메뉴 건너뛰기




Volumn 129, Issue 1, 2017, Pages 38-47

Spectrum of somatic mutation dynamics in chronic myeloid leukemia following tyrosine kinase inhibitor therapy

Author keywords

[No Author keywords available]

Indexed keywords

DASATINIB; IMATINIB; NILOTINIB; PROTEIN TYROSINE KINASE INHIBITOR; RADOTINIB; ANTINEOPLASTIC AGENT; PROTEIN KINASE INHIBITOR;

EID: 85014909859     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2016-04-708560     Document Type: Article
Times cited : (98)

References (49)
  • 1
    • 0015694748 scopus 로고
    • Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • Rowley JD. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature. 1973;243(5405):290-293.
    • (1973) Nature , vol.243 , Issue.5405 , pp. 290-293
    • Rowley, J.D.1
  • 2
    • 10744233716 scopus 로고    scopus 로고
    • Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
    • O'Brien SG, Guilhot F, Larson RA, et al; IRIS Investigators. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med. 2003;348(11):994-1004.
    • (2003) N Engl J Med , vol.348 , Issue.11 , pp. 994-1004
    • O'Brien, S.G.1    Guilhot, F.2    Larson, R.A.3
  • 3
    • 19944428353 scopus 로고    scopus 로고
    • Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
    • Lombardo LJ, Lee FY, Chen P, et al. Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem. 2004;47(27):6658-6661.
    • (2004) J Med Chem , vol.47 , Issue.27 , pp. 6658-6661
    • Lombardo, L.J.1    Lee, F.Y.2    Chen, P.3
  • 4
    • 13844251975 scopus 로고    scopus 로고
    • Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
    • published correction appears in Cancer Cell. 2005;7(4):399
    • Weisberg E, Manley PW, Breitenstein W, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl [published correction appears in Cancer Cell. 2005;7(4):399]. Cancer Cell. 2005;7(2):129-141.
    • (2005) Cancer Cell , vol.7 , Issue.2 , pp. 129-141
    • Weisberg, E.1    Manley, P.W.2    Breitenstein, W.3
  • 5
    • 84864446464 scopus 로고    scopus 로고
    • How I treat CML blast crisis
    • Hehlmann R. How I treat CML blast crisis. Blood. 2012;120(4):737-747.
    • (2012) Blood , vol.120 , Issue.4 , pp. 737-747
    • Hehlmann, R.1
  • 6
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med. 2013;368(22):2059-2074.
    • (2013) N Engl J Med , vol.368 , Issue.22 , pp. 2059-2074
  • 7
    • 84888219405 scopus 로고    scopus 로고
    • Clinical and biological implications of driver mutations in myelodysplastic syndromes
    • Papaemmanuil E, Gerstung M, Malcovati L, et al; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood. 2013;122(22):3616-3627.
    • (2013) Blood , vol.122 , Issue.22 , pp. 3616-3627
    • Papaemmanuil, E.1    Gerstung, M.2    Malcovati, L.3
  • 8
    • 84863337617 scopus 로고    scopus 로고
    • Clonal architecture of secondary acute myeloid leukemia
    • Walter MJ, Shen D, Ding L, et al. Clonal architecture of secondary acute myeloid leukemia. N Engl J Med. 2012;366(12):1090-1098.
    • (2012) N Engl J Med , vol.366 , Issue.12 , pp. 1090-1098
    • Walter, M.J.1    Shen, D.2    Ding, L.3
  • 9
    • 84881020319 scopus 로고    scopus 로고
    • Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia
    • Sakaguchi H, Okuno Y, Muramatsu H, et al. Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia. Nat Genet. 2013;45(8):937-941.
    • (2013) Nat Genet , vol.45 , Issue.8 , pp. 937-941
    • Sakaguchi, H.1    Okuno, Y.2    Muramatsu, H.3
  • 10
    • 84961554506 scopus 로고    scopus 로고
    • Acute myeloid leukemia ontogeny is defined by distinct somatic mutations
    • Lindsley RC, Mar BG, Mazzola E, et al. Acute myeloid leukemia ontogeny is defined by distinct somatic mutations. Blood. 2015;125(9):1367-1376.
