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Volumn 75, Issue , 2017, Pages 299-307

DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility

(46)  Ambatipudi, Srikant a   Horvath, Steve b   Perrier, Flavie a   Cuenin, Cyrille a   Hernandez Vargas, Hector a   Le Calvez Kelm, Florence a   Durand, Geoffroy a   Byrnes, Graham a   Ferrari, Pietro a   Bouaoun, Liacine a   Sklias, Athena a   Chajes, Véronique a   Overvad, Kim c   Severi, Gianluca d,e,f   Baglietto, Laura d,f   Clavel Chapelon, Françoise d   Kaaks, Rudolf g   Barrdahl, Myrto g   Boeing, Heiner h   Trichopoulou, Antonia i,j   more..


Author keywords

Age acceleration; Biomarkers; Breast cancer; DNA methylation; Epigenomics; Prospective studies

Indexed keywords

CYTOSINE; DNA; ESTROGEN RECEPTOR; GUANINE; PHOSPHATE; PROGESTERONE RECEPTOR;

EID: 85014082011     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2017.01.014     Document Type: Article
Times cited : (139)

References (46)
  • 1
    • 40049094626 scopus 로고    scopus 로고
    • Impact of aging on the biology of breast cancer
    • [1] Benz, C.C., Impact of aging on the biology of breast cancer. Crit Rev Oncol Hematol 66:1 (2008), 65–74.
    • (2008) Crit Rev Oncol Hematol , vol.66 , Issue.1 , pp. 65-74
    • Benz, C.C.1
  • 2
    • 84929991442 scopus 로고    scopus 로고
    • Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin
    • [2] Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., et al. Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science 348:6237 (2015), 880–886.
    • (2015) Science , vol.348 , Issue.6237 , pp. 880-886
    • Martincorena, I.1    Roshan, A.2    Gerstung, M.3    Ellis, P.4    Van Loo, P.5    McLaren, S.6
  • 3
    • 84874963173 scopus 로고    scopus 로고
    • Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges
    • [3] Deelen, J., Beekman, M., Capri, M., Franceschi, C., Slagboom, P.E., Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges. Bioessays 35:4 (2013), 386–396.
    • (2013) Bioessays , vol.35 , Issue.4 , pp. 386-396
    • Deelen, J.1    Beekman, M.2    Capri, M.3    Franceschi, C.4    Slagboom, P.E.5
  • 4
    • 84886111619 scopus 로고    scopus 로고
    • DNA methylation age of human tissues and cell types
    • [4] Horvath, S., DNA methylation age of human tissues and cell types. Genome Biol, 14(10), 2013, R115.
    • (2013) Genome Biol , vol.14 , Issue.10 , pp. R115
    • Horvath, S.1
  • 5
    • 84930738510 scopus 로고    scopus 로고
    • The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936
    • [5] Marioni, R.E., Shah, S., McRae, A.F., Ritchie, S.J., Muniz-Terrera, G., Harris, S.E., et al. The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. Int J Epidemiol 44:4 (2015), 1388–1396.
    • (2015) Int J Epidemiol , vol.44 , Issue.4 , pp. 1388-1396
    • Marioni, R.E.1    Shah, S.2    McRae, A.F.3    Ritchie, S.J.4    Muniz-Terrera, G.5    Harris, S.E.6
  • 6
    • 84955194730 scopus 로고    scopus 로고
    • DNA methylation age is associated with mortality in a longitudinal Danish twin study
    • [6] Christiansen, L., Lenart, A., Tan, Q., Vaupel, J.W., Aviv, A., McGue, M., et al. DNA methylation age is associated with mortality in a longitudinal Danish twin study. Aging Cell 15:1 (2016), 149–154.
    • (2016) Aging Cell , vol.15 , Issue.1 , pp. 149-154
    • Christiansen, L.1    Lenart, A.2    Tan, Q.3    Vaupel, J.W.4    Aviv, A.5    McGue, M.6
  • 7
    • 84975246016 scopus 로고    scopus 로고
    • Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort
    • [7] Perna, L., Zhang, Y., Mons, U., Holleczek, B., Saum, K.U., Brenner, H., Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort. Clin Epigenetics, 8, 2016, 64.
    • (2016) Clin Epigenetics , vol.8 , pp. 64
    • Perna, L.1    Zhang, Y.2    Mons, U.3    Holleczek, B.4    Saum, K.U.5    Brenner, H.6
  • 8
  • 9
    • 84991466905 scopus 로고    scopus 로고
    • DNA methylation-based measures of biological age: meta-analysis predicting time to death
    • [9] Chen, B.H., Marioni, R.E., Colicino, E., Peters, M.J., Ward-Caviness, C.K., Tsai, P.C., et al. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY) 8:9 (2016), 1844–1865.
    • (2016) Aging (Albany NY) , vol.8 , Issue.9 , pp. 1844-1865
    • Chen, B.H.1    Marioni, R.E.2    Colicino, E.3    Peters, M.J.4    Ward-Caviness, C.K.5    Tsai, P.C.6
  • 10
    • 85001610245 scopus 로고    scopus 로고
    • Frailty is associated with the epigenetic clock but not with telomere length in a German cohort
    • [10] Breitling, L.P., Saum, K.U., Perna, L., Schottker, B., Holleczek, B., Brenner, H., Frailty is associated with the epigenetic clock but not with telomere length in a German cohort. Clin Epigenetics, 8, 2016, 21.
    • (2016) Clin Epigenetics , vol.8 , pp. 21
    • Breitling, L.P.1    Saum, K.U.2    Perna, L.3    Schottker, B.4    Holleczek, B.5    Brenner, H.6
  • 11
    • 84957568353 scopus 로고    scopus 로고
    • Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning
    • [11] Levine, M.E., Lu, A.T., Bennett, D.A., Horvath, S., Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning. Aging (Albany NY) 7:12 (2015), 1198–1211.
    • (2015) Aging (Albany NY) , vol.7 , Issue.12 , pp. 1198-1211
    • Levine, M.E.1    Lu, A.T.2    Bennett, D.A.3    Horvath, S.4
  • 12
    • 84962162147 scopus 로고    scopus 로고
    • Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies
    • [12] Simpkin, A.J., Hemani, G., Suderman, M., Gaunt, T.R., Lyttleton, O., McArdle, W.L., et al. Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies. Hum Mol Genet 25:1 (2016), 191–201.
    • (2016) Hum Mol Genet , vol.25 , Issue.1 , pp. 191-201
    • Simpkin, A.J.1    Hemani, G.2    Suderman, M.3    Gaunt, T.R.4    Lyttleton, O.5    McArdle, W.L.6
  • 14
    • 84983086777 scopus 로고    scopus 로고
    • HIV-1 infection accelerates age according to the epigenetic clock
    • [14] Horvath, S., Levine, A.J., HIV-1 infection accelerates age according to the epigenetic clock. J Infect Dis 212:10 (2015), 1563–1573.
    • (2015) J Infect Dis , vol.212 , Issue.10 , pp. 1563-1573
    • Horvath, S.1    Levine, A.J.2
  • 15
    • 85017019815 scopus 로고    scopus 로고
    • Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
    • [15] Horvath, S., Langfelder, P., Kwak, S., Aaronson, J., Rosinski, J., Vogt, T.F., et al. Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels. Aging (Albany NY) 8:7 (2016), 1485–1512.
    • (2016) Aging (Albany NY) , vol.8 , Issue.7 , pp. 1485-1512
    • Horvath, S.1    Langfelder, P.2    Kwak, S.3    Aaronson, J.4    Rosinski, J.5    Vogt, T.F.6
  • 17
    • 84955639438 scopus 로고    scopus 로고
    • Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
    • [17] Zannas, A.S., Arloth, J., Carrillo-Roa, T., Iurato, S., Roh, S., Ressler, K.J., et al. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biol, 16, 2015, 266.
    • (2015) Genome Biol , vol.16 , pp. 266
    • Zannas, A.S.1    Arloth, J.2    Carrillo-Roa, T.3    Iurato, S.4    Roh, S.5    Ressler, K.J.6
  • 19
    • 84957539650 scopus 로고    scopus 로고
    • Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
    • [19] Horvath, S., Ritz, B.R., Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients. Aging (Albany NY) 7:12 (2015), 1130–1142.
    • (2015) Aging (Albany NY) , vol.7 , Issue.12 , pp. 1130-1142
    • Horvath, S.1    Ritz, B.R.2
  • 20
    • 84943372238 scopus 로고    scopus 로고
    • DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative
    • [20] Levine, M.E., Hosgood, H.D., Chen, B., Absher, D., Assimes, T., Horvath, S., DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative. Aging (Albany NY) 7:9 (2015), 690–700.
    • (2015) Aging (Albany NY) , vol.7 , Issue.9 , pp. 690-700
    • Levine, M.E.1    Hosgood, H.D.2    Chen, B.3    Absher, D.4    Assimes, T.5    Horvath, S.6
  • 21
    • 1542725074 scopus 로고    scopus 로고
    • Diet and cancer–the European prospective investigation into cancer and nutrition
    • [21] Bingham, S., Riboli, E., Diet and cancer–the European prospective investigation into cancer and nutrition. Nat Rev Cancer 4:3 (2004), 206–215.
    • (2004) Nat Rev Cancer , vol.4 , Issue.3 , pp. 206-215
    • Bingham, S.1    Riboli, E.2
  • 22
    • 0345700787 scopus 로고    scopus 로고
    • European prospective investigation into cancer and nutrition (EPIC): study populations and data collection
    • [22] Riboli, E., Hunt, K.J., Slimani, N., Ferrari, P., Norat, T., Fahey, M., et al. European prospective investigation into cancer and nutrition (EPIC): study populations and data collection. Public Health Nutr 5:6B (2002), 1113–1124.
    • (2002) Public Health Nutr , vol.5 , Issue.6B , pp. 1113-1124
    • Riboli, E.1    Hunt, K.J.2    Slimani, N.3    Ferrari, P.4    Norat, T.5    Fahey, M.6
  • 24
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • [24] Gentleman, R.C., Carey, V.J., Bates, D.M., Bolstad, B., Dettling, M., Dudoit, S., et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol, 5(10), 2004, R80.
    • (2004) Genome Biol , vol.5 , Issue.10 , pp. R80
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5    Dudoit, S.6
  • 25
    • 84874353239 scopus 로고    scopus 로고
    • Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray
    • [25] Chen, Y.A., Lemire, M., Choufani, S., Butcher, D.T., Grafodatskaya, D., Zanke, B.W., et al. Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray. Epigenetics 8:2 (2013), 203–209.
    • (2013) Epigenetics , vol.8 , Issue.2 , pp. 203-209
    • Chen, Y.A.1    Lemire, M.2    Choufani, S.3    Butcher, D.T.4    Grafodatskaya, D.5    Zanke, B.W.6
  • 26
    • 84872564830 scopus 로고    scopus 로고
    • A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
    • [26] Teschendorff, A.E., Marabita, F., Lechner, M., Bartlett, T., Tegner, J., Gomez-Cabrero, D., et al. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics 29:2 (2013), 189–196.
    • (2013) Bioinformatics , vol.29 , Issue.2 , pp. 189-196
    • Teschendorff, A.E.1    Marabita, F.2    Lechner, M.3    Bartlett, T.4    Tegner, J.5    Gomez-Cabrero, D.6
  • 28
    • 84981165311 scopus 로고    scopus 로고
    • An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
    • [28] Horvath, S., Gurven, M., Levine, M.E., Trumble, B.C., Kaplan, H., Allayee, H., et al. An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Genome Biol, 17(1), 2016, 171.
    • (2016) Genome Biol , vol.17 , Issue.1 , pp. 171
    • Horvath, S.1    Gurven, M.2    Levine, M.E.3    Trumble, B.C.4    Kaplan, H.5    Allayee, H.6
  • 29
