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Volumn 129, Issue 6, 2017, Pages 704-714

Myeloid neoplasms with eosinophilia

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; JANUS KINASE 2; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TRANSCRIPTION FACTOR ETV6; ABELSON KINASE; ANTINEOPLASTIC AGENT; FGFR1 PROTEIN, HUMAN; FLT3 PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; ONCOPROTEIN; PDGFRB PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

EID: 85015294920     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-10-695973     Document Type: Review
Times cited : (196)

References (103)
  • 1
    • 84865701899 scopus 로고    scopus 로고
    • Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes
    • Valent P, Klion AD, Horny HP, et al. Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. J Allergy Clin Immunol. 2012; 130(3): 607-612.
    • (2012) J Allergy Clin Immunol. , vol.130 , Issue.3 , pp. 607-612
    • Valent, P.1    Klion, A.D.2    Horny, H.P.3
  • 2
    • 0014299959 scopus 로고
    • The hypereosinophilic syndromes
    • Hardy WR, Anderson RE. The hypereosinophilic syndromes. Ann Intern Med. 1968;68(6): 1220-1229.
    • (1968) Ann Intern Med. , vol.68 , Issue.6 , pp. 1220-1229
    • Hardy, W.R.1    Anderson, R.E.2
  • 3
    • 0016430025 scopus 로고
    • The hypereosinophilic syndrome: Analysis of fourteen cases with review of the literature
    • Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore). 1975;54(1): 1-27.
    • (1975) Medicine (Baltimore). , vol.54 , Issue.1 , pp. 1-27
    • Chusid, M.J.1    Dale, D.C.2    West, B.C.3    Wolff, S.M.4
  • 4
    • 0032574902 scopus 로고    scopus 로고
    • Eosinophilia
    • Rothenberg ME. Eosinophilia. N Engl J Med. 1998;338(22): 1592-1600.
    • (1998) N Engl J Med. , vol.338 , Issue.22 , pp. 1592-1600
    • Rothenberg, M.E.1
  • 5
    • 84863805992 scopus 로고    scopus 로고
    • Pathogenesis and classification of eosinophil disorders: A review of recent developments in the field
    • Valent P, Gleich GJ, Reiter A, et al. Pathogenesis and classification of eosinophil disorders: a review of recent developments in the field. Expert Rev Hematol. 2012;5(2): 157-176.
    • (2012) Expert Rev Hematol. , vol.5 , Issue.2 , pp. 157-176
    • Valent, P.1    Gleich, G.J.2    Reiter, A.3
  • 6
    • 75749119699 scopus 로고    scopus 로고
    • Hypereosinophilic syndrome and clonal eosinophilia: Point-of-care diagnostic algorithm and treatment update
    • Tefferi A, Gotlib J, Pardanani A. Hypereosinophilic syndrome and clonal eosinophilia: point-of-care diagnostic algorithm and treatment update. Mayo Clin Proc. 2010; 85(2): 158-164.
    • (2010) Mayo Clin Proc. , vol.85 , Issue.2 , pp. 158-164
    • Tefferi, A.1    Gotlib, J.2    Pardanani, A.3
  • 7
    • 0027958133 scopus 로고
    • Brief report: Clonal proliferation of type 2 helper t cells in a man with the hypereosinophilic syndrome
    • Cogan E, Schandené L, Crusiaux A, Cochaux P, Velu T, Goldman M. Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome. N Engl J Med. 1994;330(8): 535-538.
    • (1994) N Engl J Med. , vol.330 , Issue.8 , pp. 535-538
    • Cogan, E.1    Schandené, L.2    Crusiaux, A.3    Cochaux, P.4    Velu, T.5    Goldman, M.6
  • 8
    • 0344809973 scopus 로고    scopus 로고
    • Abnormal clones of t cells producing interleukin-5 in idiopathic eosinophilia
    • Simon HU, Plötz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin-5 in idiopathic eosinophilia. N Engl J Med. 1999; 341(15): 1112-1120.
    • (1999) N Engl J Med. , vol.341 , Issue.15 , pp. 1112-1120
    • Simon, H.U.1    Plötz, S.G.2    Dummer, R.3    Blaser, K.4
  • 10
    • 84974560145 scopus 로고    scopus 로고
    • The 2016 revision to the world health organization classification of myeloid neoplasms and acute leukemia
    • Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20): 2391-2405.
    • (2016) Blood. , vol.127 , Issue.20 , pp. 2391-2405
    • Arber, D.A.1    Orazi, A.2    Hasserjian, R.3
  • 12
    • 84959498230 scopus 로고    scopus 로고
    • Diagnostic challenges in the work up of hypereosinophilia: Pitfalls in bone marrow core biopsy interpretation
    • Schwaab J, Jawhar M, Naumann N, et al. Diagnostic challenges in the work up of hypereosinophilia: pitfalls in bone marrow core biopsy interpretation. Ann Hematol. 2016;95(4): 557-562.
    • (2016) Ann Hematol. , vol.95 , Issue.4 , pp. 557-562
    • Schwaab, J.1    Jawhar, M.2    Naumann, N.3
  • 13
    • 0038792233 scopus 로고    scopus 로고
    • Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness
    • Klion AD, Noel P, Akin C, et al. Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness. Blood. 2003;101(12): 4660-4666.
    • (2003) Blood. , vol.101 , Issue.12 , pp. 4660-4666
    • Klion, A.D.1    Noel, P.2    Akin, C.3
  • 14
    • 8644263305 scopus 로고    scopus 로고
    • Fip1l1-pdgfra fusion: Prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia
    • Pardanani A, Brockman SR, Paternoster SF, et al. FIP1L1-PDGFRA fusion: prevalence and clinicopathologic correlates in 89 consecutive patients with moderate to severe eosinophilia. Blood. 2004;104(10): 3038-3045.
    • (2004) Blood. , vol.104 , Issue.10 , pp. 3038-3045
    • Pardanani, A.1    Brockman, S.R.2    Paternoster, S.F.3
  • 15
    • 34548272148 scopus 로고    scopus 로고
    • Kit d816vassociated systemic mastocytosis with eosinophilia and fip1l1/pdgfra-Associated chronic eosinophilic leukemia are distinct entities
    • Maric I, Robyn J, Metcalfe DD, et al. KIT D816Vassociated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-Associated chronic eosinophilic leukemia are distinct entities. J Allergy Clin Immunol. 2007;120(3): 680-687.
    • (2007) J Allergy Clin Immunol. , vol.120 , Issue.3 , pp. 680-687
    • Maric, I.1    Robyn, J.2    Metcalfe, D.D.3
  • 16
    • 84939512552 scopus 로고    scopus 로고
    • Kit d816v and jak2 v617f mutations are seen recurrently in hypereosinophilia of unknown significance
    • Schwaab J, Umbach R, Metzgeroth G, et al. KIT D816V and JAK2 V617F mutations are seen recurrently in hypereosinophilia of unknown significance. Am J Hematol. 2015;90(9): 774-777.
