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Volumn 74, Issue 18, 2014, Pages 5195-5205

Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOLYTIC VIRUS;

EID: 84907546628     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0697     Document Type: Article
Times cited : (261)

References (44)
  • 1
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 2011;365:725-33.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 2
    • 84876005284 scopus 로고    scopus 로고
    • CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
    • Brentjens RJ, Davila ML, Riviere I, Park J, Wang X, Cowell LG, et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013;5:177ra38.
    • (2013) Sci Transl Med , vol.5 , pp. 177ra38
    • Brentjens, R.J.1    Davila, M.L.2    Riviere, I.3    Park, J.4    Wang, X.5    Cowell, L.G.6
  • 3
    • 84887821770 scopus 로고    scopus 로고
    • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: A phase 1 study
    • Cruz CR, Micklethwaite KP, Savoldo B, Ramos CA, Lam S, Ku S, et al. Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood 2013;122:2965-73.
    • (2013) Blood , vol.122 , pp. 2965-2973
    • Cruz, C.R.1    Micklethwaite, K.P.2    Savoldo, B.3    Ramos, C.A.4    Lam, S.5    Ku, S.6
  • 4
    • 84878605813 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: Clinical evaluation and management of on-target toxicity
    • Lamers CH, Sleijfer S, van Steenbergen S, van Elzakker P, van Krimpen B, Groot C, et al. Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity. Mol Ther 2013;21:904-12.
    • (2013) Mol Ther , vol.21 , pp. 904-912
    • Lamers, C.H.1    Sleijfer, S.2    Van Steenbergen, S.3    Van Elzakker, P.4    Van Krimpen, B.5    Groot, C.6
  • 5
    • 33947265424 scopus 로고    scopus 로고
    • Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
    • Park JR, Digiusto DL, Slovak M, Wright C, Naranjo A, Wagner J, et al. Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma. Mol Ther 2007;15:825-33.
    • (2007) Mol Ther , vol.15 , pp. 825-833
    • Park, J.R.1    Digiusto, D.L.2    Slovak, M.3    Wright, C.4    Naranjo, A.5    Wagner, J.6
  • 6
    • 55549145071 scopus 로고    scopus 로고
    • Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
    • Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med 2008;14:1264-70.
    • (2008) Nat Med , vol.14 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3    Rossig, C.4    Russell, H.V.5    Dotti, G.6
  • 8
    • 79960393113 scopus 로고    scopus 로고
    • Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T (reg) cells
    • Facciabene A, Peng X, Hagemann IS, Balint K, Barchetti A, Wang LP, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T (reg) cells. Nature 2011;475:226-30.
    • (2011) Nature , vol.475 , pp. 226-230
    • Facciabene, A.1    Peng, X.2    Hagemann, I.S.3    Balint, K.4    Barchetti, A.5    Wang, L.P.6
  • 9
    • 34447256838 scopus 로고    scopus 로고
    • Regulatory T lymphocytes: Pivotal components of the host antitumor response
    • Yakirevich E, Resnick MB. Regulatory T lymphocytes: pivotal components of the host antitumor response. J Clin Oncol 2007;25:2506-8.
    • (2007) J Clin Oncol , vol.25 , pp. 2506-2508
    • Yakirevich, E.1    Resnick, M.B.2
  • 10
    • 1842562212 scopus 로고    scopus 로고
    • Tolerance and cancer: Mechanisms of tumor evasion and strategies for breaking tolerance
    • Mapara MY, Sykes M. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J Clin Oncol 2004;22:1136-51.
    • (2004) J Clin Oncol , vol.22 , pp. 1136-1151
    • Mapara, M.Y.1    Sykes, M.2
  • 11
    • 0035689762 scopus 로고    scopus 로고
    • Malignant cells, directors of the malignant process: Role of transforming growth factor-beta
    • Teicher BA. Malignant cells, directors of the malignant process: role of transforming growth factor-beta. Cancer Metastasis Rev 2001;20:133-43.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 133-143
    • Teicher, B.A.1
  • 12
    • 0034574306 scopus 로고    scopus 로고
    • The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
    • Siegel RM, Chan FK, Chun HJ, Lenardo MJ. The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity. Nat Immunol 2000;1:469-74.
