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Volumn 81, Issue , 2017, Pages 92-101

Lipopolysaccharides-stimulated macrophage products enhance Withaferin A-induced apoptosis via activation of caspases and inhibition of NF-κB pathway in human cancer cells

Author keywords

Apoptosis; Macrophage; NF B pathway; Withaferin A

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CELL EXTRACT; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; LIPOPOLYSACCHARIDE STIMULATED MACROPHAGE PRODUCT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; WITHAFERIN A; X LINKED INHIBITOR OF APOPTOSIS; CONDITIONED MEDIUM; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; WITHANOLIDE;

EID: 85010223582     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2016.10.010     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 0032788630 scopus 로고    scopus 로고
    • Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation
    • Agarwal, R., Diwanay, S., Patki, P., Patwardhan, B., Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. J. Ethnopharmacol. 67:1 (1999), 27–35.
    • (1999) J. Ethnopharmacol. , vol.67 , Issue.1 , pp. 27-35
    • Agarwal, R.1    Diwanay, S.2    Patki, P.3    Patwardhan, B.4
  • 2
    • 18044398197 scopus 로고    scopus 로고
    • Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats
    • Ahmad, M., Saleem, S., Ahmad, A.S., Ansari, M.A., Yousuf, S., Hoda, M.N., Islam, F., Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats. Hum. Exp. Toxicol. 24:3 (2005), 137–147.
    • (2005) Hum. Exp. Toxicol. , vol.24 , Issue.3 , pp. 137-147
    • Ahmad, M.1    Saleem, S.2    Ahmad, A.S.3    Ansari, M.A.4    Yousuf, S.5    Hoda, M.N.6    Islam, F.7
  • 3
    • 84960128329 scopus 로고    scopus 로고
    • Tumor-associated macrophages and anti-tumor therapies: complex links
    • Belgiovine, C., D'Incalci, M., Allavena, P., Frapolli, R., Tumor-associated macrophages and anti-tumor therapies: complex links. Cell. Mol. Life Sci. 73:13 (2016), 2411–2424.
    • (2016) Cell. Mol. Life Sci. , vol.73 , Issue.13 , pp. 2411-2424
    • Belgiovine, C.1    D'Incalci, M.2    Allavena, P.3    Frapolli, R.4
  • 4
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
    • Biswas, S.K., Mantovani, A., Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 11:10 (2010), 889–896.
    • (2010) Nat. Immunol. , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 5
    • 84920943285 scopus 로고    scopus 로고
    • Tumor-associated macrophages as major players in the tumor microenvironment
    • Chanmee, T., Ontong, P., Konno, K., Itano, N., Tumor-associated macrophages as major players in the tumor microenvironment. Cancers 6:3 (2014), 1670–1690.
    • (2014) Cancers , vol.6 , Issue.3 , pp. 1670-1690
    • Chanmee, T.1    Ontong, P.2    Konno, K.3    Itano, N.4
  • 6
    • 77954687601 scopus 로고    scopus 로고
    • Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment
    • Clear, A.J., Lee, A.M., Calaminici, M., Ramsay, A.G., Morris, K.J., Hallam, S., Kelly, G., Macdougall, F., Lister, T.A., Gribben, J.G., Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment. Blood 115:24 (2010), 5053–5056.
    • (2010) Blood , vol.115 , Issue.24 , pp. 5053-5056
    • Clear, A.J.1    Lee, A.M.2    Calaminici, M.3    Ramsay, A.G.4    Morris, K.J.5    Hallam, S.6    Kelly, G.7    Macdougall, F.8    Lister, T.A.9    Gribben, J.G.10
  • 7
    • 84876424760 scopus 로고    scopus 로고
    • Macrophage regulation of tumor responses to anticancer therapies
    • De Palma, M., Lewis, C.E., Macrophage regulation of tumor responses to anticancer therapies. Cancer Cell 23:3 (2013), 277–286.
    • (2013) Cancer Cell , vol.23 , Issue.3 , pp. 277-286
    • De Palma, M.1    Lewis, C.E.2
  • 8
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins–suppressors of apoptosis
    • Deveraux, Q.L., Reed, J.C., IAP family proteins–suppressors of apoptosis. Genes Dev. 13:3 (1999), 239–252.
