-
1
-
-
0035175577
-
A defect in central tolerance in NOD mice
-
Kishimoto H, Sprent J. A defect in central tolerance in NOD mice. Nat Immunol. 2001; 2: 1025-31.
-
(2001)
Nat Immunol
, vol.2
, pp. 1025-1031
-
-
Kishimoto, H.1
Sprent, J.2
-
2
-
-
0030873325
-
Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region
-
Colucci F, Bergman ML, Penha-Goncalves C, et al. Apoptosis resistance of nonobese diabetic peripheral lymphocytes linked to the Idd5 diabetes susceptibility region. Proc Natl Acad Sci USA. 1997; 94: 8670-4.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8670-8674
-
-
Colucci, F.1
Bergman, M.L.2
Penha-Goncalves, C.3
-
3
-
-
0036644326
-
Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-κB expression and binding to the IL-12 p40 promoter
-
Liu J, Beller D. Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-κB expression and binding to the IL-12 p40 promoter. Immunol. 2002; 169: 581-6.
-
(2002)
Immunol
, vol.169
, pp. 581-586
-
-
Liu, J.1
Beller, D.2
-
4
-
-
0034949349
-
An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice
-
Suarez-Pinzon WL, Mabley JG, Strynadka K, et al. An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice. J Autoimmun. 2001; 16: 449-55.
-
(2001)
J Autoimmun
, vol.16
, pp. 449-455
-
-
Suarez-Pinzon, W.L.1
Mabley, J.G.2
Strynadka, K.3
-
5
-
-
0027173029
-
Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice
-
Serreze DV, Gaskins HR, Leiter EH. Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. J Immunol. 1993; 150: 2534-43.
-
(1993)
J Immunol
, vol.150
, pp. 2534-2543
-
-
Serreze, D.V.1
Gaskins, H.R.2
Leiter, E.H.3
-
6
-
-
7244231007
-
CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice
-
Fallarino F, Bianchi R, Orabona C, et al. CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice. J Exp Med. 2004; 200: 1051-62.
-
(2004)
J Exp Med
, vol.200
, pp. 1051-1062
-
-
Fallarino, F.1
Bianchi, R.2
Orabona, C.3
-
7
-
-
33644784891
-
Transforming growth factor-β and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes
-
Alyanakian MA, Grela F, Aumeunier A, et al. Transforming growth factor-β and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes. Diabetes. 2006; 55: 179-85.
-
(2006)
Diabetes
, vol.55
, pp. 179-185
-
-
Alyanakian, M.A.1
Grela, F.2
Aumeunier, A.3
-
8
-
-
28444494764
-
Infections and autoimmune diseases
-
Bach JF. Infections and autoimmune diseases. J Autoimmun. 2005; 25(Suppl.): 74-80.
-
(2005)
J Autoimmun
, vol.25
, pp. 74-80
-
-
Bach, J.F.1
-
9
-
-
77649239326
-
IDO mediates TLR9-driven protection from experimental autoimmune diabetes
-
Fallarino F, Volpi C, Zelante T, et al. IDO mediates TLR9-driven protection from experimental autoimmune diabetes. J Immunol. 2005; 183: 6303-12.
-
(2005)
J Immunol
, vol.183
, pp. 6303-6312
-
-
Fallarino, F.1
Volpi, C.2
Zelante, T.3
-
10
-
-
15244349785
-
Plasmacytoid dendritic cells in immunity
-
Colonna M, Trinchieri G, Liu YJ. Plasmacytoid dendritic cells in immunity. Nat Immunol. 2004; 5: 1219-26.
-
(2004)
Nat Immunol
, vol.5
, pp. 1219-1226
-
-
Colonna, M.1
Trinchieri, G.2
Liu, Y.J.3
-
11
-
-
77349088003
-
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
-
Swiecki M, Colonna M. Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance. Immunol Rev. 2010; 234: 142-62.
-
(2010)
Immunol Rev
, vol.234
, pp. 142-162
-
-
Swiecki, M.1
Colonna, M.2
-
13
-
-
51349099789
-
Antigen-presentation properties of plasmacytoid dendritic cells
-
Villadangos JA, Young L. Antigen-presentation properties of plasmacytoid dendritic cells. Immunity. 2008; 29: 352-61.
