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Volumn 9, Issue 9, 2013, Pages 966-979

Interleukin-8 regulates endothelial permeability by down-regulation of tight junction but not dependent on integrins induced focal adhesions

Author keywords

Claudin 5; Endothelial permeability; Il 8; Occludin; Tight junction; Zo 1

Indexed keywords

CLAUDIN 5; INTEGRIN; INTERLEUKIN 8; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1; TJP1 PROTEIN, HUMAN;

EID: 84884561289     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.6996     Document Type: Article
Times cited : (116)

References (50)
  • 1
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev. 2006; 86: 279-367.
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 2
    • 0037372379 scopus 로고    scopus 로고
    • Protein kinase C modulates pulmonary endothelial permeability: A paradigm for acute lung injury
    • Siflinger-Birnboim A, Johnson A. Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2003; 284: L435-451.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284
    • Siflinger-Birnboim, A.1    Johnson, A.2
  • 3
    • 4143067127 scopus 로고    scopus 로고
    • Ablation of peripheral dopaminergic nerves stimulates malignant tumor growth by inducing vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis
    • Basu S, Sarkar C, Chakroborty D, Nagy J, Mitra RB, Dasgupta PS, Mukhopadhyay D. Ablation of peripheral dopaminergic nerves stimulates malignant tumor growth by inducing vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis. Cancer Res. 2004; 64: 5551-5555.
    • (2004) Cancer Res , vol.64 , pp. 5551-5555
    • Basu, S.1    Sarkar, C.2    Chakroborty, D.3    Nagy, J.4    Mitra, R.B.5    Dasgupta, P.S.6    Mukhopadhyay, D.7
  • 4
    • 33646049704 scopus 로고    scopus 로고
    • Brief heat shock affects the permeability and thermotolerance of an in vitro blood-brain barrier model of porcine brain microvascular endothelial cells
    • Jeliazkova-Mecheva VV, Hymer WC, Nicholas NC, Bobilya DJ. Brief heat shock affects the permeability and thermotolerance of an in vitro blood-brain barrier model of porcine brain microvascular endothelial cells. Microvasc Res. 2006; 71: 108-114.
    • (2006) Microvasc Res , vol.71 , pp. 108-114
    • Jeliazkova-Mecheva, V.V.1    Hymer, W.C.2    Nicholas, N.C.3    Bobilya, D.J.4
  • 5
    • 33646794056 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability
    • Pickkers P, Sprong T, Eijk L, Hoeven H, Smits P, Deuren M. Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability. Shock. 2005; 24: 508-512.
    • (2005) Shock , vol.24 , pp. 508-512
    • Pickkers, P.1    Sprong, T.2    Eijk, L.3    Hoeven, H.4    Smits, P.5    Deuren, M.6
  • 6
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation. 2004; 109(23 Suppl 1): III27-32.
    • (2004) Circulation , vol.109 , Issue.23 SUPPL. 1
    • Davignon, J.1    Ganz, P.2
  • 7
    • 0031952083 scopus 로고    scopus 로고
    • Tight junctions
    • Balda MS, Matter K. Tight junctions. J Cell Sci 111. 1998; (Pt 5):541-547.
    • (1998) J Cell Sci , vol.111 , Issue.PART 5 , pp. 541-547
    • Balda, M.S.1    Matter, K.2
  • 8
    • 0037336565 scopus 로고    scopus 로고
    • Signalling to and from tight junctions
    • Matter K, Balda MS. Signalling to and from tight junctions. Nat Rev Mol Cell Biol. 2003; 4:225-236.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 225-236
    • Matter, K.1    Balda, M.S.2
  • 9
    • 78049280268 scopus 로고    scopus 로고
    • TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability
    • Aveleira CA, Lin CM, Abcouwer SF, Ambrosio AF, Antonetti DA. TNF-alpha signals through PKCzeta/NF-kappaB to alter the tight junction complex and increase retinal endothelial cell permeability. Diabetes. 2010; 59: 2872-2882.
    • (2010) Diabetes , vol.59 , pp. 2872-2882
    • Aveleira, C.A.1    Lin, C.M.2    Abcouwer, S.F.3    Ambrosio, A.F.4    Antonetti, D.A.5
  • 10
    • 68949129005 scopus 로고    scopus 로고
    • Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability
    • Murakami T, Felinski EA, Antonetti DA. Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability. J Biol Chem. 2009; 284: 21036-21046.
