Acute Phosphate Restriction Impairs Bone Formation and Increases Marrow Adipose Tissue in Growing Mice

Journal of Bone and Mineral Research

Volumn 31, Issue 12, 2016, Pages 2204-2214

  Ko, Frank C ^a,b   Martins, Janaina S ^a,b   Reddy, Pooja ^a   Bragdon, Beth ^c   Hussein, Amira I ^c   Gerstenfeld, Louis C ^c   Demay, Marie B ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BONE HISTOMORPHOMETRY; BONE FAT INTERACTIONS; DISORDERS OF CALCIUM AND PHOSPHATE METABOLISM

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CCAAT ENHANCER BINDING PROTEIN ALPHA; MESSENGER RNA; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATE; PROADIPOCYTE FACTOR 1; PROTEIN; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD9 PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; BONE MORPHOGENETIC PROTEIN;

ADIPOGENESIS; ADIPOSE TISSUE; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW ADIPOSE TISSUE; BONE MARROW STROMA CELL; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DIET RESTRICTION; ENDOCRINE FUNCTION; FEMALE; FOXC2 GENE; GENE; GENE EXPRESSION; GROWTH PLATE; HEY1 GENE; ID1 GENE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; KLF10 GENE; MALE; METAPHYSIS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; PARACRINE SIGNALING; PHENOTYPE; PHOSPHATE INTAKE; PHOSPHATE METABOLISM; VASCULARIZATION; ADIPOCYTE; ANIMAL; BODY COMPOSITION; BONE DEVELOPMENT; DEFICIENCY; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BODY COMPOSITION; BONE MARROW; BONE MORPHOGENETIC PROTEINS; BONE RESORPTION; CELL DIFFERENTIATION; FEMALE; MALE; MESENCHYMAL STROMAL CELLS; MICE; OSTEOBLASTS; OSTEOGENESIS; PHOSPHATES; SIGNAL TRANSDUCTION;

EID: 84996554908     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2891     Document Type: Article

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