-
1
-
-
84945574356
-
Progresses towards safe and efficient gene therapy vectors
-
Chira S, Jackson CS, Oprea I, et al.: Progresses towards safe and efficient gene therapy vectors. Oncotarget. 2015; 6(31): 30675-703.
-
(2015)
Oncotarget
, vol.6
, Issue.31
, pp. 30675-30703
-
-
Chira, S.1
Jackson, C.S.2
Oprea, I.3
-
2
-
-
0028963221
-
In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma
-
Clayman GL, el-Naggar AK, Roth JA, et al.: In vivo molecular therapy with p53 adenovirus for microscopic residual head and neck squamous carcinoma. Cancer Res. 1995; 55(1): 1-6.
-
(1995)
Cancer Res
, vol.55
, Issue.1
, pp. 1-6
-
-
Clayman, G.L.1
el-Naggar, A.K.2
Roth, J.A.3
-
3
-
-
0028231586
-
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wildtype p53 gene
-
Fujiwara T, Grimm EA, Mukhopadhyay T, et al.: Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wildtype p53 gene. Cancer Res. 1994; 54(9): 2287-91.
-
(1994)
Cancer Res
, vol.54
, Issue.9
, pp. 2287-2291
-
-
Fujiwara, T.1
Grimm, E.A.2
Mukhopadhyay, T.3
-
4
-
-
0033093678
-
Intraperitoneal gene therapy with adenoviralmediated p53 tumor suppressor gene for ovarian cancer model in nude mouse
-
Kim J, Hwang ES, Kim JS, et al.: Intraperitoneal gene therapy with adenoviralmediated p53 tumor suppressor gene for ovarian cancer model in nude mouse. Cancer Gene Ther. 1999; 6(2): 172-8.
-
(1999)
Cancer Gene Ther
, vol.6
, Issue.2
, pp. 172-178
-
-
Kim, J.1
Hwang, E.S.2
Kim, J.S.3
-
5
-
-
2142639386
-
Adenoviral p53 gene transfer in human bladder cancer cell lines: cytotoxicity and synergy with cisplatin
-
Pagliaro LC, Keyhani A, Liu B, et al.: Adenoviral p53 gene transfer in human bladder cancer cell lines: cytotoxicity and synergy with cisplatin. Urol Oncol. 2003; 21(6): 456-62.
-
(2003)
Urol Oncol
, vol.21
, Issue.6
, pp. 456-462
-
-
Pagliaro, L.C.1
Keyhani, A.2
Liu, B.3
-
6
-
-
0030514283
-
In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer
-
Spitz FR, Nguyen D, Skibber JM, et al.: In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer. Anticancer Res. 1996; 16(6B): 3415-22.
-
(1996)
Anticancer Res
, vol.16
, Issue.6B
, pp. 3415-3422
-
-
Spitz, F.R.1
Nguyen, D.2
Skibber, J.M.3
-
7
-
-
0037072576
-
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
-
Merdan T, Kopecek J, Kissel T: Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev. 2002; 54(5): 715-58.
-
(2002)
Adv Drug Deliv Rev
, vol.54
, Issue.5
, pp. 715-758
-
-
Merdan, T.1
Kopecek, J.2
Kissel, T.3
-
8
-
-
84987630012
-
Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic
-
Moreno PM, Pêgo AP: Therapeutic antisense oligonucleotides against cancer: hurdling to the clinic. Front Chem. 2014; 2: 87.
-
(2014)
Front Chem
, vol.2
, pp. 87
-
-
Moreno, P.M.1
Pêgo, A.P.2
-
9
-
-
20444452034
-
Drug insight: Cancer cell immortalitytelomerase as a target for novel cancer gene therapies
-
Keith WN, Bilsland A, Hardie M, et al.: Drug insight: Cancer cell immortalitytelomerase as a target for novel cancer gene therapies. Nat Clin Pract Oncol. 2004; 1(2): 88-96.
-
(2004)
Nat Clin Pract Oncol
, vol.1
, Issue.2
, pp. 88-96
-
-
Keith, W.N.1
Bilsland, A.2
Hardie, M.3
-
10
-
-
84911118486
-
Gene Therapies for Cancer: Strategies, Challenges and Successes
-
Das SK, Menezes ME, Bhatia S, et al.: Gene Therapies for Cancer: Strategies, Challenges and Successes. J Cell Physiol. 2015; 230(2): 259-71.
-
(2015)
J Cell Physiol
, vol.230
, Issue.2
, pp. 259-271
-
-
Das, S.K.1
Menezes, M.E.2
Bhatia, S.3
-
11
-
-
84908156485
-
Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives
-
Chen GX, Zhang S, He XH, et al.: Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives. Onco Targets Ther. 2014; 7: 1901-9.