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • [29] Esteller, M., Epigenetics in cancer. N Engl J Med 358:11 (2008), 1148–1159.
    • (2008) N Engl J Med , vol.358 , Issue.11 , pp. 1148-1159
    • Esteller, M.1
  • 30
    • 84902547679 scopus 로고    scopus 로고
    • Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch
    • [30] Martin, M., Ancey, P.B., Cros, M.P., Durand, G., Le Calvez-Kelm, F., Hernandez-Vargas, H., et al. Dynamic imbalance between cancer cell subpopulations induced by transforming growth factor beta (TGF-beta) is associated with a DNA methylome switch. BMC Genomics, 15, 2014, 435.
    • (2014) BMC Genomics , vol.15 , pp. 435
    • Martin, M.1    Ancey, P.B.2    Cros, M.P.3    Durand, G.4    Le Calvez-Kelm, F.5    Hernandez-Vargas, H.6
  • 31
    • 80053304450 scopus 로고    scopus 로고
    • High density DNA methylation array with single CpG site resolution
    • [31] Bibikova, M., Barnes, B., Tsan, C., Ho, V., Klotzle, B., Le, J.M., et al. High density DNA methylation array with single CpG site resolution. Genomics 98:4 (2011), 288–295.
    • (2011) Genomics , vol.98 , Issue.4 , pp. 288-295
    • Bibikova, M.1    Barnes, B.2    Tsan, C.3    Ho, V.4    Klotzle, B.5    Le, J.M.6
  • 32
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    • [32] Irizarry, R.A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C., Onyango, P., et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 41:2 (2009), 178–186.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3    Wu, Z.4    Montano, C.5    Onyango, P.6
  • 33
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
    • [33] Sandoval, J., Heyn, H., Moran, S., Serra-Musach, J., Pujana, M.A., Bibikova, M., et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics 6:6 (2011), 692–702.
    • (2011) Epigenetics , vol.6 , Issue.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.2    Moran, S.3    Serra-Musach, J.4    Pujana, M.A.5    Bibikova, M.6
  • 34
    • 77955739991 scopus 로고    scopus 로고
    • Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives
    • [34] Blagosklonny, M.V., Why men age faster but reproduce longer than women: mTOR and evolutionary perspectives. Aging (Albany NY) 2:5 (2010), 265–273.
    • (2010) Aging (Albany NY) , vol.2 , Issue.5 , pp. 265-273
    • Blagosklonny, M.V.1
  • 35
    • 0031012554 scopus 로고    scopus 로고
    • Postmenopausal acceleration of age-related mortality increase
    • [35] Horiuchi, S., Postmenopausal acceleration of age-related mortality increase. J Gerontol A Biol Sci Med Sci 52:1 (1997), B78–B92.
    • (1997) J Gerontol A Biol Sci Med Sci , vol.52 , Issue.1 , pp. B78-B92
    • Horiuchi, S.1
  • 36
  • 37
    • 84872132897 scopus 로고    scopus 로고
    • DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
    • [37] Heyn, H., Carmona, F.J., Gomez, A., Ferreira, H.J., Bell, J.T., Sayols, S., et al. DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker. Carcinogenesis 34:1 (2013), 102–108.
    • (2013) Carcinogenesis , vol.34 , Issue.1 , pp. 102-108
    • Heyn, H.1    Carmona, F.J.2    Gomez, A.3    Ferreira, H.J.4    Bell, J.T.5    Sayols, S.6
  • 38
    • 84912034001 scopus 로고    scopus 로고
    • Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer
    • [38] Severi, G., Southey, M.C., English, D.R., Jung, C.H., Lonie, A., McLean, C., et al. Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer. Breast Cancer Res Treat 148:3 (2014), 665–673.
    • (2014) Breast Cancer Res Treat , vol.148 , Issue.3 , pp. 665-673