    • (2015) Am J Hematol. , vol.90 , Issue.9 , pp. 774-777
    • Schwaab, J.1    Umbach, R.2    Metzgeroth, G.3
  • 17
    • 0038341142 scopus 로고    scopus 로고
    • Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia
    • Pardanani A, Reeder T, Li CY, Tefferi A. Eosinophils are derived from the neoplastic clone in patients with systemic mastocytosis and eosinophilia. Leuk Res. 2003;27(10): 883-885.
    • (2003) Leuk Res. , vol.27 , Issue.10 , pp. 883-885
    • Pardanani, A.1    Reeder, T.2    Li, C.Y.3    Tefferi, A.4
  • 18
    • 33749368009 scopus 로고    scopus 로고
    • Kit mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: A prospective study of the Spanish network on mastocytosis (rema) in a series of 113 patients
    • Garcia-Montero AC, Jara-Acevedo M, Teodosio C, et al. KIT mutation in mast cells and other bone marrow hematopoietic cell lineages in systemic mast cell disorders: a prospective study of the Spanish Network on Mastocytosis (REMA) in a series of 113 patients. Blood. 2006;108(7): 2366-2372.
    • (2006) Blood. , vol.108 , Issue.7 , pp. 2366-2372
    • Garcia-Montero, A.C.1    Jara-Acevedo, M.2    Teodosio, C.3
  • 19
    • 84927776342 scopus 로고    scopus 로고
    • Novel recurrent mutations in ethanolamine kinase 1 (etnk1) gene in systemic mastocytosis with eosinophilia and chronic myelomonocytic leukemia
    • Lasho TL, Finke CM, Zblewski D, et al. Novel recurrent mutations in ethanolamine kinase 1 (ETNK1) gene in systemic mastocytosis with eosinophilia and chronic myelomonocytic leukemia. Blood Cancer J. 2015;5: e275.
    • (2015) Blood Cancer J. , vol.5 , pp. e275
    • Lasho, T.L.1    Finke, C.M.2    Zblewski, D.3
  • 20
    • 0035823530 scopus 로고    scopus 로고
    • Case report: Rapid and complete control of idiopathic hypereosinophilia with imatinib mesylate
    • Schaller JL, Burkland GA. Case report: rapid and complete control of idiopathic hypereosinophilia with imatinib mesylate. MedGenMed. 2001; 3(5): 9.
    • (2001) MedGenMed. , vol.3 , Issue.5 , pp. 9
    • Schaller, J.L.1    Burkland, G.A.2
  • 22
    • 0036063077 scopus 로고    scopus 로고
    • Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate
    • Ault P, Cortes J, Koller C, Kaled ES, Kantarjian H. Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate. Leuk Res. 2002;26(9): 881-884.
    • (2002) Leuk Res. , vol.26 , Issue.9 , pp. 881-884
    • Ault, P.1    Cortes, J.2    Koller, C.3    Kaled, E.S.4    Kantarjian, H.5
  • 23
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the pdgfra and fip1l1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • Cools J, DeAngelo DJ, Gotlib J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med. 2003;348(13): 1201-1214.
    • (2003) N Engl J Med. , vol.348 , Issue.13 , pp. 1201-1214
    • Cools, J.1    DeAngelo, D.J.2    Gotlib, J.3
  • 24
  • 25
    • 10744228486 scopus 로고    scopus 로고
    • Chic2 deletion, a surrogate for fip1l1-pdgfra fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy
    • Pardanani A, Ketterling RP, Brockman SR, et al. CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapy. Blood. 2003;102(9): 3093-3096.
    • (2003) Blood. , vol.102 , Issue.9 , pp. 3093-3096
    • Pardanani, A.1    Ketterling, R.P.2    Brockman, S.R.3
  • 26
    • 34548148179 scopus 로고    scopus 로고
    • A case of fip1l1-pdgfra-positive chronic eosinophilic leukemia with a rare fip1l1 breakpoint
    • Lambert F, Heimann P, Herens C, Chariot A, Bours V. A case of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia with a rare FIP1L1 breakpoint. J Mol Diagn. 2007;9(3): 414-419.
    • (2007) J Mol Diagn. , vol.9 , Issue.3 , pp. 414-419
    • Lambert, F.1    Heimann, P.2    Herens, C.3    Chariot, A.4    Bours, V.5
  • 27
    • 34249742721 scopus 로고    scopus 로고
    • Recurrent finding of the fip1l1-pdgfra fusion gene in eosinophilia-Associated acute myeloid leukemia and lymphoblastic t-cell lymphoma
    • Metzgeroth G, Walz C, Score J, et al. Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-Associated acute myeloid leukemia and lymphoblastic T-cell lymphoma. Leukemia. 2007;21(6): 1183-1188.
    • (2007) Leukemia. , vol.21 , Issue.6 , pp. 1183-1188
    • Metzgeroth, G.1    Walz, C.2    Score, J.3
  • 28
    • 79953091929 scopus 로고    scopus 로고
    • Novel imatinibsensitive pdgfra-Activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease
    • Elling C, Erben P, Walz C, et al. Novel imatinibsensitive PDGFRA-Activating point mutations in hypereosinophilic syndrome induce growth factor independence and leukemia-like disease. Blood. 2011;117(10): 2935-2943.
    • (2011) Blood. , vol.117 , Issue.10 , pp. 2935-2943
    • Elling, C.1    Erben, P.2    Walz, C.3
  • 29
    • 34249732053 scopus 로고    scopus 로고
    • Lowdose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in fip1l1-pdgfra-positive chronic eosinophilic leukemia
    • Jovanovic JV, Score J, Waghorn K, et al. Lowdose imatinib mesylate leads to rapid induction of major molecular responses and achievement of complete molecular remission in FIP1L1-PDGFRA-positive chronic eosinophilic leukemia. Blood. 2007;109(11): 4635-4640.
    • (2007) Blood. , vol.109 , Issue.11 , pp. 4635-4640
    • Jovanovic, J.V.1    Score, J.2    Waghorn, K.3
  • 30
    • 35348993411 scopus 로고    scopus 로고
    • The efficacy of imatinib mesylate in patients with fip1l1-pdgfralpha-positive hypereosinophilic syndrome. Results of a multicenter prospective study
    • Baccarani M, Cilloni D, Rondoni M, et al. The efficacy of imatinib mesylate in patients with FIP1L1-PDGFRalpha-positive hypereosinophilic syndrome. Results of a multicenter prospective study. Haematologica. 2007;92(9): 1173-1179.