    • (1999) Genes Dev. , vol.13 , Issue.3 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 9
    • 84896490235 scopus 로고    scopus 로고
    • The two faces of IL-6 in the tumor microenvironment
    • Fisher, D.T., Appenheimer, M.M., Evans, S.S., The two faces of IL-6 in the tumor microenvironment. Semin. Immunol. 26:1 (2014), 38–47.
    • (2014) Semin. Immunol. , vol.26 , Issue.1 , pp. 38-47
    • Fisher, D.T.1    Appenheimer, M.M.2    Evans, S.S.3
  • 10
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: mechanism and functions
    • Gordon, S., Martinez, F.O., Alternative activation of macrophages: mechanism and functions. Immunity 32:5 (2010), 593–604.
    • (2010) Immunity , vol.32 , Issue.5 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 11
    • 65349089029 scopus 로고    scopus 로고
    • Regulation of XIAP translation and induction by MDM2 following irradiation
    • Gu, L., Zhu, N., Zhang, H., Durden, D.L., Feng, Y., Zhou, M., Regulation of XIAP translation and induction by MDM2 following irradiation. Cancer Cell 15:5 (2009), 363–375.
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 363-375
    • Gu, L.1    Zhu, N.2    Zhang, H.3    Durden, D.L.4    Feng, Y.5    Zhou, M.6
  • 12
    • 4344577070 scopus 로고    scopus 로고
    • Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment
    • Gupta, S.K., Mohanty, I., Talwar, K.K., Dinda, A., Joshi, S., Bansal, P., Saxena, A., Arya, D.S., Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment. Mol. Cell. Biochem. 260:1–2 (2004), 39–47.
    • (2004) Mol. Cell. Biochem. , vol.260 , Issue.1-2 , pp. 39-47
    • Gupta, S.K.1    Mohanty, I.2    Talwar, K.K.3    Dinda, A.4    Joshi, S.5    Bansal, P.6    Saxena, A.7    Arya, D.S.8
  • 13
    • 0015820560 scopus 로고
    • Selective cytotoxicity of peritoneal leucocytes for neoplastic cells
    • Holtermann, O.A., Klein, E., Casale, G.P., Selective cytotoxicity of peritoneal leucocytes for neoplastic cells. Cell. Immunol. 9:3 (1973), 339–352.
    • (1973) Cell. Immunol. , vol.9 , Issue.3 , pp. 339-352
    • Holtermann, O.A.1    Klein, E.2    Casale, G.P.3
  • 14
  • 17
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • Karin, M., Cao, Y., Greten, F.R., Li, Z.W., NF-kappaB in cancer: from innocent bystander to major culprit. Nat. Rev. Cancer 2:4 (2002), 301–310.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 18
    • 84940213996 scopus 로고    scopus 로고
    • Expression of CD 68, CD 45 and human leukocyte antigen-DR in central and peripheral giant cell granuloma, giant cell tumor of long bones, and tuberculous granuloma: an immunohistochemical study
    • Kumar, A., Sherlin, H.J., Ramani, P., Natesan, A., Premkumar, P., Expression of CD 68, CD 45 and human leukocyte antigen-DR in central and peripheral giant cell granuloma, giant cell tumor of long bones, and tuberculous granuloma: an immunohistochemical study. Indian J. Dent. Res. 26:3 (2015), 295–303.
    • (2015) Indian J. Dent. Res. , vol.26 , Issue.3 , pp. 295-303
    • Kumar, A.1    Sherlin, H.J.2    Ramani, P.3    Natesan, A.4    Premkumar, P.5
  • 19
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) and their emerging role in cancer
    • LaCasse, E.C., Baird, S., Korneluk, R.G., MacKenzie, A.E., The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17:25 (1998), 3247–3259.
    • (1998) Oncogene , vol.17 , Issue.25 , pp. 3247-3259
    • LaCasse, E.C.1    Baird, S.2    Korneluk, R.G.3    MacKenzie, A.E.4
  • 20
    • 84861747433 scopus 로고    scopus 로고
    • Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models
    • Lee, W., Kim, T.H., Ku, S.K., Min, K.J., Lee, H.S., Kwon, T.K., Bae, J.S., Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models. Toxicol. Appl. Pharmacol. 262:1 (2012), 91–98.
