., Costanzo, M., Oughtred, R., Hirschman, J., Theesfeld, C.L., Bansal, P., Sahni, N., Yi, S. et al. (2016) An extended set of yeast-based functional assays accurately identifes human disease mutations. Genome Res., 26, 670-680.
13. Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L.B., Martin, S., Wedge, D.C. et al. (2016) Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature, 534, 47-54.
14. Consortium, Roadmap, Epigenomics, Kundaje, A., Meuleman, W., Ernst, J., Bilenky, M., Yen, A., Heravi-Moussavi, A., Kheradpour, P., Zhang, Z., Wang, J. et al. (2015) Integrative analysis of 111 reference human epigenomes. Nature, 518, 317-330.
15. Srivas, R., Shen, J.P., Yang, C.C., Sun, S.M., Li, J., Gross, A.M., Jensen, J., Licon, K., Bojorquez-Gomez, A., Klepper, K. et al. (2016) A network of conserved synthetic lethal interactions for exploration of precision cancer therapy. Mol. Cell, 63, 514-525.
16. Breitkreutz, B.J., Stark, C. and Tyers, M. (2003) The GRID: the general repository for interaction datasets. Genome Biol., 4, R23.
17. Reguly, T., Breitkreutz, A., Boucher, L., Breitkreutz, B.J., Hon, G.C., Myers, C.L., Parsons, A., Friesen, H., Oughtred, R., Tong, A. et al. (2006) Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. J. Biol., 5, 11.
18. Muller, H.M., Kenny, E.E. and Sternberg, P.W. (2004) Textpresso: an ontology-based information retrieval and extraction system for biological literature. PLoS Biol., 2, e309.
19. Kim, S., Kwon, D., Shin, S.Y. and Wilbur, W.J. (2012) PIE the search: searching PubMed literature for protein interaction information. Bioinformatics, 28, 597-598.
20. Islamaj Dogan, R., Kim, S., Chatr-Aryamontri, A., Chang, C.S., Oughtred, R., Rust, J., Wilbur, W.J., Comeau, D.C., Dolinski, K. and Tyers, M. (2016) The BioC-BioGRID corpus: full text articles annotated for curation of protein-protein and genetic interactions. Database (Oxford), in press.
21. Ruzicka, L., Bradford, Y.M., Frazer, K., Howe, D.G., Paddock, H., Ramachandran, S., Singer, A., Toro, S., Van Slyke, C.E., Eagle, A.E. et al. (2015) ZFIN, The zebrafsh model organism database: Updates and new directions. Genesis, 53, 498-509.
22. Bult, C.J., Eppig, J.T., Blake, J.A., Kadin, J.A., Richardson, J.E. and Mouse Genome Database Group. (2016) Mouse genome database 2016. Nucleic Acids Res., 44, D840-D847.
23. McDowall, M.D., Harris, M.A., Lock, A., Rutherford, K., Staines, D.M., Bahler, J., Kersey, P.J., Oliver, S.G. and Wood, V. (2015) PomBase 2015: updates to the fssion yeast database. Nucleic Acids Res., 43, D656-D661.
24. Attrill, H., Falls, K., Goodman, J.L., Millburn, G.H., Antonazzo, G., Rey, A.J., Marygold, S.J. and FlyBase Consortium (2016) FlyBase: establishing a Gene Group resource for Drosophila melanogaster. Nucleic Acids Res., 44, D786-D792.
25. Sheppard, T.K., Hitz, B.C., Engel, S.R., Song, G., Balakrishnan, R., Binkley, G., Costanzo, M.C., Dalusag, K.S., Demeter, J., Hellerstedt, S.T. et al. (2016) The Saccharomyces Genome Database Variant Viewer. Nucleic Acids Res., 44, D698-D702.
