-
1
-
-
84877669593
-
The basic principles of chimeric antigen receptor design
-
Sadelain M, Brentjens R, Riviere I. The basic principles of chimeric antigen receptor design. Cancer Discov. 2013;3:388-398.
-
(2013)
Cancer Discov.
, vol.3
, pp. 388-398
-
-
Sadelain, M.1
Brentjens, R.2
Riviere, I.3
-
3
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
Rosenberg SA, Restifo NP, Yang JC, et al. Adoptive cell transfer: a clinical path to effective cancer immunotherapy. Nat Rev Cancer. 2008;8:299-308.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
-
4
-
-
0030810446
-
Genetic treatment of the haemoglobinopathies: Recombinations and new combinations
-
Sadelain M. Genetic treatment of the haemoglobinopathies: recombinations and new combinations. Br J Haematol. 1997;98:247-253.
-
(1997)
Br J Haematol
, vol.98
, pp. 247-253
-
-
Sadelain, M.1
-
5
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter DL, Levine BL, KalosM, et al. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med. 2011;365:725-733.
-
(2011)
N Engl J Med
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
Levine, B.L.2
Kalos, M.3
-
6
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp SA, Kalos M, Barrett D, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med. 2013;368:1509-1518.
-
(2013)
N Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
7
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
Brentjens RJ, Riviere I, Park JH, et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood. 2011;118:4817-4828.
-
(2011)
Blood
, vol.118
, pp. 4817-4828
-
-
Brentjens, R.J.1
Riviere, I.2
Park, J.H.3
-
8
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer JN, Dudley ME, Feldman SA, et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood. 2012;119:2709-2720.
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
9
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28:4722-4729.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
10
-
-
66349117960
-
CAR mechanics: Driving T cells into the MUC of cancer
-
Maher J, Wilkie S. CAR mechanics: driving T cells into the MUC of cancer. Cancer Res. 2009;69:4559-4562.
-
(2009)
Cancer Res
, vol.69
, pp. 4559-4562
-
-
Maher, J.1
Wilkie, S.2
-
11
-
-
84862513344
-
Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy
-
Gan HK, Burgess AW, Clayton AH, et al. Targeting of a conformationally exposed, tumor-specific epitope of EGFR as a strategy for cancer therapy. Cancer Res. 2012;72:2924-2930.
-
(2012)
Cancer Res
, vol.72
, pp. 2924-2930
-
-
Gan, H.K.1
Burgess, A.W.2
Clayton, A.H.3
-
12
-
-
10744228315
-
Differential EphA2 epitope display on normal versus malignant cells
-
Coffman KT, Hu M, Carles-Kinch K, et al. Differential EphA2 epitope display on normal versus malignant cells. Cancer Res. 2003;63:7907-7912.
-
(2003)
Cancer Res
, vol.63
, pp. 7907-7912
-
-
Coffman, K.T.1
Hu, M.2
Carles-Kinch, K.3
-
13
-
-
77954748206
-
Prostate stem cell antigen: A Jekyll and Hyde molecule?
-
Saeki N, Gu J, Yoshida T, et al. Prostate stem cell antigen: a Jekyll and Hyde molecule? Clin Cancer Res. 2010;16:3533-3538.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3533-3538
-
-
Saeki, N.1
Gu, J.2
Yoshida, T.3
-
14
-
-
79952304769
-
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
-
Robbins PF, Morgan RA, Feldman SA, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol. 2011;29:917-924.
-
(2011)
J Clin Oncol
, vol.29
, pp. 917-924
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
-
15
-
-
84873991752
-
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
-
Morgan RA, Chinnasamy N, Abate-Daga D, et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunother. 2013;36:133-151.
-
(2013)
J Immunother
, vol.36
, pp. 133-151
-
-
Morgan, R.A.1
Chinnasamy, N.2
Abate-Daga, D.3
-
16
-
-
0035186913
-
A phage display selected fab fragment with MHC class I-restricted specificity forMAGE-A1 allows for retargeting of primary human T lymphocytes
-
Willemsen RA, Debets R, Hart E, et al. A phage display selected fab fragment with MHC class I-restricted specificity forMAGE-A1 allows for retargeting of primary human T lymphocytes. Gene Ther. 2001;8:1601-1608.