    • (2009) J Biol Chem , vol.284 , pp. 21036-21046
    • Murakami, T.1    Felinski, E.A.2    Antonetti, D.A.3
  • 11
    • 80052400212 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium
    • Suzuki T, Yoshinaga N, Tanabe S. Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium. J Biol Chem. 2011; 286:31263-31271.
    • (2011) J Biol Chem , vol.286 , pp. 31263-31271
    • Suzuki, T.1    Yoshinaga, N.2    Tanabe, S.3
  • 12
    • 0034527594 scopus 로고    scopus 로고
    • Permeability characteristics of human endothelial monolayers seeded on different extracellular matrix proteins
    • Nooteboom A, Hendriks T, Otteholler I, van der Linden CJ. Permeability characteristics of human endothelial monolayers seeded on different extracellular matrix proteins. Mediators Inflamm. 2000; 9:235-241.
    • (2000) Mediators Inflamm , vol.9 , pp. 235-241
    • Nooteboom, A.1    Hendriks, T.2    Otteholler, I.3    van der Linden, C.J.4
  • 15
    • 17844397949 scopus 로고    scopus 로고
    • The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
    • Brat DJ, Bellail AC, Van Meir EG. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro Oncol. 2005; 7: 122-133.
    • (2005) Neuro Oncol , vol.7 , pp. 122-133
    • Brat, D.J.1    Bellail, A.C.2    van Meir, E.G.3
  • 16
    • 77949840400 scopus 로고    scopus 로고
    • Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins alpha5 and beta1
    • Jovanovic M, Stefanoska I, Radojcic L, Vicovac L. Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins alpha5 and beta1. Reproduction. 2010; 139: 789-798.
    • (2010) Reproduction , vol.139 , pp. 789-798
    • Jovanovic, M.1    Stefanoska, I.2    Radojcic, L.3    Vicovac, L.4
  • 17
    • 0034983102 scopus 로고    scopus 로고
    • IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways
    • Schraufstatter IU, Chung J, Burger M. IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways. Am J Physiol Lung Cell Mol Physiol. 2001; 280: L1094-1103.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Schraufstatter, I.U.1    Chung, J.2    Burger, M.3
  • 18
    • 48049113237 scopus 로고    scopus 로고
    • The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques
    • Papadopoulou C, Corrigall V, Taylor PR, Poston RN. The role of the chemokines MCP-1, GRO-alpha, IL-8 and their receptors in the adhesion of monocytic cells to human atherosclerotic plaques. Cytokine. 2008; 43: 181-186.
    • (2008) Cytokine , vol.43 , pp. 181-186
    • Papadopoulou, C.1    Corrigall, V.2    Taylor, P.R.3    Poston, R.N.4
  • 19
    • 37049036163 scopus 로고    scopus 로고
    • Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability
    • Petreaca ML, Yao M, Liu Y, Defea K, Martins-Green M. Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability. Mol Biol Cell. 2007; 18: 5014-5023.
    • (2007) Mol Biol Cell , vol.18 , pp. 5014-5023
    • Petreaca, M.L.1    Yao, M.2    Liu, Y.3    Defea, K.4    Martins-Green, M.5
  • 20
    • 0033609891 scopus 로고    scopus 로고
    • Activated neutrophils induce hyperpermeability and phosphorylation of adherens junction proteins in coronary venular endothelial cells
    • Tinsley JH, Wu MH, Ma W, Taulman AC, Yuan SY. Activated neutrophils induce hyperpermeability and phosphorylation of adherens junction proteins in coronary venular endothelial cells. J Biol Chem. 1999; 274: 24930-24934.
    • (1999) J Biol Chem , vol.274 , pp. 24930-24934
    • Tinsley, J.H.1    Wu, M.H.2    Ma, W.3    Taulman, A.C.4    Yuan, S.Y.5
  • 21
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin mediated adhesion in morphogenesis
    • Gumbiner BM. Regulation of cadherin mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol. 2005; 6(8): 622-634.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.8 , pp. 622-634
    • Gumbiner, B.M.1
  • 24
    • 0037370316 scopus 로고    scopus 로고
    • Interleukins in atherosclerosis: Molecular pathways and therapeutic potential
    • von der Thusen JH, Kuiper J, van Berkel TJ, Biessen EA. Interleukins in atherosclerosis: molecular pathways and therapeutic potential. Pharmacol Rev. 2003; 55: 133-166.
    • (2003) Pharmacol Rev , vol.55 , pp. 133-166