26. Howe, K.L., Bolt, B.J., Cain, S., Chan, J., Chen, W.J., Davis, P., Done, J., Down, T., Gao, S., Grove, C. et al. (2016) WormBase 2016: expanding to enable helminth genomic research. Nucleic Acids Res., 44, D774-D780.
27. Szklarczyk, D., Franceschini, A., Wyder, S., Forslund, K., Heller, D., Huerta-Cepas, J., Simonovic, M., Roth, A., Santos, A., Tsafou, K.P. et al. (2015) STRING v10: protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res., 43, D447-D452.
28. UniProt Consortium. (2015) UniProt: a hub for protein information. Nucleic Acids Res., 43, D204-D212.
29. NCBI Resource Coordinators. (2016) Database resources of the National Center for Biotechnology Information. Nucleic Acids Res., 44, D7-D19.
30. Cerami, E.G., Gross, B.E., Demir, E., Rodchenkov, I., Babur, O., Anwar, N., Schultz, N., Bader, G.D. and Sander, C. (2011) Pathway Commons, a web resource for biological pathway data. Nucleic Acids Res., 39, D685-D690.
31. Warde-Farley, D., Donaldson, S.L., Comes, O., Zuberi, K., Badrawi, R., Chao, P., Franz, M., Grouios, C., Kazi, F., Lopes, C.T. et al. (2010) The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res., 38, W214-W220.
32. Orchard, S., Kerrien, S., Abbani, S., Aranda, B., Bhate, J., Bidwell, S., Bridge, A., Briganti, L., Brinkman, F.S., Cesareni, G. et al. (2012) Protein interaction data curation: the International Molecular Exchange (IMEx) Consortium. Nat. Methods, 9, 345-350.
33. Chatr-Aryamontri, A., Breitkreutz, B.J., Oughtred, R., Boucher, L., Heinicke, S., Chen, D., Stark, C., Breitkreutz, A., Kolas, N., O'Donnell, L. et al. (2015) The BioGRID interaction database: 2015 update. Nucleic Acids Res., 43, D470-D478.
34. Kerrien, S., Orchard, S., Montecchi-Palazzi, L., Aranda, B., Quinn, A.F., Vinod, N., Bader, G.D., Xenarios, I., Wojcik, J., Sherman, D. et al. (2007) Broadening the horizon-level 2.5 of the HUPO-PSI format for molecular interactions. BMC Biol., 5, 44.
35. Roux, P.P. and Thibault, P. (2013) The coming of age of phosphoproteomics-from large data sets to inference of protein functions. Mol. Cell Proteomics, 12, 3453-3464.
36. Sadowski, I., Breitkreutz, B.J., Stark, C., Su, T.C., Dahabieh, M., Raithatha, S., Bernhard, W., Oughtred, R., Dolinski, K., Barreto, K. et al. (2013) The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update. Database (Oxford), 2013, bat026.
37. Law, V., Knox, C., Djoumbou, Y., Jewison, T., Guo, A.C., Liu, Y., Maciejewski, A., Arndt, D., Wilson, M., Neveu, V. et al. (2014) DrugBank 4.0: shedding new light on drug metabolism. Nucleic Acids Res., 42, D1091-D1097.
38. Skrzypek, M.S., Binkley, J., Binkley, G., Miyasato, S.R., Simison, M. and Sherlock, G. (2016) The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifers and visualization of high throughput sequencing data. Nucleic Acids Res., doi:10.1093/nar/gkw924.
39. Berardini, T.Z., Reiser, L., Li, D., Mezheritsky, Y., Muller, R., Strait, E. and Huala, E. (2015) The Arabidopsis Information Resource: Making and mining the "gold standard" annotated reference plant genome. Genesis, 53, 474-485.
40. Bernards, A. (2006) Ras superfamily and interacting proteins database. Methods Enzymol., 407, 1-9.
41. Mizushima, N., Yoshimori, T. and Ohsumi, Y. (2011) The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol., 27, 107-132.
