Aging exacerbates acute lung injury-induced changes of the air-blood barrier, lung function, and inflammation in the mouse

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 312, Issue 1, 2017, Pages L1-L12

  Kling, Katharina Maria ^a,b   Lopez Rodriguez, Elena ^a,b   Pfarrer, Christiane ^c   Mühlfeld, Christian ^a,b,d   Brandenberger, Christina ^a,b,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Member of the German Center for Lung Research   (Germany)

^c UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^d Cluster of Excellence REBIRTH (From Regenerative Biology to Reconstructive Therapy)   (Germany)

Author keywords

Acute lung injury; Aging; Air blood barrier; Lung function; Neutrophilic inflammation

Indexed keywords

CXCL1 CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; METALLOPROTEINASE; OCCLUDIN; COLLAGEN; ELASTIN;

ACUTE LUNG INJURY; AGE; AGING; AIR BLOOD BARRIER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CONTROLLED STUDY; CYTOMETRY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HISTOPATHOLOGY; LUNG COMPLIANCE; LUNG FUNCTION; LUNG PARENCHYMA; LUNG STRUCTURE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PERMEABILITY BARRIER; PNEUMONIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STEREOLOGY; ANIMAL; C57BL MOUSE; COMPLICATION; CYTOLOGY; DISEASE EXACERBATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; LUNG; LUNG ALVEOLUS; LUNG FUNCTION TEST; LUNG GAS EXCHANGE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; ULTRASTRUCTURE;

ACUTE LUNG INJURY; AGING; ANIMALS; BLOOD-AIR BARRIER; BODY WEIGHT; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; COLLAGEN; DISEASE PROGRESSION; ELASTIN; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE, INBRED C57BL; PNEUMONIA; PULMONARY ALVEOLI; RESPIRATORY FUNCTION TESTS;

EID: 85008411775     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00347.2016     Document Type: Article

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