Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Molecular Neurodegeneration

Volumn 12, Issue 1, 2017, Pages 1-11

  Ohki, Yu ^a,b   Wenninger Weinzierl, Andrea ^a   Hruscha, Alexander ^a   Asakawa, Kazuhide ^c   Kawakami, Koichi ^c   Haass, Christian ^a,b,d   Edbauer, Dieter ^a,d   Schmid, Bettina ^a,d  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c NATIONAL INSTITUTE OF GENETICS   (Japan)

^d Germany 3 Munich Cluster for Systems Neurology   (Germany)

Author keywords

C9orf72; poly GA toxicity; Zebrafish

Indexed keywords

DIPEPTIDE; GLYCYLALANINE; GREEN FLUORESCENT PROTEIN; MORPHOLINO OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; PEPTIDE; POLY(ALANYLGLYCINE);

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CHROMOSOME 9; CONTROLLED STUDY; EMBRYO; GENETIC TRANSCRIPTION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; OPEN READING FRAME; PROTEIN PROCESSING; START CODON; ZEBRA FISH; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; DINUCLEOTIDE REPEAT; DISEASE MODEL; FLUORESCENCE IN SITU HYBRIDIZATION; FRONTOTEMPORAL DEMENTIA; GENETICS; IMMUNOHISTOCHEMISTRY; PATHOLOGY; POLYMERASE CHAIN REACTION; TRANSGENIC ANIMAL; WESTERN BLOTTING;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOTTING, WESTERN; DINUCLEOTIDE REPEATS; DISEASE MODELS, ANIMAL; FRONTOTEMPORAL LOBAR DEGENERATION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; OPEN READING FRAMES; PEPTIDES; POLYMERASE CHAIN REACTION; ZEBRAFISH;

EID: 85009354554     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-016-0146-8     Document Type: Article

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