42. Dirks, P.B. (2010) Brain tumor stem cells: the cancer stem cell hypothesis writ large. Mol. Oncol, 4, 420-430.
43. Brennan, C.W., Verhaak, R.G., McKenna, A., Campos, B., Noushmehr, H., Salama, S.R., Zheng, S., Chakravarty, D., Sanborn, J.Z., Berman, S.H. et al. (2013) The somatic genomic landscape of glioblastoma. Cell, 155, 462-477.
44. Cancer Genome Atlas Research Network. (2008) Comprehensive genomic characterization defnes human glioblastoma genes and core pathways. Nature, 455, 1061-1068.
45. Gene Ontology Consortium. (2015) Gene Ontology Consortium: going forward. Nucleic Acids Res., 43, D1049-D1056.
46. Costanzo, M., Van der Sluis, B., Koch, E.N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S.D. et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science, 353, aaf1420.
47. Pastur-Romay, L.A., Cedron, F., Pazos, A. and Porto-Pazos, A.B. (2016) Deep artifcial neural networks and neuromorphic chips for big data analysis: pharmaceutical and bioinformatics applications. Int J Mol. Sci, 17, E1313.
48. Fang, R., Schindelman, G., Van Auken, K., Fernandes, J., Chen, W., Wang, X., Davis, P., Tuli, M.A., Marygold, S.J., Millburn, G. et al. (2012) Automatic categorization of diverse experimental information in the bioscience literature. BMC Bioinformatics, 13, 16.
49. Van Auken, K., Fey, P., Berardini, T.Z., Dodson, R., Cooper, L., Li, D., Chan, J., Li, Y., Basu, S., Muller, H.M. et al. (2012) Text mining in the biocuration workfow: applications for literature curation at WormBase, DictyBase and TAIR. Database (Oxford), 2012, bas040.
50. Torii, M., Arighi, C.N., Li, G., Wang, Q., Wu, C.H. and Vijay-Shanker, K. (2015) RLIMS-P 2.0: A generalizable rule-based information extraction system for literature mining of protein phosphorylation information. IEEE/ACM Trans. Comput. Biol. Bioinform., 12, 17-29.
51. Kim, S., Shin, S.Y., Lee, I.H., Kim, S.J., Sriram, R. and Zhang, B.T. (2008) PIE: an online prediction system for protein-protein interactions from text. Nucleic Acids Res., 36, W411-W415.
52. Wang, Q., Abdul, S.S., Almeida, L., Ananiadou, S., Balderas-Martinez, Y.I., Batista-Navarro, R., Campos, D., Chilton, L., Chou, H.J., Contreras, G. et al. (2016) Overview of the interactive task in BioCreative V. Database (Oxford), 2016, baw119.
53. Chatr-Aryamontri, A., Winter, A., Perfetto, L., Briganti, L., Licata, L., Iannuccelli, M., Castagnoli, L., Cesareni, G. and Tyers, M. (2011) Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases. BMC Bioinformatics, 12(Suppl 8), S8.
54. Krallinger, M., Vazquez, M., Leitner, F., Salgado, D., Chatr-Aryamontri, A., Winter, A., Perfetto, L., Briganti, L., Licata, L., Iannuccelli, M. et al. (2011) The protein-protein interaction tasks of BioCreative III: classifcation/ranking of articles and linking bio-ontology concepts to full text. BMC Bioinformatics, 12(Suppl 8), S3.
55. Kim, S., Islamaj Dogan, R., Chatr-Aryamontri, A., Chang, C.S., Oughtred, R., Rust, J., Batista-Navarro, R., Carter, J., Ananiadou, S., Matos, S. et al. (2016) BioCreative V BioC track overview: collaborative biocurator assistant task for BioGRID. Database (Oxford), 2016, baw121.