    • (2000) Nat Immunol , vol.1 , pp. 469-474
    • Siegel, R.M.1    Chan, F.K.2    Chun, H.J.3    Lenardo, M.J.4
  • 13
    • 70349562580 scopus 로고    scopus 로고
    • Programmed death 1 signaling on chronic myeloid leukemia-specificT cells results in T-cell exhaustion and disease progression
    • Mumprecht S, Schurch C, Schwaller J, Solenthaler M, Ochsenbein AF. Programmed death 1 signaling on chronic myeloid leukemia-specificT cells results in T-cell exhaustion and disease progression. Blood 2009;114:1528-36.
    • (2009) Blood , vol.114 , pp. 1528-1536
    • Mumprecht, S.1    Schurch, C.2    Schwaller, J.3    Solenthaler, M.4    Ochsenbein, A.F.5
  • 14
    • 0036137615 scopus 로고    scopus 로고
    • Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta/CD28 receptor
    • Maher J, Brentjens RJ, Gunset G, Riviere I, Sadelain M. Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRzeta/CD28 receptor. Nat Biotechnol 2002;20:70-5.
    • (2002) Nat Biotechnol , vol.20 , pp. 70-75
    • Maher, J.1    Brentjens, R.J.2    Gunset, G.3    Riviere, I.4    Sadelain, M.5
  • 15
    • 33845256434 scopus 로고    scopus 로고
    • T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells
    • Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C, et al. T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 2006;108:3890-7.
    • (2006) Blood , vol.108 , pp. 3890-3897
    • Vera, J.1    Savoldo, B.2    Vigouroux, S.3    Biagi, E.4    Pule, M.5    Rossig, C.6
  • 16
    • 27744566329 scopus 로고    scopus 로고
    • A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
    • Pule MA, Straathof KC, Dotti G, Heslop HE, Rooney CM, Brenner MK. A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol Ther 2005;12:933-41.
    • (2005) Mol Ther , vol.12 , pp. 933-941
    • Pule, M.A.1    Straathof, K.C.2    Dotti, G.3    Heslop, H.E.4    Rooney, C.M.5    Brenner, M.K.6
  • 17
    • 3042551216 scopus 로고    scopus 로고
    • Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
    • Imai C, Mihara K, Andreansky M, Nicholson IC, Pui CH, Geiger TL, et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 2004;18:676-84.
    • (2004) Leukemia , vol.18 , pp. 676-684
    • Imai, C.1    Mihara, K.2    Andreansky, M.3    Nicholson, I.C.4    Pui, C.H.5    Geiger, T.L.6
  • 19
    • 84871939748 scopus 로고    scopus 로고
    • Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: Implications for adoptive T cell-based therapies for lymphoma
    • Perna SK, De Angelis B, Pagliara D, Hasan ST, Zhang L, Mahendravada A, et al. Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma. Clin Cancer Res 2013;19:106-17.
    • (2013) Clin Cancer Res , vol.19 , pp. 106-117
    • Perna, S.K.1    De Angelis, B.2    Pagliara, D.3    Hasan, S.T.4    Zhang, L.5    Mahendravada, A.6
  • 20
    • 0036428790 scopus 로고    scopus 로고
    • Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
    • Kershaw MH, Wang G, Westwood JA, Pachynski RK, Tiffany HL, Marincola FM, et al. Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther 2002;13:1971-80.
    • (2002) Hum Gene Ther , vol.13 , pp. 1971-1980
    • Kershaw, M.H.1    Wang, G.2    Westwood, J.A.3    Pachynski, R.K.4    Tiffany, H.L.5    Marincola, F.M.6
  • 21
    • 67650638846 scopus 로고    scopus 로고
    • T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model
    • Di Stasi A, De Angelis B, Rooney CM, Zhang L, Mahendravada A, Foster AE, et al. T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood 2009;113:6392-402.
    • (2009) Blood , vol.113 , pp. 6392-6402
    • Di Stasi, A.1    De Angelis, B.2    Rooney, C.M.3    Zhang, L.4    Mahendravada, A.5    Foster, A.E.6
  • 22
    • 77958063691 scopus 로고    scopus 로고
    • Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
    • Craddock JA, Lu A, Bear A, Pule M, Brenner MK, Rooney CM, et al. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother 2010;33:780-8.
    • (2010) J Immunother , vol.33 , pp. 780-788
    • Craddock, J.A.1    Lu, A.2    Bear, A.3    Pule, M.4    Brenner, M.K.5    Rooney, C.M.6
  • 23
    • 0036566184 scopus 로고    scopus 로고
    • Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
    • Bollard CM, Rossig C, Calonge MJ, Huls MH, Wagner HJ, Massague J, et al. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood 2002;99:3179-87.
