The MLKL channel in necroptosis is an octamer formed by tetramers in a dyadic process

Molecular and Cellular Biology

Volumn 37, Issue 5, 2017, Pages

  Huang, Deli ^a   Zheng, Xinru ^a   Wang, Zi An ^a   Chen, Xin ^a   He, Wan Ting ^a   Zhang, Yingying ^a   Xu, Jin Gen ^b   Zhao, Hang ^a   Shi, Wenke ^a   Wang, Xin ^a   Zhu, Yongqun ^b   Han, Jiahua ^a  

^a XIAMEN UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Channel; MLKL; Necroptosis; Octamer

Indexed keywords

CATION CHANNEL; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; MUTANT PROTEIN; OLIGOMER; TETRAMER; UNCLASSIFIED DRUG; DISULFIDE; MLKL PROTEIN, HUMAN; MLKL PROTEIN, MOUSE; PROTEIN BINDING; PROTEIN KINASE; TUMOR NECROSIS FACTOR;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; DISULFIDE BOND; MOUSE; NECROPTOSIS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CHEMISTRY; DRUG EFFECTS; HELA CELL LINE; HUMAN; METABOLISM; NECROSIS; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL MEMBRANE; DISULFIDES; HELA CELLS; HUMANS; MICE; MODELS, BIOLOGICAL; NECROSIS; PROTEIN BINDING; PROTEIN KINASES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85013887832     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00497-16     Document Type: Article

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