C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD

Neuron

Volumn 88, Issue 5, 2015, Pages 892-901

  O'Rourke, Jacqueline G ^a   Bogdanik, Laurent ^b   Muhammad, A K M G ^a   Gendron, Tania F ^c   Kim, Kevin J ^a   Austin, Andrew ^b   Cady, Janet ^d   Liu, Elaine Y ^e   Zarrow, Jonah ^a   Grant, Sharday ^a   Ho, Ritchie ^a   Bell, Shaughn ^a   Carmona, Sharon ^a   Simpkinson, Megan ^a   Lall, Deepti ^a   Wu, Kathryn ^a   Daughrity, Lillian ^c   Dickson, Dennis W ^c   Harms, Matthew B ^d   Petrucelli, Leonard ^c   Lee, Edward B ^e   Lutz, Cathleen M ^b   Baloh, Robert H ^a   more..

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b JACKSON LABORATORY   (United States)

^c MAYO GRADUATE SCHOOL   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DIPEPTIDE; NUCLEOLIN; REPEAT ASSOCIATED NON ATG TRANSLATED DIPEPTIDE; RNA; UNCLASSIFIED DRUG; C9ORF72 PROTEIN, HUMAN; GLUTAMIC ACID; PROTEIN; REPETITIVE DNA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BEHAVIOR DISORDER; C9ORF72 GENE; CELLULAR PARAMETERS; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPATHOLOGY; DNA STRUCTURE; FRONTOTEMPORAL DEMENTIA; GENE TARGETING; GENETIC ASSOCIATION; HEXANUCLEOTIDE REPEAT; MALE; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; NUCLEOLAR DYSFUNCTION; NUCLEOLAR STRESS; OPEN READING FRAME; PRIORITY JOURNAL; SKIN FIBROBLAST; TRANSGENIC MOUSE; AGE; ANIMAL; BRAIN; CELL CULTURE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOTOR ACTIVITY; MUSCLE STRENGTH; NERVE CELL; NEUROMUSCULAR JUNCTION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SPINAL CORD;

AGE FACTORS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DISEASE MODELS, ANIMAL; DNA REPEAT EXPANSION; FRONTOTEMPORAL DEMENTIA; GLUTAMIC ACID; HUMANS; MICE; MICE, TRANSGENIC; MOTOR ACTIVITY; MUSCLE STRENGTH; NEUROMUSCULAR JUNCTION; NEURONS; PROTEINS; PSYCHOMOTOR PERFORMANCE; SPINAL CORD;

EID: 84949422392     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.10.027     Document Type: Article

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