-
(2014)
Onco Targets Ther
, vol.7
, pp. 1901-1909
-
-
Chen, G.X.1
Zhang, S.2
He, X.H.3
-
12
-
-
84877856412
-
From mutation identification to therapy: discovery and origins of the first approved gene therapy in the Western world
-
Kastelein JJ, Ross CJ, Hayden MR: From mutation identification to therapy: discovery and origins of the first approved gene therapy in the Western world. Hum Gene Ther. 2013; 24(5): 472-8.
-
(2013)
Hum Gene Ther
, vol.24
, Issue.5
, pp. 472-478
-
-
Kastelein, J.J.1
Ross, C.J.2
Hayden, M.R.3
-
13
-
-
0001511115
-
The Influence of complicating diseases upon leukÆmia
-
Dock G: The Influence of complicating diseases upon leukÆmia. The American Journal of the Medical Sciences. 1904; 127(4): 563-92.
-
(1904)
The American Journal of the Medical Sciences
, vol.127
, Issue.4
, pp. 563-592
-
-
Dock, G.1
-
14
-
-
33947245441
-
History of oncolytic viruses: genesis to genetic engineering
-
Kelly E, Russell SJ: History of oncolytic viruses: genesis to genetic engineering. Mol Ther. 2007; 15(4): 651-9.
-
(2007)
Mol Ther
, vol.15
, Issue.4
, pp. 651-659
-
-
Kelly, E.1
Russell, S.J.2
-
15
-
-
0000343064
-
Present status of oncolytic virus studies
-
Southam CM: Present status of oncolytic virus studies. Trans N Y Acad Sci. 1960; 22(8 Series II): 657-73.
-
(1960)
Trans N Y Acad Sci
, vol.22
, Issue.8
, pp. 657-673
-
-
Southam, C.M.1
-
16
-
-
0027548077
-
Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir
-
Oldfield EH, Ram Z, Culver KW, et al.: Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir. Hum Gene Ther. 1993; 4(1): 39-69.
-
(1993)
Hum Gene Ther
, vol.4
, Issue.1
, pp. 39-69
-
-
Oldfield, E.H.1
Ram, Z.2
Culver, K.W.3
-
17
-
-
84892847173
-
Adenovirus: the first effective in vivo gene delivery vector
-
Crystal RG: Adenovirus: the first effective in vivo gene delivery vector. Hum Gene Ther. 2014; 25(1): 3-11.
-
(2014)
Hum Gene Ther
, vol.25
, Issue.1
, pp. 3-11
-
-
Crystal, R.G.1
-
18
-
-
84893624235
-
Herpes simplex viral vectors: late bloomers with big potential
-
Glorioso JC: Herpes simplex viral vectors: late bloomers with big potential. Hum Gene Ther. 2014; 25(2): 83-91.
-
(2014)
Hum Gene Ther
, vol.25
, Issue.2
, pp. 83-91
-
-
Glorioso, J.C.1
-
19
-
-
84918822684
-
Retroviral vectors: from cancer viruses to therapeutic tools
-
Miller AD: Retroviral vectors: from cancer viruses to therapeutic tools. Hum Gene Ther. 2014; 25(12): 989-94.
-
(2014)
Hum Gene Ther
, vol.25
, Issue.12
, pp. 989-994
-
-
Miller, A.D.1
-
20
-
-
84918827950
-
Development of gene transfer technology
-
Mulligan RC: Development of gene transfer technology. Hum Gene Ther. 2014; 25(12): 995-1002.
-
(2014)
Hum Gene Ther
, vol.25
, Issue.12
, pp. 995-1002
-
-
Mulligan, R.C.1
-
21
-
-
31644442345
-
An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents
-
Rots MG, Elferink MG, Gommans WM, et al.: An ex vivo human model system to evaluate specificity of replicating and non-replicating gene therapy agents. J Gene Med. 2006; 8(1): 35-41.
-
(2006)
J Gene Med
, vol.8
, Issue.1
, pp. 35-41
-
-
Rots, M.G.1
Elferink, M.G.2
Gommans, W.M.3
-
22
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
-
Liu BL, Robinson M, Han Z, et al.: ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Gene Ther. 2003; 10(4): 292-303.
-
(2003)
Gene Ther
, vol.10
, Issue.4
, pp. 292-303
-
-
Liu, B.L.1
Robinson, M.2
Han, Z.3
-
23
-
-
84882418270
-
Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment
-
Hirvinen M, Heiskanen R, Oksanen M, et al.: Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment. J Transl Med. 2013; 11: 193.
