Protective effect of a polysaccharide from Anoectochilus roxburghii against carbon tetrachloride-induced acute liver injury in mice

Journal of Ethnopharmacology

Volumn 200, Issue , 2017, Pages 124-135

  Zeng, Biyu ^a,b   Su, Minghua ^a,b   Chen, Qingxi ^a   Chang, Qiang ^a,b   Wang, Wei ^a,b   Li, Huihua ^b  

^a Fujian Agricultural and Forestry University   (China)

^b Fujian Institute of Subtropical Botany   (China)

Author keywords

Acute liver injury; Anoectochilus roxburghii; Carbon tetrachloride; Hepatoprotective effect; Polysaccharide

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CASPASE 3; CATALASE; CYTOCHROME P450 2E1; GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIVER PROTECTIVE AGENT; MACROPHAGE INFLAMMATORY PROTEIN 2; MALONALDEHYDE; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYSACCHARIDE; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; ANTIOXIDANT; PLANT EXTRACT; PROTECTIVE AGENT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOECTOCHILUS ROXBURGHII; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; LIVER HOMOGENATE; LIVER INJURY; LIVER PROTECTION; LIVER TISSUE; MALE; MEDICINAL PLANT; MOUSE; MOUSE MODEL; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; CHEMICAL AND DRUG INDUCED LIVER INJURY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; ORCHIDACEAE; OXIDATIVE STRESS; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CHEMICAL AND DRUG INDUCED LIVER INJURY; MALE; MICE; ORCHIDACEAE; OXIDATIVE STRESS; PLANT EXTRACTS; POLYSACCHARIDES; PROTECTIVE AGENTS;

EID: 85013441232     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2017.02.018     Document Type: Article

References (50)

