-
1
-
-
84855792427
-
Cancer statistics, 2012
-
22237781
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012, 62:10-29. 10.3322/caac.20138, 22237781.
-
(2012)
CA Cancer J Clin
, vol.62
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
84872744680
-
-
Fort Washington, PA, National Comprehensive Cancer Network
-
National Comprehensive Cancer Network NCCN Guidelines® Version 2.2013 Melanoma 2012, Fort Washington, PA, National Comprehensive Cancer Network.
-
(2012)
NCCN Guidelines® Version 2.2013 Melanoma
-
-
-
3
-
-
84855585978
-
The immune response to tumors as a tool toward immunotherapy
-
3235449, 22190975
-
Pandolfi F, Cianci R, Pagliari D, Casciano F, Bagala C, Astone A, Landolfi R, Barone C. The immune response to tumors as a tool toward immunotherapy. Clin Dev Immunol 2011, 2011:894704. 3235449, 22190975.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 894704
-
-
Pandolfi, F.1
Cianci, R.2
Pagliari, D.3
Casciano, F.4
Bagala, C.5
Astone, A.6
Landolfi, R.7
Barone, C.8
-
4
-
-
46749103710
-
Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
-
18620949
-
Eggermont AM, Suciu S, Santinami M, Testori A, Kruit WH, Marsden J, Punt CJ, Sales F, Gore M, Mackie R, Kusic Z, Dummer R, Hauschild A, Musat E, Spatz A, Keilholz U, Group EM. Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet 2008, 372:117-126. 10.1016/S0140-6736(08)61033-8, 18620949.
-
(2008)
Lancet
, vol.372
, pp. 117-126
-
-
Eggermont, A.M.1
Suciu, S.2
Santinami, M.3
Testori, A.4
Kruit, W.H.5
Marsden, J.6
Punt, C.J.7
Sales, F.8
Gore, M.9
Mackie, R.10
Kusic, Z.11
Dummer, R.12
Hauschild, A.13
Musat, E.14
Spatz, A.15
Keilholz, U.16
Group, E.M.17
-
5
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
3549297, 20525992
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbe C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010, 363:711-723. 10.1056/NEJMoa1003466, 3549297, 20525992.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
van den Eertwegh, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbe, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
6
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
21639810
-
Robert C, Thomas L, Bondarenko I, O'Day S, DJ M, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011, 364:2517-2526. 10.1056/NEJMoa1104621, 21639810.
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
DJ, M.5
Garbe, C.6
Lebbe, C.7
Baurain, J.F.8
Testori, A.9
Grob, J.J.10
Davidson, N.11
Richards, J.12
Maio, M.13
Hauschild, A.14
Miller, W.H.15
Gascon, P.16
Lotem, M.17
Harmankaya, K.18
Ibrahim, R.19
Francis, S.20
Chen, T.T.21
Humphrey, R.22
Hoos, A.23
Wolchok, J.D.24
more..
-
7
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M, Paradise C, Kunkel L, Rosenberg SA. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol 1999, 17:2105-2116.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
Abrams, J.7
Sznol, M.8
Parkinson, D.9
Hawkins, M.10
Paradise, C.11
Kunkel, L.12
Rosenberg, S.A.13
-
8
-
-
79960299888
-
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
-
3131487, 21498393
-
Rosenberg SA, Yang JC, Sherry RM, Kammula US, Hughes MS, Phan GQ, Citrin DE, Restifo NP, Robbins PF, Wunderlich JR, Morton KE, Laurencot CM, Steinberg SM, White DE, Dudley ME. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011, 17:4550-4557. 10.1158/1078-0432.CCR-11-0116, 3131487, 21498393.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4550-4557
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
Kammula, U.S.4
Hughes, M.S.5
Phan, G.Q.6
Citrin, D.E.7
Restifo, N.P.8
Robbins, P.F.9
Wunderlich, J.R.10
Morton, K.E.11
Laurencot, C.M.12
Steinberg, S.M.13
White, D.E.14
Dudley, M.E.15
-
9
-
-
38349157811
-
Hematopoietic cytokines
-
2200848, 18182579
-
Metcalf D. Hematopoietic cytokines. Blood 2008, 111:485-491. 10.1182/blood-2007-03-079681, 2200848, 18182579.
-
(2008)
Blood
, vol.111
, pp. 485-491
-
-
Metcalf, D.1
-
10
-
-
70349336496
-
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease
-
2727416, 19436055
-
Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease. Blood 2009, 114:1289-1298. 10.1182/blood-2008-12-164004, 2727416, 19436055.
-
(2009)
Blood
, vol.114
, pp. 1289-1298
-
-
Hercus, T.R.1
Thomas, D.2
Guthridge, M.A.3
Ekert, P.G.4
King-Scott, J.5
Parker, M.W.6
Lopez, A.F.7
-
11
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
46336, 8097319
-
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993, 90:3539-3543. 10.1073/pnas.90.8.3539, 46336, 8097319.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
Jackson, V.7
Hamada, H.8
Pardoll, D.9
Mulligan, R.C.10
-
12
-
-
84873592368
-
Mobilization of hematopoietic progenitors from normal donors using the combination of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor results in fewer plasmacytoid dendritic cells in the graft and enhanced donor T cell engraftment with Th1 polarization: results from a randomized clinical trial
-
23201472
-
Lonial S, Akhtari M, Kaufman J, Torre C, Lechowicz MJ, Flowers C, Sinha R, Khoury HJ, Langston AA, Waller EK. Mobilization of hematopoietic progenitors from normal donors using the combination of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor results in fewer plasmacytoid dendritic cells in the graft and enhanced donor T cell engraftment with Th1 polarization: results from a randomized clinical trial. Biol Blood Marrow Transplant 2013, 19:460-467. 10.1016/j.bbmt.2012.11.017, 23201472.
-
(2013)
Biol Blood Marrow Transplant
, vol.19
, pp. 460-467
-
-
Lonial, S.1
Akhtari, M.2
Kaufman, J.3
Torre, C.4
Lechowicz, M.J.5
Flowers, C.6
Sinha, R.7
Khoury, H.J.8
Langston, A.A.9
Waller, E.K.10
-
13
-
-
10344248963
-
A randomized trial comparing the combination of granulocyte-macrophage colony-stimulating factor plus granulocyte colony-stimulating factor versus granulocyte colony-stimulating factor for mobilization of dendritic cell subsets in hematopoietic progenitor cell products
-
15570253
-
Lonial S, Hicks M, Rosenthal H, Langston A, Redei I, Torre C, Duenzl M, Feinstein B, Cherry J, Waller EK. A randomized trial comparing the combination of granulocyte-macrophage colony-stimulating factor plus granulocyte colony-stimulating factor versus granulocyte colony-stimulating factor for mobilization of dendritic cell subsets in hematopoietic progenitor cell products. Biol Blood Marrow Transplant 2004, 10:848-857. 10.1016/j.bbmt.2004.07.008, 15570253.
-
(2004)
Biol Blood Marrow Transplant
, vol.10
, pp. 848-857
-
-
Lonial, S.1
Hicks, M.2
Rosenthal, H.3
Langston, A.4
Redei, I.5
Torre, C.6
Duenzl, M.7
Feinstein, B.8
Cherry, J.9
Waller, E.K.10
-
14
-
-
0034047619
-
Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand
-
Mach N, Gillessen S, Wilson SB, Sheehan C, Mihm M, Dranoff G. Differences in dendritic cells stimulated in vivo by tumors engineered to secrete granulocyte-macrophage colony-stimulating factor or Flt3-ligand. Cancer Res 2000, 60:3239-3246.
-
(2000)
Cancer Res
, vol.60
, pp. 3239-3246
-
-
Mach, N.1
Gillessen, S.2
Wilson, S.B.3
Sheehan, C.4
Mihm, M.5
Dranoff, G.6
-
15
-
-
0032950187
-
Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses
-
Choudhury BA, Liang JC, Thomas EK, Flores-Romo L, Xie QS, Agusala K, Sutaria S, Sinha I, Champlin RE, Claxton DF. Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses. Blood 1999, 93:780-786.
-
(1999)
Blood
, vol.93
, pp. 780-786
-
-
Choudhury, B.A.1
Liang, J.C.2
Thomas, E.K.3
Flores-Romo, L.4
Xie, Q.S.5
Agusala, K.6
Sutaria, S.7
Sinha, I.8
Champlin, R.E.9
Claxton, D.F.10
-
16
-
-
0034096183
-
Cytokine upregulation of the antigen presenting function of acute myeloid leukemia cells
-
10720135
-
Boyer MW, Waller EK, Bray RA, Unangst T, Johnson TS, Phillips C, Jurickova I, Winton EF, Yeager AM. Cytokine upregulation of the antigen presenting function of acute myeloid leukemia cells. Leukemia 2000, 14:412-418. 10.1038/sj.leu.2401685, 10720135.