    • (2012) Toxicol. Appl. Pharmacol. , vol.262 , Issue.1 , pp. 91-98
    • Lee, W.1    Kim, T.H.2    Ku, S.K.3    Min, K.J.4    Lee, H.S.5    Kwon, T.K.6    Bae, J.S.7
  • 21
    • 84979782465 scopus 로고    scopus 로고
    • The multifaceted role of perivascular macrophages in tumors
    • Lewis, C.E., Harney, A.S., Pollard, J.W., The multifaceted role of perivascular macrophages in tumors. Cancer Cell 30:1 (2016), 18–25.
    • (2016) Cancer Cell , vol.30 , Issue.1 , pp. 18-25
    • Lewis, C.E.1    Harney, A.S.2    Pollard, J.W.3
  • 22
    • 84920496306 scopus 로고    scopus 로고
    • Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3 K/AKT pathway in human pancreatic cancer cells
    • Li, X., Zhu, F., Jiang, J., Sun, C., Wang, X., Shen, M., Tian, R., Shi, C., Xu, M., Peng, F., Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3 K/AKT pathway in human pancreatic cancer cells. Cancer Lett. 357:1 (2015), 219–230.
    • (2015) Cancer Lett. , vol.357 , Issue.1 , pp. 219-230
    • Li, X.1    Zhu, F.2    Jiang, J.3    Sun, C.4    Wang, X.5    Shen, M.6    Tian, R.7    Shi, C.8    Xu, M.9    Peng, F.10
  • 23
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin, W.W., Karin, M., A cytokine-mediated link between innate immunity, inflammation, and cancer. J. Clin. Invest. 117:5 (2007), 1175–1183.
    • (2007) J. Clin. Invest. , vol.117 , Issue.5 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 24
    • 79851474637 scopus 로고    scopus 로고
    • Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant ‘thunder god vine'
    • Lu, L., Kanwar, J., Schmitt, S., Cui, Q.C., Zhang, C., Zhao, C., Dou, Q.P., Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant ‘thunder god vine'. Anticancer Res. 31:1 (2011), 1–10.
    • (2011) Anticancer Res. , vol.31 , Issue.1 , pp. 1-10
    • Lu, L.1    Kanwar, J.2    Schmitt, S.3    Cui, Q.C.4    Zhang, C.5    Zhao, C.6    Dou, Q.P.7
  • 25
    • 84912573923 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis
    • Lu, L., Shi, W., Deshmukh, R.R., Long, J., Cheng, X., Ji, W., Zeng, G., Chen, X., Zhang, Y., Dou, Q.P., Tumor necrosis factor-alpha sensitizes breast cancer cells to natural products with proteasome-inhibitory activity leading to apoptosis. PLoS One, 9(11), 2014, e113783.
    • (2014) PLoS One , vol.9 , Issue.11 , pp. e113783
    • Lu, L.1    Shi, W.2    Deshmukh, R.R.3    Long, J.4    Cheng, X.5    Ji, W.6    Zeng, G.7    Chen, X.8    Zhang, Y.9    Dou, Q.P.10
  • 26
    • 77957876452 scopus 로고    scopus 로고
    • Mycobacterium bovis bacillus Calmette-Guerin-induced macrophage cytotoxicity against bladder cancer cells
    • Luo, Y., Knudson, M.J., Mycobacterium bovis bacillus Calmette-Guerin-induced macrophage cytotoxicity against bladder cancer cells. Clin. Dev. Immunol., 2010, 2010, 357591.
    • (2010) Clin. Dev. Immunol. , vol.2010 , pp. 357591
    • Luo, Y.1    Knudson, M.J.2
  • 27
    • 56349141560 scopus 로고    scopus 로고
    • Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade
    • Mandal, C., Dutta, A., Mallick, A., Chandra, S., Misra, L., Sangwan, R.S., Mandal, C., Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade. Apoptosis: Int. J. Program. Cell Death 13:12 (2008), 1450–1464.
    • (2008) Apoptosis: Int. J. Program. Cell Death , vol.13 , Issue.12 , pp. 1450-1464
    • Mandal, C.1    Dutta, A.2    Mallick, A.3    Chandra, S.4    Misra, L.5    Sangwan, R.S.6    Mandal, C.7
  • 28
    • 84928226005 scopus 로고    scopus 로고
    • The interaction of anticancer therapies with tumor-associated macrophages
    • Mantovani, A., Allavena, P., The interaction of anticancer therapies with tumor-associated macrophages. J. Exp. Med. 212:4 (2015), 435–445.
