In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development

Development (Cambridge)

Volumn 144, Issue 6, 2017, Pages 1045-1055

  Tsai, Yu Hwai ^a   Nattiv, Roy ^b,c   Dedhia, Priya H ^a   Nagy, Melinda S ^a   Chin, Alana M ^a   Thomson, Matthew ^c   Klein, Ophir D ^b,c   Spence, Jason R ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Human; Intestine; Organoid; Patterning; Pluripotent stem cells

Indexed keywords

6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; FIBROBLAST GROWTH FACTOR 4; WNT PROTEIN; BIOLOGICAL MARKER; FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ARTICLE; CYTOPLASM; DUODENUM; FETUS; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; HUMAN DEVELOPMENT; HUMAN TISSUE; ILEUM; IN VITRO STUDY; IN VIVO STUDY; INTESTINAL STEM CELL; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; TRANSLATIONAL RESEARCH; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGY; CELL DIFFERENTIATION; CYTOLOGY; EMBRYO DEVELOPMENT; EMBRYOLOGY; GENE EXPRESSION PROFILING; GENETICS; INTESTINE; METABOLISM; MORPHOGENESIS; REPRODUCIBILITY; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TRANSPLANTATION;

ANIMALS; BIOMARKERS; BODY PATTERNING; CELL DIFFERENTIATION; COMPUTATIONAL BIOLOGY; EMBRYONIC DEVELOPMENT; FETUS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION PROFILING; HUMANS; INTESTINES; MICE; ORGANOIDS; PLURIPOTENT STEM CELLS; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 85015303065     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.138453     Document Type: Article

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