    • (2015) Blood , vol.125 , Issue.9 , pp. 1367-1376
    • Lindsley, R.C.1    Mar, B.G.2    Mazzola, E.3
  • 11
    • 84871988651 scopus 로고    scopus 로고
    • Recurrent SETBP1 mutations in atypical chronic myeloid leukemia
    • Piazza R, Valletta S, Winkelmann N, et al. Recurrent SETBP1 mutations in atypical chronic myeloid leukemia. Nat Genet. 2013;45(1):18-24.
    • (2013) Nat Genet , vol.45 , Issue.1 , pp. 18-24
    • Piazza, R.1    Valletta, S.2    Winkelmann, N.3
  • 12
    • 80053900941 scopus 로고    scopus 로고
    • Frequent pathway mutations of splicing machinery in myelodysplasia
    • Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature. 2011;478(7367):64-69.
    • (2011) Nature , vol.478 , Issue.7367 , pp. 64-69
    • Yoshida, K.1    Sanada, M.2    Shiraishi, Y.3
  • 13
    • 84877608004 scopus 로고    scopus 로고
    • Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML
    • Maxson JE, Gotlib J, Pollyea DA, et al. Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML. N Engl J Med. 2013;368(19):1781-1790.
    • (2013) N Engl J Med , vol.368 , Issue.19 , pp. 1781-1790
    • Maxson, J.E.1    Gotlib, J.2    Pollyea, D.A.3
  • 14
    • 33750077276 scopus 로고    scopus 로고
    • Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate
    • Jabbour E, Kantarjian H, Jones D, et al. Frequency and clinical significance of BCR-ABL mutations in patients with chronic myeloid leukemia treated with imatinib mesylate. Leukemia. 2006;20(10):1767-1773.
    • (2006) Leukemia , vol.20 , Issue.10 , pp. 1767-1773
    • Jabbour, E.1    Kantarjian, H.2    Jones, D.3
  • 15
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
    • Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001;293(5531):876-880.
    • (2001) Science , vol.293 , Issue.5531 , pp. 876-880
    • Gorre, M.E.1    Mohammed, M.2    Ellwood, K.3
  • 16
    • 0036850514 scopus 로고    scopus 로고
    • Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy
    • Hochhaus A, Kreil S, Corbin AS, et al. Molecular and chromosomal mechanisms of resistance to imatinib (STI571) therapy. Leukemia. 2002;16(11):2190-2196.
    • (2002) Leukemia , vol.16 , Issue.11 , pp. 2190-2196
    • Hochhaus, A.1    Kreil, S.2    Corbin, A.S.3
  • 17
    • 0037045583 scopus 로고    scopus 로고
    • BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: A prospective study
    • von Bubnoff N, Schneller F, Peschel C, Duyster J. BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study. Lancet. 2002;359(9305):487-491.
    • (2002) Lancet , vol.359 , Issue.9305 , pp. 487-491
    • Von Bubnoff, N.1    Schneller, F.2    Peschel, C.3    Duyster, J.4
  • 18
    • 0036566540 scopus 로고    scopus 로고
    • High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance
    • Branford S, Rudzki Z, Walsh S, et al. High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance. Blood. 2002;99(9):3472-3475.
    • (2002) Blood , vol.99 , Issue.9 , pp. 3472-3475
    • Branford, S.1    Rudzki, Z.2    Walsh, S.3
  • 19
    • 0036678472 scopus 로고    scopus 로고
    • Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop
    • Roumiantsev S, Shah NP, Gorre ME, et al. Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop. Proc Natl Acad Sci USA. 2002;99(16):10700-10705.
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.16 , pp. 10700-10705
    • Roumiantsev, S.1    Shah, N.P.2    Gorre, M.E.3
  • 20
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • Shah NP, Nicoll JM, Nagar B, et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2002;2(2):117-125.
    • (2002) Cancer Cell , vol.2 , Issue.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3
  • 21
    • 84940797444 scopus 로고    scopus 로고
    • BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase
    • Hughes TP, Saglio G, Quintás-Cardama A, et al. BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase. Leukemia. 2015;29(9):1832-1838.