-
(2000)
Leukemia
, vol.14
, pp. 412-418
-
-
Boyer, M.W.1
Waller, E.K.2
Bray, R.A.3
Unangst, T.4
Johnson, T.S.5
Phillips, C.6
Jurickova, I.7
Winton, E.F.8
Yeager, A.M.9
-
17
-
-
34547464547
-
-
Cambridge, MA: Genzyme Corporation, Leukine® (sargramostim)
-
Leukine® (sargramostim) Full Prescribing Information 2009, Cambridge, MA: Genzyme Corporation, Leukine® (sargramostim).
-
(2009)
Full Prescribing Information
-
-
-
18
-
-
0031569457
-
Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes
-
Ahlers JD, Dunlop N, Alling DW, Nara PL, Berzofsky JA. Cytokine-in-adjuvant steering of the immune response phenotype to HIV-1 vaccine constructs: granulocyte-macrophage colony-stimulating factor and TNF-alpha synergize with IL-12 to enhance induction of cytotoxic T lymphocytes. J Immunol 1997, 158:3947-3958.
-
(1997)
J Immunol
, vol.158
, pp. 3947-3958
-
-
Ahlers, J.D.1
Dunlop, N.2
Alling, D.W.3
Nara, P.L.4
Berzofsky, J.A.5
-
19
-
-
0034234934
-
HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice
-
Reilly RT, Gottlieb MB, Ercolini AM, Machiels JP, Kane CE, Okoye FI, Muller WJ, Dixon KH, Jaffee EM. HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice. Cancer Res 2000, 60:3569-3576.
-
(2000)
Cancer Res
, vol.60
, pp. 3569-3576
-
-
Reilly, R.T.1
Gottlieb, M.B.2
Ercolini, A.M.3
Machiels, J.P.4
Kane, C.E.5
Okoye, F.I.6
Muller, W.J.7
Dixon, K.H.8
Jaffee, E.M.9
-
20
-
-
0035116901
-
The collaboration of both humoral and cellular HER-2/neu-targeted immune responses is required for the complete eradication of HER-2/neu-expressing tumors
-
Reilly RT, Machiels JP, Emens LA, Ercolini AM, Okoye FI, Lei RY, Weintraub D, Jaffee EM. The collaboration of both humoral and cellular HER-2/neu-targeted immune responses is required for the complete eradication of HER-2/neu-expressing tumors. Cancer Res 2001, 61:880-883.
-
(2001)
Cancer Res
, vol.61
, pp. 880-883
-
-
Reilly, R.T.1
Machiels, J.P.2
Emens, L.A.3
Ercolini, A.M.4
Okoye, F.I.5
Lei, R.Y.6
Weintraub, D.7
Jaffee, E.M.8
-
21
-
-
0036005892
-
GM-CSF-based cellular vaccines: a review of the clinical experience
-
11900993
-
Borrello I, Pardoll D. GM-CSF-based cellular vaccines: a review of the clinical experience. Cytokine Growth Factor Rev 2002, 13:185-193. 10.1016/S1359-6101(01)00034-X, 11900993.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 185-193
-
-
Borrello, I.1
Pardoll, D.2
-
22
-
-
34447650649
-
GM-CSF-secreting cancer immunotherapies: preclinical analysis of the mechanism of action
-
17410360
-
Simmons AD, Li B, Gonzalez-Edick M, Lin C, Moskalenko M, Du T, Creson J, VanRoey MJ, Jooss K. GM-CSF-secreting cancer immunotherapies: preclinical analysis of the mechanism of action. Cancer Immunol Immunother 2007, 56:1653-1665. 10.1007/s00262-007-0315-2, 17410360.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1653-1665
-
-
Simmons, A.D.1
Li, B.2
Gonzalez-Edick, M.3
Lin, C.4
Moskalenko, M.5
Du, T.6
Creson, J.7
VanRoey, M.J.8
Jooss, K.9
-
23
-
-
0029849174
-
Active specific immunotherapy of pulmonary metastasis with vaccinia melanoma oncolysate prepared from granulocyte/macrophage-colony-stimulating-factor-gene-encoded vaccinia virus
-
Ju DW, Cao X, Acres B. Active specific immunotherapy of pulmonary metastasis with vaccinia melanoma oncolysate prepared from granulocyte/macrophage-colony-stimulating-factor-gene-encoded vaccinia virus. J Cancer Res Clin Oncol 1996, 122:716-722.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 716-722
-
-
Ju, D.W.1
Cao, X.2
Acres, B.3
-
24
-
-
0031085079
-
Intratumoral injection of GM-CSF gene encoded recombinant vaccinia virus elicits potent antitumor response in a mixture melanoma model
-
Ju DW, Cao X, Acres B. Intratumoral injection of GM-CSF gene encoded recombinant vaccinia virus elicits potent antitumor response in a mixture melanoma model. Cancer Gene Ther 1997, 4:139-144.
-
(1997)
Cancer Gene Ther
, vol.4
, pp. 139-144
-
-
Ju, D.W.1
Cao, X.2
Acres, B.3
-
25
-
-
0034294865
-
Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor
-
11020347
-
Toda M, Martuza RL, Rabkin SD. Tumor growth inhibition by intratumoral inoculation of defective herpes simplex virus vectors expressing granulocyte-macrophage colony-stimulating factor. Mol Ther 2000, 2:324-329. 10.1006/mthe.2000.0130, 11020347.
-
(2000)
Mol Ther
, vol.2
, pp. 324-329
-
-
Toda, M.1
Martuza, R.L.2
Rabkin, S.D.3
-
26
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
-
12595888
-
Liu BL, Robinson M, Han ZQ, Branston RH, English C, Reay P, McGrath Y, Thomas SK, Thornton M, Bullock P, Love CA, Coffin RS. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Gene Ther 2003, 10:292-303. 10.1038/sj.gt.3301885, 12595888.
-
(2003)
Gene Ther
, vol.10
, pp. 292-303
-
-
Liu, B.L.1
Robinson, M.2
Han, Z.Q.3
Branston, R.H.4
English, C.5
Reay, P.6
McGrath, Y.7
Thomas, S.K.8
Thornton, M.9
Bullock, P.10
Love, C.A.11
Coffin, R.S.12
-
27
-
-
63449124514
-
Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor-secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors
-
19208793
-
Li B, VanRoey M, Wang C, Chen TH, Korman A, Jooss K. Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor-secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors. Clin Cancer Res 2009, 15:1623-1634. 10.1158/1078-0432.CCR-08-1825, 19208793.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1623-1634
-
-
Li, B.1
VanRoey, M.2
Wang, C.3
Chen, T.H.4
Korman, A.5
Jooss, K.6
-
28
-
-
33745851479
-
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells
-
1479425, 16778987
-
Quezada SA, Peggs KS, Curran MA, Allison JP. CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells. J Clin Invest 2006, 116:1935-1945. 10.1172/JCI27745, 1479425, 16778987.
-
(2006)
J Clin Invest
, vol.116
, pp. 1935-1945
-
-
Quezada, S.A.1
Peggs, K.S.2
Curran, M.A.3
Allison, J.P.4
-
29
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
3544539, 22658127
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012, 366:2443-2454. 10.1056/NEJMoa1200690, 3544539, 22658127.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
Horn, L.14
Drake, C.G.15
Pardoll, D.M.16
Chen, L.17
Sharfman, W.H.18
Anders, R.A.19
Taube, J.M.20
McMiller, T.L.21
Xu, H.22
Korman, A.J.23
Jure-Kunkel, M.24
Agrawal, S.25
McDonald, D.26
Kollia, G.D.27
Gupta, A.28
Wigginton, J.M.29
Sznol, M.30
more..
-
30
-
-
0033517152
-
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
-
2195583, 10430624
-
van Elsas A, Hurwitz AA, Allison JP. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999, 190:355-366. 10.1084/jem.190.3.355, 2195583, 10430624.
-
(1999)
J Exp Med
, vol.190
, pp. 355-366
-
-
van Elsas, A.1
Hurwitz, A.A.2
Allison, J.P.3
-
31
-
-
78449243489
-
Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade
-
21074057
-
Weber J. Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade. Semin Oncol 2010, 37:430-439. 10.1053/j.seminoncol.2010.09.005, 21074057.
