-
1
-
-
0005347881
-
Pathogenesis of postnatal thymectomy
-
McIntire KR, Sell S, Miller JF. Pathogenesis of postnatal thymectomy. Nature 1964;204:151-5.
-
(1964)
Nature
, vol.204
, pp. 151-155
-
-
McIntire, K.R.1
Sell, S.2
Miller, J.F.3
-
2
-
-
0014667395
-
Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
-
Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 1969;166:753-5.
-
(1969)
Science
, vol.166
, pp. 753-755
-
-
Nishizuka, Y.1
Sakakura, T.2
-
3
-
-
0029150110
-
Immunologic selftolerance maintained by activated t cells expressing il-2 receptor alphachains (cd25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic selftolerance maintained by activated T cells expressing IL-2 receptor alphachains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
4
-
-
84859416933
-
Regulatory t cells: Mechanisms of differentiation and function
-
Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol 2012;30:531-64.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
5
-
-
0036669298
-
Cd4 regulatory t cells prevent lethal autoimmunity in il-2rbeta-deficient mice implications for the nonredundant function of il-2
-
Malek TR, Yu A, Vincek V, Scibelli P, Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 2002;17:167-78.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
7
-
-
0036144888
-
Homeostasis and anergy of cd4(+)cd25(+) suppressor t cells in vivo
-
Gavin MA, Clarke SR, Negrou E, Gallegos A, Rudensky A. Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo. Nat Immunol 2002;3:33-41.
-
(2002)
Nat Immunol
, vol.3
, pp. 33-41
-
-
Gavin, M.A.1
Clarke, S.R.2
Negrou, E.3
Gallegos, A.4
Rudensky, A.5
-
8
-
-
0037385330
-
Foxp3 programs the development and function of cd4+cd25+ regulatory t cells
-
Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003;4:330-6.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
9
-
-
0037385314
-
An essential role for scurfin in cd4+cd25+ t regulatory cells
-
Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003;4:337-42.
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
10
-
-
0347785480
-
Control of regulatory t cell development by the transcription factor foxp3
-
Hori S,Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-61.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
11
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow ME, Jeffery EW, Hjerrild KA, Paeper B, Clark LB, Yasayko SA, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001; 27:68-73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
-
12
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, xlinked syndrome (ipex) is caused by mutations of foxp3
-
Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, et al. The immune dysregulation, polyendocrinopathy, enteropathy, Xlinked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001;27:20-1.
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
-
13
-
-
0035163909
-
Xlinked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, et al. Xlinked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001;27:18-20.
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
-
14
-
-
33745147867
-
Single-cell analysis of normal and foxp3-mutant human t cells: Foxp3 expression without regulatory t cell development
-
Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY, Stray-Pedersen A, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Nat Acad Sci U S A 2006;103:6659-64.
-
(2006)
Proc Nat Acad Sci U S A
, vol.103
, pp. 6659-6664
-
-
Gavin, M.A.1
Torgerson, T.R.2
Houston, E.3
DeRoos, P.4
Ho, W.Y.5
Stray-Pedersen, A.6
-
15
-
-
8344275995
-
Crucial role of foxp3 in the development and function of human cd25+cd4+ regulatory t cells
-
Yagi H, Nomura T, Nakamura K, Yamazaki S, Kitawaki T, et al. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol 2004;16:1643-56.
-
(2004)
Int Immunol
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
Nomura, T.2
Nakamura, K.3
Yamazaki, S.4
Kitawaki, T.5
-
16
-
-
15244354286
-
Regulatory t cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005;22:329-41.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
17
-
-
33847153417
-
Foxp3-dependent programme of regulatory t-cell differentiation
-
Gavin MA, Rasmussen JP, Fontenot JD, Vasta V, Manganiello VC, Beavo JA, et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 2007;445:771-5.
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
-
18
-
-
34247271308
-
Maintenance of the foxp3-dependent developmental program in mature regulatory t cells requires continued expression of foxp3
-
Williams LM, Rudensky AY. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 2007;8:277-84.
-
(2007)
Nat Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
19
-
-
77957371028
-
Stability of the regulatory t cell lineage in vivo
-
Rubtsov YP, Niec RE, Josefowicz S, Li L, Darce J, Mathis D, et al. Stability of the regulatory T cell lineage in vivo. Science 2010;329: 1667-71.
-
(2010)
Science
, vol.329
, pp. 1667-1671
-
-
Rubtsov, Y.P.1
Niec, R.E.2
Josefowicz, S.3
Li, L.4
Darce, J.5
Mathis, D.6
-
20
-
-
84862777225
-
Extrathymically generated regulatory t cells control mucosal th2 inflammation
-
Josefowicz SZ, Niec RE, Kim HY, Treuting P, Chinen T, Zheng Y, et al. Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012;482:395-9.
-
(2012)
Nature
, vol.482
, pp. 395-399
-
-
Josefowicz, S.Z.1
Niec, R.E.2
Kim, H.Y.3
Treuting, P.4
Chinen, T.5
Zheng, Y.6
-
21
-
-
76749133610
-
Role of conserved non-coding DNA elements in the foxp3 gene in regulatory t-cell fate
-
Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010;463:808-12.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
22
-
-
84908403082
-
Control of the inheritance of regulatory t cell identity by a cis element in the foxp3 locus
-
Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY. Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus. Cell 2014;158:749-63.