    • (2007) Haematologica. , vol.92 , Issue.9 , pp. 1173-1179
    • Baccarani, M.1    Cilloni, D.2    Rondoni, M.3
  • 31
    • 0942276859 scopus 로고    scopus 로고
    • Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome
    • Klion AD, Robyn J, Akin C, et al. Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Blood. 2004; 103(2): 473-478.
    • (2004) Blood. , vol.103 , Issue.2 , pp. 473-478
    • Klion, A.D.1    Robyn, J.2    Akin, C.3
  • 32
    • 71249101922 scopus 로고    scopus 로고
    • Hypereosinophilic syndrome: A multicenter, retrospective analysis of clinical characteristics and response to therapy
    • Ogbogu PU, Bochner BS, Butterfield JH, et al. Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol. 2009;124(6): 1319-1325.
    • (2009) J Allergy Clin Immunol. , vol.124 , Issue.6 , pp. 1319-1325
    • Ogbogu, P.U.1    Bochner, B.S.2    Butterfield, J.H.3
  • 33
    • 77953258448 scopus 로고    scopus 로고
    • Clinical characteristics of patients with chronic eosinophilic leukaemia (cel) harbouring fip1l1-pdgfra fusion transcript-results of polish multicentre study
    • Helbig G, Moskwa A, Hus M, et al. Clinical characteristics of patients with chronic eosinophilic leukaemia (CEL) harbouring FIP1L1-PDGFRA fusion transcript-results of Polish multicentre study. Hematol Oncol. 2010; 28(2): 93-97.
    • (2010) Hematol Oncol. , vol.28 , Issue.2 , pp. 93-97
    • Helbig, G.1    Moskwa, A.2    Hus, M.3
  • 34
    • 84869096442 scopus 로고    scopus 로고
    • Long-Term follow-up of fip1l1-pdgfra-mutated patients with eosinophilia: Survival and clinical outcome
    • Pardanani A, D'Souza A, Knudson RA, Hanson CA, Ketterling RP, Tefferi A. Long-Term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome. Leukemia. 2012;26(11): 2439-2441.
    • (2012) Leukemia. , vol.26 , Issue.11 , pp. 2439-2441
    • Pardanani, A.1    D'Souza, A.2    Knudson, R.A.3    Hanson, C.A.4    Ketterling, R.P.5    Tefferi, A.6
  • 35
    • 84887988208 scopus 로고    scopus 로고
    • The spectrum of fip1l1-pdgfra-Associated chronic eosinophilic leukemia: New insights based on a survey of 44 cases
    • Legrand F, Renneville A, Macintyre E, et al; on behalf of the French Eosinophil Network. The spectrum of FIP1L1-PDGFRA-Associated chronic eosinophilic leukemia: new insights based on a survey of 44 cases. Medicine (Baltimore). 2013;92(5): e1-e9.
    • (2013) Medicine (Baltimore) , vol.92 , Issue.5 , pp. e1-e9
    • Legrand, F.1    Renneville, A.2    Macintyre, E.3
  • 36
    • 40949147830 scopus 로고    scopus 로고
    • A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in fip1l1-pdgfraexpressing patients
    • Helbig G, Stella-Holowiecka B, Majewski M, et al. A single weekly dose of imatinib is sufficient to induce and maintain remission of chronic eosinophilic leukaemia in FIP1L1-PDGFRAexpressing patients. Br J Haematol. 2008; 141(2): 200-204.
    • (2008) Br J Haematol. , vol.141 , Issue.2 , pp. 200-204
    • Helbig, G.1    Stella-Holowiecka, B.2    Majewski, M.3
  • 37
    • 36348993783 scopus 로고    scopus 로고
    • Relapse following discontinuation of imatinib mesylate therapy for fip1l1/pdgfra-positive chronic eosinophilic leukemia: Implications for optimal dosing
    • Klion AD, Robyn J, Maric I, et al. Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing. Blood. 2007;110(10): 3552-3556.
    • (2007) Blood. , vol.110 , Issue.10 , pp. 3552-3556
    • Klion, A.D.1    Robyn, J.2    Maric, I.3
  • 38
    • 84892874629 scopus 로고    scopus 로고
    • Cessation of imatinib mesylate may lead to sustained hematologic and molecular remission in fip1l1-pdgfra-mutated hypereosinophilic syndrome
    • Helbig G, Kyrcz-Krzemién S. Cessation of imatinib mesylate may lead to sustained hematologic and molecular remission in FIP1L1-PDGFRA-mutated hypereosinophilic syndrome. Am J Hematol. 2014;89(1): 115.
    • (2014) Am J Hematol. , vol.89 , Issue.1 , pp. 115
    • Helbig, G.1    Kyrcz-Krzemién, S.2
  • 39
    • 13544267772 scopus 로고    scopus 로고
    • Myeloid blast crisis evolving during imatinib treatment of an fip1l1-pdgfr alpha-positive chronic myeloproliferative disease with prominent eosinophilia
    • von Bubnoff N, Sandherr M, Schlimok G, Andreesen R, Peschel C, Duyster J. Myeloid blast crisis evolving during imatinib treatment of an FIP1L1-PDGFR alpha-positive chronic myeloproliferative disease with prominent eosinophilia. Leukemia. 2005;19(2): 286-287.
    • (2005) Leukemia. , vol.19 , Issue.2 , pp. 286-287
    • Von Bubnoff, N.1    Sandherr, M.2    Schlimok, G.3    Andreesen, R.4    Peschel, C.5    Duyster, J.6
  • 40
    • 33746473457 scopus 로고    scopus 로고
    • Chronic eosinophilic leukaemia with fip1l1-pdgfra fusion and t6741 mutation that evolved from langerhans cell histiocytosis with eosinophilia after chemotherapy
    • Ohnishi H, Kandabashi K, Maeda Y, Kawamura M, Watanabe T. Chronic eosinophilic leukaemia with FIP1L1-PDGFRA fusion and T6741 mutation that evolved from Langerhans cell histiocytosis with eosinophilia after chemotherapy. Br J Haematol. 2006;134(5): 547-549.
    • (2006) Br J Haematol. , vol.134 , Issue.5 , pp. 547-549
    • Ohnishi, H.1    Kandabashi, K.2    Maeda, Y.3    Kawamura, M.4    Watanabe, T.5
  • 41
    • 66849087150 scopus 로고    scopus 로고
    • Fip1l1-pdgfralpha d842v, a novel panresistant mutant, emerging after treatment of fip1l1-pdgfralpha t674i eosinophilic leukemia with single agent sorafenib
    • Lierman E, Michaux L, Beullens E, et al. FIP1L1-PDGFRalpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRalpha T674I eosinophilic leukemia with single agent sorafenib. Leukemia. 2009;23(5): 845-851.