-
(2010)
Semin Oncol
, vol.37
, pp. 430-439
-
-
Weber, J.1
-
32
-
-
33745191473
-
Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect
-
16525479
-
Choi KJ, Kim JH, Lee YS, Kim J, Suh BS, Kim H, Cho S, Sohn JH, Kim GE, Yun CO. Concurrent delivery of GM-CSF and B7-1 using an oncolytic adenovirus elicits potent antitumor effect. Gene Ther 2006, 13:1010-1020. 10.1038/sj.gt.3302759, 16525479.
-
(2006)
Gene Ther
, vol.13
, pp. 1010-1020
-
-
Choi, K.J.1
Kim, J.H.2
Lee, Y.S.3
Kim, J.4
Suh, B.S.5
Kim, H.6
Cho, S.7
Sohn, J.H.8
Kim, G.E.9
Yun, C.O.10
-
33
-
-
34548512807
-
Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb
-
17706463
-
Li B, Lin J, Vanroey M, Jure-Kunkel M, Jooss K. Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb. Clin Immunol 2007, 125:76-87. 10.1016/j.clim.2007.07.005, 17706463.
-
(2007)
Clin Immunol
, vol.125
, pp. 76-87
-
-
Li, B.1
Lin, J.2
Vanroey, M.3
Jure-Kunkel, M.4
Jooss, K.5
-
34
-
-
16844386543
-
Administration of IFN-alpha enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell vaccine
-
15781661
-
Prell RA, Li B, Lin JM, VanRoey M, Jooss K. Administration of IFN-alpha enhances the efficacy of a granulocyte macrophage colony stimulating factor-secreting tumor cell vaccine. Cancer Res 2005, 65:2449-2456. 10.1158/0008-5472.CAN-04-1975, 15781661.
-
(2005)
Cancer Res
, vol.65
, pp. 2449-2456
-
-
Prell, R.A.1
Li, B.2
Lin, J.M.3
VanRoey, M.4
Jooss, K.5
-
35
-
-
10844248144
-
Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy
-
15604233
-
Stagg J, Wu JH, Bouganim N, Galipeau J. Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy. Cancer Res 2004, 64:8795-8799. 10.1158/0008-5472.CAN-04-1776, 15604233.
-
(2004)
Cancer Res
, vol.64
, pp. 8795-8799
-
-
Stagg, J.1
Wu, J.H.2
Bouganim, N.3
Galipeau, J.4
-
36
-
-
33845343558
-
Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy
-
17121902
-
Li B, Lalani AS, Harding TC, Luan B, Koprivnikar K, Huan Tu G, Prell R, VanRoey MJ, Simmons AD, Jooss K. Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. Clin Cancer Res 2006, 12:6808-6816. 10.1158/1078-0432.CCR-06-1558, 17121902.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6808-6816
-
-
Li, B.1
Lalani, A.S.2
Harding, T.C.3
Luan, B.4
Koprivnikar, K.5
Huan Tu, G.6
Prell, R.7
VanRoey, M.J.8
Simmons, A.D.9
Jooss, K.10
-
37
-
-
0033998594
-
Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor
-
Spitler LE, Grossbard ML, Ernstoff MS, Silver G, Jacobs M, Hayes FA, Soong SJ. Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor. J Clin Oncol 2000, 18:1614-1621.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1614-1621
-
-
Spitler, L.E.1
Grossbard, M.L.2
Ernstoff, M.S.3
Silver, G.4
Jacobs, M.5
Hayes, F.A.6
Soong, S.J.7
-
38
-
-
67651151520
-
Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) administered for 3 years as adjuvant therapy of stages II(T4), III, and IV melanoma
-
19483646
-
Spitler LE, Weber RW, Allen RE, Meyer J, Cruickshank S, Garbe E, Lin HY, Soong SJ. Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, sargramostim) administered for 3 years as adjuvant therapy of stages II(T4), III, and IV melanoma. J Immunother 2009, 32:632-637. 10.1097/CJI.0b013e3181a7d60d, 19483646.
-
(2009)
J Immunother
, vol.32
, pp. 632-637
-
-
Spitler, L.E.1
Weber, R.W.2
Allen, R.E.3
Meyer, J.4
Cruickshank, S.5
Garbe, E.6
Lin, H.Y.7
Soong, S.J.8
-
39
-
-
49249101374
-
Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor
-
18591558
-
Daud AI, Mirza N, Lenox B, Andrews S, Urbas P, Gao GX, Lee JH, Sondak VK, Riker AI, Deconti RC, Gabrilovich D. Phenotypic and functional analysis of dendritic cells and clinical outcome in patients with high-risk melanoma treated with adjuvant granulocyte macrophage colony-stimulating factor. J Clin Oncol 2008, 26:3235-3241. 10.1200/JCO.2007.13.9048, 18591558.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3235-3241
-
-
Daud, A.I.1
Mirza, N.2
Lenox, B.3
Andrews, S.4
Urbas, P.5
Gao, G.X.6
Lee, J.H.7
Sondak, V.K.8
Riker, A.I.9
Deconti, R.C.10
Gabrilovich, D.11
-
40
-
-
78449242173
-
E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colonystimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma
-
abstr 8504
-
Lawson DH, Lee SJ, Tarhini AA, Margolin KA, Ernstoff MS, Kirkwood JM. E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colonystimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma. J Clin Oncol 2010, 28:abstr 8504.
-
(2010)
J Clin Oncol
, vol.28
-
-
Lawson, D.H.1
Lee, S.J.2
Tarhini, A.A.3
Margolin, K.A.4
Ernstoff, M.S.5
Kirkwood, J.M.6
-
41
-
-
84859477334
-
Adjuvant GM-CSF therapy for patients with resected stage III/IV melanoma: A retrospective review of a single-center experience
-
abstr 8596
-
Markovic S, Burch PA, LaPlant B, Heun JM, Bradshaw R. Adjuvant GM-CSF therapy for patients with resected stage III/IV melanoma: A retrospective review of a single-center experience. J Clin Oncol 2011, 29:abstr 8596.
-
(2011)
J Clin Oncol
, vol.29
-
-
Markovic, S.1
Burch, P.A.2
LaPlant, B.3
Heun, J.M.4
Bradshaw, R.5
-
42
-
-
46449104245
-
Daily GM-CSF for patients with very high-risk resected melanoma: a pilot trial
-
abstr 2784
-
Isla D, Filipovich E, Mayordomo JI, Andres R, Puig S, Escudero MP, Gallego O, Trujillo R, Revenga F, Alvarez I, Saenz A, Polo E, Tres A. Daily GM-CSF for patients with very high-risk resected melanoma: a pilot trial. Proc Am Soc Clin Oncol 2002, 21:abstr 2784.
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Isla, D.1
Filipovich, E.2
Mayordomo, J.I.3
Andres, R.4
Puig, S.5
Escudero, M.P.6
Gallego, O.7
Trujillo, R.8
Revenga, F.9
Alvarez, I.10
Saenz, A.11
Polo, E.12
Tres, A.13
-
43
-
-
46449135905
-
Sequential administration of GM-CSF (Sargramostim) and IL-2 +/-autologous vaccine as adjuvant therapy in cutaneous melanoma: an interim report of a phase II clinical trial
-
18593361
-
Elias EG, Zapas JL, McCarron EC, Beam SL, Hasskamp JH, Culpepper WJ. Sequential administration of GM-CSF (Sargramostim) and IL-2 +/-autologous vaccine as adjuvant therapy in cutaneous melanoma: an interim report of a phase II clinical trial. Cancer Biother Radiopharm 2008, 23:285-291. 10.1089/cbr.2007.0438, 18593361.
-
(2008)
Cancer Biother Radiopharm
, vol.23
, pp. 285-291
-
-
Elias, E.G.1
Zapas, J.L.2
McCarron, E.C.3
Beam, S.L.4
Hasskamp, J.H.5
Culpepper, W.J.6
-
44
-
-
0029949031
-
Clinical responses and lymphoid infiltrates in metastatic melanoma following treatment with intralesional GM-CSF
-
8819128
-
Si Z, Hersey P, Coates AS. Clinical responses and lymphoid infiltrates in metastatic melanoma following treatment with intralesional GM-CSF. Melanoma Res 1996, 6:247-255. 10.1097/00008390-199606000-00008, 8819128.