    • (2015) Leukemia , vol.29 , Issue.9 , pp. 1832-1838
    • Hughes, T.P.1    Saglio, G.2    Quintás-Cardama, A.3
  • 22
    • 84904887484 scopus 로고    scopus 로고
    • Prognosis for patients with CML and >10% BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline
    • Branford S, Yeung DT, Parker WT, et al. Prognosis for patients with CML and >10% BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline. Blood. 2014;124(4):511-518.
    • (2014) Blood , vol.124 , Issue.4 , pp. 511-518
    • Branford, S.1    Yeung, D.T.2    Parker, W.T.3
  • 23
    • 84908364892 scopus 로고    scopus 로고
    • BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia
    • Zabriskie MS, Eide CA, Tantravahi SK, et al. BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia. Cancer Cell. 2014;26(3):428-442.
    • (2014) Cancer Cell , vol.26 , Issue.3 , pp. 428-442
    • Zabriskie, M.S.1    Eide, C.A.2    Tantravahi, S.K.3
  • 24
    • 84931403778 scopus 로고    scopus 로고
    • Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase
    • Machova Polakova K, Kulvait V, Benesova A, et al. Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase. J Cancer Res Clin Oncol. 2015;141(5):887-899.
    • (2015) J Cancer Res Clin Oncol , vol.141 , Issue.5 , pp. 887-899
    • Machova Polakova, K.1    Kulvait, V.2    Benesova, A.3
  • 25
    • 84860752177 scopus 로고    scopus 로고
    • BCR-ABL1 doubling times more reliably assess the dynamics of CML relapse compared with the BCR-ABL1 fold rise: Implications for monitoring and management
    • Branford S, Yeung DT, Prime JA, et al. BCR-ABL1 doubling times more reliably assess the dynamics of CML relapse compared with the BCR-ABL1 fold rise: implications for monitoring and management. Blood. 2012;119(18):4264-4271.
    • (2012) Blood , vol.119 , Issue.18 , pp. 4264-4271
    • Branford, S.1    Yeung, D.T.2    Prime, J.A.3
  • 26
    • 84872462658 scopus 로고    scopus 로고
    • BCR-ABL1 compound mutations in tyrosine kinase inhibitor-resistant CML: Frequency and clonal relationships
    • Khorashad JS, Kelley TW, Szankasi P, et al. BCR-ABL1 compound mutations in tyrosine kinase inhibitor-resistant CML: frequency and clonal relationships. Blood. 2013;121(3):489-498.
    • (2013) Blood , vol.121 , Issue.3 , pp. 489-498
    • Khorashad, J.S.1    Kelley, T.W.2    Szankasi, P.3
  • 27
    • 79952451556 scopus 로고    scopus 로고
    • A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases
    • Grossmann V, Kohlmann A, Zenger M, et al. A deep-sequencing study of chronic myeloid leukemia patients in blast crisis (BC-CML) detects mutations in 76.9% of cases. Leukemia. 2011;25(3):557-560.
    • (2011) Leukemia , vol.25 , Issue.3 , pp. 557-560
    • Grossmann, V.1    Kohlmann, A.2    Zenger, M.3
  • 28
    • 84888394639 scopus 로고    scopus 로고
    • ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia
    • Menezes J, Salgado RN, Acquadro F, et al. ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia. Blood Cancer J. 2013;3(11):e157.
    • (2013) Blood Cancer J , vol.3 , Issue.11 , pp. e157
    • Menezes, J.1    Salgado, R.N.2    Acquadro, F.3
  • 29
    • 79957593717 scopus 로고    scopus 로고
    • CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
    • Makishima H, Jankowska AM, McDevitt MA, et al. CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia. Blood. 2011;117(21):e198-e206.
    • (2011) Blood , vol.117 , Issue.21 , pp. e198-e206
    • Makishima, H.1    Jankowska, A.M.2    McDevitt, M.A.3
  • 30
    • 79960101630 scopus 로고    scopus 로고
    • Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia
    • Jelinek J, Gharibyan V, Estecio MRH, et al. Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia. PLoS One. 2011;6(7):e22110.