1. Aldaba-Muruato, L.R., Moreno, M.G., Shibayama, M., Tsutsumi, V., Pablo Muriel, P., Protective effects of allopurinol against acute liver damage and cirrhosis induced by carbon tetrachloride: modulation of NF-κB, cytokine production and oxidative stress. Biochim. Et. Biophys. Acta 1820 (2012), 65–75.
2. Chen, H.X., Zhang, M., Qu, Z.S., Xie, B.J., Antioxidant activities of different fractions of polysaccharide conjugates from green tea (Camellia sinensis). Food Chem. 106 (2008), 559–563.
3. Cui, S.C., Yu, J., Zhang, X.H., Cheng, M.Z., Yang, L.W., Xu, J.Y., Antihyperglycemic and antioxidant activity of water extract from Anoectochilus roxburghii in experimental diabetes. Exp. Toxicol. Pathol. 65 (2013), 485–488.
4. Dong, D.S., Xu, L.N., Yin, L.H., Qi, Y., Peng, J.Y., Naringin prevents carbon tetrachloride-induced acute liver injury in mice. J. Funct. Foods 12 (2015), 179–191.
5. Du, X.M., Sun, N.Y., Hayashi, J., Chen, Y., Sugiura, M., Shoyama, Y., Hepatoprotective and antihyperliposis activities of in vitro cultured Anoectochilus formosanus. Phytother. Ressearch 17 (2003), 30–33.
6. Fan, J.L., Wu, Z.W., Zhao, T.H., Sun, Y., Ye, H., Xu, R.J., Zeng, X.X., Characterization, antioxidant and hepatoprotective activities of polysaccharides from Ilex latifolia Thunb. Carbohydr. Polym. 101 (2014), 990–997.
7. Fan, Y.J., He, X.J., Zhou, S.D., Luo, A.X., He, T., Chun, Z., Composition analysis and antioxidant activity of polysaccharide from Dendrobium denneanum. Int. J. Mol. Sci. 45 (2009), 169–173.
8. Fang, H.L., Wu, J.B., Lin, W.L., Further studies on the hepatoprotective effects of Anoectochilus formosanus. Phytother. Res. 22 (2008), 291–296.
9. Gan, D., Ma, L.P., Jiang, C.X., Wang, M.C., Zeng, X.X., Medium optimization and potential hepatoprotective effect of mycelial polysaccharides from Pholiota dinghuensis Bi against carbon tetrachloride-induced acute liver injury in mice. Food Chem. Toxicol. 50 (2012), 2681–2688.
10. Hanafusa, H., Morikawa, Y., Uehara, T., Kaneto, M., Ono, A., Yamada, H., Ohno, Y., Urushidani, T., Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats. Toxicology 324 (2014), 43–54.
11. Heeba, G.H., Mahmoud, M.E., Therapeutic potential of morin against liver fibrosis in rats: modulation of oxidative stress, cytokine production and nuclear factor kappa B. Environ. Toxicol. Pharmacol. 37 (2014), 662–671.
12. Hsieh, W.T., Tsai, C.T., Wu, J.B., Hsiao, H.B., Yang, L.C., Lin, W.C., Kinsenoside, a high yielding constituent from Anoectochilus formosanus, inhibits carbon tetrachloride induced Kupffer cells mediated liver damage. J. Ethnopharmacol. 135 (2011), 440–449.
13. Jiang, C.X., Xiong, Q.P., Gan, D., Jiao, Y.P., Liu, J., Ma, L.P., Zeng, X.X., Antioxidant activity and potential hepatoprotective effect of polysaccharides from Cyclina sinensis. Carbohydr. Polym. 91 (2013), 262–268.
14. Li, J.W., Liu, Y.F., Fan, L.P., Ai, L.Z., Shan, L., Antioxidant activities of polysaccharides from the fruiting bodies of Zizyphus Jujuba cv. Jinsixiaozao. Carbohydr. Polym. 84 (2011), 390–394.
15. Li, L., Li, Y.M., Liu, Z.L., Zhang, J.G., Liu, Q., Yi, L.T., The renal protective effects of Anoectochilus roxburghii polysaccharose on diabetic mice induced by high-fat diet and streptozotocin. J. Ethnopharmacol. 178 (2016), 58–65.
16. Lin, C.C., Huang, P.C., Lin, J.M., Antioxidant and hepatoprotective effects of Anoectochilus formosanus and Gynostemma pentaphyllum. Am. J. Chin. Med. 28 (2000), 87–96.
17. Lin, J.M., Lin, C.C., Chiu, H.F., Evaluation of the antiinflammatory and liver-protective effects of Anoectochilus formosanus, Ganoderma lucidum and Gynostemma pentaphyllum in rats. Am. J. Chin. Med. 11 (1993), 59–69.
18. Liu, Q., Ha, W., Liu, Z.L., Xu, J., Tian, Y.L., Zhou, X.W., Mu, X.P., 3-Hydroxybutanolide derivatives and flavonoid glucosides from Anoectochilus roxburghii. Phytochem. Lett. 8 (2014), 109–115.
19. Liu, Y.T., Lu, B.N., Peng, J.Y., Hepatoprotective activity of the total flavonoids from Rosa laevigata Michx fruit in mice treated by paracetamol. Food Chem. 125 (2011), 719–725.
20. －△△Ct method. Methods 25 (2001), 402–408.
21. Luedde, T., Schwabe, R.F., NF-κB in the liver-linking injury fibrosis and hepatocellular carcinoma. Nat. Rev. Gastroenterol. Hepatol. 8 (2011), 108–118.
22. Ma, L.P., Gan, D., Wang, M.C., Zhang, Z.J., Jiang, C.X., Zeng, X.X., Optimization of extraction, preliminary characterization and hepatoprotective effects of polysaccharides from Stachys floridana Schuttl. ex Benth. Carbohydr. Polym. 87 (2012), 1390–1398.
23. 4 induced oxidative stress in albino rats. J. Ethnopharmacol. 153 (2014), 744–752.
24. Nada, S.A., Omara, E.A., Abdel-Salam, O.M., Zahran, H.G., Mushroom insoluble polysaccharides prevent carbon tetrachloride-induced hepatotoxicity in rat. Food Chem. Toxicol. 48 (2010), 3184–3188.