    • (2015) J. Exp. Med. , vol.212 , Issue.4 , pp. 435-445
    • Mantovani, A.1    Allavena, P.2
  • 29
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani, A., Sica, A., Sozzani, S., Allavena, P., Vecchi, A., Locati, M., The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25:12 (2004), 677–686.
    • (2004) Trends Immunol. , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 30
  • 31
    • 0018170299 scopus 로고
    • Tumour-necrosis factor from the rabbit I. Mode of action, specificity and physicochemical properties
    • Matthews, N., Watkins, J.F., Tumour-necrosis factor from the rabbit I. Mode of action, specificity and physicochemical properties. Br. J. Cancer 38:2 (1978), 302–309.
    • (1978) Br. J. Cancer , vol.38 , Issue.2 , pp. 302-309
    • Matthews, N.1    Watkins, J.F.2
  • 33
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D.M., Edwards, J.P., Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8:12 (2008), 958–969.
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 34
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray, P.J., Wynn, T.A., Protective and pathogenic functions of macrophage subsets. Nat. Rev. Immunol. 11:11 (2011), 723–737.
    • (2011) Nat. Rev. Immunol. , vol.11 , Issue.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 36
    • 55849103960 scopus 로고    scopus 로고
    • Macrophage diversity in renal injury and repair
    • Ricardo, S.D., van Goor, H., Eddy, A.A., Macrophage diversity in renal injury and repair. J. Clin. Invest. 118:11 (2008), 3522–3530.
    • (2008) J. Clin. Invest. , vol.118 , Issue.11 , pp. 3522-3530
    • Ricardo, S.D.1    van Goor, H.2    Eddy, A.A.3
  • 38
    • 36849017497 scopus 로고    scopus 로고
    • IL-6 involvement in epithelial cancers
    • Schafer, Z.T., Brugge, J.S., IL-6 involvement in epithelial cancers. J. Clin. Invest. 117:12 (2007), 3660–3663.
    • (2007) J. Clin. Invest. , vol.117 , Issue.12 , pp. 3660-3663
    • Schafer, Z.T.1    Brugge, J.S.2
  • 41
    • 84965127146 scopus 로고    scopus 로고
    • The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases
    • Tan, H.Y., Wang, N., Li, S., Hong, M., Wang, X., Feng, Y., The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases. Oxid. Med. Cell. Longevity, 2016, 2016, 2795090.
    • (2016) Oxid. Med. Cell. Longevity , vol.2016 , pp. 2795090
    • Tan, H.Y.1    Wang, N.2    Li, S.3    Hong, M.4    Wang, X.5    Feng, Y.6
  • 43
    • 58149185984 scopus 로고    scopus 로고
    • L-Glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells
    • Xiao, Y., Bi, C., Fan, Y., Cui, C., Zhang, X., Dou, Q.P., L-Glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells. Int. J. Oncol. 33:5 (2008), 1073–1079.
    • (2008) Int. J. Oncol. , vol.33 , Issue.5 , pp. 1073-1079
    • Xiao, Y.1    Bi, C.2    Fan, Y.3    Cui, C.4    Zhang, X.5    Dou, Q.P.6
  • 44
    • 33846454701 scopus 로고    scopus 로고
    • The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from Indian winter cherry
    • Yang, H., Shi, G., Dou, Q.P., The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from Indian winter cherry. Mol. Pharmacol. 71:2 (2007), 426–437.
    • (2007) Mol. Pharmacol. , vol.71 , Issue.2 , pp. 426-437
    • Yang, H.1    Shi, G.2    Dou, Q.P.3
  • 45
    • 58849167699 scopus 로고    scopus 로고
    • The isolation and characterization of murine macrophages
    • edited by John E Coligan [et al], Chapter 14:Unit 14
    • Zhang, X., Goncalves, R., Mosser, D.M., The isolation and characterization of murine macrophages. Curr. Adv. Immunol., 11, 2008 edited by John E Coligan [et al], Chapter 14:Unit 14.
    • (2008) Curr. Adv. Immunol. , vol.11
    • Zhang, X.1    Goncalves, R.2    Mosser, D.M.3


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