메뉴 건너뛰기




Volumn 46, Issue 3, 2017, Pages 405-420

The Ubiquitin Binding Protein TAX1BP1 Mediates Autophagasome Induction and the Metabolic Transition of Activated T Cells

Author keywords

LC3; selective autophagy; ubiquitin

Indexed keywords

BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; UBIQUITIN BINDING PROTEIN TAX1BP1; UNCLASSIFIED DRUG; MTOR PROTEIN, MOUSE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; TAX1BP1 PROTEIN, MOUSE; TUMOR PROTEIN;

EID: 85015740864     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.02.018     Document Type: Article
Times cited : (55)

References (48)
  • 2
    • 0037662713 scopus 로고    scopus 로고
    • Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability
    • Beugnet, A., Tee, A.R., Taylor, P.M., Proud, C.G., Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability. Biochem. J. 372 (2003), 555–566.
    • (2003) Biochem. J. , vol.372 , pp. 555-566
    • Beugnet, A.1    Tee, A.R.2    Taylor, P.M.3    Proud, C.G.4
  • 3
    • 84883414890 scopus 로고    scopus 로고
    • The LIR motif - crucial for selective autophagy
    • Birgisdottir, Å.B., Lamark, T., Johansen, T., The LIR motif - crucial for selective autophagy. J. Cell Sci. 126 (2013), 3237–3247.
    • (2013) J. Cell Sci. , vol.126 , pp. 3237-3247
    • Birgisdottir, Å.B.1    Lamark, T.2    Johansen, T.3
  • 7
    • 0033595143 scopus 로고    scopus 로고
    • The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases
    • De Valck, D., Jin, D.-Y., Heyninck, K., Van de Craen, M., Contreras, R., Fiers, W., Jeang, K.-T., Beyaert, R., The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene 18 (1999), 4182–4190.
    • (1999) Oncogene , vol.18 , pp. 4182-4190
    • De Valck, D.1    Jin, D.-Y.2    Heyninck, K.3    Van de Craen, M.4    Contreras, R.5    Fiers, W.6    Jeang, K.-T.7    Beyaert, R.8
  • 8
    • 0024595926 scopus 로고
    • Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients
    • Eck, H.P., Gmünder, H., Hartmann, M., Petzoldt, D., Daniel, V., Dröge, W., Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients. Biol. Chem. Hoppe Seyler 370 (1989), 101–108.
    • (1989) Biol. Chem. Hoppe Seyler , vol.370 , pp. 101-108
    • Eck, H.P.1    Gmünder, H.2    Hartmann, M.3    Petzoldt, D.4    Daniel, V.5    Dröge, W.6
  • 9
    • 27744519400 scopus 로고    scopus 로고
    • Fuel feeds function: energy metabolism and the T-cell response
    • Fox, C.J., Hammerman, P.S., Thompson, C.B., Fuel feeds function: energy metabolism and the T-cell response. Nat. Rev. Immunol. 5 (2005), 844–852.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 844-852
    • Fox, C.J.1    Hammerman, P.S.2    Thompson, C.B.3
  • 10
    • 0031714559 scopus 로고    scopus 로고
    • CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter
    • Gachon, F., Peleraux, A., Thebault, S., Dick, J., Lemasson, I., Devaux, C., Mesnard, J.M., CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter. J. Virol. 72 (1998), 8332–8337.
    • (1998) J. Virol. , vol.72 , pp. 8332-8337
    • Gachon, F.1    Peleraux, A.2    Thebault, S.3    Dick, J.4    Lemasson, I.5    Devaux, C.6    Mesnard, J.M.7
  • 12
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras, A.C., Raught, B., Sonenberg, N., Regulation of translation initiation by FRAP/mTOR. Genes Dev. 15 (2001), 807–826.
    • (2001) Genes Dev. , vol.15 , pp. 807-826
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 13
    • 0025368350 scopus 로고
    • Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine
    • Gmünder, H., Eck, H.P., Benninghoff, B., Roth, S., Dröge, W., Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine. Cell. Immunol. 129 (1990), 32–46.