25. Reed, J.C., Mechanisms of apoptosis. Am. J. Pathol. 157 (2000), 1415–1430.
26. Rupinder, S.K., Gurpreet, A.K., Manjeet, S., Cell suicide and caspases. Vasc. Pharmacol. 46 (2007), 383–393.
27. Sahin, H., Wasmuth, H.E., Chemokines in tissue fibrosis. Biochim. Biophys. Acta 1832 (2013), 1041–1048.
28. Shao, Q.S., Deng, Y.M., Liu, H.B., Zhang, A.L., Huang, Y.Q., Xu, G.Z., Li, M.Y., Essential oils extraction from Anoectochilus roxburghii using supercritical carbon dioxide and their antioxidant activity. Ind. Crops Prod. 60 (2014), 104–112.
29. Shih, C.C., Wu, Y.W., Lin, W.C., Scavenging of reactive oxygen species and inhibition of the oxidation of low density lipoprotein by the aqueous extraction of Anoectochilus formosanus. Am. J. Chin. Med. 31 (2003), 25–36.
30. Shih, C.C., Wu, Y.W., Hsieh, C.C., Lin, W.C., Effect of Anoectochilus formosanus on fibrosis and regeneration of the liver in rats. Clin. Exp. Pharmacol. Physiol. 31 (2004), 620–625.
31. Shih, C.C., Wu, Y.W., Lin, W.C., Aqueous extract of Anoectochilus formosanus attenuate hepatic fibrosis induced by carbon tetrachloride in rats. Phytomedicine 12 (2005), 453–460.
32. Shim, J.Y., Kim, M.H., Kim, H.D., Ahn, J.Y., Yun, Y.S., Song, J.Y., Protective action of the immunomodulator ginsan against carbon tetrachloride-induced liver injury via control of oxidative stress and the inflammatory response. Toxicol. Appl. Pharmacol. 242 (2010), 318–325.
33. Siu, K.C., Xu, L.J., Chen, X., Wu, J.Y., Molecular properties and antioxidant activities of polysaccharides isolated from alkaline extract of wild Armillaria ostoyae mushrooms. Carbohydr. Polym. 137 (2016), 739–746.
34. Staub, A.M., Removeal of protein-Sevag method. Methods Carbohydr. Chem. 5 (1965), 5–6.
35. Sun, B., Karin, M., NF-κB signaling, liver disease and hepatoprotective agents. Oncogene 27 (2008), 6228–6244.
36. Sun, Y.D., Wang, Z.H., Ye, Q.S., Composition analysis and anti-proliferation activity of polysaccharides from Dendrobium chrysotoxum. Int. J. Biol. Macromol. 62 (2013), 291–295.
37. 4)-induced liver injury in mice. Toxicology 273 (2010), 45–52.
38. Tseng, C.C., Shang, H.F., Wang, L.F., Su, B., Hsu, C.C., Kao, H.Y., Antitumor and immunostimulating effects of Anoectochilus formosanus Hayata. Phytomedicine 13 (2006), 366–370.
39. Wang, H., Wang, P.Z., Sun, X.Q., Luo, Y., Wang, X., Ma, D.L., Wu, J., Cloning and characterization of a novel caspase-10 isoform that activates NF-κB activity. Biochim. Et. Biophys. Acta 1770 (2007), 1528–1537.
40. Wang, L.Q., Xu, N., Zhang, J.J., Zhao, H.J., Lin, L., Jia, S.H., Jia, L., Antihyperlipidemic and hepatoprotective activities of residue polysaccharide from Cordyceps militaris SU-12. Carbohydr. Polym. 131 (2015), 355–362.
41. Wu, H.T., He, X.J., Hong, Y.K., Ma, T., Xu, Y.P., Li, H.H., Chemical characterization of Lycium barbarum polysaccharides and its inhibition against liver oxidative injury. Int. J. Biol. Macromol. 46 (2010), 540–543.
42. Wu, J.B., Lin, W.L., Hsieh, C.C., Ho, H.Y., Tsay, H.S., Lin, W.C., The hepatoprotective activity of kinsenoside from Anoectochilus formosanus. Phytother. Res. 21 (2007), 58–61.
43. Xiao, J., Liong, E.C., Ching, Y.P., Chang, R.C.C., So, K.F., Fung, M.L., Tipoe, G.L., Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. J. Ethnopharmacol. 139 (2012), 462–470.
44. Yang, J.H., Kim, S.C., Kim, K.M., Jang, C.H., Cho, S.S., Kim, S.J., Ku, S.K., Cho, I.J., Ki, S.H., Isorhamnetin attenuates liver fibrosis by inhibiting TGF-β/Smad signaling and relieving oxidative stress. Eur. J. Pharmacol. 783 (2016), 92–102.
45. Yuan, J.F., Zhang, Z.Q., Fan, Z.C., Yang, J.X., Antioxidant effects and cytotoxicity of three purified polysaccharides from Ligusticum chuanxiong Hort. Carbohydr. Polym. 74 (2008), 822–827.
46. Yuan, Y.V., Bone, D.E., Carrington, M.F., Antioxidant activity of dulse (Palmaria palmate) extract evaluated in vitro. Food Chem. 91 (2005), 485–494.
47. Zeng, B.Y., Su, M.H., Chen, Q.X., Chang, Q., Wang, W., Li, H.H., Antioxidant and hepatoprotective activities of polysaccharides from Anoectochilus roxburghii. Carbohydr. Polym. 153 (2016), 391–398.
48. Zhang, J.G., Liu, Q., Liu, Z.L., Li, L., Yi, L.T., Antihyperglycemic activity of Anoectochilus roxburghii polysaccharose in diabetic mice induced by high-fat diet and streptozotocin. J. Ethnopharmacol. 164 (2015), 180–185.
49. Zhang, S., Lu, B.N., Han, X., Xu, L.N., Qi, Y., Yin, L.H., Xu, Y.W., Zhao, Y.Y., Liu, K.X., Peng, J.Y., Protection of the flavonoid fraction from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice. Food Chem. Toxicol. 55 (2013), 60–69.
50. Zhang, Y.H., Cai, J.Y., Ruan, H.L., Pi, H.F., Wu, J.Z., Antihyperglycemic activity of kinsenoside, a high yielding constituent from Anoectochilus roxburghii in streptozotocin diabetic rats. J. Ethnopharmacol. 114 (2007), 141–145.