-
(2001)
Gene Ther.
, vol.8
, pp. 1601-1608
-
-
Willemsen, R.A.1
Debets, R.2
Hart, E.3
-
17
-
-
84872196489
-
Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
-
Kloss CC, Condomines M, Cartellieri M, et al. Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat Biotechnol. 2013;31:71-75.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 71-75
-
-
Kloss, C.C.1
Condomines, M.2
Cartellieri, M.3
-
18
-
-
84866740895
-
Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling
-
Wilkie S, van Schalkwyk MC, Hobbs S, et al. Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling.JClin Immunol. 2012;32:1059-1070.
-
(2012)
JClin Immunol
, vol.32
, pp. 1059-1070
-
-
Wilkie, S.1
Van Schalkwyk, M.C.2
Hobbs, S.3
-
19
-
-
84890174110
-
Chimeric antigen receptor T cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo
-
Lanitis E, Poussin M, Klattenhof A, et al. Chimeric antigen receptor T cells with dissociated signaling domains exhibit focused antitumor activity with reduced potential for toxicity in vivo. Cancer Immunol Res. 2013;1:43-53.
-
(2013)
Cancer Immunol Res.
, vol.1
, pp. 43-53
-
-
Lanitis, E.1
Poussin, M.2
Klattenhof, A.3
-
20
-
-
84880259439
-
TanCAR: A novel bispecific chimeric antigen receptor for cancer immunotherapy
-
Grada Z, Hegde M, Byrd T, et al. TanCAR: a novel bispecific chimeric antigen receptor for cancer immunotherapy. Mol Ther Nucleic Acids. 2013;2:e105.
-
(2013)
Mol Ther Nucleic Acids.
, vol.2
-
-
Grada, Z.1
Hegde, M.2
Byrd, T.3
-
21
-
-
84859383718
-
A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor
-
Urbanska K, Lanitis E, Poussin M, et al. A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor. Cancer Res. 2012;72:1844-1852.
-
(2012)
Cancer Res.
, vol.72
, pp. 1844-1852
-
-
Urbanska, K.1
Lanitis, E.2
Poussin, M.3
-
22
-
-
84870309981
-
Redirecting gene-modified T cells toward various cancer types using tagged antibodies
-
Tamada K, Geng D, Sakoda Y, et al. Redirecting gene-modified T cells toward various cancer types using tagged antibodies. Clin Cancer Res. 2012;18:6436-6445.
-
(2012)
Clin Cancer Res.
, vol.18
, pp. 6436-6445
-
-
Tamada, K.1
Geng, D.2
Sakoda, Y.3
-
23
-
-
0037058993
-
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
-
Yee C, Thompson JA, Byrd D, et al. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc Natl Acad Sci U S A. 2002;99:16168-16173.
-
(2002)
Proc Natl Acad Sci U S A.
, vol.99
, pp. 16168-16173
-
-
Yee, C.1
Thompson, J.A.2
Byrd, D.3
-
24
-
-
84887474711
-
Reassessing target antigens for adoptive T-cell therapy
-
Hinrichs CS, Restifo NP. Reassessing target antigens for adoptive T-cell therapy. Nat Biotechnol. 2013;31:999-1008.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 999-1008
-
-
Hinrichs, C.S.1
Restifo, N.P.2
-
25
-
-
33646440024
-
Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
-
Lamers CH, Sleijfer S, Vulto AG, et al. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol. 2006;24:e20-e22.
-
(2006)
J Clin Oncol.
, vol.24
-
-
Lamers, C.H.1
Sleijfer, S.2
Vulto, A.G.3
-
26
-
-
84878605813
-
Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: Clinical evaluation and management of on-target toxicity
-
Lamers CH, Sleijfer S, van SS, et al. Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity. Mol Ther. 2013;21:904-912.
-
(2013)
Mol Ther.