    • (2011) PLoS One , vol.6 , Issue.7
    • Jelinek, J.1    Gharibyan, V.2    Estecio, M.R.H.3
  • 31
    • 84855241107 scopus 로고    scopus 로고
    • Aberrant methylation in promoter-associated CpG islands of multiple genes in chronic myelogenous leukemia blast crisis
    • Uehara E, Takeuchi S, Yang Y, et al. Aberrant methylation in promoter-associated CpG islands of multiple genes in chronic myelogenous leukemia blast crisis. Oncol Lett. 2012;3(1):190-192.
    • (2012) Oncol Lett , vol.3 , Issue.1 , pp. 190-192
    • Uehara, E.1    Takeuchi, S.2    Yang, Y.3
  • 32
    • 84925284228 scopus 로고    scopus 로고
    • Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status
    • Schmidt M, Rinke J, Schäfer V, et al. Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status. Leukemia. 2014;28(12):2292-2299.
    • (2014) Leukemia , vol.28 , Issue.12 , pp. 2292-2299
    • Schmidt, M.1    Rinke, J.2    Schäfer, V.3
  • 33
    • 84923222685 scopus 로고    scopus 로고
    • Preleukemia: The normal side of cancer
    • Shlush LI, Minden MD. Preleukemia: the normal side of cancer. Curr Opin Hematol. 2015;22(2):77-84.
    • (2015) Curr Opin Hematol , vol.22 , Issue.2 , pp. 77-84
    • Shlush, L.I.1    Minden, M.D.2
  • 34
    • 84881298446 scopus 로고    scopus 로고
    • European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013
    • Baccarani M, Deininger MW, Rosti G, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood. 2013;122(6):872-884.
    • (2013) Blood , vol.122 , Issue.6 , pp. 872-884
    • Baccarani, M.1    Deininger, M.W.2    Rosti, G.3
  • 35
    • 84868554484 scopus 로고    scopus 로고
    • Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
    • Dolnik A, Engelmann JC, Scharfenberger-Schmeer M, et al. Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing. Blood. 2012;120(18):e83-e92.
    • (2012) Blood , vol.120 , Issue.18 , pp. e83-e92
    • Dolnik, A.1    Engelmann, J.C.2    Scharfenberger-Schmeer, M.3
  • 36
    • 1542283736 scopus 로고    scopus 로고
    • Acquired somatic ATRX mutations in myelodysplastic syndrome associated with alpha thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations
    • Steensma DP, Higgs DR, Fisher CA, Gibbons RJ. Acquired somatic ATRX mutations in myelodysplastic syndrome associated with alpha thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations. Blood. 2004;103(6):2019-2026.
    • (2004) Blood , vol.103 , Issue.6 , pp. 2019-2026
    • Steensma, D.P.1    Higgs, D.R.2    Fisher, C.A.3    Gibbons, R.J.4
  • 37
    • 84882738740 scopus 로고    scopus 로고
    • The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome
    • Larsson CA, Cote G, Quintás-Cardama A. The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome. Mol Cancer Res. 2013;11(8):815-827.
    • (2013) Mol Cancer Res , vol.11 , Issue.8 , pp. 815-827
    • Larsson, C.A.1    Cote, G.2    Quintás-Cardama, A.3
  • 38
    • 23044458596 scopus 로고    scopus 로고
    • ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: A study by the GIMEMA Working Party on Chronic Myeloid Leukemia
    • Soverini S, Martinelli G, Rosti G, et al. ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party on Chronic Myeloid Leukemia. J Clin Oncol. 2005;23(18):4100-4109.
    • (2005) J Clin Oncol , vol.23 , Issue.18 , pp. 4100-4109
    • Soverini, S.1    Martinelli, G.2    Rosti, G.3
  • 39
    • 80051573352 scopus 로고    scopus 로고
    • BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: Recommendations from an expert panel on behalf of European LeukemiaNet
    • Soverini S, Hochhaus A, Nicolini FE, et al. BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. Blood. 2011;118(5):1208-1215.