-
(1996)
Melanoma Res
, vol.6
, pp. 247-255
-
-
Si, Z.1
Hersey, P.2
Coates, A.S.3
-
45
-
-
0032886907
-
Intradermal injection of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with metastatic melanoma recruits dendritic cells
-
Nasi ML, Lieberman P, Busam KJ, Prieto V, Panageas KS, Lewis JJ, Houghton AN, Chapman PB. Intradermal injection of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with metastatic melanoma recruits dendritic cells. Cytokines Cell Mol Ther 1999, 5:139-144.
-
(1999)
Cytokines Cell Mol Ther
, vol.5
, pp. 139-144
-
-
Nasi, M.L.1
Lieberman, P.2
Busam, K.J.3
Prieto, V.4
Panageas, K.S.5
Lewis, J.J.6
Houghton, A.N.7
Chapman, P.B.8
-
46
-
-
0035720479
-
Perilesional injection of r-GM-CSF in patients with cutaneous melanoma metastases
-
11511318
-
Hoeller C, Jansen B, Heere-Ress E, Pustelnik T, Mossbacher U, Schlagbauer-Wadl H, Wolff K, Pehamberger H. Perilesional injection of r-GM-CSF in patients with cutaneous melanoma metastases. J Invest Dermatol 2001, 117:371-374. 10.1046/j.0022-202x.2001.01427.x, 11511318.
-
(2001)
J Invest Dermatol
, vol.117
, pp. 371-374
-
-
Hoeller, C.1
Jansen, B.2
Heere-Ress, E.3
Pustelnik, T.4
Mossbacher, U.5
Schlagbauer-Wadl, H.6
Wolff, K.7
Pehamberger, H.8
-
47
-
-
0141926517
-
Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer
-
14528078
-
Rao RD, Anderson PM, Arndt CA, Wettstein PJ, Markovic SN. Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer. Am J Clin Oncol 2003, 26:493-498. 10.1097/01.coc.0000037664.04141.D0, 14528078.
-
(2003)
Am J Clin Oncol
, vol.26
, pp. 493-498
-
-
Rao, R.D.1
Anderson, P.M.2
Arndt, C.A.3
Wettstein, P.J.4
Markovic, S.N.5
-
48
-
-
58149230993
-
A dose-escalation study of aerosolized sargramostim in the treatment of metastatic melanoma: an NCCTG Study
-
2694721, 19060590
-
Markovic SN, Suman VJ, Nevala WK, Geeraerts L, Creagan ET, Erickson LA, Rowland KM, Morton RF, Horvath WL, Pittelkow MR. A dose-escalation study of aerosolized sargramostim in the treatment of metastatic melanoma: an NCCTG Study. Am J Clin Oncol 2008, 31:573-579. 10.1097/COC.0b013e318173a536, 2694721, 19060590.
-
(2008)
Am J Clin Oncol
, vol.31
, pp. 573-579
-
-
Markovic, S.N.1
Suman, V.J.2
Nevala, W.K.3
Geeraerts, L.4
Creagan, E.T.5
Erickson, L.A.6
Rowland, K.M.7
Morton, R.F.8
Horvath, W.L.9
Pittelkow, M.R.10
-
49
-
-
56749158015
-
Immunoembolization of malignant liver tumors, including uveal melanoma, using granulocyte-macrophage colony-stimulating factor
-
18838710
-
Sato T, Eschelman DJ, Gonsalves CF, Terai M, Chervoneva I, McCue PA, Shields JA, Shields CL, Yamamoto A, Berd D, Mastrangelo MJ, Sullivan KL. Immunoembolization of malignant liver tumors, including uveal melanoma, using granulocyte-macrophage colony-stimulating factor. J Clin Oncol 2008, 26:5436-5442. 10.1200/JCO.2008.16.0705, 18838710.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5436-5442
-
-
Sato, T.1
Eschelman, D.J.2
Gonsalves, C.F.3
Terai, M.4
Chervoneva, I.5
McCue, P.A.6
Shields, J.A.7
Shields, C.L.8
Yamamoto, A.9
Berd, D.10
Mastrangelo, M.J.11
Sullivan, K.L.12
-
50
-
-
84894889079
-
The results of a randomized phase II study using embolization with or without granulocyte-macrophage colony-stimulating factor (GM-CSF) in uveal melanoma patients with hepatic metastasis
-
abstr 8577
-
Eschelman DJ, Gonsalves CF, Terai M, Laudadio M, Sullivan KL, Mastrangelo MJ, Sato T. The results of a randomized phase II study using embolization with or without granulocyte-macrophage colony-stimulating factor (GM-CSF) in uveal melanoma patients with hepatic metastasis. J Clin Oncol 2011, 29:abstr 8577.
-
(2011)
J Clin Oncol
, vol.29
-
-
Eschelman, D.J.1
Gonsalves, C.F.2
Terai, M.3
Laudadio, M.4
Sullivan, K.L.5
Mastrangelo, M.J.6
Sato, T.7
-
51
-
-
0032744676
-
Regression of in-transit melanoma of the scalp with intralesional recombinant human granulocyte-macrophage colony-stimulating factor
-
10522685
-
Vaquerano JE, Cadbury P, Treseler P, Sagebiel R, Leong SP. Regression of in-transit melanoma of the scalp with intralesional recombinant human granulocyte-macrophage colony-stimulating factor. Arch Dermatol 1999, 135:1276-1277. 10.1001/archderm.135.10.1276, 10522685.
-
(1999)
Arch Dermatol
, vol.135
, pp. 1276-1277
-
-
Vaquerano, J.E.1
Cadbury, P.2
Treseler, P.3
Sagebiel, R.4
Leong, S.P.5
-
52
-
-
0036016473
-
Preliminary experiences of intralesional immunotherapy in cutaneous metastatic melanoma
-
Ridolfi L, Ridolfi R. Preliminary experiences of intralesional immunotherapy in cutaneous metastatic melanoma. Hepatogastroenterology 2002, 49:335-339.
-
(2002)
Hepatogastroenterology
, vol.49
, pp. 335-339
-
-
Ridolfi, L.1
Ridolfi, R.2
-
53
-
-
0031875868
-
A sequential four-drug chemotherapy and biotherapy with interferon alpha and GM-CSF-an innovative protocol for the treatment of metastatic melanoma
-
10850351
-
Schachter J, Rakowsky E, Sulkes A, Adler A. A sequential four-drug chemotherapy and biotherapy with interferon alpha and GM-CSF-an innovative protocol for the treatment of metastatic melanoma. Cancer Biother Radiopharm 1998, 13:155-164. 10.1089/cbr.1998.13.155, 10850351.
-
(1998)
Cancer Biother Radiopharm
, vol.13
, pp. 155-164
-
-
Schachter, J.1
Rakowsky, E.2
Sulkes, A.3
Adler, A.4
-
55
-
-
66249143027
-
Malignant melanoma therapy by chemotherapy and autoimmunity induced by cytokine
-
19409046
-
Jin S, Zhang Q, Kang X, Wang J, Sun W. Malignant melanoma therapy by chemotherapy and autoimmunity induced by cytokine. Cancer Biother Radiopharm 2009, 24:237-241. 10.1089/cbr.2008.0552, 19409046.
-
(2009)
Cancer Biother Radiopharm
, vol.24
, pp. 237-241
-
-
Jin, S.1
Zhang, Q.2
Kang, X.3
Wang, J.4
Sun, W.5
-
56
-
-
74949089360
-
Phase II multicenter trial of maintenance biotherapy after induction concurrent Biochemotherapy for patients with metastatic melanoma
-
19917850
-
O'Day SJ, Atkins MB, Boasberg P, Wang HJ, Thompson JA, Anderson CM, Gonzalez R, Lutzky J, Amatruda T, Hersh EM, Weber JS. Phase II multicenter trial of maintenance biotherapy after induction concurrent Biochemotherapy for patients with metastatic melanoma. J Clin Oncol 2009, 27:6207-6212. 10.1200/JCO.2008.20.3075, 19917850.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6207-6212
-
-
O'Day, S.J.1
Atkins, M.B.2
Boasberg, P.3
Wang, H.J.4
Thompson, J.A.5
Anderson, C.M.6
Gonzalez, R.7
Lutzky, J.8
Amatruda, T.9
Hersh, E.M.10
Weber, J.S.11
-
57
-
-
75549083877
-
A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma
-
19597729
-
Locke F, Clark JI, Gajewski TF. A phase II study of oxaliplatin, docetaxel, and GM-CSF in patients with previously treated advanced melanoma. Cancer Chemother Pharmacol 2010, 65:509-514. 10.1007/s00280-009-1057-y, 19597729.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 509-514
-
-
Locke, F.1
Clark, J.I.2
Gajewski, T.F.3
-
58
-
-
65549133424
-
A phase 1 study of granulocyte macrophage colony-stimulating factor (sargramostim) and escalating doses of thalidomide in patients with high-risk malignant melanoma
-
19307996
-
Lutzky J, Weber R, Nunez Y, Gillett M, Spitler L. A phase 1 study of granulocyte macrophage colony-stimulating factor (sargramostim) and escalating doses of thalidomide in patients with high-risk malignant melanoma. J Immunother 2009, 32:79-85. 10.1097/CJI.0b013e31818c8aaf, 19307996.
