Different activities of the Frizzled-related proteins frzb2 and sizzled2 during Xenopus anteroposterior patterning

Developmental Biology

Volumn 227, Issue 1, 2000, Pages 118-132

  Bradley, Leila ^a   Sun, Benjamin ^a   Collins Racie, Lisa ^b   LaVallie, Ed ^b   McCoy, John ^b   Sive, Hazel ^a  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b PFIZER INC   (United States)

Author keywords

Anterior; Cement gland; Frzb; Patterning; Secreted factors; Wnt; Xenopus

Indexed keywords

ARTICLE; CONTROLLED STUDY; ECTODERM; EMBRYO; GENE ACTIVITY; GENE EXPRESSION; MESODERM; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; XENOPUS;

INVERTEBRATA; XENOPUS;

EID: 0034329498     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9873     Document Type: Article

References (68)

1. Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation
2. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
3. Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development
4. A new member of the frizzled family from Drosophila function as a wingless receptor
5. Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos
6. Vertebrate head induction by anterior primitive endoderm
7. The structure and expression of the Xenopus Krox-20 gene: Conserved and divergent patterns of expression in rhombomeres and neural crest
8. Positive and negative signals modulate formation of the Xenopus cement gland
9. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
10. Isolation of cDNAs partially encoding four Xenopus Wnt-1/Int-1-related proteins and characterization of their transient expression during embryonic development
11. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus
12. Posterior expression of a homeobox gene in early Xenopus embryos
13. Xwnt-8b: A maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis
14. Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis
15. Control of neural crest cell fate by the Wnt signalling pathway
16. Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos
17. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain
18. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms
19. Identification of otx2 target genes and restrictions in ectodermal competence during Xenopus cement gland formation
20. Vertebrate anteroposterior patterning: The Xenopus neurectoderm as a paradigm
21. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
22. Head induction by simultaneous repression of BMP and Wnt signalling in Xenopus
23. In situ hybridization: An improved whole-mount method for Xenopus embryos
24. Expression of an engrailed-related protein in the anterior neural ectoderm of early Xenopus embryos
25. Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos
26. A new secreted protein that binds to Wnt proteins and inhibits their activities
27. A role for Xenopus Frizzled 8 in dorsal development
28. Specific modulation of ectodermal cell fates in Xenopus embryos by glycogen synthase kinase
29. A genetic selection for isolating cDNAs encoding secreted proteins
30. Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm
31. The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture
32. Regulation of the Xenopus labial homeodomain genes, HoxA1 and HoxD1: Activation by retinoids and peptide growth factors
33. An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs
34. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
35. Xwnt-11: A maternally expressed Xenopus wnt gene
36. Neural crest induction in Xenopus: Evidence for a two-signal model
37. Xwnt-2b is a novel axis-inducing Xenopus Wnt, which is expressed in embryonic brain
38. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
39. The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling
40. Specification of the anteroposterior neural axis through synergistic interaction of the Wnt signaling cascade with noggin and follistatin
41. An amphibian cytoskeletal-type actin gene is expressed exclusively in muscle tissue
42. In pursuit of the functions of the Wnt family of developmental regulators: Insights from Xenopus laevis
43. Xwnt-5A: A maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
44. Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing
45. Localization of a nervous system specific class II beta tubulin gene in Xenopus laevis embryos by whole mount in situ hybridisation
46. Crescent, a novel chick gene encoding a Frizzled-like cysteine-rich domain, is expressed in anterior regions during early embryogenesis
47. Overexpression of Xgsk-3 disrupts anterior ectodermal patterning in Xenopus
48. Evidence for non-axial A/P patterning in the nonneural ectoderm of Xenopus and zebra fish pregastrula embryos
49. Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction
50. Anteroposterior patterning in the zebrafish, Danio rerio: An explant assay reveals inductive and suppressive cell interactions
51. Sizzled: A secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos
52. Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
53. Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system
54. Progressive determination during formation of the anteroposterior axis in Xenopus laevis
55. A sticky problem: The Xenopus cement gland as a paradigm for anteroposterior patterning
56. Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis
57. Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center
58. Transcription factor AP-2 is tissue-specific in Xenopus and is closely related or identical to keratin transcription factor 1 (KTF-1)
59. Derriere: A TGF-beta family member required for posterior development in Xenopus
60. Wnt-3a regulates somite and tailbud formation in the mouse embryo
61. Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8
62. Two novel Xenopus frizzled genes expressed in developing heart and brain
63. The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons
64. Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist
65. Direct and long-range action of a wingless morphogen gradient
66. An indelible lineage marker for Xenopus using a mutated green fluorescent protein