    • (1990) Cell. Immunol. , vol.129 , pp. 32-46
    • Gmünder, H.1    Eck, H.P.2    Benninghoff, B.3    Roth, S.4    Dröge, W.5
  • 14
    • 0025882811 scopus 로고
    • Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones
    • Gmünder, H., Eck, H.P., Dröge, W., Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones. Eur. J. Biochem. 201 (1991), 113–117.
    • (1991) Eur. J. Biochem. , vol.201 , pp. 113-117
    • Gmünder, H.1    Eck, H.P.2    Dröge, W.3
  • 15
    • 77649286736 scopus 로고    scopus 로고
    • Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E
    • Hsieh, A.C., Costa, M., Zollo, O., Davis, C., Feldman, M.E., Testa, J.R., Meyuhas, O., Shokat, K.M., Ruggero, D., Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell 17 (2010), 249–261.
    • (2010) Cancer Cell , vol.17 , pp. 249-261
    • Hsieh, A.C.1    Costa, M.2    Zollo, O.3    Davis, C.4    Feldman, M.E.5    Testa, J.R.6    Meyuhas, O.7    Shokat, K.M.8    Ruggero, D.9
  • 16
    • 78650643194 scopus 로고    scopus 로고
    • Macroautophagy regulates energy metabolism during effector T cell activation
    • Hubbard, V.M., Valdor, R., Patel, B., Singh, R., Cuervo, A.M., Macian, F., Macroautophagy regulates energy metabolism during effector T cell activation. J. Immunol. 185 (2010), 7349–7357.
    • (2010) J. Immunol. , vol.185 , pp. 7349-7357
    • Hubbard, V.M.1    Valdor, R.2    Patel, B.3    Singh, R.4    Cuervo, A.M.5    Macian, F.6
  • 18
    • 0036713778 scopus 로고    scopus 로고
    • TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
    • Inoki, K., Li, Y., Zhu, T., Wu, J., Guan, K.-L., TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4 (2002), 648–657.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 648-657
    • Inoki, K.1    Li, Y.2    Zhu, T.3    Wu, J.4    Guan, K.-L.5
  • 19
    • 0030754827 scopus 로고    scopus 로고
    • A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha
    • Jin, D.Y., Teramoto, H., Giam, C.Z., Chun, R.F., Gutkind, J.S., Jeang, K.T., A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha. J. Biol. Chem. 272 (1997), 25816–25823.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25816-25823
    • Jin, D.Y.1    Teramoto, H.2    Giam, C.Z.3    Chun, R.F.4    Gutkind, J.S.5    Jeang, K.T.6
  • 21
    • 0034662854 scopus 로고    scopus 로고
    • T6BP, a TRAF6-interacting protein involved in IL-1 signaling
    • Ling, L., Goeddel, D.V., T6BP, a TRAF6-interacting protein involved in IL-1 signaling. Proc. Natl. Acad. Sci. USA 97 (2000), 9567–9572.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9567-9572
    • Ling, L.1    Goeddel, D.V.2
  • 23
    • 54249141095 scopus 로고    scopus 로고
    • Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival
    • Maciver, N.J., Jacobs, S.R., Wieman, H.L., Wofford, J.A., Coloff, J.L., Rathmell, J.C., Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J. Leukoc. Biol. 84 (2008), 949–957.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 949-957
    • Maciver, N.J.1    Jacobs, S.R.2    Wieman, H.L.3    Wofford, J.A.4    Coloff, J.L.5    Rathmell, J.C.6
  • 25
    • 0036342294 scopus 로고    scopus 로고
    • Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
    • Manning, B.D., Tee, A.R., Logsdon, M.N., Blenis, J., Cantley, L.C., Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol. Cell 10 (2002), 151–162.
    • (2002) Mol. Cell , vol.10 , pp. 151-162
    • Manning, B.D.1    Tee, A.R.2    Logsdon, M.N.3    Blenis, J.4    Cantley, L.C.5
  • 26
    • 33747624440 scopus 로고    scopus 로고
