-
1
-
-
84902081189
-
JAK inhibition in the myeloproliferative neoplasms: lessons learned from the bench and bedside
-
Gotlib J. JAK inhibition in the myeloproliferative neoplasms: lessons learned from the bench and bedside. Hematology Am Soc Hematol Educ Program 2013, 2013:529-537.
-
(2013)
Hematology Am Soc Hematol Educ Program
, vol.2013
, pp. 529-537
-
-
Gotlib, J.1
-
2
-
-
79951510594
-
JAK2 inhibitors: what's the true therapeutic potential?
-
Santos F.P., Verstovsek S. JAK2 inhibitors: what's the true therapeutic potential?. Blood Rev 2011, 25:53-63.
-
(2011)
Blood Rev
, vol.25
, pp. 53-63
-
-
Santos, F.P.1
Verstovsek, S.2
-
3
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine R.L., Wadleigh M., Cools J., et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005, 7:387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
4
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C., Ugo V., Le Couedic J.P., et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005, 434:1144-1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
5
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R., Passamonti F., Buser A.S., et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005, 352:1779-1790.
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
-
6
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter E.J., Scott L.M., Campbell P.J., et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005, 365:1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
-
7
-
-
78049370405
-
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma
-
Green M.R., Monti S., Rodig S.J., et al. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood 2010, 116:3268-3277.
-
(2010)
Blood
, vol.116
, pp. 3268-3277
-
-
Green, M.R.1
Monti, S.2
Rodig, S.J.3
-
8
-
-
84907598217
-
Should myeloid and lymphoid neoplasms with PCM1-JAK2 and other rearrangements of JAK2 be recognized as specific entities?
-
Bain B.J., Ahmad S. Should myeloid and lymphoid neoplasms with PCM1-JAK2 and other rearrangements of JAK2 be recognized as specific entities?. Br J Haematol 2014, 166:809-817.
-
(2014)
Br J Haematol
, vol.166
, pp. 809-817
-
-
Bain, B.J.1
Ahmad, S.2
-
9
-
-
25844469587
-
A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia
-
Griesinger F., Hennig H., Hillmer F., et al. A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia. Genes Chromosomes Cancer 2005, 44:329-333.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 329-333
-
-
Griesinger, F.1
Hennig, H.2
Hillmer, F.3
-
10
-
-
43949133894
-
A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia
-
Cirmena G., Aliano S., Fugazza G., et al. A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia. Cancer Genet Cytogenet 2008, 183:105-108.
-
(2008)
Cancer Genet Cytogenet
, vol.183
, pp. 105-108
-
-
Cirmena, G.1
Aliano, S.2
Fugazza, G.3
-
11
-
-
47649133542
-
Leukaemia cutis in atypical chronic myeloid leukaemia with a t(9;22) (p24;q11.2) leading to BCR-JAK2 fusion
-
Lane S.W., Fairbairn D.J., McCarthy C., et al. Leukaemia cutis in atypical chronic myeloid leukaemia with a t(9;22) (p24;q11.2) leading to BCR-JAK2 fusion. Br J Haematol 2008, 142:503.
-
(2008)
Br J Haematol
, vol.142
, pp. 503
-
-
Lane, S.W.1
Fairbairn, D.J.2
McCarthy, C.3
-
12
-
-
80052062420
-
Chromosomal translocation t(9;22)(p24;q11) appears to be recurrently associated with myeloid malignancy with aggressive course
-
Angelova S., Spassova S., Toshkov S., et al. Chromosomal translocation t(9;22)(p24;q11) appears to be recurrently associated with myeloid malignancy with aggressive course. Leuk Lymphoma 2011, 52:1809-1810.
-
(2011)
Leuk Lymphoma
, vol.52
, pp. 1809-1810
-
-
Angelova, S.1
Spassova, S.2
Toshkov, S.3
-
13
-
-
84856007547
-
Two alternatively spliced 5'BCR/3'JAK2 fusion transcripts in a myeloproliferative neoplasm with a three-way t(9;18;22)(p23;p11.3;q11.2) translocation
-
Impera L., Lonoce A., Fanfulla D.A., et al. Two alternatively spliced 5'BCR/3'JAK2 fusion transcripts in a myeloproliferative neoplasm with a three-way t(9;18;22)(p23;p11.3;q11.2) translocation. Cancer Genet 2011, 204:512-515.