56. Comeau, D.C., Islamaj Dogan, R., Ciccarese, P., Cohen, K.B., Krallinger, M., Leitner, F., Lu, Z., Peng, Y., Rinaldi, F., Torii, M. et al. (2013) BioC: a minimalist approach to interoperability for biomedical text processing. Database (Oxford), 2013, bat064.
57. Groza, T., Kohler, S., Moldenhauer, D., Vasilevsky, N., Baynam, G., Zemojtel, T., Schriml, L.M., Kibbe, W.A., Schofeld, P.N., Beck, T. et al. (2015) The human phenotype ontology: semantic unifcation of common and rare disease. Am. J. Hum. Genet., 97, 111-124.
58. McMurry, J.A., Kohler, S., Washington, N.L., Balhoff, J.P., Borromeo, C., Brush, M., Carbon, S., Conlin, T., Dunn, N., Engelstad, M. et al. (2016) Navigating the phenotype frontier: The Monarch Initiative. Genetics, 203, 1491-1495.
59. Wang, T., Birsoy, K., Hughes, N.W., Krupczak, K.M., Post, Y., Wei, J.J., Lander, E.S. and Sabatini, D.M. (2015) Identifcation and characterization of essential genes in the human genome. Science, 350, 1096-1101.
60. Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K.R., MacLeod, G., Mis, M., Zimmermann, M., Fradet-Turcotte, A., Sun, S. et al. (2015) High-resolution CRISPR screens reveal ftness genes and genotype-specifc cancer liabilities. Cell, 163, 1515-1526.
61. Wishart, D.S., Jewison, T., Guo, A.C., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E. et al. (2013) HMDB 3.0-The Human Metabolome Database in 2013. Nucleic Acids Res., 41, D801-D807.
62. Wishart, D., Arndt, D., Pon, A., Sajed, T., Guo, A.C., Djoumbou, Y., Knox, C., Wilson, M., Liang, Y., Grant, J. et al. (2015) T3DB: the toxic exposome database. Nucleic Acids Res., 43, D928-D934.
63. Gilson, M.K., Liu, T., Baitaluk, M., Nicola, G., Hwang, L. and Chong, J. (2016) BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. Nucleic Acids Res., 44, D1045-D1053.
64. Davis, A.P., Grondin, C.J., Lennon-Hopkins, K., Saraceni-Richards, C., Sciaky, D., King, B.L., Wiegers, T.C. and Mattingly, C.J. (2015) The Comparative Toxicogenomics Database's 10th year anniversary: update 2015. Nucleic Acids Res., 43, D914-D920.
65. Qin, C., Zhang, C., Zhu, F., Xu, F., Chen, S.Y., Zhang, P., Li, Y.H., Yang, S.Y., Wei, Y.Q., Tao, L. et al. (2014) Therapeutic target database update 2014: a resource for targeted therapeutics. Nucleic Acids Res., 42, D1118-D1123.
66. Seiler, K.P., George, G.A., Happ, M.P., Bodycombe, N.E., Carrinski, H.A., Norton, S., Brudz, S., Sullivan, J.P., Muhlich, J., Serrano, M. et al. (2008) ChemBank: a small-molecule screening and cheminformatics resource database. Nucleic Acids Res., 36, D351-D359.
67. Whirl-Carrillo, M., McDonagh, E.M., Hebert, J.M., Gong, L., Sangkuhl, K., Thorn, C.F., Altman, R.B. and Klein, T.E. (2012) Pharmacogenomics knowledge for personalized medicine. Clin. Pharmacol. Ther., 92, 414-417.
68. Griffth, M., Griffth, O.L., Coffman, A.C., Weible, J.V., McMichael, J.F., Spies, N.C., Koval, J., Das, I., Callaway, M.B., Eldred, J.M. et al. (2013) DGIdb: mining the druggable genome. Nat. Methods, 10, 1209-1210.
69. Wang, Y., Suzek, T., Zhang, J., Wang, J., He, S., Cheng, T., Shoemaker, B.A., Gindulyte, A. and Bryant, S.H.(2014) PubChem BioAssay: 2014 update. Nucleic Acids Res., 42, D1075-D1082.