    • The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation
    • Martin, P., Diaz-Meco, M.T., Moscat, J., The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation. EMBO J. 25 (2006), 3524–3533.
    • (2006) EMBO J. , vol.25 , pp. 3524-3533
    • Martin, P.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 28
    • 85025352713 scopus 로고
    • Rapamycins: Antifungal, antitumor, antiproliferative, and immunosuppressive macrolides
    • Morris, R.E., Rapamycins: Antifungal, antitumor, antiproliferative, and immunosuppressive macrolides. Transplant. Rev. 6 (1992), 39–87.
    • (1992) Transplant. Rev. , vol.6 , pp. 39-87
    • Morris, R.E.1
  • 30
    • 84870527124 scopus 로고    scopus 로고
    • TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling
    • Newman, A.C., Scholefield, C.L., Kemp, A.J., Newman, M., McIver, E.G., Kamal, A., Wilkinson, S., TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-κB signalling. PLoS ONE, 7, 2012, e50672.
    • (2012) PLoS ONE , vol.7 , pp. e50672
    • Newman, A.C.1    Scholefield, C.L.2    Kemp, A.J.3    Newman, M.4    McIver, E.G.5    Kamal, A.6    Wilkinson, S.7
  • 31
    • 0031455258 scopus 로고    scopus 로고
    • The amino acid composition of mammalian and bacterial cells
    • Okayasu, T., Ikeda, M., Akimoto, K., Sorimachi, K., The amino acid composition of mammalian and bacterial cells. Amino Acids 13 (1997), 379–391.
    • (1997) Amino Acids , vol.13 , pp. 379-391
    • Okayasu, T.1    Ikeda, M.2    Akimoto, K.3    Sorimachi, K.4
  • 32
    • 84885670616 scopus 로고    scopus 로고
    • Fueling immunity: insights into metabolism and lymphocyte function
    • Pearce, E.L., Poffenberger, M.C., Chang, C.-H., Jones, R.G., Fueling immunity: insights into metabolism and lymphocyte function. Science, 342, 2013, 1242454.
    • (2013) Science , vol.342 , pp. 1242454
    • Pearce, E.L.1    Poffenberger, M.C.2    Chang, C.-H.3    Jones, R.G.4
  • 33
    • 84903277871 scopus 로고    scopus 로고
    • Integrating canonical and metabolic signalling programmes in the regulation of T cell responses
    • Pollizzi, K.N., Powell, J.D., Integrating canonical and metabolic signalling programmes in the regulation of T cell responses. Nat. Rev. Immunol. 14 (2014), 435–446.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 435-446
    • Pollizzi, K.N.1    Powell, J.D.2
  • 35
    • 33846461678 scopus 로고    scopus 로고
    • A critical role for the autophagy gene Atg5 in T cell survival and proliferation
    • Pua, H.H., Dzhagalov, I., Chuck, M., Mizushima, N., He, Y.W., A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J. Exp. Med. 204 (2007), 25–31.
    • (2007) J. Exp. Med. , vol.204 , pp. 25-31
    • Pua, H.H.1    Dzhagalov, I.2    Chuck, M.3    Mizushima, N.4    He, Y.W.5
  • 36
  • 37
    • 84996635723 scopus 로고    scopus 로고
    • HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains
    • Ren, T., Takahashi, Y., Liu, X., Loughran, T.P., Sun, S.C., Wang, H.-G., Cheng, H., HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains. Oncogene 34 (2015), 334–345.
    • (2015) Oncogene , vol.34 , pp. 334-345
    • Ren, T.1    Takahashi, Y.2    Liu, X.3    Loughran, T.P.4    Sun, S.C.5    Wang, H.-G.6    Cheng, H.7
  • 38
    • 84892859905 scopus 로고    scopus 로고
    • Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
    • Rogov, V., Dötsch, V., Johansen, T., Kirkin, V., Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol. Cell 53 (2014), 167–178.
    • (2014) Mol. Cell , vol.53 , pp. 167-178
    • Rogov, V.1    Dötsch, V.2    Johansen, T.3    Kirkin, V.4
  • 39
    • 0018254443 scopus 로고
