Autophagy induction contributes to cadmium toxicity in mesenchymal stem cells via AMPK/FOXO3a/BECN1 signaling

Toxicological Sciences

Volumn 154, Issue 1, 2016, Pages 101-114

  Yang, Min ^a   Pi, Huifeng ^a   Li, Min ^a   Xu, Shangcheng ^a   Zhang, Lei ^a   Xie, Jia ^a   Tian, Li ^a   Tu, Manyu ^a   He, Mindi ^a   Lu, Yonghui ^a   Yu, Zhengping ^a   Zhou, Zhou ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

AMPK; Autophagy; BECN1; Cadmium; FOXO3a; Mesenchymal stem cells

Indexed keywords

AUTOPHAGY RELATED PROTEIN 12; AUTOPHAGY RELATED PROTEIN 5; BECLIN 1; CADMIUM CHLORIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; SERINE; SERINE THREONINE PROTEIN KINASE ULK1; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; BECN1 PROTEIN, MOUSE; CADMIUM; FOXO3 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BONE INJURY; CONTROLLED STUDY; GENE EXPRESSION; GENE SILENCING; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HEAVY METAL POISONING; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; DRUG EFFECTS; MESENCHYMAL STROMA CELL; METABOLISM;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; BECLIN-1; CADMIUM; CELL LINE; FORKHEAD BOX PROTEIN O3; MESENCHYMAL STROMAL CELLS; MICE; SIGNAL TRANSDUCTION;

EID: 85006256537     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfw144     Document Type: Article

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