-
(2013)
J Transl Med
, vol.11
, pp. 193
-
-
Hirvinen, M.1
Heiskanen, R.2
Oksanen, M.3
-
24
-
-
84878074018
-
Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirus
-
Kanerva A, Nokisalmi P, Diaconu I, et al.: Antiviral and antitumor T-cell immunity in patients treated with GM-CSF-coding oncolytic adenovirus. Clin Cancer Res. 2013; 19(10): 2734-44.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.10
, pp. 2734-2744
-
-
Kanerva, A.1
Nokisalmi, P.2
Diaconu, I.3
-
25
-
-
84859376777
-
Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients
-
Pesonen S, Diaconu I, Kangasniemi L, et al.: Oncolytic immunotherapy of advanced solid tumors with a CD40L-expressing replicating adenovirus: assessment of safety and immunologic responses in patients. Cancer Res. 2012; 72(7): 1621-31.
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1621-1631
-
-
Pesonen, S.1
Diaconu, I.2
Kangasniemi, L.3
-
26
-
-
84957850936
-
Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus
-
Taipale K, Liikanen I, Juhila J, et al.: Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus. Mol Ther. 2016; 24(1): 175-83.
-
(2016)
Mol Ther
, vol.24
, Issue.1
, pp. 175-183
-
-
Taipale, K.1
Liikanen, I.2
Juhila, J.3
-
27
-
-
85031030607
-
Tumor Selectivity of Oncolytic Parvoviruses: From in vitro and Animal Models to Cancer Patients
-
Angelova AL, Geletneky K, Nuesch JP, et al.: Tumor Selectivity of Oncolytic Parvoviruses: From in vitro and Animal Models to Cancer Patients. Front Bioeng Biotechnol. 2015; 3: 55.
-
(2015)
Front Bioeng Biotechnol
, vol.3
, pp. 55
-
-
Angelova, A.L.1
Geletneky, K.2
Nuesch, J.P.3
-
28
-
-
84952061232
-
Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus
-
Kemp V, Hoeben RC, van den Wollenberg DJ: Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus. Viruses. 2016; 8(1): pii: E4.
-
(2016)
Viruses
, vol.8
, Issue.1
-
-
Kemp, V.1
Hoeben, R.C.2
van den Wollenberg, D.J.3
-
29
-
-
84948976921
-
Vaccinia virus, a promising new therapeutic agent for pancreatic cancer
-
Al Yaghchi C, Zhang Z, Alusi G, et al.: Vaccinia virus, a promising new therapeutic agent for pancreatic cancer. Immunotherapy. 2015; 7(12): 1249-58.
-
(2015)
Immunotherapy
, vol.7
, Issue.12
, pp. 1249-1258
-
-
Al Yaghchi, C.1
Zhang, Z.2
Alusi, G.3
-
30
-
-
65749089629
-
Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis
-
Dorer DE, Nettelbeck DM: Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Adv Drug Deliv Rev. 2009; 61(7-8): 554-71.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.7-8
, pp. 554-571
-
-
Dorer, D.E.1
Nettelbeck, D.M.2
-
31
-
-
27944464545
-
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
-
Berk AJ: Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene. 2005; 24(52): 7673-85.
-
(2005)
Oncogene
, vol.24
, Issue.52
, pp. 7673-7685
-
-
Berk, A.J.1
-
32
-
-
0031451158
-
Viral transactivating proteins
-
Flint J, Shenk T: Viral transactivating proteins. Annu Rev Genet. 1997; 31: 177-212.
-
(1997)
Annu Rev Genet
, vol.31
, pp. 177-212
-
-
Flint, J.1
Shenk, T.2
-
33
-
-
0023099280
-
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
-
Barker DD, Berk AJ: Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology. 1987; 156(1): 107-21.
-
(1987)
Virology
, vol.156
, Issue.1
, pp. 107-121
-
-
Barker, D.D.1
Berk, A.J.2
-
34
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff JR, Kirn DH, Williams A, et al.: An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science. 1996; 274(5286): 373-6.
-
(1996)
Science
, vol.274
, Issue.5286
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
35
-
-
22244479672
-
Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy
-
O'Shea CC, Soria C, Bagus B, et al.: Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy. Cancer Cell. 2005; 8(1): 61-74.
-
(2005)
Cancer Cell
, vol.8
, Issue.1
, pp. 61-74
-
-
O'Shea, C.C.1
Soria, C.2
Bagus, B.3
-
36
-
-
20144368516
-
Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas
-
Galanis E, Okuno SH, Nascimento AG, et al.: Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas. Gene Ther. 2005; 12(5): 437-45.
-
(2005)
Gene Ther
, vol.12
, Issue.5
, pp. 437-445
-
-
Galanis, E.1
Okuno, S.H.2
Nascimento, A.G.3
-
37
-
-
85047699490
-
Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma
-
Habib N, Salama H, Abd El Latif Abu Median A, et al.: Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma. Cancer Gene Ther. 2002; 9(3): 254-9.
-
(2002)
Cancer Gene Ther
, vol.9
, Issue.3
, pp. 254-259
-
-
Habib, N.1
Salama, H.2
Abd El Latif Abu Median, A.3
-
38
-
-
0035835373
-
E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors
-
Habib NA, Sarraf CE, Mitry RR, et al.: E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors. Hum Gene Ther. 2001; 12(3): 219-26.
