Molecular cytogenetic and clinical findings in ETV6/ABLI-positive leukemia

Genes Chromosomes and Cancer

Volumn 30, Issue 3, 2001, Pages 274-282

  Van Limbergen, Heidi ^a   Berna Beverloo, H ^b   Van Drunen, Ellen ^c   Janssens, Ann ^a   Hhlen, Karel ^d   Poppe, Bruce ^c   Van Roy, Nadine ^c   Marynen, Peter ^e   De Paepe, Anne ^b,e   Slater, Rosalyn ^a,b,d   Speleman, Frank ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN ABL1; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG;

ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CHROMOSOME 12P; CHROMOSOME BREAKAGE; CHROMOSOME REARRANGEMENT; CHRONIC MYELOID LEUKEMIA; CYTOGENETICS; ENZYME ACTIVITY; FUSION GENE; HUMAN; HUMAN CELL; MALE; ONCOGENE; PRESCHOOL CHILD; PRIORITY JOURNAL; T CELL LEUKEMIA;

EID: 0035150370     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2264(2000)9999:9999<1::aid-gcc1089>3.0.co;2-1     Document Type: Article

References (25)

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5. A TEL/ABL fusion gene on chromosome 12p13 in a case of Ph-, BCR- atypical CML
6. Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes
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8. Development of an interphase fluorescence in situ hybridization (FISH) test to detect t(8;21) in AML patients
9. A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation
10. The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event
11. A novel ETV6-NTKR3 gene fusion in congenital fibrosarcoma
12. Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases
13. cDNA cloning, tissue distribution, and chromosomal localization of myelodysplasia/myeloid leukemia factor 2 (MLF2)
14. The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11 and 19p13.2-p13.1 in regions of neoplasia-associated translocation
15. Detection of residual BCR/ABL transcripts in chronic myeloid leukaemia patients in complete remission using the polymerase chain reaction and nested primers
16. A complete set of human telomeric probes and their clinical application
17. ETV6/ABL fusion is rare in Ph-negative chronic myeloid disorders
18. p210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines
19. The novel activation of ABL by fusion to an ets-related gene, TEL
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21. The role of chromosome translocations in leukemogenesis
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23. 1;17 Translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines
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