    • (2009) Leukemia. , vol.23 , Issue.5 , pp. 845-851
    • Lierman, E.1    Michaux, L.2    Beullens, E.3
  • 42
    • 33749325184 scopus 로고    scopus 로고
    • Comparison of imatinib mesylate, dasatinib (bms-354825), and nilotinib (amn107) in an n-ethyl-n-nitrosourea (enu)-based mutagenesis screen: High efficacy of drug combinations
    • Bradeen HA, Eide CA, O'Hare T, et al. Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations. Blood. 2006;108(7): 2332-2338.
    • (2006) Blood. , vol.108 , Issue.7 , pp. 2332-2338
    • Bradeen, H.A.1    Eide, C.A.2    O'Hare, T.3
  • 43
    • 0142119964 scopus 로고    scopus 로고
    • Pkc412 overcomes resistance to imatinib in a murine model of fip1l1-pdgfra-induced myeloproliferative disease
    • Cools J, Stover EH, Boulton CL, et al. PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRa-induced myeloproliferative disease. Cancer Cell. 2003; 3(5): 459-469.
    • (2003) Cancer Cell. , vol.3 , Issue.5 , pp. 459-469
    • Cools, J.1    Stover, E.H.2    Boulton, C.L.3
  • 44
    • 33747203008 scopus 로고    scopus 로고
    • Sorafenib is a potent inhibitor of fip1l1-pdgfralpha and the imatinib-resistant fip1l1-pdgfralpha t674i mutant
    • Lierman E, Folens C, Stover EH, et al. Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant. Blood. 2006;108(4): 1374-1376.
    • (2006) Blood. , vol.108 , Issue.4 , pp. 1374-1376
    • Lierman, E.1    Folens, C.2    Stover, E.H.3
  • 45
    • 27144551665 scopus 로고    scopus 로고
    • The small molecule tyrosine kinase inhibitor amn107 inhibits tel-pdgfrbeta and fip1l1-pdgfralpha in vitro and in vivo
    • Stover EH, Chen J, Lee BH, et al. The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo. Blood. 2005; 106(9): 3206-3213.
    • (2005) Blood. , vol.106 , Issue.9 , pp. 3206-3213
    • Stover, E.H.1    Chen, J.2    Lee, B.H.3
  • 46
    • 33745059630 scopus 로고    scopus 로고
    • The fip1l1-pdgfra t674i mutation can be inhibited by the tyrosine kinase inhibitor amn107 (nilotinib)
    • von Bubnoff N, Gorantla SP, Thöne S, Peschel C, Duyster J. The FIP1L1-PDGFRA T674I mutation can be inhibited by the tyrosine kinase inhibitor AMN107 (nilotinib). Blood. 2006; 107(12): 4970-4971.
    • (2006) Blood. , vol.107 , Issue.12 , pp. 4970-4971
    • Von Bubnoff, N.1    Gorantla, S.P.2    Thöne, S.3    Peschel, C.4    Duyster, J.5
  • 47
    • 84856759425 scopus 로고    scopus 로고
    • Limited clinical activity of nilotinib and sorafenib in fip1l1-pdgfra positive chronic eosinophilic leukemia with imatinib-resistant t674i mutation
    • Metzgeroth G, Erben P, Martin H, et al. Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation. Leukemia. 2012;26(1): 162-164.
    • (2012) Leukemia. , vol.26 , Issue.1 , pp. 162-164
    • Metzgeroth, G.1    Erben, P.2    Martin, H.3
  • 48
    • 0028224348 scopus 로고
    • Fusion of pdgf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
    • Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell. 1994;77(2): 307-316.
    • (1994) Cell. , vol.77 , Issue.2 , pp. 307-316
    • Golub, T.R.1    Barker, G.F.2    Lovett, M.3    Gilliland, D.G.4
  • 49
    • 0036202529 scopus 로고    scopus 로고
    • Myeloproliferative disorders with translocations of chromosome 5q31-35: Role of the platelet-derived growth factor receptor beta
    • Steer EJ, Cross NC. Myeloproliferative disorders with translocations of chromosome 5q31-35: role of the platelet-derived growth factor receptor Beta. Acta Haematol. 2002;107(2): 113-122.
    • (2002) Acta Haematol. , vol.107 , Issue.2 , pp. 113-122
    • Steer, E.J.1    Cross, N.C.2
  • 50
    • 0033529599 scopus 로고    scopus 로고
    • Transforming properties of the huntingtin interacting protein 1/plateletderived growth factor beta receptor fusion protein
    • Ross TS, Gilliland DG. Transforming properties of the Huntingtin interacting protein 1/plateletderived growth factor beta receptor fusion protein. J Biol Chem. 1999;274(32): 22328-22336.
    • (1999) J Biol Chem. , vol.274 , Issue.32 , pp. 22328-22336
    • Ross, T.S.1    Gilliland, D.G.2
  • 51
    • 0037103624 scopus 로고    scopus 로고
    • Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta
    • Apperley JF, Gardembas M, Melo JV, et al. Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta. N Engl J Med. 2002;347(7): 481-487.
    • (2002) N Engl J Med. , vol.347 , Issue.7 , pp. 481-487
    • Apperley, J.F.1    Gardembas, M.2    Melo, J.V.3
  • 52
    • 84902168976 scopus 로고    scopus 로고
    • Patients with myeloid malignancies bearing pdgfrb fusion genes achieve durable longterm remissions with imatinib
    • Cheah CY, Burbury K, Apperley JF, et al. Patients with myeloid malignancies bearing PDGFRB fusion genes achieve durable longterm remissions with imatinib. Blood. 2014; 123(23): 3574-3577.
    • (2014) Blood. , vol.123 , Issue.23 , pp. 3574-3577
    • Cheah, C.Y.1    Burbury, K.2    Apperley, J.F.3
  • 53
    • 84884979496 scopus 로고    scopus 로고
    • Myeloid neoplasms associated with eosinophilia and rearrangement of pdgfra, pdgfrb, and fgfr1: A review
    • Savage N, George TI, Gotlib J. Myeloid neoplasms associated with eosinophilia and rearrangement of PDGFRA, PDGFRB, and FGFR1: a review. Int J Lab Hematol. 2013;35(5): 491-500.
    • (2013) Int J Lab Hematol. , vol.35 , Issue.5 , pp. 491-500
    • Savage, N.1    George, T.I.2    Gotlib, J.3
  • 54
    • 17344373285 scopus 로고    scopus 로고
    • Fgfr1 is fused with a novel zinc-finger gene, znf198, in the t(8;13) leukaemia/lymphoma syndrome
    • Xiao S, Nalabolu SR, Aster JC, et al. FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome. Nat Genet. 1998;18(1): 84-87.
    • (1998) Nat Genet. , vol.18 , Issue.1 , pp. 84-87
    • Xiao, S.1    Nalabolu, S.R.2    Aster, J.C.3
  • 55
    • 0034161335 scopus 로고    scopus 로고
    • Fgfr1 is fused to the centrosome-Associated protein cep110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)
    • Guasch G, Mack GJ, Popovici C, et al. FGFR1 is fused to the centrosome-Associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33). Blood. 2000;95(5): 1788-1796.
