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Volumn 532, Issue 7599, 2016, Pages 389-393

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 1; GLYCOGEN SYNTHASE KINASE 3; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MYC PROTEIN; TRANSCRIPTION FACTOR FKHR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; MYC PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

EID: 84964527036     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17442     Document Type: Article
Times cited : (215)

References (30)
  • 1
    • 84895550640 scopus 로고    scopus 로고
    • Polarised cells, polarised views: Asymmetric cell division in hematopoietic cells
    • Pham, K., Sacirbegovic, F. & Russell, S. M. Polarised cells, polarised views: asymmetric cell division in hematopoietic cells. Front. Immunol. 5, (2014)
    • (2014) Front. Immunol. , pp. 5
    • Pham, K.1    Sacirbegovic, F.2    Russell, S.M.3
  • 2
    • 33947730608 scopus 로고    scopus 로고
    • Asymmetric T lymphocyte division in the initiation of adaptive immune responses
    • Chang, J. T. et al. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 315, 1687-1691 (2007).
    • (2007) Science , vol.315 , pp. 1687-1691
    • Chang, J.T.1
  • 3
    • 84255199079 scopus 로고    scopus 로고
    • The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
    • Wang, R. et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 35, 871-882 (2011).
    • (2011) Immunity , vol.35 , pp. 871-882
    • Wang, R.1
  • 4
    • 42249101428 scopus 로고    scopus 로고
    • Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse
    • Huang, C. Y., Bredemeyer, A. L., Walker, L. M., Bassing, C. H. & Sleckman, B. P. Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. Eur. J. Immunol. 38, 342-349 (2008).
    • (2008) Eur. J. Immunol. , vol.38 , pp. 342-349
    • Huang, C.Y.1    Bredemeyer, A.L.2    Walker, L.M.3    Bassing, C.H.4    Sleckman, B.P.5
  • 5
    • 33644556146 scopus 로고    scopus 로고
    • Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
    • Colombetti, S., Basso, V., Mueller, D. L. & Mondino, A. Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin. J. Immunol. 176, 2730-2738 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 2730-2738
    • Colombetti, S.1    Basso, V.2    Mueller, D.L.3    Mondino, A.4
  • 6
    • 45849105156 scopus 로고    scopus 로고
    • The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
    • Sancak, Y. et al. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320, 1496-1501 (2008).
    • (2008) Science , vol.320 , pp. 1496-1501
    • Sancak, Y.1
  • 7
    • 77953775808 scopus 로고    scopus 로고
    • Control of immune response by amino acid metabolism
    • Grohmann, U. & Bronte, V. Control of immune response by amino acid metabolism. Immunol. Rev. 236, 243-264 (2010).
    • (2010) Immunol. Rev. , vol.236 , pp. 243-264
    • Grohmann, U.1    Bronte, V.2
  • 8
    • 56249147509 scopus 로고    scopus 로고
    • Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
    • Choo, A. Y., Yoon, S. O., Kim, S. G., Roux, P. P. & Blenis, J. Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation. Proc. Natl Acad. Sci. USA 105, 17414-17419 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 17414-17419
    • Choo, A.Y.1    Yoon, S.O.2    Kim, S.G.3    Roux, P.P.4    Blenis, J.5
  • 9
    • 79958696694 scopus 로고    scopus 로고
    • The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling
    • Hsu, P. P. et al. The mTOR-Regulated Phosphoproteome Reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-1322 (2011).
    • (2011) Science , vol.332 , pp. 1317-1322
    • Hsu, P.P.1
  • 10
    • 62049086102 scopus 로고    scopus 로고
    • An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance
    • Ouyang, W., Beckett, O., Flavell, R. A. & Li, M. O. An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. Immunity 30, 358-371 (2009).
    • (2009) Immunity , vol.30 , pp. 358-371
    • Ouyang, W.1    Beckett, O.2    Flavell, R.A.3    Li, M.O.4
  • 11
    • 84887441485 scopus 로고    scopus 로고
    • Antagonism between FOXO and Myc regulates cellular powerhouse
    • Peck, B., Ferber, E. C. & Schulze, A. Antagonism between FOXO and Myc regulates cellular powerhouse. Front. Oncol. 3, (2013)
    • (2013) Front. Oncol. , pp. 3
    • Peck, B.1    Ferber, E.C.2    Schulze, A.3
  • 12
    • 80051997049 scopus 로고    scopus 로고
    • The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function
    • Yang, K., Neale, G., Green, D. R., He, W. & Chi, H. The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function. Nature Immunol. 12, 888-897 (2011).
    • (2011) Nature Immunol. , vol.12 , pp. 888-897
    • Yang, K.1    Neale, G.2    Green, D.R.3    He, W.4    Chi, H.5
  • 13
    • 33845919326 scopus 로고    scopus 로고
    • The ins and outs of MYC regulation by posttranslational mechanisms
    • Vervoorts, J., Luscher-Firzlaff, J. & Luscher, B. The ins and outs of MYC regulation by posttranslational mechanisms. J. Biol. Chem. 281, 34725-34729 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 34725-34729