70. Davies, M., Nowotka, M., Papadatos, G., Dedman, N., Gaulton, A., Atkinson, F., Bellis, L. and Overington, J.P. (2015) ChEMBL web services: streamlining access to drug discovery data and utilities. Nucleic Acids Res., 43, W612-W620.
71. Franz, M., Lopes, C.T., Huck, G., Dong, Y., Sumer, O. and Bader, G.D. (2016) Cytoscape.js: a graph theory library for visualisation and analysis. Bioinformatics, 32, 309-311.
72. del-Toro, N., Dumousseau, M., Orchard, S., Jimenez, R.C., Galeota, E., Launay, G., Goll, J., Breuer, K., Ono, K., Salwinski, L. et al. (2013) A new reference implementation of the PSICQUIC web service. Nucleic Acids Res., 41, W601-W606.
73. Liu, G., Zhang, J., Choi, H., Lambert, J.P., Srikumar, T., Larsen, B., Nesvizhskii, A.I., Raught, B., Tyers, M. and Gingras, A.C. (2012) Using ProHits to store, annotate, and analyze affnity purifcation-mass spectrometry (AP-MS) data. Curr. Protoc. Bioinformatics, doi:10.1002/0471250953.bi0816s39.
74. Razick, S., Magklaras, G. and Donaldson, I.M. (2008) iRefIndex: a consolidated protein interaction database with provenance. BMC Bioinformatics, 9, 405.
75. Murali, T., Pacifco, S., Yu, J., Guest, S., Roberts, G.G. 3rd and Finley, R.L. Jr (2011) DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila. Nucleic Acids Res., 39, D736-D743.
76. Lardenois, A., Gattiker, A., Collin, O., Chalmel, F. and Primig, M. (2010) GermOnline 4.0 is a genomics gateway for germline development, meiosis and the mitotic cell cycle. Database (Oxford), 2010, baq030.
77. Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B.J., Chang, C.S., Rust, J.M., Theesfeld, C.L., Heinicke, S., Breitkreutz, A., Chen, D., Hirschman, J. et al. (2016) Use of the BioGRID database for analysis of yeast protein and genetic interactions. Cold Spring Harb. Protoc., 2016, pdb prot088880.
78. Oughtred, R., Chatr-aryamontri, A., Breitkreutz, B.J., Chang, C.S., Rust, J.M., Theesfeld, C.L., Heinicke, S., Breitkreutz, A., Chen, D., Hirschman, J. et al. (2016) BioGRID: a resource for studying biological interactions in yeast. Cold Spring Harb. Protoc., 2016, pdb top080754.
79. Kwon, D., Kim, S., Shin, S.Y., Chatr-aryamontri, A. and Wilbur, W.J. (2014) Assisting manual literature curation for protein-protein interactions using BioQRator. Database (Oxford), 2014, bau067.
80. Shin, S.Y., Kim, S., Wilbur, W.J. and Kwon, D. (2016) BioC viewer: a web-based tool for displaying and merging annotations in BioC. Database (Oxford), 2016, baw106.
81. Rose, P.W., Prlic, A., Bi, C., Bluhm, W.F., Christie, C.H., Dutta, S., Green, R.K., Goodsell, D.S., Westbrook, J.D., Woo, J. et al. (2015) The RCSB Protein Data Bank: views of structural biology for basic and applied research and education. Nucleic Acids Res., 43, D345-D356.
82. Greene, C.S., Krishnan, A., Wong, A.K., Ricciotti, E., Zelaya, R.A., Himmelstein, D.S., Zhang, R., Hartmann, B.M., Zaslavsky, E., Sealfon, S.C. et al. (2015) Understanding multicellular function and disease with human tissue-specifc networks. Nat. Genet., 47, 569-576.