    • (2000) Blood. , vol.95 , Issue.5 , pp. 1788-1796
    • Guasch, G.1    Mack, G.J.2    Popovici, C.3
  • 56
    • 0033558253 scopus 로고    scopus 로고
    • The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, fop, to fibroblast growth factor receptor 1
    • Popovici C, Zhang B, Gregoire M-J, et al. The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1. Blood. 1999;93(4): 1381-1389.
    • (1999) Blood. , vol.93 , Issue.4 , pp. 1381-1389
    • Popovici, C.1    Zhang, B.2    Gregoire, M.-J.3
  • 57
    • 0033206227 scopus 로고    scopus 로고
    • Znf198-fgfr1 transforms ba/f3 cells to growth factor independence and results in high level tyrosine phosphorylation of stats 1 and 5
    • Smedley D, Demiroglu A, Abdul-Rauf M, et al. ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5. Neoplasia. 1999;1(4): 349-355.
    • (1999) Neoplasia. , vol.1 , Issue.4 , pp. 349-355
    • Smedley, D.1    Demiroglu, A.2    Abdul-Rauf, M.3
  • 58
    • 0035895067 scopus 로고    scopus 로고
    • The t(8;22) in chronic myeloid leukemia fuses bcr to fgfr1: Transforming activity and specific inhibition of fgfr1 fusion proteins
    • Demiroglu A, Steer EJ, Heath C, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood. 2001; 98(13): 3778-3783.
    • (2001) Blood. , vol.98 , Issue.13 , pp. 3778-3783
    • Demiroglu, A.1    Steer, E.J.2    Heath, C.3
  • 59
    • 1642421743 scopus 로고    scopus 로고
    • Distinct stem cell myeloproliferative/t lymphoma syndromes induced by znf198-fgfr1 and bcr-fgfr1 fusion genes from 8p11 translocations
    • Roumiantsev S, Krause DS, Neumann CA, et al. Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations. Cancer Cell. 2004;5(3): 287-298.
    • (2004) Cancer Cell. , vol.5 , Issue.3 , pp. 287-298
    • Roumiantsev, S.1    Krause, D.S.2    Neumann, C.A.3
  • 60
    • 0036972521 scopus 로고    scopus 로고
    • A fourth case of bcr-fgfr1 positive CML-like disease with t(8;22) translocation showing an extensive deletion on the derivative chromosome 8p
    • Pini M, Gottardi E, Scaravaglio P, et al. A fourth case of BCR-FGFR1 positive CML-like disease with t(8;22) translocation showing an extensive deletion on the derivative chromosome 8p. Hematol J. 2002;3(6): 315-316.
    • (2002) Hematol J. , vol.3 , Issue.6 , pp. 315-316
    • Pini, M.1    Gottardi, E.2    Scaravaglio, P.3
  • 61
    • 42749083134 scopus 로고    scopus 로고
    • Common features of myeloproliferative disorders with t(8;9)(p12;q33) and cep110-fgfr1 fusion: Report of a new case and review of the literature
    • Mozziconacci MJ, Carbuccia N, Prebet T, et al. Common features of myeloproliferative disorders with t(8;9)(p12;q33) and CEP110-FGFR1 fusion: report of a new case and review of the literature. Leuk Res. 2008;32(8): 1304-1308.
    • (2008) Leuk Res. , vol.32 , Issue.8 , pp. 1304-1308
    • Mozziconacci, M.J.1    Carbuccia, N.2    Prebet, T.3
  • 62
    • 11044238012 scopus 로고    scopus 로고
    • Clinical variability of patients with the t(6;8)(q27; p12) and fgfr1op-fgfr1 fusion: Two further cases
    • Vizmanos JL, Hernández R, Vidal MJ, et al. Clinical variability of patients with the t(6;8)(q27; p12) and FGFR1OP-FGFR1 fusion: two further cases. Hematol J. 2004;5(6): 534-537.
    • (2004) Hematol J. , vol.5 , Issue.6 , pp. 534-537
    • Vizmanos, J.L.1    Hernández, R.2    Vidal, M.J.3
  • 63
    • 5144234541 scopus 로고    scopus 로고
    • Pkc412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder
    • Chen J, Deangelo DJ, Kutok JL, et al. PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder. Proc Natl Acad Sci USA. 2004;101(40): 14479-14484.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , Issue.40 , pp. 14479-14484
    • Chen, J.1    Deangelo, D.J.2    Kutok, J.L.3
  • 64
    • 84872087188 scopus 로고    scopus 로고
    • Ponatinib as targeted therapy for fgfr1 fusions associated with the 8p11 myeloproliferative syndrome
    • Chase A, Bryant C, Score J, Cross NC. Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome. Haematologica. 2013;98(1): 103-106.
    • (2013) Haematologica. , vol.98 , Issue.1 , pp. 103-106
    • Chase, A.1    Bryant, C.2    Score, J.3    Cross, N.C.4
  • 65
    • 84933575176 scopus 로고    scopus 로고
    • Clinical activity of ponatinib in a patient with fgfr1-rearranged mixed-phenotype acute leukemia
    • Khodadoust MS, Luo B, Medeiros BC, et al. Clinical activity of ponatinib in a patient with FGFR1-rearranged mixed-phenotype acute leukemia. Leukemia. 2016;30(4): 947-950.
    • (2016) Leukemia. , vol.30 , Issue.4 , pp. 947-950
    • Khodadoust, M.S.1    Luo, B.2    Medeiros, B.C.3
  • 66
    • 85019634417 scopus 로고    scopus 로고
    • Limited efficacy of ponatinib in myeloproliferative neoplasms associated with fgfr1 fusion genes [abstract]
    • Abstract 2812
    • Kreil S, Ades L, Bommer M, et al. Limited efficacy of ponatinib in myeloproliferative neoplasms associated with FGFR1 fusion genes [abstract]. Blood. 2015;126(23). Abstract 2812.
    • (2015) Blood. , vol.126 , Issue.23
    • Kreil, S.1    Ades, L.2    Bommer, M.3
  • 67
    • 20144389913 scopus 로고    scopus 로고
    • The t(8;9) (p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses pcm1 to jak2
    • Reiter A, Walz C, Watmore A, et al. The t(8;9) (p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2. Cancer Res. 2005;65(7): 2662-2667.
    • (2005) Cancer Res. , vol.65 , Issue.7 , pp. 2662-2667
    • Reiter, A.1    Walz, C.2    Watmore, A.3
  • 68
    • 26944481210 scopus 로고    scopus 로고
    • Pcm1-jak2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation
    • Murati A, Gelsi-Boyer V, Adélaïde J, et al. PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation. Leukemia. 2005;19(9): 1692-1696.
