Vitamin D Metabolite, 25-Hydroxyvitamin D, Regulates Lipid Metabolism by Inducing Degradation of SREBP/SCAP

Cell Chemical Biology

Volumn 24, Issue 2, 2017, Pages 207-217

  Asano, Lisa ^a,b   Watanabe, Mizuki ^a,b   Ryoden, Yuta ^b   Usuda, Kousuke ^c   Yamaguchi, Takuya ^c   Khambu, Bilon ^a   Takashima, Megumi ^a   Sato, Shin ichi ^a   Sakai, Juro ^d,e   Nagasawa, Kazuo ^c,f   Uesugi, Motonari ^a,b,f  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

SREBP; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; MESSENGER RNA; PROTEIN; SREBP CLEAVTHE AGE ACTIVATING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; 25-HYDROXYVITAMIN D; MEMBRANE PROTEIN; SIGNAL PEPTIDE; SREBP CLEAVAGE-ACTIVATING PROTEIN; VITAMIN D;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE TARGETING; LIPID METABOLISM; METABOLIC REGULATION; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCREENING; VITAMIN SUPPLEMENTATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; CHO CELL LINE; CONFORMATION; CRICETULUS; DOSE RESPONSE; DRUG EFFECT; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELLS, CULTURED; CHO CELLS; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; MEMBRANE PROTEINS; MOLECULAR CONFORMATION; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN D;

EID: 85010874849     PISSN: 24519456     EISSN: 24519448     Source Type: Journal    
DOI: 10.1016/j.chembiol.2016.12.017     Document Type: Article

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