-
(2011)
Cancer Genet
, vol.204
, pp. 512-515
-
-
Impera, L.1
Lonoce, A.2
Fanfulla, D.A.3
-
14
-
-
84857558600
-
Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase
-
Cuesta-Dominguez A., Ortega M., Ormazabal C., et al. Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase. PLoS ONE 2012, 7:e32451.
-
(2012)
PLoS ONE
, vol.7
, pp. e32451
-
-
Cuesta-Dominguez, A.1
Ortega, M.2
Ormazabal, C.3
-
15
-
-
84862200795
-
BCR-JAK2 fusion as a result of a translocation (9;22)(p24;q11.2) in a patient with CML-like myeloproliferative disease
-
Elnaggar M.M., Agersborg S., Sahoo T., et al. BCR-JAK2 fusion as a result of a translocation (9;22)(p24;q11.2) in a patient with CML-like myeloproliferative disease. Mol Cytogenet 2012, 5:23.
-
(2012)
Mol Cytogenet
, vol.5
, pp. 23
-
-
Elnaggar, M.M.1
Agersborg, S.2
Sahoo, T.3
-
16
-
-
84865118132
-
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
-
Roberts K.G., Morin R.D., Zhang J., et al. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell 2012, 22:153-166.
-
(2012)
Cancer Cell
, vol.22
, pp. 153-166
-
-
Roberts, K.G.1
Morin, R.D.2
Zhang, J.3
-
17
-
-
84881531298
-
Atypical chronic myeloid leukemia with t(9;22)(p24,11.2), a BCR-JAK2 fusion gene
-
Bellesso M., Santucci R., Dias D.F., et al. Atypical chronic myeloid leukemia with t(9;22)(p24,11.2), a BCR-JAK2 fusion gene. Rev Bras Hematol Hemoter 2013, 35:218-219.
-
(2013)
Rev Bras Hematol Hemoter
, vol.35
, pp. 218-219
-
-
Bellesso, M.1
Santucci, R.2
Dias, D.F.3
-
18
-
-
84884483475
-
A BCR-JAK2 fusion gene from ins(22;9)(q11;p13p24) in a patient with atypical chronic myeloid leukemia
-
Xu Y., Yin J., Pan J., et al. A BCR-JAK2 fusion gene from ins(22;9)(q11;p13p24) in a patient with atypical chronic myeloid leukemia. Leuk Lymphoma 2013, 54:2322-2324.
-
(2013)
Leuk Lymphoma
, vol.54
, pp. 2322-2324
-
-
Xu, Y.1
Yin, J.2
Pan, J.3
-
19
-
-
84969727351
-
Transformation of an unclassified myeloproliferative neoplasm with a rare BCR-JAK2 fusion transcript resulting from the translocation (9;22)(p24;q11)
-
252537
-
Chamseddine A.N., Etancelin P., Penther D., et al. Transformation of an unclassified myeloproliferative neoplasm with a rare BCR-JAK2 fusion transcript resulting from the translocation (9;22)(p24;q11). Case Rep Hematol 2015, 2015. 252537.
-
(2015)
Case Rep Hematol
, vol.2015
-
-
Chamseddine, A.N.1
Etancelin, P.2
Penther, D.3
-
20
-
-
84941426666
-
Myelodysplastic syndrome with t(9;22)(p24;q11.2), a BCR-JAK2 fusion: case report and review of the literature
-
Kantarcioglu B., Kaygusuz-Atagunduz I., Uzay A., et al. Myelodysplastic syndrome with t(9;22)(p24;q11.2), a BCR-JAK2 fusion: case report and review of the literature. Int J Hematol 2015, 102:383-387.
-
(2015)
Int J Hematol
, vol.102
, pp. 383-387
-
-
Kantarcioglu, B.1
Kaygusuz-Atagunduz, I.2
Uzay, A.3
-
21
-
-
84926627909
-
Limited duration of complete remission on ruxolitinib in myeloid neoplasms with PCM1-JAK2 and BCR-JAK2 fusion genes
-
Schwaab J., Knut M., Haferlach C., et al. Limited duration of complete remission on ruxolitinib in myeloid neoplasms with PCM1-JAK2 and BCR-JAK2 fusion genes. Ann Hematol 2015, 94:233-238.