-
(2009)
J Immunother
, vol.32
, pp. 79-85
-
-
Lutzky, J.1
Weber, R.2
Nunez, Y.3
Gillett, M.4
Spitler, L.5
-
59
-
-
0033793140
-
GM-CSF with biochemotherapy (cisplatin, DTIC, tamoxifen, IL-2 and interferon-alpha): a phase I trial in melanoma
-
11061616
-
Vaughan MM, Moore J, Riches PG, Johnston SR, A'Hern RP, Hill ME, Eisen T, Ayliffe MJ, Thomas JM, Gore ME. GM-CSF with biochemotherapy (cisplatin, DTIC, tamoxifen, IL-2 and interferon-alpha): a phase I trial in melanoma. Ann Oncol 2000, 11:1183-1189. 10.1023/A:1008348005349, 11061616.
-
(2000)
Ann Oncol
, vol.11
, pp. 1183-1189
-
-
Vaughan, M.M.1
Moore, J.2
Riches, P.G.3
Johnston, S.R.4
A'Hern, R.P.5
Hill, M.E.6
Eisen, T.7
Ayliffe, M.J.8
Thomas, J.M.9
Gore, M.E.10
-
60
-
-
83455220477
-
A phase II study of outpatient chemoimmunotherapy using cisplatin and DTIC followed by GM-CSF, IL-2, and IFN-2b in patients (pts) with metastatic melanoma
-
abstr 2271
-
Gajewski T, Flickinger S. A phase II study of outpatient chemoimmunotherapy using cisplatin and DTIC followed by GM-CSF, IL-2, and IFN-2b in patients (pts) with metastatic melanoma. Proc Am Soc Clin Oncol 2000, 19:abstr 2271.
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
-
-
Gajewski, T.1
Flickinger, S.2
-
61
-
-
84977173641
-
Biochemotherapy (BCT) for stage IV melanoma incorporating temozolomide, decrescendo interleukin-2 (IL-2) and GM-CSF
-
Gibbs P, O'Day S, Richards J, Weber J, Anderson C, Gonzalez R. Biochemotherapy (BCT) for stage IV melanoma incorporating temozolomide, decrescendo interleukin-2 (IL-2) and GM-CSF. Proc Am Soc Clin Oncol 2000, 19:2255.
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 2255
-
-
Gibbs, P.1
O'Day, S.2
Richards, J.3
Weber, J.4
Anderson, C.5
Gonzalez, R.6
-
62
-
-
84977189806
-
Integration of GM-CSF into outpatient chemoimmunotherapy for metastatic melanoma
-
Gong I-Y, Swiger S, Gajewski T. Integration of GM-CSF into outpatient chemoimmunotherapy for metastatic melanoma. Proc Am Soc Clin Oncol 2002, 21:2790.
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
, pp. 2790
-
-
Gong, I.-Y.1
Swiger, S.2
Gajewski, T.3
-
63
-
-
0036451560
-
Phase I/II study of sequential chemoimmunotherapy (SCIT) for metastatic melanoma: outpatient treatment with dacarbazine, granulocyte-macrophage colony-stimulating factor, low-dose interleukin-2, and interferon-alpha
-
12439608
-
Groenewegen G, Bloem A, De Gast GC. Phase I/II study of sequential chemoimmunotherapy (SCIT) for metastatic melanoma: outpatient treatment with dacarbazine, granulocyte-macrophage colony-stimulating factor, low-dose interleukin-2, and interferon-alpha. Cancer Immunol Immunother 2002, 51:630-636. 10.1007/s00262-002-0323-1, 12439608.
-
(2002)
Cancer Immunol Immunother
, vol.51
, pp. 630-636
-
-
Groenewegen, G.1
Bloem, A.2
De Gast, G.C.3
-
64
-
-
0037468096
-
Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma
-
2377058, 12610499
-
de Gast GC, Batchelor D, Kersten MJ, Vyth-Dreese FA, Sein J, van de Kasteele WF, Nooijen WJ, Nieweg OE, de Waal MA, Boogerd W. Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma. Br J Cancer 2003, 88:175-180. 10.1038/sj.bjc.6600717, 2377058, 12610499.
-
(2003)
Br J Cancer
, vol.88
, pp. 175-180
-
-
de Gast, G.C.1
Batchelor, D.2
Kersten, M.J.3
Vyth-Dreese, F.A.4
Sein, J.5
van de Kasteele, W.F.6
Nooijen, W.J.7
Nieweg, O.E.8
de Waal, M.A.9
Boogerd, W.10
-
65
-
-
0037337780
-
Immune effects of escalating doses of granulocyte-macrophage colony-stimulating factor added to a fixed, low-dose, inpatient interleukin-2 regimen: a randomized phase I trial in patients with metastatic melanoma and renal cell carcinoma
-
12616104
-
Smith IJ, Kurt RA, Baher AG, Denman S, Justice L, Doran T, Gilbert M, Alvord WG, Urba WJ. Immune effects of escalating doses of granulocyte-macrophage colony-stimulating factor added to a fixed, low-dose, inpatient interleukin-2 regimen: a randomized phase I trial in patients with metastatic melanoma and renal cell carcinoma. J Immunother 2003, 26:130-138. 10.1097/00002371-200303000-00005, 12616104.
-
(2003)
J Immunother
, vol.26
, pp. 130-138
-
-
Smith, I.J.1
Kurt, R.A.2
Baher, A.G.3
Denman, S.4
Justice, L.5
Doran, T.6
Gilbert, M.7
Alvord, W.G.8
Urba, W.J.9
-
66
-
-
24744458382
-
A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF
-
16100942
-
Lewis KD, Gibbs P, O'Day S, Richards J, Weber J, Anderson C, Zeng C, Baron A, Russ P, Gonzalez R. A phase II study of biochemotherapy for advanced melanoma incorporating temozolomide, decrescendo interleukin-2 and GM-CSF. Cancer Invest 2005, 23:303-308. 10.1081/CNV-58832, 16100942.
-
(2005)
Cancer Invest
, vol.23
, pp. 303-308
-
-
Lewis, K.D.1
Gibbs, P.2
O'Day, S.3
Richards, J.4
Weber, J.5
Anderson, C.6
Zeng, C.7
Baron, A.8
Russ, P.9
Gonzalez, R.10
-
67
-
-
33644805723
-
Low-dose outpatient chemobiotherapy with temozolomide, granulocyte-macrophage colony stimulating factor, interferon-alpha2b, and recombinant interleukin-2 for the treatment of metastatic melanoma
-
16260693
-
Weber RW, O'Day S, Rose M, Deck R, Ames P, Good J, Meyer J, Allen R, Trautvetter S, Timmerman M, Cruickshank S, Cook M, Gonzalez R, Spitler LE. Low-dose outpatient chemobiotherapy with temozolomide, granulocyte-macrophage colony stimulating factor, interferon-alpha2b, and recombinant interleukin-2 for the treatment of metastatic melanoma. J Clin Oncol 2005, 23:8992-9000. 10.1200/JCO.2005.02.5791, 16260693.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8992-9000
-
-
Weber, R.W.1
O'Day, S.2
Rose, M.3
Deck, R.4
Ames, P.5
Good, J.6
Meyer, J.7
Allen, R.8
Trautvetter, S.9
Timmerman, M.10
Cruickshank, S.11
Cook, M.12
Gonzalez, R.13
Spitler, L.E.14
-
68
-
-
77949881923
-
Cytokine working group study of lymphodepleting chemotherapy, interleukin-2, and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma: clinical outcomes and peripheral-blood cell recovery
-
2834469, 20124177
-
Gunturu KS, Meehan KR, Mackenzie TA, Crocenzi TS, McDermott D, Usherwood EJ, Margolin KA, Crosby NA, Atkins MB, Turk MJ, Ahonen C, Fuse S, Clark JI, Fisher JL, Noelle RJ, Ernstoff MS. Cytokine working group study of lymphodepleting chemotherapy, interleukin-2, and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma: clinical outcomes and peripheral-blood cell recovery. J Clin Oncol 2010, 28:1196-1202. 10.1200/JCO.2009.24.8153, 2834469, 20124177.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1196-1202
-
-
Gunturu, K.S.1
Meehan, K.R.2
Mackenzie, T.A.3
Crocenzi, T.S.4
McDermott, D.5
Usherwood, E.J.6
Margolin, K.A.7
Crosby, N.A.8
Atkins, M.B.9
Turk, M.J.10
Ahonen, C.11
Fuse, S.12
Clark, J.I.13
Fisher, J.L.14
Noelle, R.J.15
Ernstoff, M.S.16
-
69
-
-
79251496050
-
Phase II trial of high-dose interleukin-2 (IL-2) with priming and concomitant sargramostim (GM-CSF) in patients with advanced melanoma
-
abstr 8560
-
Lutzky J, Lawson DH, Enriquez-Nunez Y, Gabrilovich D. Phase II trial of high-dose interleukin-2 (IL-2) with priming and concomitant sargramostim (GM-CSF) in patients with advanced melanoma. J Clin Oncol 2010, 28:abstr 8560.