-
(2008)
Immunity
, vol.29
, pp. 352-361
-
-
Villadangos, J.A.1
Young, L.2
-
14
-
-
48749085127
-
Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases
-
Gilliet M, Cao W, Liu YJ. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol. 2008; 8: 594-606.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 594-606
-
-
Gilliet, M.1
Cao, W.2
Liu, Y.J.3
-
15
-
-
68349116068
-
Plasmacytoid dendritic cells in autoimmune diabetes - potential tools for immunotherapy
-
Nikolic T, Welzen-Coppens JM, Leenen PJ, et al. Plasmacytoid dendritic cells in autoimmune diabetes - potential tools for immunotherapy. Immunobiology. 2009; 214: 791-9.
-
(2009)
Immunobiology
, vol.214
, pp. 791-799
-
-
Nikolic, T.1
Welzen-Coppens, J.M.2
Leenen, P.J.3
-
16
-
-
63249126027
-
Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture
-
Allen JS, Pang K, Skowera A, et al. Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture. Diabetes. 2009; 58: 138-45.
-
(2009)
Diabetes
, vol.58
, pp. 138-145
-
-
Allen, J.S.1
Pang, K.2
Skowera, A.3
-
17
-
-
34748835898
-
IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation
-
Puccetti P, Grohmann U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation. Nat Rev Immunol. 2007; 7: 817-23.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 817-823
-
-
Puccetti, P.1
Grohmann, U.2
-
18
-
-
77952508328
-
Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege
-
Huang L, Baban B, Johnson BA 3rd, et al. Dendritic cells, indoleamine 2, 3 dioxygenase and acquired immune privilege. Int Rev Immunol. 2010; 29: 133-55.
-
(2010)
Int Rev Immunol
, vol.29
, pp. 133-155
-
-
Huang, L.1
Baban, B.2
Johnson III, B.A.3
-
19
-
-
0037815119
-
A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
-
Grohmann U, Fallarino F, Bianchi R, et al. A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice. J Exp Med. 2003; 198: 153-60.
-
(2003)
J Exp Med
, vol.198
, pp. 153-160
-
-
Grohmann, U.1
Fallarino, F.2
Bianchi, R.3
-
20
-
-
80052020183
-
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
-
Pallotta MT, Orabona C, Volpi C, et al. Indoleamine 2, 3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol. 2011; 12: 870-8.
-
(2011)
Nat Immunol
, vol.12
, pp. 870-878
-
-
Pallotta, M.T.1
Orabona, C.2
Volpi, C.3
-
21
-
-
84870476787
-
Different partners, opposite outcomes: a new perspective of the immunobiology of indoleamine 2,3-dioxygenase
-
Orabona C, Pallotta MT, Grohmann U. Different partners, opposite outcomes: a new perspective of the immunobiology of indoleamine 2, 3-dioxygenase. Mol Med. 2012; 18: 834-42.
-
(2012)
Mol Med
, vol.18
, pp. 834-842
-
-
Orabona, C.1
Pallotta, M.T.2
Grohmann, U.3
-
22
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann U, Orabona C, Fallarino F, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol. 2002; 3: 1097-101.
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
-
23
-
-
9244231842
-
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86
-
Orabona C, Grohmann U, Belladonna ML, et al. CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86. Nat Immunol. 2004; 5: 1134-42.
-
(2004)
Nat Immunol
, vol.5
, pp. 1134-1142
-
-
Orabona, C.1
Grohmann, U.2
Belladonna, M.L.3
-
24
-
-
58549107152
-
SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis
-
Orabona C, Pallotta MT, Volpi C, et al. SOCS3 drives proteasomal degradation of indoleamine 2, 3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis. Proc Natl Acad Sci USA. 2008; 105: 20828-33.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20828-20833
-
-
Orabona, C.1
Pallotta, M.T.2
Volpi, C.3
-
25
-
-
34249725559
-
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
-
Grohmann U, Volpi C, Fallarino F, et al. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat Med. 2007; 13: 579-86.
-
(2007)
Nat Med
, vol.13
, pp. 579-586
-
-
Grohmann, U.1
Volpi, C.2
Fallarino, F.3
-
26
-
-
54049130424
-
Cutting edge: autocrine TGF-β sustains default tolerogenesis by IDO-competent dendritic cells
-
Belladonna ML, Volpi C, Bianchi R, et al. Cutting edge: autocrine TGF-β sustains default tolerogenesis by IDO-competent dendritic cells. J Immunol. 2008; 181: 5194-8.
