Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis

Cell

Volumn 168, Issue 6, 2017, Pages 1000-1014.e15

  Suzuki, Hiroshi I ^a   Young, Richard A ^a,b   Sharp, Phillip A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Brd4; broad H3K4me3 domain; cancer; DGCR8; Drosha; microRNA; super enhancer

Indexed keywords

4 (4 CHLOROPHENYL) 2,3,9 TRIMETHYL 6H THIENO[3,2 F][1,2,4]TRIAZOLO[4,3 A][1,4]DIAZEPINE 6 ACETIC ACID TERT BUTYL ESTER; CAS9 PROTEIN; CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; CRISPR ASSOCIATED PROTEIN; HISTONE H3; LYSINE; MESSENGER RNA; MICRORNA; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DGCR8; TRANSCRIPTION FACTOR DROSHA; UNCLASSIFIED DRUG; (+)-JQ1 COMPOUND; AZEPINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL SPECIFICITY; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; ENHANCER REGION; GENE EXPRESSION; GENE FUNCTION; GENE REGULATORY NETWORK; GENETIC CONSERVATION; HISTONE METHYLATION; IN VITRO STUDY; MALIGNANT NEOPLASM; MOLECULAR BIOLOGY; MOUSE EMBRYONIC STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA PROCESSING; RNA STABILITY; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION; ANIMAL; ANTIBODY SPECIFICITY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HISTONE CODE; HUMAN; META ANALYSIS; METABOLISM; MOUSE; NEOPLASM;

ANIMALS; AZEPINES; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; HISTONE CODE; HUMANS; MICE; MICRORNAS; NEOPLASMS; ORGAN SPECIFICITY; RNA PROCESSING, POST-TRANSCRIPTIONAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRIAZOLES;

EID: 85014857159     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.02.015     Document Type: Article

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