-
(2010)
J Clin Oncol
, vol.28
-
-
Lutzky, J.1
Lawson, D.H.2
Enriquez-Nunez, Y.3
Gabrilovich, D.4
-
70
-
-
77953720628
-
In situ regulation of DC subsets and T cells mediates tumor regression in mice
-
2872791, 20368186
-
Ali OA, Emerich D, Dranoff G, Mooney DJ. In situ regulation of DC subsets and T cells mediates tumor regression in mice. Sci Transl Med 2009, 1:8ra19. 2872791, 20368186.
-
(2009)
Sci Transl Med
, vol.1
, pp. 8ra19
-
-
Ali, O.A.1
Emerich, D.2
Dranoff, G.3
Mooney, D.J.4
-
71
-
-
72549086588
-
Effect of granulocyte/macrophage colony-stimulating factor on vaccination with an allogeneic whole-cell melanoma vaccine
-
2920049, 19903777
-
Faries MB, Hsueh EC, Ye X, Hoban M, Morton DL. Effect of granulocyte/macrophage colony-stimulating factor on vaccination with an allogeneic whole-cell melanoma vaccine. Clin Cancer Res 2009, 15:7029-7035. 10.1158/1078-0432.CCR-09-1540, 2920049, 19903777.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7029-7035
-
-
Faries, M.B.1
Hsueh, E.C.2
Ye, X.3
Hoban, M.4
Morton, D.L.5
-
72
-
-
0642311904
-
Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
-
14581425
-
Slingluff CL, Petroni GR, Yamshchikov GV, Barnd DL, Eastham S, Galavotti H, Patterson JW, Deacon DH, Hibbitts S, Teates D, Neese PY, Grosh WW, Chianese-Bullock KA, Woodson EM, Wiernasz CJ, Merrill P, Gibson J, Ross M, Engelhard VH. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J Clin Oncol 2003, 21:4016-4026. 10.1200/JCO.2003.10.005, 14581425.
-
(2003)
J Clin Oncol
, vol.21
, pp. 4016-4026
-
-
Slingluff, C.L.1
Petroni, G.R.2
Yamshchikov, G.V.3
Barnd, D.L.4
Eastham, S.5
Galavotti, H.6
Patterson, J.W.7
Deacon, D.H.8
Hibbitts, S.9
Teates, D.10
Neese, P.Y.11
Grosh, W.W.12
Chianese-Bullock, K.A.13
Woodson, E.M.14
Wiernasz, C.J.15
Merrill, P.16
Gibson, J.17
Ross, M.18
Engelhard, V.H.19
-
73
-
-
84864662070
-
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
-
22842478
-
Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, Staehler M, Brugger W, Dietrich PY, Mendrzyk R, Hilf N, Schoor O, Fritsche J, Mahr A, Maurer D, Vass V, Trautwein C, Lewandrowski P, Flohr C, Pohla H, Stanczak JJ, Bronte V, Mandruzzato S, Biedermann T, Pawelec G, Derhovanessian E, Yamagishi H, Miki T, Hongo F, Takaha N, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med 2012, 18:1254-1261. 10.1038/nm.2883, 22842478.
-
(2012)
Nat Med
, vol.18
, pp. 1254-1261
-
-
Walter, S.1
Weinschenk, T.2
Stenzl, A.3
Zdrojowy, R.4
Pluzanska, A.5
Szczylik, C.6
Staehler, M.7
Brugger, W.8
Dietrich, P.Y.9
Mendrzyk, R.10
Hilf, N.11
Schoor, O.12
Fritsche, J.13
Mahr, A.14
Maurer, D.15
Vass, V.16
Trautwein, C.17
Lewandrowski, P.18
Flohr, C.19
Pohla, H.20
Stanczak, J.J.21
Bronte, V.22
Mandruzzato, S.23
Biedermann, T.24
Pawelec, G.25
Derhovanessian, E.26
Yamagishi, H.27
Miki, T.28
Hongo, F.29
Takaha, N.30
more..
-
74
-
-
20044373641
-
MAGE-A1-, MAGE-A10-, and gp100-derived peptides are immunogenic when combined with granulocyte-macrophage colony-stimulating factor and montanide ISA-51 adjuvant and administered as part of a multipeptide vaccine for melanoma
-
15728523
-
Chianese-Bullock KA, Pressley J, Garbee C, Hibbitts S, Murphy C, Yamshchikov G, Petroni GR, Bissonette EA, Neese PY, Grosh WW, Merrill P, Fink R, Woodson EM, Wiernasz CJ, Patterson JW, Slingluff CL. MAGE-A1-, MAGE-A10-, and gp100-derived peptides are immunogenic when combined with granulocyte-macrophage colony-stimulating factor and montanide ISA-51 adjuvant and administered as part of a multipeptide vaccine for melanoma. J Immunol 2005, 174:3080-3086. 10.4049/jimmunol.174.5.3080, 15728523.
-
(2005)
J Immunol
, vol.174
, pp. 3080-3086
-
-
Chianese-Bullock, K.A.1
Pressley, J.2
Garbee, C.3
Hibbitts, S.4
Murphy, C.5
Yamshchikov, G.6
Petroni, G.R.7
Bissonette, E.A.8
Neese, P.Y.9
Grosh, W.W.10
Merrill, P.11
Fink, R.12
Woodson, E.M.13
Wiernasz, C.J.14
Patterson, J.W.15
Slingluff, C.L.16
-
75
-
-
0037457311
-
Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the T-cell response to vaccination with tyrosinase peptides
-
12569574
-
Scheibenbogen C, Schadendorf D, Bechrakis NE, Nagorsen D, Hofmann U, Servetopoulou F, Letsch A, Philipp A, Foerster MH, Schmittel A, Thiel E, Keilholz U. Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the T-cell response to vaccination with tyrosinase peptides. Int J Cancer 2003, 104:188-194. 10.1002/ijc.10961, 12569574.
-
(2003)
Int J Cancer
, vol.104
, pp. 188-194
-
-
Scheibenbogen, C.1
Schadendorf, D.2
Bechrakis, N.E.3
Nagorsen, D.4
Hofmann, U.5
Servetopoulou, F.6
Letsch, A.7
Philipp, A.8
Foerster, M.H.9
Schmittel, A.10
Thiel, E.11
Keilholz, U.12
-
76
-
-
0034064242
-
Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma
-
10746554
-
Scheibenbogen C, Schmittel A, Keilholz U, Allgauer T, Hofmann U, Max R, Thiel E, Schadendorf D. Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma. J Immunother 2000, 23:275-281. 10.1097/00002371-200003000-00012, 10746554.
-
(2000)
J Immunother
, vol.23
, pp. 275-281
-
-
Scheibenbogen, C.1
Schmittel, A.2
Keilholz, U.3
Allgauer, T.4
Hofmann, U.5
Max, R.6
Thiel, E.7
Schadendorf, D.8
-
77
-
-
0041485051
-
Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo
-
8690525
-
Jager E, Ringhoffer M, Dienes HP, Arand M, Karbach J, Jager D, Ilsemann C, Hagedorn M, Oesch F, Knuth A. Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo. Int J Cancer 1996, 67:54-62. 10.1002/(SICI)1097-0215(19960703)67:1<54::AID-IJC11>3.0.CO;2-C, 8690525.
