IL-2 modulates the TCR signaling threshold for CD8 but not CD4 T cell proliferation on a single-cell level

Journal of Immunology

Volumn 198, Issue 6, 2017, Pages 2445-2456

  Au Yeung, Byron B ^a   Smith, Geoffrey Alexander ^b   Mueller, James L ^a   Heyn, Cheryl S ^a   Jaszczak, Rebecca Garrett ^b   Weiss, Arthur ^a,b   Zikherman, Julie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; MYC PROTEIN; NUCLEAR RECEPTOR NUR77; T LYMPHOCYTE RECEPTOR; GREEN FLUORESCENT PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; NR4A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CLONAL VARIATION; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MALE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOLOGICAL MODEL; C3H MOUSE; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; COMPARATIVE STUDY; GENETICS; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; SINGLE CELL ANALYSIS; TRANSGENIC MOUSE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; GREEN FLUORESCENT PROTEINS; IMMUNOMODULATION; INTERLEUKIN-2; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, IMMUNOLOGICAL; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; RECEPTOR CROSS-TALK; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS;

EID: 85014682731     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1601453     Document Type: Article

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