    • Determination of cysteine in plasma and urine and homocysteine in plasma by high-pressure liquid chromatography
    • Saetre, R., Rabenstein, D.L., Determination of cysteine in plasma and urine and homocysteine in plasma by high-pressure liquid chromatography. Anal. Biochem. 90 (1978), 684–692.
    • (1978) Anal. Biochem. , vol.90 , pp. 684-692
    • Saetre, R.1    Rabenstein, D.L.2
  • 40
    • 84958641630 scopus 로고    scopus 로고
    • Mechanistic target of rapamycin complex 1/S6 kinase 1 signals influence T cell activation independently of ribosomal protein S6 phosphorylation
    • Salmond, R.J., Brownlie, R.J., Meyuhas, O., Zamoyska, R., Mechanistic target of rapamycin complex 1/S6 kinase 1 signals influence T cell activation independently of ribosomal protein S6 phosphorylation. J. Immunol. 195 (2015), 4615–4622.
    • (2015) J. Immunol. , vol.195 , pp. 4615-4622
    • Salmond, R.J.1    Brownlie, R.J.2    Meyuhas, O.3    Zamoyska, R.4
  • 41
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov, D.D., Guertin, D.A., Ali, S.M., Sabatini, D.M., Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307 (2005), 1098–1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 42
    • 34548405689 scopus 로고    scopus 로고
    • Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling
    • Shembade, N., Harhaj, N.S., Liebl, D.J., Harhaj, E.W., Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling. EMBO J. 26 (2007), 3910–3922.
    • (2007) EMBO J. , vol.26 , pp. 3910-3922
    • Shembade, N.1    Harhaj, N.S.2    Liebl, D.J.3    Harhaj, E.W.4
  • 43
    • 0033534734 scopus 로고    scopus 로고
    • Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells
    • Shigemitsu, K., Tsujishita, Y., Hara, K., Nanahoshi, M., Avruch, J., Yonezawa, K., Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J. Biol. Chem. 274 (1999), 1058–1065.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1058-1065
    • Shigemitsu, K.1    Tsujishita, Y.2    Hara, K.3    Nanahoshi, M.4    Avruch, J.5    Yonezawa, K.6
  • 44
    • 84868148725 scopus 로고    scopus 로고
    • Failure of amino acid homeostasis causes cell death following proteasome inhibition
    • Suraweera, A., Münch, C., Hanssum, A., Bertolotti, A., Failure of amino acid homeostasis causes cell death following proteasome inhibition. Mol. Cell 48 (2012), 242–253.
    • (2012) Mol. Cell , vol.48 , pp. 242-253
    • Suraweera, A.1    Münch, C.2    Hanssum, A.3    Bertolotti, A.4
  • 45
    • 84867103427 scopus 로고    scopus 로고
    • Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome
    • Tumbarello, D.A., Waxse, B.J., Arden, S.D., Bright, N.A., Kendrick-Jones, J., Buss, F., Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. Nat. Cell Biol. 14 (2012), 1024–1035.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 1024-1035
    • Tumbarello, D.A.1    Waxse, B.J.2    Arden, S.D.3    Bright, N.A.4    Kendrick-Jones, J.5    Buss, F.6
  • 46
    • 84946085716 scopus 로고    scopus 로고
    • The autophagy receptor TAX1BP1 and the molecular motor myosin VI are required for clearance of Salmonella typhimurium by autophagy
    • Tumbarello, D.A., Manna, P.T., Allen, M., Bycroft, M., Arden, S.D., Kendrick-Jones, J., Buss, F., The autophagy receptor TAX1BP1 and the molecular motor myosin VI are required for clearance of Salmonella typhimurium by autophagy. PLoS Pathog., 11, 2015, e1005174.
    • (2015) PLoS Pathog. , vol.11 , pp. e1005174
    • Tumbarello, D.A.1    Manna, P.T.2    Allen, M.3    Bycroft, M.4    Arden, S.D.5    Kendrick-Jones, J.6    Buss, F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.