    • (2005) Leukemia. , vol.19 , Issue.9 , pp. 1692-1696
    • Murati, A.1    Gelsi-Boyer, V.2    Adélaïde, J.3
  • 69
    • 27944481825 scopus 로고    scopus 로고
    • The t(8;9) (p22;p24) translocation in atypical chronic myeloid leukaemia yields a new pcm1-jak2 fusion gene
    • Bousquet M, Quelen C, De Mas V, et al. The t(8;9) (p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene. Oncogene. 2005;24(48): 7248-7252.
    • (2005) Oncogene. , vol.24 , Issue.48 , pp. 7248-7252
    • Bousquet, M.1    Quelen, C.2    De Mas, V.3
  • 70
    • 0030852328 scopus 로고    scopus 로고
    • Fusion of tel, the ets-variant gene 6 (etv6), to the receptor-Associated kinase jak2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia
    • Peeters P, Raynaud SD, Cools J, et al. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-Associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood. 1997;90(7): 2535-2540.
    • (1997) Blood. , vol.90 , Issue.7 , pp. 2535-2540
    • Peeters, P.1    Raynaud, S.D.2    Cools, J.3
  • 71
    • 84907598217 scopus 로고    scopus 로고
    • Should myeloid and lymphoid neoplasms with pcm1-jak2 and other rearrangements of jak2 be recognized as specific entities
    • Bain BJ, Ahmad S. Should myeloid and lymphoid neoplasms with PCM1-JAK2 and other rearrangements of JAK2 be recognized as specific entities Br J Haematol. 2014;166(6): 809-817.
    • (2014) Br J Haematol. , vol.166 , Issue.6 , pp. 809-817
    • Bain, B.J.1    Ahmad, S.2
  • 72
    • 25844469587 scopus 로고    scopus 로고
    • A bcrjak2 fusion gene as the result of a t(9;22)(p24; q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia
    • Griesinger F, Hennig H, Hillmer F, et al. A BCRJAK2 fusion gene as the result of a t(9;22)(p24; q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia. Genes Chromosomes Cancer. 2005;44(3): 329-333.
    • (2005) Genes Chromosomes Cancer. , vol.44 , Issue.3 , pp. 329-333
    • Griesinger, F.1    Hennig, H.2    Hillmer, F.3
  • 73
    • 43949133894 scopus 로고    scopus 로고
    • A bcrjak2 fusion gene as the result of a t(9;22)(p24; q11) in a patient with acute myeloid leukemia
    • Cirmena G, Aliano S, Fugazza G, et al. A BCRJAK2 fusion gene as the result of a t(9;22)(p24; q11) in a patient with acute myeloid leukemia. Cancer Genet Cytogenet. 2008;183(2): 105-108.
    • (2008) Cancer Genet Cytogenet. , vol.183 , Issue.2 , pp. 105-108
    • Cirmena, G.1    Aliano, S.2    Fugazza, G.3
  • 74
    • 84964587156 scopus 로고    scopus 로고
    • Bcr-jak2 fusion in a myeloproliferative neoplasm with associated eosinophilia
    • He R, Greipp PT, Rangan A, et al. BCR-JAK2 fusion in a myeloproliferative neoplasm with associated eosinophilia. Cancer Genet. 2016; 209(5): 223-228.
    • (2016) Cancer Genet. , vol.209 , Issue.5 , pp. 223-228
    • He, R.1    Greipp, P.T.2    Rangan, A.3
  • 75
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo-And lymphoproliferative disease in mice by retrovirally transduced tel/jak2 fusion genes
    • Schwaller J, Frantsve J, Aster J, et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo-And lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 1998;17(18): 5321-5333.
    • (1998) EMBO J. , vol.17 , Issue.18 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3
  • 76
    • 0034660270 scopus 로고    scopus 로고
    • Tel-jak2 transgenic mice develop t-cell leukemia
    • Carron C, Cormier F, Janin A, et al. TEL-JAK2 transgenic mice develop T-cell leukemia. Blood. 2000;95(12): 3891-3899.
    • (2000) Blood. , vol.95 , Issue.12 , pp. 3891-3899
    • Carron, C.1    Cormier, F.2    Janin, A.3
  • 77
    • 84986593894 scopus 로고    scopus 로고
    • Acquisition of genomic events leading to lymphoblastic transformation in a rare case of myeloproliferative neoplasm with bcr-jak2 fusion transcript
    • Duployez N, Nibourel O, Ducourneau B, et al. Acquisition of genomic events leading to lymphoblastic transformation in a rare case of myeloproliferative neoplasm with BCR-JAK2 fusion transcript. Eur J Haematol. 2016;97(4): 399-402.
    • (2016) Eur J Haematol. , vol.97 , Issue.4 , pp. 399-402
    • Duployez, N.1    Nibourel, O.2    Ducourneau, B.3
  • 78
    • 84865188297 scopus 로고    scopus 로고
    • Ruxolitinib inhibits transforming jak2 fusion proteins in vitro and induces complete cytogenetic remission in t(8;9)(p22;p24)/pcm1-jak2-positive chronic eosinophilic leukemia
    • Lierman E, Selleslag D, Smits S, Billiet J, Vandenberghe P. Ruxolitinib inhibits transforming JAK2 fusion proteins in vitro and induces complete cytogenetic remission in t(8;9)(p22;p24)/PCM1-JAK2-positive chronic eosinophilic leukemia. Blood. 2012;120(7): 1529-1531.
    • (2012) Blood. , vol.120 , Issue.7 , pp. 1529-1531
    • Lierman, E.1    Selleslag, D.2    Smits, S.3    Billiet, J.4    Vandenberghe, P.5
  • 79
    • 84890463961 scopus 로고    scopus 로고
    • Efficacy of ruxolitinib in chronic eosinophilic leukemia associated with a pcm1-jak2 fusion gene
    • Rumi E, Milosevic JD, Casetti I, et al. Efficacy of ruxolitinib in chronic eosinophilic leukemia associated with a PCM1-JAK2 fusion gene. J Clin Oncol. 2013;31(17): e269-e271.
    • (2013) J Clin Oncol. , vol.31 , Issue.17 , pp. e269-e271
    • Rumi, E.1    Milosevic, J.D.2    Casetti, I.3
  • 80
    • 84941994977 scopus 로고    scopus 로고
    • Efficacy of ruxolitinib in myeloid neoplasms with pcm1-jak2 fusion gene
    • Rumi E, Milosevic JD, Selleslag D, et al. Efficacy of ruxolitinib in myeloid neoplasms with PCM1-JAK2 fusion gene. Ann Hematol. 2015;94(11): 1927-1928.