    • (2011) Blood , vol.118 , Issue.5 , pp. 1208-1215
    • Soverini, S.1    Hochhaus, A.2    Nicolini, F.E.3
  • 40
    • 84898547095 scopus 로고    scopus 로고
    • Driver mutations of cancer epigenomes
    • Roy DM, Walsh LA, Chan TA. Driver mutations of cancer epigenomes. Protein Cell. 2014;5(4):265-296.
    • (2014) Protein Cell , vol.5 , Issue.4 , pp. 265-296
    • Roy, D.M.1    Walsh, L.A.2    Chan, T.A.3
  • 41
    • 84940545016 scopus 로고    scopus 로고
    • Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia
    • Klco JM, Miller CA, Griffith M, et al. Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia. JAMA. 2015;314(8):811-822.
    • (2015) JAMA , vol.314 , Issue.8 , pp. 811-822
    • Klco, J.M.1    Miller, C.A.2    Griffith, M.3
  • 42
    • 84937904208 scopus 로고    scopus 로고
    • Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
    • Steensma DP, Bejar R, Jaiswal S, et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood. 2015;126(1):9-16.
    • (2015) Blood , vol.126 , Issue.1 , pp. 9-16
    • Steensma, D.P.1    Bejar, R.2    Jaiswal, S.3
  • 43
    • 84920053873 scopus 로고    scopus 로고
    • Age-related clonal hematopoiesis associated with adverse outcomes
    • Jaiswal S, Fontanillas P, Flannick J, et al. Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med. 2014;371(26):2488-2498.
    • (2014) N Engl J Med , vol.371 , Issue.26 , pp. 2488-2498
    • Jaiswal, S.1    Fontanillas, P.2    Flannick, J.3
  • 44
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • published correction appears in Nature. 2014;508(7496):420
    • Shlush LI, Zandi S, Mitchell A, et al; HALT Pan-Leukemia Gene Panel Consortium. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia [published correction appears in Nature. 2014;508(7496):420]. Nature. 2014;506(7488):328-333.
    • (2014) Nature , vol.506 , Issue.7488 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3
  • 45
    • 84894304555 scopus 로고    scopus 로고
    • Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    • Corces-Zimmerman MR, Hong W-J, Weissman IL, Medeiros BC, Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci USA. 2014;111(7):2548-2553.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.7 , pp. 2548-2553
    • Corces-Zimmerman, M.R.1    Hong, W.-J.2    Weissman, I.L.3    Medeiros, B.C.4    Majeti, R.5
  • 46
    • 84865827060 scopus 로고    scopus 로고
    • Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
    • Jan M, Snyder TM, Corces-Zimmerman MR, et al. Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med. 2012;4(149):149ra118.
    • (2012) Sci Transl Med , vol.4 , Issue.149 , pp. 149ra118
    • Jan, M.1    Snyder, T.M.2    Corces-Zimmerman, M.R.3
  • 47
    • 84959347439 scopus 로고    scopus 로고
    • Clonal dynamics in a single AML case tracked for 9 years reveals the complexity of leukemia progression
    • Kim T, Yoshida K, Kim YK, et al. Clonal dynamics in a single AML case tracked for 9 years reveals the complexity of leukemia progression. Leukemia. 2016;30(2):295-302.
    • (2016) Leukemia , vol.30 , Issue.2 , pp. 295-302
    • Kim, T.1    Yoshida, K.2    Kim, Y.K.3
  • 48
    • 76349107156 scopus 로고    scopus 로고
    • Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia
    • Carella AM, Garuti A, Cirmena G, et al. Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia. Leuk Lymphoma. 2010;51(2):275-278.
    • (2010) Leuk Lymphoma , vol.51 , Issue.2 , pp. 275-278
    • Carella, A.M.1    Garuti, A.2    Cirmena, G.3
  • 49
    • 37049003546 scopus 로고    scopus 로고
    • Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors
    • Cortes J, Jabbour E, Kantarjian H, et al. Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors. Blood. 2007;110(12):4005-4011.
    • (2007) Blood , vol.110 , Issue.12 , pp. 4005-4011
    • Cortes, J.1    Jabbour, E.2    Kantarjian, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.