MiR128 up-regulation correlates with impaired amyloid β(1-42) degradation in monocytes from patients with sporadic Alzheimer's disease

Neurobiology of Aging

Volumn 35, Issue 2, 2014, Pages 345-356

  Tiribuzi, Roberto ^a   Crispoltoni, Lucia ^a   Porcellati, Serena ^a   Di Lullo, Martina ^b   Florenzano, Fulvio ^c   Pirro, Matteo ^a   Bagaglia, Francesco ^a   Kawarai, Toshitaka ^d   Zampolini, Mauro ^e   Orlacchio, Aldo ^a,f   Orlacchio, Antonio ^b,g  

^a UNIVERSITY OF PERUGIA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e Ospedale San Giovanni Battista   (Italy)

^f Fondazione Genitori and Bimbi Sani (GeBiSa)   (Italy)

^g UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Cathepsin B; Lysosomal enzymes; MiR 128; Monocytes; Sporadic Alzheimer's disease; TFEB

Indexed keywords

ALPHA MANNOSIDASE; AMYLOID BETA PROTEIN[1-42]; BETA GALACTOSIDASE; BETA N ACETYLHEXOSAMINIDASE; CATHEPSIN B; CATHEPSIN D; CATHEPSIN S; LYSOSOME ENZYME; MICRORNA; MICRORNA 128; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GAIN OF FUNCTION MUTATION; GENE CONTROL; HUMAN; HUMAN CELL; IN VITRO STUDY; LOSS OF FUNCTION MUTATION; LYMPHOCYTE; MALE; MONOCYTE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UPREGULATION;

CATHEPSIN B; LYSOSOMAL ENZYMES; MIR-128; MONOCYTES; SPORADIC ALZHEIMER'S DISEASE; TFEB;

AGED; ALPHA-MANNOSIDASE; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BETA-GALACTOSIDASE; BETA-N-ACETYLHEXOSAMINIDASES; CATHEPSINS; CELLS, CULTURED; FEMALE; HUMANS; LYMPHOCYTES; LYSOSOMES; MALE; MICRORNAS; MONOCYTES; PEPTIDE FRAGMENTS; PROTEOLYSIS; UP-REGULATION;

EID: 84887243168     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2013.08.003     Document Type: Article

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