-
(2014)
Cell
, vol.158
, pp. 749-763
-
-
Feng, Y.1
Arvey, A.2
Chinen, T.3
Van Der Veeken, J.4
Gasteiger, G.5
Rudensky, A.Y.6
-
23
-
-
33645102841
-
An intersection between the self-reactive regulatory and nonregulatory t cell receptor repertoires
-
Hsieh CS, Zheng Y, Liang Y, Fontenot JD, Rudensky AY. An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. Nat Immunol 2006;7:401-10.
-
(2006)
Nat Immunol
, vol.7
, pp. 401-410
-
-
Hsieh, C.S.1
Zheng, Y.2
Liang, Y.3
Fontenot, J.D.4
Rudensky, A.Y.5
-
24
-
-
0348223787
-
Conversion of peripheral cd4+cd25 naive t cells to cd4+cd25+ regulatory t cells by tgf-beta induction of transcription factor foxp3
-
Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, et al. Conversion of peripheral CD4+CD25 naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003;198: 1875-86.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
25
-
-
84863619688
-
Extrathymic generation of regulatory t cells in placental mammals mitigates maternal-fetal conflict
-
Samstein RM, Josefowicz SZ, Arvey A, Treuting PM, Rudensky AY. Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell 2012;150:29-38.
-
(2012)
Cell
, vol.150
, pp. 29-38
-
-
Samstein, R.M.1
Josefowicz, S.Z.2
Arvey, A.3
Treuting, P.M.4
Rudensky, A.Y.5
-
26
-
-
84893849403
-
Microbial metabolites control gut inflammatory responses
-
Arpaia N, Rudensky AY. Microbial metabolites control gut inflammatory responses. Proc Natl Acad Sci U S A 2014;111:2058-9.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2058-2059
-
-
Arpaia, N.1
Rudensky, A.Y.2
-
27
-
-
33846485153
-
Regulatory t cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim JM, Rasmussen JP, Rudensky AY. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat Immunol 2007;8:191-7.
-
(2007)
Nat Immunol
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
28
-
-
53749094183
-
Ctla-4 control over foxp3+ regulatory t cell function
-
Wing K, Onishi Y, Prieto-Martin P, Yamaguchi T, Miyara M, Fehervari Z, et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science 2008;322:271-5.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
-
29
-
-
84949673235
-
Deletion of ctla-4 on regulatory t cells during adulthood leads to resistance to autoimmunity
-
Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, et al. Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity. J Exp Med 2015;212:1603-21.
-
(2015)
J Exp Med
, vol.212
, pp. 1603-1621
-
-
Paterson, A.M.1
Lovitch, S.B.2
Sage, P.T.3
Juneja, V.R.4
Lee, Y.5
Trombley, J.D.6
-
30
-
-
84991678476
-
An essential role for il-2 receptor in regulatory t cell function
-
in press
-
Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, et al.An essential role for IL-2 receptor in regulatory T cell function. Nat Immunol 2016; doi 10.1038/ni.3540, in press.
-
(2016)
Nat Immunol
-
-
Chinen, T.1
Kannan, A.K.2
Levine, A.G.3
Fan, X.4
Klein, U.5
Zheng, Y.6
-
31
-
-
84908123494
-
Continuous requirement for the tcr in regulatory t cell function
-
Levine AG, Arvey A, Jin W, Rudensky AY. Continuous requirement for the TCR in regulatory T cell function. Nat Immunol 2014;15: 1070-8.
-
(2014)
Nat Immunol
, vol.15
, pp. 1070-1078
-
-
Levine, A.G.1
Arvey, A.2
Jin, W.3
Rudensky, A.Y.4
-
32
-
-
84891590554
-
Regulatory t cells and natural killer t cells for modulation of gvhd following allogeneic hematopoietic cell transplantation
-
SchneidawindD, Pierini A,Negrin RS. Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation. Blood 2013;122:3116-21.
-
(2013)
Blood
, vol.122
, pp. 3116-3121
-
-
Schneidawind, D.1
Pierini, A.2
Negrin, R.S.3
-
33
-
-
0141461418
-
Cd4+cd25+ regulatory t cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bonemarrow transplantation
-
Edinger M, Hoffmann P, Ermann J, Drago K, Fathman CG, Strober S, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bonemarrow transplantation. Nat Med 2003;9:1144-50.
-
(2003)
Nat Med
, vol.9
, pp. 1144-1150
-
-
Edinger, M.1
Hoffmann, P.2
Ermann, J.3
Drago, K.4
Fathman, C.G.5
Strober, S.6
-
34
-
-
84892448554
-
Regulatory t cells in cancer immunotherapy
-
Nishikawa H, Sakaguchi S. Regulatory T cells in cancer immunotherapy. Curr Opin Immunol 2014;27:1-7.
-
(2014)
Curr Opin Immunol
, vol.27
, pp. 1-7
-
-
Nishikawa, H.1
Sakaguchi, S.2
|