, vol.21
, pp. 904-912
-
-
Lamers, C.H.1
Sleijfer, S.2
Van, S.S.3
-
27
-
-
33947265424
-
Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
-
Park JR, Digiusto DL, Slovak M, et al. Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma. Mol Ther. 2007;15:825-833.
-
(2007)
Mol Ther.
, vol.15
, pp. 825-833
-
-
Park, J.R.1
Digiusto, D.L.2
Slovak, M.3
-
28
-
-
33750699642
-
A phase i study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
-
Kershaw MH, Westwood JA, Parker LL, et al. A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin Cancer Res. 2006;12:6106-6115.
-
(2006)
Clin Cancer Res.
, vol.12
, pp. 6106-6115
-
-
Kershaw, M.H.1
Westwood, J.A.2
Parker, L.L.3
-
29
-
-
77958063691
-
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b
-
Craddock JA, Lu A, Bear A, et al. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother. 2010;33:780-788.
-
(2010)
J Immunother
, vol.33
, pp. 780-788
-
-
Craddock, J.A.1
Lu, A.2
Bear, A.3
-
30
-
-
0036428790
-
Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2
-
Kershaw MH, Wang G, Westwood JA, et al. Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. Hum Gene Ther. 2002;13:1971-1980.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1971-1980
-
-
Kershaw, M.H.1
Wang, G.2
Westwood, J.A.3
-
31
-
-
55549145071
-
Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
-
Pule MA, Savoldo B, Myers GD, et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med. 2008;14:1264-1270.
-
(2008)
Nat Med.
, vol.14
, pp. 1264-1270
-
-
Pule, M.A.1
Savoldo, B.2
Myers, G.D.3
-
32
-
-
82955207691
-
Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
-
Louis CU, Savoldo B, Dotti G, et al. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood. 2011;118:6050-6056.
-
(2011)
Blood
, vol.118
, pp. 6050-6056
-
-
Louis, C.U.1
Savoldo, B.2
Dotti, G.3
-
33
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
Morgan RA, Yang JC, Kitano M, et al. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther. 2010;18:843-851.
-
(2010)
Mol Ther
, vol.18
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
-
34
-
-
84890246911
-
T cells redirected against HER2 for the adoptive immunotherapy for HER2-positive osteosarcoma
-
Abstract
-
Ahmed N, Brawley V, Diouf O, et al. T cells redirected against HER2 for the adoptive immunotherapy for HER2-positive osteosarcoma. Cancer Res. 2012;72: Abstract.
-
(2012)
Cancer Res.
, pp. 72
-
-
Ahmed, N.1
Brawley, V.2
Diouf, O.3
-
35
-
-
33748749338
-
Immune resistance orchestrated by the tumor microenvironment
-
Gajewski TF, Meng Y, Blank C, et al. Immune resistance orchestrated by the tumor microenvironment. Immunol Rev. 2006;213:131-145.
-
(2006)
Immunol Rev
, vol.213
, pp. 131-145
-
-
Gajewski, T.F.1
Meng, Y.2
Blank, C.3
-
36
-
-
35549007239
-
Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes
-
Quintarelli C, Vera JF, Savoldo B, et al. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood. 2007;110:2793-2802.
-
(2007)
Blood.
, vol.110
, pp. 2793-2802
-
-
Quintarelli, C.1
Vera, J.F.2
Savoldo, B.3
-
37
-
-
77954590000
-
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their antilymphoma/ leukemia effects and safety
-
Hoyos V, Savoldo B, Quintarelli C, et al. Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their antilymphoma/ leukemia effects and safety. Leukemia. 2010;24:1160-1170.
-
(2010)
Leukemia.
, vol.24
, pp. 1160-1170
-
-
Hoyos, V.1
Savoldo, B.2
Quintarelli, C.3
-
38
-
-
84871939748
-
Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: Implications for adoptive T cell-based therapies for lymphoma
-
Perna SK, De AB, Pagliara D, et al. Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma. Clin Cancer Res. 2013;19:106-117.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 106-117
-
-
De Perna, S.K.A.B.1
Pagliara, D.2
-
39
-
-
84879696103
-
Collapse of the tumor stroma is triggered by IL-12 induction of Fas
-
Kerkar SP, Leonardi AJ, van PN, et al. Collapse of the tumor stroma is triggered by IL-12 induction of Fas. Mol Ther. 2013;21:1369-1377.
