Raf kinases are essential for phosphate induction of ERK1/2 phosphorylation in hypertrophic chondrocytes and normal endochondral bone development

Journal of Biological Chemistry

Volumn 292, Issue 8, 2017, Pages 3164-3171

  Papaioannou, Garyfallia ^a,b   Petit, Elizabeth T ^a   Liu, Eva S ^a,b,c   Baccarini, Manuela ^d   Pritchard, Catrin ^e   Demay, Marie B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d UNIVERSITY OF VIENNA   (Austria)

^e UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABLATION; BIOMATERIALS; CELL DEATH; ENZYMES; PHOSPHORYLATION;

ENDOCHONDRAL BONE DEVELOPMENT; GROWTH PLATE; HYPERTROPHIC CHONDROCYTES; IMMUNOREACTIVITIES; PROTEIN STABILITY; SKELETAL DEVELOPMENT; VASCULAR INVASION; VASCULARIZATION;

BODY FLUIDS;

A RAF KINASE; B RAF KINASE; C RAF KINASE; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATE; RAF PROTEIN; UNCLASSIFIED DRUG; BRAF PROTEIN, MOUSE; ISOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHONDROCYTE; CONTROLLED STUDY; EMBRYO; ENCHONDRAL OSSIFICATION; EPIPHYSIS PLATE; FEMALE; MALE; MATURATION; MOUSE; NEWBORN; NEWBORN DEATH; NONHUMAN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULARIZATION; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CELL CULTURE; CHONDROGENESIS; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; APOPTOSIS; BONE DEVELOPMENT; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; GROWTH PLATE; MICE, INBRED C57BL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATES; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS A-RAF; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; RAF KINASES;

EID: 85013823972     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.763342     Document Type: Article

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