    • (2015) Ann Hematol. , vol.94 , Issue.11 , pp. 1927-1928
    • Rumi, E.1    Milosevic, J.D.2    Selleslag, D.3
  • 81
    • 84926627909 scopus 로고    scopus 로고
    • Limited duration of complete remission on ruxolitinib in myeloid neoplasms with pcm1-jak2 and bcrjak2 fusion genes
    • Schwaab J, Knut M, Haferlach C, et al. Limited duration of complete remission on ruxolitinib in myeloid neoplasms with PCM1-JAK2 and BCRJAK2 fusion genes. Ann Hematol. 2015;94(2): 233-238.
    • (2015) Ann Hematol. , vol.94 , Issue.2 , pp. 233-238
    • Schwaab, J.1    Knut, M.2    Haferlach, C.3
  • 82
    • 67650351086 scopus 로고    scopus 로고
    • Structural and functional alterations of flt3 in acute myeloid leukemia
    • Meshinchi S, Appelbaum FR. Structural and functional alterations of FLT3 in acute myeloid leukemia. Clin Cancer Res. 2009;15(13): 4263-4269.
    • (2009) Clin Cancer Res. , vol.15 , Issue.13 , pp. 4263-4269
    • Meshinchi, S.1    Appelbaum, F.R.2
  • 83
    • 33746169020 scopus 로고    scopus 로고
    • Flt3 is fused to etv6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation
    • Vu HA, Xinh PT, Masuda M, et al. FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation. Leukemia. 2006;20(8): 1414-1421.
    • (2006) Leukemia. , vol.20 , Issue.8 , pp. 1414-1421
    • Vu, H.A.1    Xinh, P.T.2    Masuda, M.3
  • 84
    • 84921812914 scopus 로고    scopus 로고
    • Etv6-flt3 fusion gene-positive, eosinophiliaassociated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplant
    • Falchi L, Mehrotra M, Newberry KJ, et al. ETV6-FLT3 fusion gene-positive, eosinophiliaassociated myeloproliferative neoplasm successfully treated with sorafenib and allogeneic stem cell transplant. Leukemia. 2014; 28(10): 2090-2092.
    • (2014) Leukemia. , vol.28 , Issue.10 , pp. 2090-2092
    • Falchi, L.1    Mehrotra, M.2    Newberry, K.J.3
  • 85
    • 80052162708 scopus 로고    scopus 로고
    • Response of etv6-flt3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of fms-like tyrosine kinase 3
    • Walz C, Erben P, Ritter M, et al. Response of ETV6-FLT3-positive myeloid/lymphoid neoplasm with eosinophilia to inhibitors of FMS-like tyrosine kinase 3. Blood. 2011;118(8): 2239-2242.
    • (2011) Blood. , vol.118 , Issue.8 , pp. 2239-2242
    • Walz, C.1    Erben, P.2    Ritter, M.3
  • 86
    • 84894306352 scopus 로고    scopus 로고
    • Successful allogeneic stem cell transplantation with long-Term remission of etv6/flt3-positive myeloid/lymphoid neoplasm with eosinophilia
    • Chonabayashi K, Hishizawa M, Matsui M, et al. Successful allogeneic stem cell transplantation with long-Term remission of ETV6/FLT3-positive myeloid/lymphoid neoplasm with eosinophilia. Ann Hematol. 2014;93(3): 535-537.
    • (2014) Ann Hematol. , vol.93 , Issue.3 , pp. 535-537
    • Chonabayashi, K.1    Hishizawa, M.2    Matsui, M.3
  • 87
    • 84903904790 scopus 로고    scopus 로고
    • Etv6/flt3 fusion in a mixed-phenotype acute leukemia arising in lymph nodes in a patient with myeloproliferative neoplasm with eosinophilia
    • Hosseini N, Craddock KJ, Salehirad S, et al. ETV6/FLT3 fusion in a mixed-phenotype acute leukemia arising in lymph nodes in a patient with myeloproliferative neoplasm with eosinophilia. J Hematop. 2014;7(2): 71-77.
    • (2014) J Hematop. , vol.7 , Issue.2 , pp. 71-77
    • Hosseini, N.1    Craddock, K.J.2    Salehirad, S.3
  • 88
    • 35448974831 scopus 로고    scopus 로고
    • A constitutively active sptbn1-flt3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy
    • Grand FH, Iqbal S, Zhang L, Russell NH, Chase A, Cross NC. A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy. Exp Hematol. 2007;35(11): 1723-1727.
    • (2007) Exp Hematol. , vol.35 , Issue.11 , pp. 1723-1727
    • Grand, F.H.1    Iqbal, S.2    Zhang, L.3    Russell, N.H.4    Chase, A.5    Cross, N.C.6
  • 89
    • 85000925807 scopus 로고    scopus 로고
    • A novel t(3;13)(q13;q12) translocation fusing flt3 with golgb1: Toward myeloid/lymphoid neoplasms with eosinophilia and rearrangement of flt3 [published online ahead of print 2 December 2016]
    • doi: 10.1038/leu.2016.304
    • Troadec E, Dobbelstein S, Bertrand P, et al. A novel t(3;13)(q13;q12) translocation fusing FLT3 with GOLGB1: toward myeloid/lymphoid neoplasms with eosinophilia and rearrangement of FLT3 [published online ahead of print 2 December 2016] Leukemia. doi: 10.1038/leu.2016.304.
    • Leukemia
    • Troadec, E.1    Dobbelstein, S.2    Bertrand, P.3
  • 90
    • 0035150370 scopus 로고    scopus 로고
    • Molecular cytogenetic and clinical findings in etv6/abl1-positive leukemia
    • Van Limbergen H, Beverloo HB, van Drunen E, et al. Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia. Genes Chromosomes Cancer. 2001;30(3): 274-282.
    • (2001) Genes Chromosomes Cancer. , vol.30 , Issue.3 , pp. 274-282
    • Van Limbergen, H.1    Beverloo, H.B.2    Van Drunen, E.3
  • 91
    • 65749108683 scopus 로고    scopus 로고
    • Insertion (12;9)(p13;q34q34): A cryptic rearrangement involving abl1/etv6 fusion in a patient with philadelphia-negative chronic myeloid leukemia
    • Kelly JC, Shahbazi N, Scheerle J, et al. Insertion (12;9)(p13;q34q34): a cryptic rearrangement involving ABL1/ETV6 fusion in a patient with Philadelphia-negative chronic myeloid leukemia. Cancer Genet Cytogenet. 2009;192(1): 36-39.
    • (2009) Cancer Genet Cytogenet. , vol.192 , Issue.1 , pp. 36-39
    • Kelly, J.C.1    Shahbazi, N.2    Scheerle, J.3
  • 92
    • 84884336369 scopus 로고    scopus 로고
    • Myeloproliferative neoplasm with etv6-Abl1 fusion: A case report and literature review
    • Gancheva K, Virchis A, Howard-Reeves J, et al. Myeloproliferative neoplasm with ETV6-ABL1 fusion: a case report and literature review. Mol Cytogenet. 2013;6(1): 39.