-
(2001)
Hum Gene Ther
, vol.12
, Issue.3
, pp. 219-226
-
-
Habib, N.A.1
Sarraf, C.E.2
Mitry, R.R.3
-
39
-
-
0033831080
-
a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly I, et al.: a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med. 2000; 6(8): 879-85.
-
(2000)
Nat Med
, vol.6
, Issue.8
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
40
-
-
0037314655
-
Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies
-
Makower D, Rozenblit A, Kaufman H, et al.: Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies. Clin Cancer Res. 2003; 9(2): 693-702.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.2
, pp. 693-702
-
-
Makower, D.1
Rozenblit, A.2
Kaufman, H.3
-
41
-
-
0036828125
-
Hepatic arterial infusion of a replicationselective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints
-
Reid T, Galanis E, Abbruzzese J, et al.: Hepatic arterial infusion of a replicationselective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. Cancer Res. 2002; 62(21): 6070-9.
-
(2002)
Cancer Res
, vol.62
, Issue.21
, pp. 6070-6079
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
-
42
-
-
22944476168
-
Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin
-
Reid TR, Freeman S, Post L, et al.: Effects of Onyx-015 among metastatic colorectal cancer patients that have failed prior treatment with 5-FU/leucovorin. Cancer Gene Ther. 2005; 12(8): 673-81.
-
(2005)
Cancer Gene Ther
, vol.12
, Issue.8
, pp. 673-681
-
-
Reid, T.R.1
Freeman, S.2
Post, L.3
-
43
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo J, Gomez-Manzano C, Alemany R, et al.: A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene. 2000; 19(1): 2-12.
-
(2000)
Oncogene
, vol.19
, Issue.1
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
-
44
-
-
0035138689
-
A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency
-
Suzuki K, Fueyo J, Krasnykh V, et al.: A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency. Clin Cancer Res. 2001; 7(1): 120-6.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.1
, pp. 120-126
-
-
Suzuki, K.1
Fueyo, J.2
Krasnykh, V.3
-
45
-
-
0031052263
-
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
-
Bergelson JM, Cunningham JA, Droguett G, et al.: Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science. 1997; 275(5304): 1320-3.
-
(1997)
Science
, vol.275
, Issue.5304
, pp. 1320-1323
-
-
Bergelson, J.M.1
Cunningham, J.A.2
Droguett, G.3
-
46
-
-
0032829560
-
Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR
-
Kirby I, Davison E, Beavil AJ, et al.: Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR. J Virol. 1999; 73(11): 9508-14.
-
(1999)
J Virol
, vol.73
, Issue.11
, pp. 9508-9514
-
-
Kirby, I.1
Davison, E.2
Beavil, A.J.3
-
47
-
-
13044300857
-
Identification of a conserved receptorbinding site on the fiber proteins of CAR-recognizing adenoviridae
-
Roelvink PW, Mi Lee G, Einfeld DA, et al.: Identification of a conserved receptorbinding site on the fiber proteins of CAR-recognizing adenoviridae. Science. 1999; 286(5444): 1568-71.
-
(1999)
Science
, vol.286
, Issue.5444
, pp. 1568-1571
-
-
Roelvink, P.W.1
Mi Lee, G.2
Einfeld, D.A.3
-
48
-
-
0031950120
-
Adenovirus internalization and infection require dynamin
-
Wang K, Huang S, Kapoor-Munshi A, et al.: Adenovirus internalization and infection require dynamin. J Virol. 1998; 72(4): 3455-8.
-
(1998)
J Virol
, vol.72
, Issue.4
, pp. 3455-3458
-
-
Wang, K.1
Huang, S.2
Kapoor-Munshi, A.3
-
49
-
-
0027166647
-
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment
-
Wickham TJ, Mathias P, Cheresh DA, et al.: Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment. Cell. 1993; 73(2): 309-19.
-
(1993)
Cell
, vol.73
, Issue.2
, pp. 309-319
-
-
Wickham, T.J.1
Mathias, P.2
Cheresh, D.A.3
-
50
-
-
0035910098
-
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction
-
Cohen CJ, Shieh JT, Pickles RJ, et al.: The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc Natl Acad Sci U S A. 2001; 98(26): 15191-6.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.26
, pp. 15191-15196
-
-
Cohen, C.J.1
Shieh, J.T.2
Pickles, R.J.3
-
51
-
-
79959377608
-
The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells
-
Hamdan S, Verbeke CS, Fox N, et al.: The roles of cell surface attachment molecules and coagulation Factor X in adenovirus 5-mediated gene transfer in pancreatic cancer cells. Cancer Gene Ther. 2011; 18(7): 478-88.