-
(1996)
Int J Cancer
, vol.67
, pp. 54-62
-
-
Jager, E.1
Ringhoffer, M.2
Dienes, H.P.3
Arand, M.4
Karbach, J.5
Jager, D.6
Ilsemann, C.7
Hagedorn, M.8
Oesch, F.9
Knuth, A.10
-
78
-
-
63149171153
-
Immunogenicity and antitumor effects of vaccination with peptide vaccine+/-granulocyte-monocyte colony-stimulating factor and/or IFN-alpha2b in advanced metastatic melanoma: Eastern Cooperative Oncology Group Phase II Trial E1696
-
2759898, 19228745
-
Kirkwood JM, Lee S, Moschos SJ, Albertini MR, Michalak JC, Sander C, Whiteside T, Butterfield LH, Weiner L. Immunogenicity and antitumor effects of vaccination with peptide vaccine+/-granulocyte-monocyte colony-stimulating factor and/or IFN-alpha2b in advanced metastatic melanoma: Eastern Cooperative Oncology Group Phase II Trial E1696. Clin Cancer Res 2009, 15:1443-1451. 10.1158/1078-0432.CCR-08-1231, 2759898, 19228745.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1443-1451
-
-
Kirkwood, J.M.1
Lee, S.2
Moschos, S.J.3
Albertini, M.R.4
Michalak, J.C.5
Sander, C.6
Whiteside, T.7
Butterfield, L.H.8
Weiner, L.9
-
79
-
-
0141576738
-
Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma
-
12947071
-
Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Mihm M, Dranoff G. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J Clin Oncol 2003, 21:3343-3350. 10.1200/JCO.2003.07.005, 12947071.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3343-3350
-
-
Soiffer, R.1
Hodi, F.S.2
Haluska, F.3
Jung, K.4
Gillessen, S.5
Singer, S.6
Tanabe, K.7
Duda, R.8
Mentzer, S.9
Jaklitsch, M.10
Bueno, R.11
Clift, S.12
Hardy, S.13
Neuberg, D.14
Mulligan, R.15
Webb, I.16
Mihm, M.17
Dranoff, G.18
-
80
-
-
0032573225
-
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma
-
23738, 9789055
-
Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC, Hodi FS, Liebster L, Lam P, Mentzer S, Singer S, Tanabe KK, Cosimi AB, Duda R, Sober A, Bhan A, Daley J, Neuberg D, Parry G, Rokovich J, Richards L, Drayer J, Berns A, Clift S, Cohen LK, Mulligan RC, Dranoff G. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci USA 1998, 95:13141-13146. 10.1073/pnas.95.22.13141, 23738, 9789055.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13141-13146
-
-
Soiffer, R.1
Lynch, T.2
Mihm, M.3
Jung, K.4
Rhuda, C.5
Schmollinger, J.C.6
Hodi, F.S.7
Liebster, L.8
Lam, P.9
Mentzer, S.10
Singer, S.11
Tanabe, K.K.12
Cosimi, A.B.13
Duda, R.14
Sober, A.15
Bhan, A.16
Daley, J.17
Neuberg, D.18
Parry, G.19
Rokovich, J.20
Richards, L.21
Drayer, J.22
Berns, A.23
Clift, S.24
Cohen, L.K.25
Mulligan, R.C.26
Dranoff, G.27
more..
-
81
-
-
72549116845
-
Effect of granulocyte/macrophage colony-stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial
-
2778314, 19903780
-
Slingluff CL, Petroni GR, Olson WC, Smolkin ME, Ross MI, Haas NB, Grosh WW, Boisvert ME, Kirkwood JM, Chianese-Bullock KA. Effect of granulocyte/macrophage colony-stimulating factor on circulating CD8+ and CD4+ T-cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial. Clin Cancer Res 2009, 15:7036-7044. 10.1158/1078-0432.CCR-09-1544, 2778314, 19903780.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7036-7044
-
-
Slingluff, C.L.1
Petroni, G.R.2
Olson, W.C.3
Smolkin, M.E.4
Ross, M.I.5
Haas, N.B.6
Grosh, W.W.7
Boisvert, M.E.8
Kirkwood, J.M.9
Chianese-Bullock, K.A.10
-
82
-
-
84862815799
-
Function but not phenotype of melanoma peptide-specific CD8(+) T cells correlate with survival in a multiepitope peptide vaccine trial (ECOG 1696)
-
3658448, 22021080
-
Schaefer C, Butterfield LH, Lee S, Kim GG, Visus C, Albers A, Kirkwood JM, Whiteside TL. Function but not phenotype of melanoma peptide-specific CD8(+) T cells correlate with survival in a multiepitope peptide vaccine trial (ECOG 1696). Int J Cancer 2012, 131:874-884. 10.1002/ijc.26481, 3658448, 22021080.
-
(2012)
Int J Cancer
, vol.131
, pp. 874-884
-
-
Schaefer, C.1
Butterfield, L.H.2
Lee, S.3
Kim, G.G.4
Visus, C.5
Albers, A.6
Kirkwood, J.M.7
Whiteside, T.L.8
-
83
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
17577033
-
Filipazzi P, Valenti R, Huber V, Pilla L, Canese P, Iero M, Castelli C, Mariani L, Parmiani G, Rivoltini L. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 2007, 25:2546-2553. 10.1200/JCO.2006.08.5829, 17577033.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
Pilla, L.4
Canese, P.5
Iero, M.6
Castelli, C.7
Mariani, L.8
Parmiani, G.9
Rivoltini, L.10
-
84
-
-
33847258205
-
Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
-
Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann Oncol 2007, 18:226-232.
-
(2007)
Ann Oncol
, vol.18
, pp. 226-232
-
-
Parmiani, G.1
Castelli, C.2
Pilla, L.3
Santinami, M.4
Colombo, M.P.5
Rivoltini, L.6
-
85
-
-
77955104827
-
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck
-
20670951
-
Harrington KJ, Hingorani M, Tanay MA, Hickey J, Bhide SA, Clarke PM, Renouf LC, Thway K, Sibtain A, McNeish IA, Newbold KL, Goldsweig H, Coffin R, Nutting CM. Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck. Clin Cancer Res 2010, 16:4005-4015. 10.1158/1078-0432.CCR-10-0196, 20670951.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4005-4015
-
-
Harrington, K.J.1
Hingorani, M.2
Tanay, M.A.3
Hickey, J.4
Bhide, S.A.5
Clarke, P.M.6
Renouf, L.C.7
Thway, K.8
Sibtain, A.9
McNeish, I.A.10
Newbold, K.L.11
Goldsweig, H.12
Coffin, R.13
Nutting, C.M.14
-
86
-
-
33845336115
-
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
-
17121894
-
Hu JCC, Coffin RS, Davis CJ. A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res 2006, 12:6737-6747. 10.1158/1078-0432.CCR-06-0759, 17121894.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6737-6747
-
-
Hu, J.C.C.1
Coffin, R.S.2
Davis, C.J.3
-
87
-
-
77149141965
-
Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
-
19915919
-
Kaufman HL, Kim DW, DeRaffele G, Mitcham J, Coffin RS, Kim-Schulze S. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann Surg Oncol 2010, 17:718-730. 10.1245/s10434-009-0809-6, 19915919.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 718-730
-
-
Kaufman, H.L.1
Kim, D.W.2
DeRaffele, G.3
Mitcham, J.4
Coffin, R.S.5
Kim-Schulze, S.6
-
88
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma
-
19884534
-
Senzer NN, Kaufman HL, Amatruda T, Nemunaitis M, Reid T, Daniels G, Gonzalez R, Glaspy J, Whitman E, Harrington K, Goldsweig H, Marshall T, Love C, Coffin R, Nemunaitis JJ. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol 2009, 27:5763-5771. 10.1200/JCO.2009.24.3675, 19884534.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5763-5771
-
-
Senzer, N.N.1
Kaufman, H.L.2
Amatruda, T.3
Nemunaitis, M.4
Reid, T.5
Daniels, G.6
Gonzalez, R.7
Glaspy, J.8
Whitman, E.9
Harrington, K.10
Goldsweig, H.11
Marshall, T.12
Love, C.13
Coffin, R.14
Nemunaitis, J.J.15
-
89
-
-
84884594361
-
OPTiM: A randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma
-
abstr LBA9008
-
Andtbacka RHI, Collichio FA, Amatruda T, Senzer NN, Chesney J, Delman KA, Spitler LE, Puzanov I, Doleman S, Ye Y, Vanderwalde AM, Coffin R, Kaufman H. OPTiM: A randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma. J Clin Oncol 2013, 31:abstr LBA9008.