-
(2008)
J Immunol
, vol.181
, pp. 5194-5198
-
-
Belladonna, M.L.1
Volpi, C.2
Bianchi, R.3
-
27
-
-
38049115134
-
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
-
Romani L, Fallarino F, De Luca A, et al. Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature. 2008; 451: 211-5.
-
(2008)
Nature
, vol.451
, pp. 211-215
-
-
Romani, L.1
Fallarino, F.2
De Luca, A.3
-
28
-
-
84878707549
-
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway
-
Volpi C, Fallarino F, Pallotta MT, et al. High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. Nat Commun. 2013; 4: 1852.
-
(2013)
Nat Commun
, vol.4
, pp. 1852
-
-
Volpi, C.1
Fallarino, F.2
Pallotta, M.T.3
-
29
-
-
16244408626
-
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
-
Muller AJ, DuHadaway JB, Donover PS, et al. Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat Med. 2005; 11: 312-9.
-
(2005)
Nat Med
, vol.11
, pp. 312-319
-
-
Muller, A.J.1
DuHadaway, J.B.2
Donover, P.S.3
-
30
-
-
0042930935
-
Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation
-
Grohmann U, Bianchi R, Orabona C, et al. Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation. J Immunol. 2003; 171: 2581-7.
-
(2003)
J Immunol
, vol.171
, pp. 2581-2587
-
-
Grohmann, U.1
Bianchi, R.2
Orabona, C.3
-
32
-
-
66549106623
-
The aryl hydrocarbon receptor: a perspective on potential roles in the immune system
-
Stevens EA, Mezrich JD, Bradfield CA. The aryl hydrocarbon receptor: a perspective on potential roles in the immune system. Immunology. 2009; 127: 299-311.
-
(2009)
Immunology
, vol.127
, pp. 299-311
-
-
Stevens, E.A.1
Mezrich, J.D.2
Bradfield, C.A.3
-
33
-
-
84873318096
-
The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response
-
Quintana FJ. The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response. Immunology. 2013; 138: 183-9.
-
(2013)
Immunology
, vol.138
, pp. 183-189
-
-
Quintana, F.J.1
-
34
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
Opitz CA, Litzenburger UM, Sahm F, et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature. 2011; 478: 197-203.
-
(2011)
Nature
, vol.478
, pp. 197-203
-
-
Opitz, C.A.1
Litzenburger, U.M.2
Sahm, F.3
-
35
-
-
78649880396
-
An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
-
Mezrich JD, Fechner JH, Zhang X, et al. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. J Immunol. 2010; 185: 3190-8.
-
(2010)
J Immunol
, vol.185
, pp. 3190-3198
-
-
Mezrich, J.D.1
Fechner, J.H.2
Zhang, X.3
-
36
-
-
84883704338
-
The regulation of immune responses by DC derived type I IFN
-
Ng D, Gommerman JL. The regulation of immune responses by DC derived type I IFN. Front Immunol. 2013; 4: 94.
-
(2013)
Front Immunol
, vol.4
, pp. 94
-
-
Ng, D.1
Gommerman, J.L.2
-
37
-
-
50449087345
-
Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice
-
Li Q, Xu B, Michie SA, et al. Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci USA. 2008; 105: 12439-44.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12439-12444
-
-
Li, Q.1
Xu, B.2
Michie, S.A.3
-
38
-
-
60649100625
-
TGF-β and kynurenines as the key to infectious tolerance
-
Belladonna ML, Orabona C, Grohmann U, et al. TGF-β and kynurenines as the key to infectious tolerance. Trends Mol Med. 2009; 15: 41-9.
-
(2009)
Trends Mol Med
, vol.15
, pp. 41-49
-
-
Belladonna, M.L.1
Orabona, C.2
Grohmann, U.3
-
39
-
-
2342464085
-
The two NF-κB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 2004; 25: 280-8.
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
40
-
-
0025944659
-
Relationship between interferon-γ, indoleamine 2,3-dioxygenase, and tryptophan catabolism
-
Taylor MW, Feng GS. Relationship between interferon-γ, indoleamine 2, 3-dioxygenase, and tryptophan catabolism. FASEB J. 1991; 5: 2516-22.
-
(1991)
FASEB J
, vol.5
, pp. 2516-2522
-
-
Taylor, M.W.1
Feng, G.S.2
-
41
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science. 1998; 281: 1191-3.
