Small molecule inhibition of Csk alters affinity recognition by T cells

eLife

Volumn 4, Issue AUGUST2015, 2015, Pages

  Manz, Boryana N ^a   Tan, Ying Xim ^a,d   Courtney, Adam H ^a   Rutaganira, Florentine ^a,b   Palmer, Ed ^c   Shokat, Kevan M ^a,b   Weiss, Arthur ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; C TERMINAL SRC KINASE; CD3 ANTIBODY; IMMUNOGLOBULIN G4; OVALBUMIN; PROTEIN KINASE; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; CSK TYROSINE-PROTEIN KINASE; ENZYME INHIBITOR; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL STIMULATION; DEPHOSPHORYLATION; DOWN REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOBLOTTING; MOUSE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; IMMUNOLOGY; METABOLISM;

ANIMALS; CELL PROLIFERATION; ENZYME INHIBITORS; MICE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; T-LYMPHOCYTES;

EID: 84941908111     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.08088     Document Type: Article

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