-
(2013)
Mol Ther.
, vol.21
, pp. 1369-1377
-
-
Kerkar, S.P.1
Leonardi, A.J.2
Van, P.N.3
-
40
-
-
79953325686
-
Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment
-
Zhang L, Kerkar SP, Yu Z, et al. Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment. Mol Ther. 2011;19:751-759.
-
(2011)
Mol Ther.
, vol.19
, pp. 751-759
-
-
Zhang, L.1
Kerkar, S.P.2
Yu, Z.3
-
41
-
-
77953023274
-
TGF-beta and immune cells: An important regulatory axis in the tumor microenvironment and progression
-
Yang L, Pang Y, Moses HL. TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. Trends Immunol. 2010;31:220-227.
-
(2010)
Trends Immunol
, vol.31
, pp. 220-227
-
-
Yang, L.1
Pang, Y.2
Moses, H.L.3
-
42
-
-
0036566184
-
Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
-
Bollard CM, Rossig C, Calonge MJ, et al. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood. 2002;99:3179-3187.
-
(2002)
Blood
, vol.99
, pp. 3179-3187
-
-
Bollard, C.M.1
Rossig, C.2
Calonge, M.J.3
-
43
-
-
55249117972
-
Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor
-
Foster AE, Dotti G, Lu A, et al. Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor. J Immunother. 2008;31:500-505.
-
(2008)
J Immunother
, vol.31
, pp. 500-505
-
-
Foster, A.E.1
Dotti, G.2
Lu, A.3
-
44
-
-
84885470877
-
Administration of TGF-beta resistant tumor-specific CTL to patienst with EBV-associated HL and NHL
-
Bollard CM, Dotti G, Gottschalk S, et al. Administration of TGF-beta resistant tumor-specific CTL to patienst with EBV-associated HL and NHL. Mol Ther. 2012;20:S22.
-
(2012)
Mol Ther.
, vol.20
-
-
Bollard, C.M.1
Dotti, G.2
Gottschalk, S.3
-
45
-
-
77955503406
-
Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4
-
Wilkie S, Burbridge SE, Chiapero-Stanke L, et al. Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4. J Biol Chem. 2010;285:25538-25544.
-
(2010)
J Biol Chem
, vol.285
, pp. 25538-25544
-
-
Wilkie, S.1
Burbridge, S.E.2
Chiapero-Stanke, L.3
-
46
-
-
84890244501
-
Improved expansion and anti-tumor activity of tumor-specific CTLs using a transgenic chimeric cytokine receptor
-
Leen A, Katari U, Keiman J, et al. Improved expansion and anti-tumor activity of tumor-specific CTLs using a transgenic chimeric cytokine receptor. Mol Ther. 2011;19:S194.
-
(2011)
Mol Ther.
, vol.19
-
-
Leen, A.1
Katari, U.2
Keiman, J.3
-
47
-
-
84890221921
-
Transgenic expression of a novel immunosuppressive signal converter on T cells
-
Watanabe N, Anurathapan U, Brenner M, et al. Transgenic expression of a novel immunosuppressive signal converter on T cells. Mol Ther. 2013;22:S153.
-
(2013)
Mol Ther.
, vol.22
-
-
Watanabe, N.1
Anurathapan, U.2
Brenner, M.3
-
48
-
-
84885461249
-
Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity
-
Ankri C, Shamalov K, Horovitz-Fried M, et al. Human T cells engineered to express a programmed death 1/28 costimulatory retargeting molecule display enhanced antitumor activity. J Immunol. 2013;191:4121-4129.
-
(2013)
J Immunol.
, vol.191
, pp. 4121-4129
-
-
Ankri, C.1
Shamalov, K.2
Horovitz-Fried, M.3
-
49
-
-
20444425695
-
Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis
-
Dotti G, Savoldo B, Pule M, et al. Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. Blood. 2005;105:4677-4684.