-
(2011)
Cancer Gene Ther
, vol.18
, Issue.7
, pp. 478-488
-
-
Hamdan, S.1
Verbeke, C.S.2
Fox, N.3
-
52
-
-
67449164596
-
Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses
-
Strauss R, Sova P, Liu Y, et al.: Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses. Cancer Res. 2009; 69(12): 5115-25.
-
(2009)
Cancer Res
, vol.69
, Issue.12
, pp. 5115-5125
-
-
Strauss, R.1
Sova, P.2
Liu, Y.3
-
53
-
-
78651260394
-
Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14
-
Wang H, Li ZY, Liu Y, et al.: Desmoglein 2 is a receptor for adenovirus serotypes 3, 7, 11 and 14. Nat Med. 2011; 17(1): 96-104.
-
(2011)
Nat Med
, vol.17
, Issue.1
, pp. 96-104
-
-
Wang, H.1
Li, Z.Y.2
Liu, Y.3
-
54
-
-
10744222544
-
Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus
-
Kanerva A, Zinn KR, Chaudhuri TR, et al.: Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus. Mol Ther. 2003; 8(3): 449-58.
-
(2003)
Mol Ther
, vol.8
, Issue.3
, pp. 449-458
-
-
Kanerva, A.1
Zinn, K.R.2
Chaudhuri, T.R.3
-
55
-
-
77953160443
-
Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients
-
Cerullo V, Pesonen S, Diaconu I, et al.: Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients. Cancer Res. 2010; 70(11): 4297-309.
-
(2010)
Cancer Res
, vol.70
, Issue.11
, pp. 4297-4309
-
-
Cerullo, V.1
Pesonen, S.2
Diaconu, I.3
-
56
-
-
84924280819
-
Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy
-
Hemminki O, Parviainen S, Juhila J, et al.: Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy. Oncotarget. 2015; 6(6): 4467-81.
-
(2015)
Oncotarget
, vol.6
, Issue.6
, pp. 4467-4481
-
-
Hemminki, O.1
Parviainen, S.2
Juhila, J.3
-
57
-
-
34548137729
-
Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway
-
Cascallo M, Alonso MM, Rojas JJ, et al.: Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway. Mol Ther. 2007; 15(9): 1607-15.
-
(2007)
Mol Ther
, vol.15
, Issue.9
, pp. 1607-1615
-
-
Cascallo, M.1
Alonso, M.M.2
Rojas, J.J.3
-
58
-
-
49149090311
-
Directed evolution generates a novel oncolytic virus for the treatment of colon cancer
-
Kuhn I, Harden P, Bauzon M, et al.: Directed evolution generates a novel oncolytic virus for the treatment of colon cancer. PLoS One. 2008; 3(6): e2409.
-
(2008)
PLoS One
, vol.3
, Issue.6
-
-
Kuhn, I.1
Harden, P.2
Bauzon, M.3
-
59
-
-
0041563779
-
Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors
-
Fishelson Z, Donin N, Zell S, et al.: Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors. Mol Immunol. 2003; 40(2-4): 109-23.
-
(2003)
Mol Immunol
, vol.40
, Issue.2-4
, pp. 109-123
-
-
Fishelson, Z.1
Donin, N.2
Zell, S.3
-
60
-
-
0041387516
-
Adenovirus type 11 uses CD46 as a cellular receptor
-
Segerman A, Atkinson JP, Marttila M, et al.: Adenovirus type 11 uses CD46 as a cellular receptor. J Virol. 2003; 77(17): 9183-91.
-
(2003)
J Virol
, vol.77
, Issue.17
, pp. 9183-9191
-
-
Segerman, A.1
Atkinson, J.P.2
Marttila, M.3
-
61
-
-
0025975357
-
Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence
-
MacLean AR, ul-Fareed M, Robertson L, et al.: Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence. J Gen Virol. 1991; 72(Pt 3): 631-9.
-
(1991)
J Gen Virol
, vol.72
, pp. 631-639
-
-
MacLean, A.R.1
ul-Fareed, M.2
Robertson, L.3
-
62
-
-
0028085566
-
Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2
-
Brown SM, Harland J, MacLean AR, et al.: Cell type and cell state determine differential in vitro growth of non-neurovirulent ICP34.5-negative herpes simplex virus types 1 and 2. J Gen Virol. 1994; 75(Pt 9): 2367-77.
-
(1994)
J Gen Virol
, vol.75
, pp. 2367-2377
-
-
Brown, S.M.1
Harland, J.2
MacLean, A.R.3
-
63
-
-
0028892032
-
Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant
-
Kesari S, Randazzo BP, Valyi-Nagy T, et al.: Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Lab Invest. 1995; 73(5): 636-48.