-
(2015)
Ann Hematol
, vol.94
, pp. 233-238
-
-
Schwaab, J.1
Knut, M.2
Haferlach, C.3
-
22
-
-
78149358109
-
Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia
-
Tirado C.A., Chen W., Huang L.J., et al. Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia. Leuk Res 2010, 34:1674-1676.
-
(2010)
Leuk Res
, vol.34
, pp. 1674-1676
-
-
Tirado, C.A.1
Chen, W.2
Huang, L.J.3
-
23
-
-
33644969827
-
Validation of two clinically useful assays for evaluation of JAK2 V617F mutation in chronic myeloproliferative disorders
-
McClure R., Mai M., Lasho T. Validation of two clinically useful assays for evaluation of JAK2 V617F mutation in chronic myeloproliferative disorders. Leukemia 2006, 20:168-171.
-
(2006)
Leukemia
, vol.20
, pp. 168-171
-
-
McClure, R.1
Mai, M.2
Lasho, T.3
-
24
-
-
84969655484
-
Sensitive and rapid detection of CALR somatic mutations in myeloproliferative neoplasms using PCR and fragment analysis
-
He R., Mai M., Wood A.J., et al. Sensitive and rapid detection of CALR somatic mutations in myeloproliferative neoplasms using PCR and fragment analysis. J Mol Diagn 2014, 16:1.
-
(2014)
J Mol Diagn
, vol.16
, pp. 1
-
-
He, R.1
Mai, M.2
Wood, A.J.3
-
25
-
-
84877761530
-
Hematologic malignancies with PCM1-JAK2 gene fusion share characteristics with myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1
-
Patterer V., Schnittger S., Kern W., et al. Hematologic malignancies with PCM1-JAK2 gene fusion share characteristics with myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1. Ann Hematol 2013, 92:759-769.
-
(2013)
Ann Hematol
, vol.92
, pp. 759-769
-
-
Patterer, V.1
Schnittger, S.2
Kern, W.3
-
26
-
-
0027422977
-
A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins
-
McWhirter J.R., Galasso D.L., Wang J.Y. A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins. Mol Cell Biol 1993, 13:7587-7595.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7587-7595
-
-
McWhirter, J.R.1
Galasso, D.L.2
Wang, J.Y.3
-
27
-
-
84929296119
-
BCR-JAK2 drives a myeloproliferative neoplasm in transplanted mice
-
Cuesta-Dominguez A., Leon-Rico D., Alvarez L., et al. BCR-JAK2 drives a myeloproliferative neoplasm in transplanted mice. J Pathol 2015, 236:219-228.
-
(2015)
J Pathol
, vol.236
, pp. 219-228
-
-
Cuesta-Dominguez, A.1
Leon-Rico, D.2
Alvarez, L.3
-
28
-
-
84865188297
-
Ruxolitinib inhibits transforming JAK2 fusion proteins in vitro and induces complete cytogenetic remission in t(8;9)(p22;p24)/PCM1-JAK2-positive chronic eosinophilic leukemia
-
Lierman E., Selleslag D., Smits S., et al. Ruxolitinib inhibits transforming JAK2 fusion proteins in vitro and induces complete cytogenetic remission in t(8;9)(p22;p24)/PCM1-JAK2-positive chronic eosinophilic leukemia. Blood 2012, 120:1529-1531.
-
(2012)
Blood
, vol.120
, pp. 1529-1531
-
-
Lierman, E.1
Selleslag, D.2
Smits, S.3
-
29
-
-
84890463961
-
Efficacy of ruxolitinib in chronic eosinophilic leukemia associated with a PCM1-JAK2 fusion gene
-
Rumi E., Milosevic J.D., Casetti I., et al. Efficacy of ruxolitinib in chronic eosinophilic leukemia associated with a PCM1-JAK2 fusion gene. J Clin Oncol 2013, 31:e269-e271.
-
(2013)
J Clin Oncol
, vol.31
, pp. e269-e271
-
-
Rumi, E.1
Milosevic, J.D.2
Casetti, I.3
-
30
-
-
52949089050
-
JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies
-
Vainchenker W., Dusa A., Constantinescu S.N. JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies. Semin Cell Dev Biol 2008, 19:385-393.
-
(2008)
Semin Cell Dev Biol
, vol.19
, pp. 385-393
-
-
Vainchenker, W.1
Dusa, A.2
Constantinescu, S.N.3
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