-
(2005)
Blood.
, vol.105
, pp. 4677-4684
-
-
Dotti, G.1
Savoldo, B.2
Pule, M.3
-
50
-
-
78049468066
-
T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms
-
Sun J, Dotti G, Huye LE, et al. T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms. Mol Ther. 2010;18:2006-2017.
-
(2010)
Mol Ther.
, vol.18
, pp. 2006-2017
-
-
Sun, J.1
Dotti, G.2
Huye, L.E.3
-
52
-
-
84881312673
-
Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma
-
Kakarla S, Chow KK, Mata M, et al. Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma. Mol Ther. 2013;8:1611-1620.
-
(2013)
Mol Ther
, vol.8
, pp. 1611-1620
-
-
Kakarla, S.1
Chow, K.K.2
Mata, M.3
-
53
-
-
84880656055
-
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
-
Tran E, Chinnasamy D, Yu Z, et al. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J Exp Med. 2013;210:1125-1135.
-
(2013)
J Exp Med
, vol.210
, pp. 1125-1135
-
-
Tran, E.1
Chinnasamy, D.2
Yu, Z.3
-
54
-
-
84880687861
-
Depletion of stromal cells expressing fibroblast activation protein-alpha from skeletal muscle and bone marrow results in cachexia and anemia
-
Roberts EW, Deonarine A, Jones JO, et al. Depletion of stromal cells expressing fibroblast activation protein-alpha from skeletal muscle and bone marrow results in cachexia and anemia. J Exp Med. 2013;210:1137-1151.
-
(2013)
J Exp Med
, vol.210
, pp. 1137-1151
-
-
Roberts, E.W.1
Deonarine, A.2
Jones, J.O.3
-
55
-
-
0037076297
-
Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors
-
Niederman TM, Ghogawala Z, Carter BS, et al. Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors. Proc Natl Acad Sci U S A. 2002;99:7009-7014.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7009-7014
-
-
Niederman, T.M.1
Ghogawala, Z.2
Carter, B.S.3
-
56
-
-
78049436238
-
Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice
-
Chinnasamy D, Yu Z, Theoret MR, et al. Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice. J Clin Invest. 2010;120:3953-3968.
-
(2010)
J Clin Invest
, vol.120
, pp. 3953-3968
-
-
Chinnasamy, D.1
Yu, Z.2
Theoret, M.R.3
-
57
-
-
66849135251
-
Cancer immunotherapy: Co-stimulatory agonists and co-inhibitory antagonists
-
Peggs KS, Quezada SA, Allison JP. Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists. Clin Exp Immunol. 2009;157:9-19.
-
(2009)
Clin Exp Immunol
, vol.157
, pp. 9-19
-
-
Peggs, K.S.1
Quezada, S.A.2
Allison, J.P.3
-
58
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010;363:711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
59
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL,Hodi FS,Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
60
-
-
84862882003
-
Tumor immunotherapy directed at PD-1
-
Ribas A. Tumor immunotherapy directed at PD-1. N Engl J Med. 2012;366:2517-2519.
-
(2012)
N Engl J Med
, vol.366
, pp. 2517-2519
-
-
Ribas, A.1
-
61
-
-
84863138984
-
Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer
-
Chou J, Voong LN, Mortales CL, et al. Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer. J Immunother. 2012;35:131-141.
-
(2012)
J Immunother
, vol.35
, pp. 131-141
-
-
Chou, J.1
Voong, L.N.2
Mortales, C.L.3
-
62
-
-
84872514398
-
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice
-
Liu C, PengW, Xu C, et al. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res. 2013;19:393-403.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 393-403
-
-
Liu, C.1
Peng, W.2
Xu, C.3
-
63
-
-
79955517235
-
CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
-
Savoldo B, Ramos CA, Liu E, et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest. 2011;121:1822-1826.
-
(2011)
J Clin Invest
, vol.121
, pp. 1822-1826
-
-
Savoldo, B.1
Ramos, C.A.2
Liu, E.3
|