-
(1995)
Lab Invest
, vol.73
, Issue.5
, pp. 636-648
-
-
Kesari, S.1
Randazzo, B.P.2
Valyi-Nagy, T.3
-
64
-
-
85047699172
-
The potential for efficacy of the modified (ICP 34.5-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study
-
Papanastassiou V, Rampling R, Fraser M, et al.: The potential for efficacy of the modified (ICP 34.5-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study. Gene Ther. 2002; 9(6): 398-406.
-
(2002)
Gene Ther
, vol.9
, Issue.6
, pp. 398-406
-
-
Papanastassiou, V.1
Rampling, R.2
Fraser, M.3
-
65
-
-
12944272092
-
Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma
-
Rampling R, Cruickshank G, Papanastassiou V, et al.: Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma. Gene Ther. 2000; 7(10): 859-66.
-
(2000)
Gene Ther
, vol.7
, Issue.10
, pp. 859-866
-
-
Rampling, R.1
Cruickshank, G.2
Papanastassiou, V.3
-
66
-
-
8844274068
-
HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival
-
Harrow S, Papanastassiou V, Harland J, et al.: HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival. Gene Ther. 2004; 11(22): 1648-58.
-
(2004)
Gene Ther
, vol.11
, Issue.22
, pp. 1648-1658
-
-
Harrow, S.1
Papanastassiou, V.2
Harland, J.3
-
67
-
-
0029023868
-
Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas
-
Mineta T, Rabkin SD, Yazaki T, et al.: Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat Med. 1995; 1(9): 938-43.
-
(1995)
Nat Med
, vol.1
, Issue.9
, pp. 938-943
-
-
Mineta, T.1
Rabkin, S.D.2
Yazaki, T.3
-
68
-
-
12944315014
-
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial
-
Markert JM, Medlock MD, Rabkin SD, et al.: Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial. Gene Ther. 2000; 7(10): 867-74.
-
(2000)
Gene Ther
, vol.7
, Issue.10
, pp. 867-874
-
-
Markert, J.M.1
Medlock, M.D.2
Rabkin, S.D.3
-
69
-
-
58149237728
-
Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM
-
Markert JM, Liechty PG, Wang W, et al.: Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM. Mol Ther. 2009; 17(1): 199-207.
-
(2009)
Mol Ther
, vol.17
, Issue.1
, pp. 199-207
-
-
Markert, J.M.1
Liechty, P.G.2
Wang, W.3
-
70
-
-
84899975310
-
A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses
-
Markert JM, Razdan SN, Kuo HC, et al.: A phase 1 trial of oncolytic HSV-1, G207, given in combination with radiation for recurrent GBM demonstrates safety and radiographic responses. Mol Ther. 2014; 22(5): 1048-55.
-
(2014)
Mol Ther
, vol.22
, Issue.5
, pp. 1048-1055
-
-
Markert, J.M.1
Razdan, S.N.2
Kuo, H.C.3
-
71
-
-
0032472875
-
Infected cell protein (ICP)47 enhances herpes simplex virus neurovirulence by blocking the CD8+ T cell response
-
Goldsmith K, Chen W, Johnson DC, et al.: Infected cell protein (ICP)47 enhances herpes simplex virus neurovirulence by blocking the CD8+ T cell response. J Exp Med. 1998; 187(3): 341-8.
-
(1998)
J Exp Med
, vol.187
, Issue.3
, pp. 341-348
-
-
Goldsmith, K.1
Chen, W.2
Johnson, D.C.3
-
72
-
-
84933586864
-
Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
-
Andtbacka RH, Kaufman HL, Collichio F, et al.: Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma. J Clin Oncol. 2015; 33(25): 2780-8.
-
(2015)
J Clin Oncol
, vol.33
, Issue.25
, pp. 2780-2788
-
-
Andtbacka, R.H.1
Kaufman, H.L.2
Collichio, F.3
-
73
-
-
84947704341
-
Long-term efficacy of pembrolizumab (pembro; MK-3475) in a pooled analysis of 655 patients with advanced melanoma (MEL) enrolled in KEYNOTE-001
-
Duad A, Ribas A, Robert C, et al.: Long-term efficacy of pembrolizumab (pembro; MK-3475) in a pooled analysis of 655 patients with advanced melanoma (MEL) enrolled in KEYNOTE-001. J Clin Oncol. 2015; 33(suppl): Abstract 9005.
-
(2015)
J Clin Oncol
, vol.33
-
-
Duad, A.1
Ribas, A.2
Robert, C.3
-
74
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al.: Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010; 363(8): 711-23.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
75
-
-
84977111376
-
Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma
-
Kaufman HL, Ruby CE, Hughes T, et al.: Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma. J Immunother Cancer. 2014; 2: 11.
-
(2014)
J Immunother Cancer
, vol.2
, pp. 11
-
-
Kaufman, H.L.1
Ruby, C.E.2
Hughes, T.3
-
76
-
-
84952985128
-
Talimogene Laherparepvec: First Global Approval
-
Greig SL: Talimogene Laherparepvec: First Global Approval. Drugs. 2016; 76(1): 147-54.