    • Vervoorts, J.1    Luscher-Firzlaff, J.2    Luscher, B.3
  • 14
    • 13944252067 scopus 로고    scopus 로고
    • The life cycle of C-myc: From synthesis to degradation
    • Sears, R. C. The life cycle of C-myc: from synthesis to degradation. Cell Cycle 3, 1133-1137 (2004).
    • (2004) Cell Cycle , vol.3 , pp. 1133-1137
    • Sears, R.C.1
  • 15
    • 57749088701 scopus 로고    scopus 로고
    • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
    • Wise, D. R. et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc. Natl Acad. Sci. USA 105, 18782-18787 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 18782-18787
    • Wise, D.R.1
  • 16
    • 84866562625 scopus 로고    scopus 로고
    • Metabolic checkpoints in activated T cells
    • Wang, R. & Green, D. R. Metabolic checkpoints in activated T cells. Nature Immunol. 13, 907-915 (2012).
    • (2012) Nature Immunol. , vol.13 , pp. 907-915
    • Wang, R.1    Green, D.R.2
  • 17
    • 84863202384 scopus 로고    scopus 로고
    • Molecular mechanisms of metabolic reprogramming in proliferating cells: Implications for T-cell-mediated immunity
    • Marelli-Berg, F. M., Fu, H. & Mauro, C. Molecular mechanisms of metabolic reprogramming in proliferating cells: implications for T-cell-mediated immunity. Immunology 136, 363-369 (2012).
    • (2012) Immunology , vol.136 , pp. 363-369
    • Marelli-Berg, F.M.1    Fu, H.2    Mauro, C.3
  • 18
    • 84856183120 scopus 로고    scopus 로고
    • + T cell memory development
    • + T cell memory development. Immunity 36, 68-78 (2012).
    • (2012) Immunity , vol.36 , pp. 68-78
    • Van Der-Windt, G.J.1
  • 19
    • 84865285455 scopus 로고    scopus 로고
    • Metabolic switching and fuel choice during T-cell differentiation and memory development
    • van der Windt, G. J. & Pearce, E. L. Metabolic switching and fuel choice during T-cell differentiation and memory development. Immunol. Rev. 249, 27-42 (2012).
    • (2012) Immunol. Rev. , vol.249 , pp. 27-42
    • Van Der-Windt, G.J.1    Pearce, E.L.2
  • 20
    • 84927732079 scopus 로고    scopus 로고
    • Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness
    • Katajisto, P. et al. Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science 348, 340-343 (2015).
    • (2015) Science , vol.348 , pp. 340-343
    • Katajisto, P.1
  • 21
    • 84897059078 scopus 로고    scopus 로고
    • + T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses
    • + T lymphocyte fates during adaptive immunity revealed by single-cell gene-expression analyses. Nature Immunol. 15, 365-372 (2014).
    • (2014) Nature Immunol. , vol.15 , pp. 365-372
    • Arsenio, J.1
  • 22
    • 37049013109 scopus 로고    scopus 로고
    • + T cell precursor can develop into diverse effector and memory subsets
    • + T cell precursor can develop into diverse effector and memory subsets. Immunity 27, 985-997 (2007).
    • (2007) Immunity , vol.27 , pp. 985-997
    • Stemberger, C.1
  • 23
    • 53349143662 scopus 로고    scopus 로고
    • Dissecting T cell lineage relationships by cellular barcoding
    • Schepers, K. et al. Dissecting T cell lineage relationships by cellular barcoding. J. Exp. Med. 205, 2309-2318 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2309-2318
    • Schepers, K.1
  • 24
    • 58849126149 scopus 로고    scopus 로고
    • + T cells that had developed an effector phenotype
    • + T cells that had developed an effector phenotype. Science 323, 505-509 (2009).
    • (2009) Science , vol.323 , pp. 505-509
    • Bannard, O.1    Kraman, M.2    Fearon, D.T.3
  • 25
    • 41149158001 scopus 로고    scopus 로고
    • Memory CD4 T cells emerge from effector T-cell progenitors
    • 10.1038/nature06672
    • Harrington, L. E., Janowski, K. M., Oliver, J. R., Zajac, A. J. & Weaver, C. T. Memory CD4 T cells emerge from effector T-cell progenitors. Nature 452, 356-360 10.1038/nature06672 (2008).
    • (2008) Nature , vol.452 , pp. 356-360
    • Harrington, L.E.1    Janowski, K.M.2    Oliver, J.R.3    Zajac, A.J.4    Weaver, C.T.5
  • 27
    • 70350728803 scopus 로고    scopus 로고
    • MYC-induced cancer cell energy metabolism and therapeutic opportunities
    • Dang, C. V., Le, A. & Gao, P. MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin. Cancer Res. 15, 6479-6483 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , pp. 6479-6483
    • Dang, C.V.1    Le, A.2    Gao, P.3
  • 28
    • 64749116346 scopus 로고    scopus 로고
    • C-Myc suppression of MIR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
    • Gao, P. et al. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458, 762-765 (2009).
    • (2009) Nature , vol.458 , pp. 762-765
    • Gao, P.1
  • 30
    • 67650074206 scopus 로고    scopus 로고
    • MTOR regulates memory CD8 T-cell differentiation
    • Araki, K. et al. mTOR regulates memory CD8 T-cell differentiation. Nature 460, 108-112 (2009).
    • (2009) Nature , vol.460 , pp. 108-112
    • Araki, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.