    • (2002) Blood , vol.99 , pp. 3179-3187
    • Bollard, C.M.1    Rossig, C.2    Calonge, M.J.3    Huls, M.H.4    Wagner, H.J.5    Massague, J.6
  • 24
    • 20444425695 scopus 로고    scopus 로고
    • Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis
    • Dotti G, Savoldo B, Pule M, Straathof KC, Biagi E, Yvon E, et al. Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. Blood 2005;105:4677-84.
    • (2005) Blood , vol.105 , pp. 4677-4684
    • Dotti, G.1    Savoldo, B.2    Pule, M.3    Straathof, K.C.4    Biagi, E.5    Yvon, E.6
  • 25
    • 77954590000 scopus 로고    scopus 로고
    • Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
    • Hoyos V, Savoldo B, Quintarelli C, Mahendravada A, Zhang M, Vera J, et al. Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety. Leukemia 2010;24:1160-70.
    • (2010) Leukemia , vol.24 , pp. 1160-1170
    • Hoyos, V.1    Savoldo, B.2    Quintarelli, C.3    Mahendravada, A.4    Zhang, M.5    Vera, J.6
  • 26
    • 84858759305 scopus 로고    scopus 로고
    • Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
    • Pegram HJ, Lee JC, Hayman EG, Imperato GH, Tedder TF, Sadelain M, et al. Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 2012;119:4133-41.
    • (2012) Blood , vol.119 , pp. 4133-4141
    • Pegram, H.J.1    Lee, J.C.2    Hayman, E.G.3    Imperato, G.H.4    Tedder, T.F.5    Sadelain, M.6
  • 27
    • 67349252824 scopus 로고    scopus 로고
    • Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7
    • Vera JF, Hoyos V, Savoldo B, Quintarelli C, Giordano Attianese GM, Leen AM, et al. Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7. Mol Ther 2009;17:880-8.
    • (2009) Mol Ther , vol.17 , pp. 880-888
    • Vera, J.F.1    Hoyos, V.2    Savoldo, B.3    Quintarelli, C.4    Giordano Attianese, G.M.5    Leen, A.M.6
  • 29
    • 28844444483 scopus 로고    scopus 로고
    • Recent progress in the battle between oncolytic viruses and tumours
    • Parato KA, Senger D, Forsyth PA, Bell JC. Recent progress in the battle between oncolytic viruses and tumours. Nat Rev Cancer 2005;5:965-76.
    • (2005) Nat Rev Cancer , vol.5 , pp. 965-976
    • Parato, K.A.1    Senger, D.2    Forsyth, P.A.3    Bell, J.C.4
  • 30
    • 84875225339 scopus 로고    scopus 로고
    • Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
    • Heo J, Reid T, Ruo L, Breitbach CJ, Rose S, Bloomston M, et al. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med 2013;19:329-36.
    • (2013) Nat Med , vol.19 , pp. 329-336
    • Heo, J.1    Reid, T.2    Ruo, L.3    Breitbach, C.J.4    Rose, S.5    Bloomston, M.6
  • 31
    • 10744222544 scopus 로고    scopus 로고
    • Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus
    • Kanerva A, Zinn KR, Chaudhuri TR, Lam JT, Suzuki K, Uil TG, et al. Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus. Mol Ther 2003;8:449-58.
    • (2003) Mol Ther , vol.8 , pp. 449-458
    • Kanerva, A.1    Zinn, K.R.2    Chaudhuri, T.R.3    Lam, J.T.4    Suzuki, K.5    Uil, T.G.6
  • 32
    • 79952198769 scopus 로고    scopus 로고
    • Fluorochromelabeled inhibitors of caspases: Convenient in vitro and in vivo markers of apoptotic cells for cytometric analysis
    • Darzynkiewicz Z, Pozarowski P, Lee BW, Johnson GL. Fluorochromelabeled inhibitors of caspases: convenient in vitro and in vivo markers of apoptotic cells for cytometric analysis. Methods Mol Biol 2011;682:103-14.
    • (2011) Methods Mol Biol , vol.682 , pp. 103-114
    • Darzynkiewicz, Z.1    Pozarowski, P.2    Lee, B.W.3    Johnson, G.L.4
  • 33
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 2011;121:1822-6.