    • (2013) Mol Cytogenet. , vol.6 , Issue.1 , pp. 39
    • Gancheva, K.1    Virchis, A.2    Howard-Reeves, J.3
  • 93
    • 85015336851 scopus 로고    scopus 로고
    • A novel three-way rearrangement involving etv6 (12p13) and abl1 (9q34) with an unknown partner on 3p25 resulting in a possible etv6-Abl1 fusion in a patient with acute myeloid leukemia: A case report and a review of the literature
    • Tirado CA, Siangchin K, Shabsovich DS, Sharifian M, Schiller G. A novel three-way rearrangement involving ETV6 (12p13) and ABL1 (9q34) with an unknown partner on 3p25 resulting in a possible ETV6-ABL1 fusion in a patient with acute myeloid leukemia: a case report and a review of the literature. Biomark Res. 2016;4(1): 16.
    • (2016) Biomark Res. , vol.4 , Issue.1 , pp. 16
    • Tirado, C.A.1    Siangchin, K.2    Shabsovich, D.S.3    Sharifian, M.4    Schiller, G.5
  • 94
    • 84986237322 scopus 로고    scopus 로고
    • Characterization of leukemias with etv6-Abl1 fusion
    • Zaliova M, Moorman AV, Cazzaniga G, et al. Characterization of leukemias with ETV6-ABL1 fusion. Haematologica. 2016;101(9): 1082-1093.
    • (2016) Haematologica. , vol.101 , Issue.9 , pp. 1082-1093
    • Zaliova, M.1    Moorman, A.V.2    Cazzaniga, G.3
  • 95
    • 0036202064 scopus 로고    scopus 로고
    • The 8p11 myeloproliferative syndrome: A distinct clinical entity caused by constitutive activation of fgfr1
    • Macdonald D, Reiter A, Cross NC. The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematol. 2002;107(2): 101-107.
    • (2002) Acta Haematol. , vol.107 , Issue.2 , pp. 101-107
    • Macdonald, D.1    Reiter, A.2    Cross, N.C.3
  • 96
    • 47949114797 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders
    • Cross NC, Reiter A. Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders. Acta Haematol. 2008;119(4): 199-206.
    • (2008) Acta Haematol. , vol.119 , Issue.4 , pp. 199-206
    • Cross, N.C.1    Reiter, A.2
  • 97
    • 84887318253 scopus 로고    scopus 로고
    • Long-Term follow-up of treatment with imatinib in eosinophilia-Associated myeloid/lymphoid neoplasms with pdgfr rearrangements in blast phase
    • Metzgeroth G, Schwaab J, Gosenca D, et al. Long-Term follow-up of treatment with imatinib in eosinophilia-Associated myeloid/lymphoid neoplasms with PDGFR rearrangements in blast phase. Leukemia. 2013;27(11): 2254-2256.
    • (2013) Leukemia. , vol.27 , Issue.11 , pp. 2254-2256
    • Metzgeroth, G.1    Schwaab, J.2    Gosenca, D.3
  • 98
    • 0028932040 scopus 로고
    • Alpha-interferon and hypereosinophilic syndrome with trisomy 8: Karyotypic remission
    • Quiquandon I, Claisse JF, Capiod JC, Delobel J, Prin L. alpha-Interferon and hypereosinophilic syndrome with trisomy 8: karyotypic remission. Blood. 1995;85(8): 2284-2285.
    • (1995) Blood. , vol.85 , Issue.8 , pp. 2284-2285
    • Quiquandon, I.1    Claisse, J.F.2    Capiod, J.C.3    Delobel, J.4    Prin, L.5
  • 99
    • 0031806213 scopus 로고    scopus 로고
    • Clinical and cytogenetic remission induced by interferon-A in a patient with chronic eosinophilic leukemia associated with a unique t(3;9;5) translocation
    • Yamada O, Kitahara K, Imamura K, Ozasa H, Okada M, Mizoguchi H. Clinical and cytogenetic remission induced by interferon-A in a patient with chronic eosinophilic leukemia associated with a unique t(3;9;5) translocation. Am J Hematol. 1998;58(2): 137-141.
    • (1998) Am J Hematol. , vol.58 , Issue.2 , pp. 137-141
    • Yamada, O.1    Kitahara, K.2    Imamura, K.3    Ozasa, H.4    Okada, M.5    Mizoguchi, H.6
  • 100
    • 47649099919 scopus 로고    scopus 로고
    • Interferon alpha induces a good molecular response in a patient with chronic eosinophilic leukemia (cel) carrying the jak2v617f point mutation
    • Helbig G, Stella-Holowiecka B, Majewski M, Lewandowska M, Holowiecki J. Interferon alpha induces a good molecular response in a patient with chronic eosinophilic leukemia (CEL) carrying the JAK2V617F point mutation. Haematologica. 2007;92(11): e118-e119.
    • (2007) Haematologica. , vol.92 , Issue.11 , pp. e118-e119
    • Helbig, G.1    Stella-Holowiecka, B.2    Majewski, M.3    Lewandowska, M.4    Holowiecki, J.5
  • 101
    • 84861346705 scopus 로고    scopus 로고
    • Chronic eosinophilic leukemia-not otherwise specified has a poor prognosis with unresponsiveness to conventional treatment and high risk of acute transformation
    • Helbig G, Soja A, Bartkowska-Chrobok A, Kyrcz-Krzemién S. Chronic eosinophilic leukemia-not otherwise specified has a poor prognosis with unresponsiveness to conventional treatment and high risk of acute transformation. Am J Hematol. 2012;87(6): 643-645.
    • (2012) Am J Hematol. , vol.87 , Issue.6 , pp. 643-645
    • Helbig, G.1    Soja, A.2    Bartkowska-Chrobok, A.3    Kyrcz-Krzemién, S.4
  • 102
    • 84966667293 scopus 로고    scopus 로고
    • Predictors of survival in who-defined hypereosinophilic syndrome and idiopathic hypereosinophilia and the role of next-generation sequencing
    • Pardanani A, Lasho T, Wassie E, et al. Predictors of survival in WHO-defined hypereosinophilic syndrome and idiopathic hypereosinophilia and the role of next-generation sequencing. Leukemia. 2016;30(9): 1924-1926.
    • (2016) Leukemia. , vol.30 , Issue.9 , pp. 1924-1926
    • Pardanani, A.1    Lasho, T.2    Wassie, E.3
  • 103
    • 84968615956 scopus 로고    scopus 로고
    • Targeted nextgeneration sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified
    • Wang SA, Tam W, Tsai AG, et al. Targeted nextgeneration sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified. Mod Pathol. 2016;29(8): 854-864.
    • (2016) Mod Pathol. , vol.29 , Issue.8 , pp. 854-864
    • Wang, S.A.1    Tam, W.2    Tsai, A.G.3


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