Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity

Scientific Reports

Volumn 7, Issue , 2017, Pages

  Pi, Huifeng ^a   Li, Min ^a   Tian, Li ^a   Yang, Zhiqi ^a,b   Yu, Zhengping ^a   Zhou, Zhou ^a,c  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b LANZHOU GENERAL HOSPITAL   (China)

^c GUANGXI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; CADMIUM; CATHEPSIN D; CTSD PROTEIN, MOUSE; LAMP1 PROTEIN, MOUSE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; TCFEB PROTEIN, MOUSE;

ANIMAL; AUTOPHAGY; C57BL MOUSE; CELL NUCLEUS; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; LYSOSOME; MALE; METABOLISM; MOUSE; NERVE CELL; ORGANELLE BIOGENESIS; PATHOLOGY; PH; PLASMID; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CADMIUM; CATHEPSIN D; CELL LINE, TUMOR; CELL NUCLEUS; GENE EXPRESSION REGULATION; HYDROGEN-ION CONCENTRATION; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; ORGANELLE BIOGENESIS; PLASMIDS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 85014108413     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep43466     Document Type: Article

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