    • Severi, G.1    Southey, M.C.2    English, D.R.3    Jung, C.H.4    Lonie, A.5    McLean, C.6
  • 39
    • 84861766439 scopus 로고    scopus 로고
    • DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study
    • [39] Xu, X., Gammon, D.M., Hernandez-Vargas, H., Herceg, Z., Wetmur, G.J., Teitelbaum, L.S., et al. DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study. FASEB J 26 (2012), 2657–2666.
    • (2012) FASEB J , vol.26 , pp. 2657-2666
    • Xu, X.1    Gammon, D.M.2    Hernandez-Vargas, H.3    Herceg, Z.4    Wetmur, G.J.5    Teitelbaum, L.S.6
  • 40
    • 78650352867 scopus 로고    scopus 로고
    • Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
    • [40] Wallace, K., Grau, M.V., Levine, A.J., Shen, L., Hamdan, R., Chen, X., et al. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 3:12 (2010), 1552–1564.
    • (2010) Cancer Prev Res (Phila) , vol.3 , Issue.12 , pp. 1552-1564
    • Wallace, K.1    Grau, M.V.2    Levine, A.J.3    Shen, L.4    Hamdan, R.5    Chen, X.6
  • 41
    • 84901637593 scopus 로고    scopus 로고
    • Global methylation levels in peripheral blood leukocyte DNA by LUMA and breast cancer: a case-control study in Japanese women
    • [41] Kuchiba, A., Iwasaki, M., Ono, H., Kasuga, Y., Yokoyama, S., Onuma, H., et al. Global methylation levels in peripheral blood leukocyte DNA by LUMA and breast cancer: a case-control study in Japanese women. Br J Cancer 110:11 (2014), 2765–2771.
    • (2014) Br J Cancer , vol.110 , Issue.11 , pp. 2765-2771
    • Kuchiba, A.1    Iwasaki, M.2    Ono, H.3    Kasuga, Y.4    Yokoyama, S.5    Onuma, H.6
  • 42
    • 84938486545 scopus 로고    scopus 로고
    • Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis
    • [42] van Veldhoven, K., Polidoro, S., Baglietto, L., Severi, G., Sacerdote, C., Panico, S., et al. Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis. Clin Epigenetics, 7(1), 2015, 67.
    • (2015) Clin Epigenetics , vol.7 , Issue.1 , pp. 67
    • van Veldhoven, K.1    Polidoro, S.2    Baglietto, L.3    Severi, G.4    Sacerdote, C.5    Panico, S.6
  • 43
    • 0032845215 scopus 로고    scopus 로고
    • Aging, DNA methylation and cancer
    • [43] Issa, J.P., Aging, DNA methylation and cancer. Crit Rev Oncol Hematol 32:1 (1999), 31–43.
    • (1999) Crit Rev Oncol Hematol , vol.32 , Issue.1 , pp. 31-43
    • Issa, J.P.1
  • 44
    • 84908156860 scopus 로고    scopus 로고
    • Does epigenetic drift contribute to age-related increases in breast cancer risk?
    • [44] Langevin, S.M., Pinney, S.M., Leung, Y.K., Ho, S.M., Does epigenetic drift contribute to age-related increases in breast cancer risk?. Epigenomics 6:4 (2014), 367–369.
    • (2014) Epigenomics , vol.6 , Issue.4 , pp. 367-369
    • Langevin, S.M.1    Pinney, S.M.2    Leung, Y.K.3    Ho, S.M.4
  • 45
    • 84892909863 scopus 로고    scopus 로고
    • Aging and epigenetic drift: a vicious cycle
    • [45] Issa, J.P., Aging and epigenetic drift: a vicious cycle. J Clin Invest 124:1 (2014), 24–29.
    • (2014) J Clin Invest , vol.124 , Issue.1 , pp. 24-29
    • Issa, J.P.1
  • 46
    • 84957674001 scopus 로고    scopus 로고
    • Blood epigenetic age may predict cancer incidence and mortality
    • [46] Zheng, Y., Joyce, B.T., Colicino, E., Liu, L., Zhang, W., Dai, Q., et al. Blood epigenetic age may predict cancer incidence and mortality. EBioMedicine 5 (2016), 68–73.
    • (2016) EBioMedicine , vol.5 , pp. 68-73
    • Zheng, Y.1    Joyce, B.T.2    Colicino, E.3    Liu, L.4    Zhang, W.5    Dai, Q.6


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