-
(2016)
Drugs
, vol.76
, Issue.1
, pp. 147-154
-
-
Greig, S.L.1
-
77
-
-
84979599378
-
Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma
-
Puzanov I, Milhem MM, Minor D, et al.: Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma. J Clin Oncol. 2016; 34(22): 2619-26.
-
(2016)
J Clin Oncol
, vol.34
, Issue.22
, pp. 2619-2626
-
-
Puzanov, I.1
Milhem, M.M.2
Minor, D.3
-
78
-
-
84926160709
-
Immune evasion in cancer: Mechanistic basis and therapeutic strategies
-
Vinay DS, Ryan EP, Pawelec G, et al.: Immune evasion in cancer: Mechanistic basis and therapeutic strategies. Semin Cancer Biol. 2015; 35(Suppl): S185-98.
-
(2015)
Semin Cancer Biol
, vol.35
, pp. S185-S198
-
-
Vinay, D.S.1
Ryan, E.P.2
Pawelec, G.3
-
79
-
-
0029955865
-
Human melanoma antigens recognized by T lymphocytes
-
Kawakami Y, Robbins PF, Rosenberg SA: Human melanoma antigens recognized by T lymphocytes. Keio J Med. 1996; 45(2): 100-8.
-
(1996)
Keio J Med
, vol.45
, Issue.2
, pp. 100-108
-
-
Kawakami, Y.1
Robbins, P.F.2
Rosenberg, S.A.3
-
80
-
-
84958213866
-
Exploiting the Immunogenic Potential of Cancer Cells for Improved Dendritic Cell Vaccines
-
Vandenberk L, Belmans J, Van Woensel M, et al.: Exploiting the Immunogenic Potential of Cancer Cells for Improved Dendritic Cell Vaccines. Front Immunol. 2015; 6: 663.
-
(2015)
Front Immunol
, vol.6
, pp. 663
-
-
Vandenberk, L.1
Belmans, J.2
Van Woensel, M.3
-
81
-
-
84903527674
-
Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial
-
Middleton G, Silcocks P, Cox T, et al.: Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial. Lancet Oncol. 2014; 15(8): 829-40.
-
(2014)
Lancet Oncol
, vol.15
, Issue.8
, pp. 829-840
-
-
Middleton, G.1
Silcocks, P.2
Cox, T.3
-
82
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry RV, Chemnitz JM, Frauwirth KA, et al.: CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms. Mol Cell Biol. 2005; 25(21): 9543-53.
-
(2005)
Mol Cell Biol
, vol.25
, Issue.21
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
-
83
-
-
84899631361
-
Antibody-modified T cells: CARs take the front seat for hematologic malignancies
-
Maus MV, Grupp SA, Porter DL, et al.: Antibody-modified T cells: CARs take the front seat for hematologic malignancies. Blood. 2014; 123(17): 2625-35.
-
(2014)
Blood
, vol.123
, Issue.17
, pp. 2625-2635
-
-
Maus, M.V.1
Grupp, S.A.2
Porter, D.L.3
-
84
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
Brentjens RJ, Rivière I, Park JH, et al.: Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood. 2011; 118(18): 4817-28.
-
(2011)
Blood
, vol.118
, Issue.18
, pp. 4817-4828
-
-
Brentjens, R.J.1
Rivière, I.2
Park, J.H.3
-
85
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL, et al.: T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med. 2011; 3(95): 95ra73.
-
(2011)
Sci Transl Med
, vol.3
, Issue.95
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
-
86
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA, et al.: B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood. 2012; 119(12): 2709-20.
-
(2012)
Blood
, vol.119
, Issue.12
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
87
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter DL, Levine BL, Kalos M, et al.: Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med. 2011; 365(8): 725-33.
-
(2011)
N Engl J Med
, vol.365
, Issue.8
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
-
88
-
-
84937790930
-
A drive through cellular therapy for CLL in 2015: allogeneic cell transplantation and CARs
-
Mato A, Porter DL: A drive through cellular therapy for CLL in 2015: allogeneic cell transplantation and CARs. Blood. 2015; 126(4): 478-85.
-
(2015)
Blood
, vol.126
, Issue.4
, pp. 478-485
-
-
Mato, A.1
Porter, D.L.2
-
89
-
-
84897484486
-
CAR T cells for solid tumors: armed and ready to go?
-
Kakarla S, Gottschalk S: CAR T cells for solid tumors: armed and ready to go? Cancer J. 2014; 20(2): 151-5.
-
(2014)
Cancer J
, vol.20
, Issue.2
, pp. 151-155
-
-
Kakarla, S.1
Gottschalk, S.2
-
90
-
-
84943579933
-
T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice
-
VanSeggelen H, Hammill JA, Dvorkin-Gheva A, et al.: T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice. Mol Ther. 2015; 23(10): 1600-10.