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
-
42
-
-
5044220930
-
IDO expression by dendritic cells: tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol. 2004; 4: 762-74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
43
-
-
27644587079
-
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
-
Platten M, Ho PP, Youssef S, et al. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science. 2005; 310: 850-5.
-
(2005)
Science
, vol.310
, pp. 850-855
-
-
Platten, M.1
Ho, P.P.2
Youssef, S.3
-
44
-
-
78650852553
-
Induction of kidney allograft tolerance by soluble CD83 associated with prevalence of tolerogenic dendritic cells and indoleamine 2,3-dioxygenase
-
Lan Z, Ge W, Arp J, et al. Induction of kidney allograft tolerance by soluble CD83 associated with prevalence of tolerogenic dendritic cells and indoleamine 2, 3-dioxygenase. Transplantation. 2010; 90: 1286-93.
-
(2010)
Transplantation
, vol.90
, pp. 1286-1293
-
-
Lan, Z.1
Ge, W.2
Arp, J.3
-
45
-
-
79956004948
-
+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival
-
+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 2011; 52: 2640-8.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 2640-2648
-
-
Zaher, S.S.1
Germain, C.2
Fu, H.3
-
46
-
-
34249678653
-
TGFβ signalling in control of T-cell-mediated self-reactivity
-
Rubtsov YP, Rudensky AY. TGFβ signalling in control of T-cell-mediated self-reactivity. Nat Rev Immunol. 2007; 7: 443-53.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 443-453
-
-
Rubtsov, Y.P.1
Rudensky, A.Y.2
-
47
-
-
0031423760
-
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD
-
Delovitch TL, Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity. 1997; 7: 727-38.
-
(1997)
Immunity
, vol.7
, pp. 727-738
-
-
Delovitch, T.L.1
Singh, B.2
-
48
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: as good as it gets?
-
Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: as good as it gets? Nat Med. 1999; 5: 601-4.
-
(1999)
Nat Med
, vol.5
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
49
-
-
0036152560
-
T-cell education in autoimmune diabetes: teachers and students
-
Rosmalen JG, van Ewijk W, Leenen PJ. T-cell education in autoimmune diabetes: teachers and students. Trends Immunol. 2002; 23: 40-6.
-
(2002)
Trends Immunol
, vol.23
, pp. 40-46
-
-
Rosmalen, J.G.1
van Ewijk, W.2
Leenen, P.J.3
-
50
-
-
0035424898
-
Dendritic cells from nonobese diabetic mice exhibit a defect in NF-κB regulation due to a hyperactive IκB kinase
-
Weaver DJ Jr, Poligone B, Bui T, et al. Dendritic cells from nonobese diabetic mice exhibit a defect in NF-κB regulation due to a hyperactive IκB kinase. J Immunol. 2001; 167: 1461-8.
-
(2001)
J Immunol
, vol.167
, pp. 1461-1468
-
-
Weaver Jr., D.J.1
Poligone, B.2
Bui, T.3
-
51
-
-
2942746324
-
Increased NF-κB activity in B cells and bone marrow-derived dendritic cells from NOD mice
-
Wheat W, Kupfer R, Gutches DG, et al. Increased NF-κB activity in B cells and bone marrow-derived dendritic cells from NOD mice. Eur J Immunol. 2004; 34: 1395-404.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1395-1404
-
-
Wheat, W.1
Kupfer, R.2
Gutches, D.G.3
-
52
-
-
38449111402
-
The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
-
Saxena V, Ondr JK, Magnusen AF, et al. The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J Immunol. 2007; 179: 5041-53.
-
(2007)
J Immunol
, vol.179
, pp. 5041-5053
-
-
Saxena, V.1
Ondr, J.K.2
Magnusen, A.F.3
-
53
-
-
0035995944
-
Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes
-
Alexander AM, Crawford M, Bertera S, et al. Indoleamine 2, 3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes. 2002; 51: 356-65.
-
(2002)
Diabetes
, vol.51
, pp. 356-365
-
-
Alexander, A.M.1
Crawford, M.2
Bertera, S.3
-
54
-
-
0036849492
-
Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse
-
Sobel DO, Han J, Williams J, et al. Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse. J Autoimmun. 2002; 19: 129-37.
-
(2002)
J Autoimmun
, vol.19
, pp. 129-137
-
-
Sobel, D.O.1
Han, J.2
Williams, J.3
|