-
(2013)
J Clin Oncol
, vol.31
-
-
Andtbacka, R.H.I.1
Collichio, F.A.2
Amatruda, T.3
Senzer, N.N.4
Chesney, J.5
Delman, K.A.6
Spitler, L.E.7
Puzanov, I.8
Doleman, S.9
Ye, Y.10
Vanderwalde, A.M.11
Coffin, R.12
Kaufman, H.13
-
90
-
-
84880263903
-
Multicenter, randomized phase II trial of GM-CSF (GM) plus ipilimumab (Ipi) versus Ipi alone in metastatic melanoma: E1608
-
abstr CRA9007
-
Hodi FS, Lee SJ, McDermott DF, Rao UNM, Butterfield LH, Tarhini AA, Leming PD, Puzanov I, Kirkwood JM. Multicenter, randomized phase II trial of GM-CSF (GM) plus ipilimumab (Ipi) versus Ipi alone in metastatic melanoma: E1608. J Clin Oncol 2013, 31:abstr CRA9007.
-
(2013)
J Clin Oncol
, vol.31
-
-
Hodi, F.S.1
Lee, S.J.2
McDermott, D.F.3
Rao, U.N.M.4
Butterfield, L.H.5
Tarhini, A.A.6
Leming, P.D.7
Puzanov, I.8
Kirkwood, J.M.9
-
91
-
-
79957902460
-
Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy
-
3129795, 21427706
-
Heo J, Breitbach CJ, Moon A, Kim CW, Patt R, Kim MK, Lee YK, Oh SY, Woo HY, Parato K, Rintoul J, Falls T, Hickman T, Rhee BG, Bell JC, Kirn DH, Hwang TH. Sequential therapy with JX-594, a targeted oncolytic poxvirus, followed by sorafenib in hepatocellular carcinoma: preclinical and clinical demonstration of combination efficacy. Mol Ther 2011, 19:1170-1179. 10.1038/mt.2011.39, 3129795, 21427706.
-
(2011)
Mol Ther
, vol.19
, pp. 1170-1179
-
-
Heo, J.1
Breitbach, C.J.2
Moon, A.3
Kim, C.W.4
Patt, R.5
Kim, M.K.6
Lee, Y.K.7
Oh, S.Y.8
Woo, H.Y.9
Parato, K.10
Rintoul, J.11
Falls, T.12
Hickman, T.13
Rhee, B.G.14
Bell, J.C.15
Kirn, D.H.16
Hwang, T.H.17
-
92
-
-
52049090425
-
Phase 1/2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer
-
18646045
-
Higano CS, Corman JM, Smith DC, Centeno AS, Steidle CP, Gittleman M, Simons JW, Sacks N, Aimi J, Small EJ. Phase 1/2 dose-escalation study of a GM-CSF-secreting, allogeneic, cellular immunotherapy for metastatic hormone-refractory prostate cancer. Cancer 2008, 113:975-984. 10.1002/cncr.23669, 18646045.
-
(2008)
Cancer
, vol.113
, pp. 975-984
-
-
Higano, C.S.1
Corman, J.M.2
Smith, D.C.3
Centeno, A.S.4
Steidle, C.P.5
Gittleman, M.6
Simons, J.W.7
Sacks, N.8
Aimi, J.9
Small, E.J.10
-
93
-
-
78650385895
-
Active immunotherapy induces antibody responses that target tumor angiogenesis
-
3057563, 21159637
-
Schoenfeld J, Jinushi M, Nakazaki Y, Wiener D, Park J, Soiffer R, Neuberg D, Mihm M, Hodi FS, Dranoff G. Active immunotherapy induces antibody responses that target tumor angiogenesis. Cancer Res 2010, 70:10150-10160. 10.1158/0008-5472.CAN-10-1852, 3057563, 21159637.
-
(2010)
Cancer Res
, vol.70
, pp. 10150-10160
-
-
Schoenfeld, J.1
Jinushi, M.2
Nakazaki, Y.3
Wiener, D.4
Park, J.5
Soiffer, R.6
Neuberg, D.7
Mihm, M.8
Hodi, F.S.9
Dranoff, G.10
-
94
-
-
84857782004
-
Phase I trial of " bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer
-
3293620, 22186789
-
Senzer N, Barve M, Kuhn J, Melnyk A, Beitsch P, Lazar M, Lifshitz S, Magee M, Oh J, Mill SW, Bedell C, Higgs C, Kumar P, Yu Y, Norvell F, Phalon C, Taquet N, Rao DD, Wang Z, Jay CM, Pappen BO, Wallraven G, Brunicardi FC, Shanahan DM, Maples PB, Nemunaitis J. Phase I trial of " bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancer. Mol Ther 2012, 20:679-686. 10.1038/mt.2011.269, 3293620, 22186789.
-
(2012)
Mol Ther
, vol.20
, pp. 679-686
-
-
Senzer, N.1
Barve, M.2
Kuhn, J.3
Melnyk, A.4
Beitsch, P.5
Lazar, M.6
Lifshitz, S.7
Magee, M.8
Oh, J.9
Mill, S.W.10
Bedell, C.11
Higgs, C.12
Kumar, P.13
Yu, Y.14
Norvell, F.15
Phalon, C.16
Taquet, N.17
Rao, D.D.18
Wang, Z.19
Jay, C.M.20
Pappen, B.O.21
Wallraven, G.22
Brunicardi, F.C.23
Shanahan, D.M.24
Maples, P.B.25
Nemunaitis, J.26
more..
-
95
-
-
77649270825
-
Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma
-
2839441, 19935776
-
Adamina M, Rosenthal R, Weber WP, Frey DM, Viehl CT, Bolli M, Huegli RW, Jacob AL, Heberer M, Oertli D, Marti W, Spagnoli GC, Zajac P. Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and costimulatory molecules in metastatic melanoma. Mol Ther 2010, 18:651-659. 10.1038/mt.2009.275, 2839441, 19935776.
-
(2010)
Mol Ther
, vol.18
, pp. 651-659
-
-
Adamina, M.1
Rosenthal, R.2
Weber, W.P.3
Frey, D.M.4
Viehl, C.T.5
Bolli, M.6
Huegli, R.W.7
Jacob, A.L.8
Heberer, M.9
Oertli, D.10
Marti, W.11
Spagnoli, G.C.12
Zajac, P.13
-
96
-
-
67651152679
-
Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients
-
19609242
-
Weide B, Pascolo S, Scheel B, Derhovanessian E, Pflugfelder A, Eigentler TK, Pawelec G, Hoerr I, Rammensee HG, Garbe C. Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients. J Immunother 2009, 32:498-507. 10.1097/CJI.0b013e3181a00068, 19609242.
-
(2009)
J Immunother
, vol.32
, pp. 498-507
-
-
Weide, B.1
Pascolo, S.2
Scheel, B.3
Derhovanessian, E.4
Pflugfelder, A.5
Eigentler, T.K.6
Pawelec, G.7
Hoerr, I.8
Rammensee, H.G.9
Garbe, C.10
-
97
-
-
84866665586
-
Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma
-
22996370
-
Dillman RO, Cornforth AN, Depriest C, McClay EF, Amatruda TT, de Leon C, Ellis RE, Mayorga C, Carbonell D, Cubellis JM. Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma. J Immunother 2012, 35:641-649. 10.1097/CJI.0b013e31826f79c8, 22996370.
-
(2012)
J Immunother
, vol.35
, pp. 641-649
-
-
Dillman, R.O.1
Cornforth, A.N.2
Depriest, C.3
McClay, E.F.4
Amatruda, T.T.5
de Leon, C.6
Ellis, R.E.7
Mayorga, C.8
Carbonell, D.9
Cubellis, J.M.10
-
98
-
-
56749170720
-
Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma
-
3909666, 18797450
-
Perales MA, Yuan J, Powel S, Gallardo HF, Rasalan TS, Gonzalez C, Manukian G, Wang J, Zhang Y, Chapman PB, Krown SE, Livingston PO, Ejadi S, Panageas KS, Engelhorn ME, Terzulli SL, Houghton AN, Wolchok JD. Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma. Mol Ther 2008, 16:2022-2029. 10.1038/mt.2008.196, 3909666, 18797450.
-
(2008)
Mol Ther
, vol.16
, pp. 2022-2029
-
-
Perales, M.A.1
Yuan, J.2
Powel, S.3
Gallardo, H.F.4
Rasalan, T.S.5
Gonzalez, C.6
Manukian, G.7
Wang, J.8
Zhang, Y.9
Chapman, P.B.10
Krown, S.E.11
Livingston, P.O.12
Ejadi, S.13
Panageas, K.S.14
Engelhorn, M.E.15
Terzulli, S.L.16
Houghton, A.N.17
Wolchok, J.D.18
|