-
(2015)
Mol Ther
, vol.23
, Issue.10
, pp. 1600-1610
-
-
VanSeggelen, H.1
Hammill, J.A.2
Dvorkin-Gheva, A.3
-
91
-
-
0034292410
-
Expression of a human coxsackie/adenovirus receptor transgene permits adenovirus infection of primary lymphocytes
-
Schmidt MR, Piekos B, Cabatingan MS, et al.: Expression of a human coxsackie/adenovirus receptor transgene permits adenovirus infection of primary lymphocytes. J Immunol. 2000; 165(7): 4112-9.
-
(2000)
J Immunol
, vol.165
, Issue.7
, pp. 4112-4119
-
-
Schmidt, M.R.1
Piekos, B.2
Cabatingan, M.S.3
-
92
-
-
84907546628
-
Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors
-
Nishio N, Diaconu I, Liu H, et al.: Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors. Cancer Res. 2014; 74(18): 5195-205.
-
(2014)
Cancer Res
, vol.74
, Issue.18
, pp. 5195-5205
-
-
Nishio, N.1
Diaconu, I.2
Liu, H.3
-
93
-
-
84883450737
-
Regulatory evaluation of Glybera in Europe-two committees, one mission
-
Melchiorri D, Pani L, Gasparini P, et al.: Regulatory evaluation of Glybera in Europe-two committees, one mission. Nat Rev Drug Discov. 2013; 12(9): 719.
-
(2013)
Nat Rev Drug Discov
, vol.12
, Issue.9
, pp. 719
-
-
Melchiorri, D.1
Pani, L.2
Gasparini, P.3
-
94
-
-
84904411409
-
Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European Union
-
Narayanan G, Cossu G, Galli MC, et al.: Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European Union. Hum Gene Ther Clin Dev. 2014; 25(1): 1-6.
-
(2014)
Hum Gene Ther Clin Dev
, vol.25
, Issue.1
, pp. 1-6
-
-
Narayanan, G.1
Cossu, G.2
Galli, M.C.3
-
95
-
-
85015249064
-
Re-examination of regulatory opinions in Europe: possible contribution for the approval of the first gene therapy product Glybera
-
Watanabe N, Yano K, Tsuyuki K, et al.: Re-examination of regulatory opinions in Europe: possible contribution for the approval of the first gene therapy product Glybera. Mol Ther Methods Clin Dev. 2015; 2: 14066.
-
(2015)
Mol Ther Methods Clin Dev
, vol.2
, pp. 14066
-
-
Watanabe, N.1
Yano, K.2
Tsuyuki, K.3
-
96
-
-
84866899464
-
Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union
-
Ylä-Herttuala S: Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union. Mol Ther. 2012; 20(10): 1831-2.
-
(2012)
Mol Ther
, vol.20
, Issue.10
, pp. 1831-1832
-
-
Ylä-Herttuala, S.1
-
99
-
-
84924937245
-
Perspectives on best practices for gene therapy programs
-
Cheever TR, Berkley D, Braun S, et al.: Perspectives on best practices for gene therapy programs. Hum Gene Ther. 2015; 26(3): 127-33.
-
(2015)
Hum Gene Ther
, vol.26
, Issue.3
, pp. 127-133
-
-
Cheever, T.R.1
Berkley, D.2
Braun, S.3
-
100
-
-
17844375955
-
Intra-peritoneal administration of genetic therapies: promises and pitfalls
-
Evans TR, Keith WN: Intra-peritoneal administration of genetic therapies: promises and pitfalls. Minerva Ginecol. 2004; 56(6): 529-38.
-
(2004)
Minerva Ginecol
, vol.56
, Issue.6
, pp. 529-538
-
-
Evans, T.R.1
Keith, W.N.2
-
101
-
-
85010888198
-
Manufacturing of viral vectors for gene therapy: Part I. Upstream processing
-
Merten OW, Schweizer M, Chahal P, et al.: Manufacturing of viral vectors for gene therapy: Part I. Upstream processing. Pharm Bioprocess. 2014; 2(2): 183-203.
-
(2014)
Pharm Bioprocess
, vol.2
, Issue.2
, pp. 183-203
-
-
Merten, O.W.1
Schweizer, M.2
Chahal, P.3
-
102
-
-
84883173865
-
Clinical approval success rates for investigational cancer drugs
-
DiMasi JA, Reichert JM, Feldman L, et al.: Clinical approval success rates for investigational cancer drugs. Clin Pharmacol Ther. 2013; 94(3): 329-35.
-
(2013)
Clin Pharmacol Ther
, vol.94
, Issue.3
, pp. 329-335
-
-
DiMasi, J.A.1
Reichert, J.M.2
Feldman, L.3
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