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3    Mims, M.P.4    Keating, M.J.5    Carrum, G.6
  • 34
    • 84860520650 scopus 로고    scopus 로고
    • Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus
    • Diaconu I, Cerullo V, Hirvinen ML, Escutenaire S, Ugolini M, Pesonen SK, et al. Immune response is an important aspect of the antitumor effect produced by a CD40L-encoding oncolytic adenovirus. Cancer Res 2012;72:2327-38.
    • (2012) Cancer Res , vol.72 , pp. 2327-2338
    • Diaconu, I.1    Cerullo, V.2    Hirvinen, M.L.3    Escutenaire, S.4    Ugolini, M.5    Pesonen, S.K.6
  • 36
    • 79953327283 scopus 로고    scopus 로고
    • Chemokine expression from oncolytic vaccinia virus enhances vaccine therapies of cancer
    • Li J, O'Malley M, Urban J, Sampath P, Guo ZS, Kalinski P, et al. Chemokine expression from oncolytic vaccinia virus enhances vaccine therapies of cancer. Mol Ther 2011;19:650-7.
    • (2011) Mol Ther , vol.19 , pp. 650-657
    • Li, J.1    O'Malley, M.2    Urban, J.3    Sampath, P.4    Guo, Z.S.5    Kalinski, P.6
  • 38
    • 63149148047 scopus 로고    scopus 로고
    • Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer
    • Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, et al. Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer. J Immunol 2009;182:1746-55.
    • (2009) J Immunol , vol.182 , pp. 1746-1755
    • Tan, M.C.1    Goedegebuure, P.S.2    Belt, B.A.3    Flaherty, B.4    Sankpal, N.5    Gillanders, W.E.6
  • 40
    • 77952564306 scopus 로고    scopus 로고
    • Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir
    • Diaconu I, Cerullo V, Escutenaire S, Kanerva A, Bauerschmitz GJ, Hernandez-Alcoceba R, et al. Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir. J Gene Med 2010;12:435-45.
    • (2010) J Gene Med , vol.12 , pp. 435-445
    • Diaconu, I.1    Cerullo, V.2    Escutenaire, S.3    Kanerva, A.4    Bauerschmitz, G.J.5    Hernandez-Alcoceba, R.6
  • 41
    • 80054718262 scopus 로고    scopus 로고
    • Oncolytic adenoviruses armed with thymidine kinase can be traced by PET imaging and show potent antitumoural effects by ganciclovir dosing
    • Abate-Daga D, Andreu N, Camacho-Sanchez J, Alemany R, Herance R, Millan O, et al. Oncolytic adenoviruses armed with thymidine kinase can be traced by PET imaging and show potent antitumoural effects by ganciclovir dosing. PLoS One 2011;6:e26142.
    • (2011) PLoS One , vol.6 , pp. e26142
    • Abate-Daga, D.1    Andreu, N.2    Camacho-Sanchez, J.3    Alemany, R.4    Herance, R.5    Millan, O.6
  • 42
    • 42049104455 scopus 로고    scopus 로고
    • Virusmediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation
    • Endo Y, Sakai R, Ouchi M, Onimatsu H, Hioki M, Kagawa S, et al. Virusmediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation. Oncogene 2008;27:2375-81.
    • (2008) Oncogene , vol.27 , pp. 2375-2381
    • Endo, Y.1    Sakai, R.2    Ouchi, M.3    Onimatsu, H.4    Hioki, M.5    Kagawa, S.6
  • 43
    • 84858702868 scopus 로고    scopus 로고
    • Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity
    • Stephenson K.B., Barra NG, Davies E, Ashkar AA, Lichty BD. Expressing human interleukin-15 from oncolytic vesicular stomatitis virus improves survival in a murine metastatic colon adenocarcinoma model through the enhancement of anti-tumor immunity. Cancer Gene Ther 2012;19:238-46.
    • (2012) Cancer Gene Ther , vol.19 , pp. 238-246
    • Stephenson, K.B.1    Barra, N.G.2    Davies, E.3    Ashkar, A.A.4    Lichty, B.D.5
  • 44
    • 80052406557 scopus 로고    scopus 로고
    • Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
    • Breitbach CJ, Burke J, Jonker D, Stephenson J, Haas AR, Chow LQ, et al. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature 2011;477:99-102.
    • (2011) Nature , vol.477 , pp. 99-102
    • Breitbach, C.J.1    Burke, J.2    Jonker, D.3    Stephenson, J.4    Haas, A.R.5    Chow, L.Q.6


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