A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells

Immunity

Volumn 46, Issue 2, 2017, Pages 233-244

  Mondanelli, Giada ^a   Bianchi, Roberta ^a   Pallotta, Maria Teresa ^a   Orabona, Ciriana ^a   Albini, Elisa ^a   Iacono, Alberta ^a   Belladonna, Maria Laura ^a   Vacca, Carmine ^a   Fallarino, Francesca ^a   Macchiarulo, Antonio ^a   Ugel, Stefano ^b   Bronte, Vincenzo ^b   Gevi, Federica ^c   Zolla, Lello ^c   Verhaar, Auke ^d   Peppelenbosch, Maikel ^d   Mazza, Emilia Maria Cristina ^e   Bicciato, Silvio ^e   Laouar, Yasmina ^f   Santambrogio, Laura ^g   Puccetti, Paolo ^a   Volpi, Claudia ^a   Grohmann, Ursula ^a   more..

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY HOSPITAL OF VERONA   (Italy)

^c UNIVERSITY OF TUSCIA   (Italy)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

amino acid metabolism; Arg1; dendritic cell; IDO1; immune regulation; ornithine; polyamine; TGF

Indexed keywords

ARGINASE 1; ARGININE; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 4; PROTEIN TYROSINE KINASE; PUTRESCINE; SPERMIDINE; SPERMINE; TRANSFORMING GROWTH FACTOR BETA; TRYPTOPHAN; ARG1 PROTEIN, MOUSE; ARGINASE; IDO1 PROTEIN, MOUSE; TRANSCRIPTOME;

AMINO ACID METABOLISM; ANIMAL CELL; ARGININE METABOLISM; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; INTRACELLULAR SIGNALING; MALE; MOUSE; MYELOID-DERIVED SUPPRESSOR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRYPTOPHAN METABOLISM; UPREGULATION; ANIMAL; C57BL MOUSE; GENE EXPRESSION PROFILING; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ARGINASE; ARGININE; BLOTTING, WESTERN; DENDRITIC CELLS; FEMALE; GENE EXPRESSION PROFILING; IMMUNE TOLERANCE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TRYPTOPHAN;

EID: 85012926948     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.01.005     Document Type: Article

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