HIV-1 recruits UPF1 but excludes UPF2 to promote nucleocytoplasmic export of the genomic RNA

Biomolecules

Volumn 5, Issue 4, 2015, Pages 2808-2839

  Ajamian, Lara ^a,b   Abel, Karen ^a,b   Rao, Shringar ^a,b   Vyboh, Kishanda ^a,b   García de Gracia, Francisco ^c   Soto Rifo, Ricardo ^c   Kulozik, Andreas E ^d,e   Gehring, Niels H ^f   Mouland, Andrew J ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF CHILE   (Chile)

^d Hematology and Immunology ^*  (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f UNIVERSITY OF COLOGNE   (Germany)

Author keywords

HIV 1; Nonsense mediated decay; Nuclear RNA export; Ribonucleoprotein; UPF1; Viral evasion

Indexed keywords

EXPORTIN 1; GAG PROTEIN; GENOMIC RNA; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; ISOPROTEIN; PEPTIDES AND PROTEINS; PROTEIN P62; REV PROTEIN; UNCLASSIFIED DRUG; UPFRAMESHIFT PROTEIN 1; CELL RECEPTOR; DDX3X PROTEIN, HUMAN; DEAD BOX PROTEIN; EXPORTIN 1 PROTEIN; KARYOPHERIN; MEMBRANE PROTEIN; NUCLEAR PORE PROTEIN P62; NUCLEOPORIN; PROTEIN BINDING; RNA BINDING PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UPF1 PROTEIN, HUMAN; UPF2 PROTEIN, HUMAN; UPF3A PROTEIN, HUMAN; VIRUS RNA;

ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOFLUORESCENCE TEST; MOLECULAR DOCKING; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; WESTERN BLOTTING; ACTIVE TRANSPORT; CELL NUCLEUS; HELA CELL LINE; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS RELEASE; VIRUS REPLICATION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; DEAD-BOX RNA HELICASES; HELA CELLS; HIV-1; HUMANS; KARYOPHERINS; MEMBRANE GLYCOPROTEINS; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; RNA, VIRAL; RNA-BINDING PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; VIRUS RELEASE; VIRUS REPLICATION;

EID: 85012088619     PISSN: None     EISSN: 2218273X     Source Type: Journal    
DOI: 10.3390/biom5042808     Document Type: Article

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