    • von der Thusen, J.H.1    Kuiper, J.2    van Berkel, T.J.3    Biessen, E.A.4
  • 25
    • 79960980219 scopus 로고    scopus 로고
    • Interleukin-8 Induces the Endothelial Cell Migration through the Activation of Phosphoinositide 3-Kinase-Rac1/RhoA Pathway
    • Lai Y, Shen Y, Liu XH, Zhang Y, Zeng Y, Liu YF. Interleukin-8 Induces the Endothelial Cell Migration through the Activation of Phosphoinositide 3-Kinase-Rac1/RhoA Pathway. Int J Biol Sci. 2011; 7: 782-791.
    • (2011) Int J Biol Sci , vol.7 , pp. 782-791
    • Lai, Y.1    Shen, Y.2    Liu, X.H.3    Zhang, Y.4    Zeng, Y.5    Liu, Y.F.6
  • 26
    • 78349310528 scopus 로고    scopus 로고
    • CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration
    • Zeng Y, Sun HR, Yu C, Lai Y, Liu XJ, Wu J, Chen HQ, Liu XH. CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration. Cytokine. 2011; 53: 42-51.
    • (2011) Cytokine , vol.53 , pp. 42-51
    • Zeng, Y.1    Sun, H.R.2    Yu, C.3    Lai, Y.4    Liu, X.J.5    Wu, J.6    Chen, H.Q.7    Liu, X.H.8
  • 27
    • 84860407637 scopus 로고    scopus 로고
    • IL-8 increases integrin expression and cell motility in human chondrosarcoma cells
    • Lee CY, Huang CY, Chen MY, Lin CY, Hsu HC, Tang CH. IL-8 increases integrin expression and cell motility in human chondrosarcoma cells. J Cell Biochem. 2011; 112: 2549-2557.
    • (2011) J Cell Biochem , vol.112 , pp. 2549-2557
    • Lee, C.Y.1    Huang, C.Y.2    Chen, M.Y.3    Lin, C.Y.4    Hsu, H.C.5    Tang, C.H.6
  • 28
    • 84887212399 scopus 로고    scopus 로고
    • The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells
    • Alghisi GC, Ponsonnet L, Ruegg C. The integrin antagonist cilengitide activates alphaVbeta3, disrupts VE-cadherin localization at cell junctions and enhances permeability in endothelial cells. PLoS One. 2009; 4: e4449.
    • (2009) PLoS One , vol.4
    • Alghisi, G.C.1    Ponsonnet, L.2    Ruegg, C.3
  • 32
    • 79960952144 scopus 로고    scopus 로고
    • IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells
    • Fernando RI, Castillo MD, Litzinger M, Hamilton DH, Palena C. IL-8 signaling plays a critical role in the epithelial-mesenchymal transition of human carcinoma cells. Cancer Res.2011;71: 5296-5306.
    • (2011) Cancer Res , vol.71 , pp. 5296-5306
    • Fernando, R.I.1    Castillo, M.D.2    Litzinger, M.3    Hamilton, D.H.4    Palena, C.5
  • 33
    • 80051799359 scopus 로고    scopus 로고
    • Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells
    • Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K, Tsujiwaki M, Murata M, Tanaka S, Sawada N. Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells. Exp Cell Res. 2011; 317: 2288-2298.
    • (2011) Exp Cell Res , vol.317 , pp. 2288-2298
    • Kojima, T.1    Takasawa, A.2    Kyuno, D.3    Ito, T.4    Yamaguchi, H.5    Hirata, K.6    Tsujiwaki, M.7    Murata, M.8    Tanaka, S.9    Sawada, N.10
  • 35
    • 76749084251 scopus 로고    scopus 로고
    • Signal mechanisms of vascular endothelial growth factor and interleukin-8 in ovarian hyperstimulation syndrome: Dopamine targets their common pathways
    • Chen SU, Chou CH, Lin CW, Lee H, Wu JC, Lu HF, Chen CD, Yang YS. Signal mechanisms of vascular endothelial growth factor and interleukin-8 in ovarian hyperstimulation syndrome: dopamine targets their common pathways. Hum Reprod. 2010;25:757-767.
    • (2010) Hum Reprod , vol.25 , pp. 757-767
    • Chen, S.U.1    Chou, C.H.2    Lin, C.W.3    Lee, H.4    Wu, J.C.5    Lu, H.F.6    Chen, C.D.7    Yang, Y.S.8
  • 36
    • 39849109700 scopus 로고    scopus 로고
    • Crosstalk of tight junction components with signaling pathways
    • González-Mariscal L, Tapia R, Chamorro D. Crosstalk of tight junction components with signaling pathways. Biochim Biophys Acta. 2008;1778: 729-756.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 729-756
    • González-Mariscal, L.1    Tapia, R.2    Chamorro, D.3
  • 37
    • 65449117324 scopus 로고    scopus 로고
    • A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability
    • Gavard J, Hou X, Qu Y, Masedunskas A, Martin D, Weigert R, Li X, Gutkind JS. A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability. Mol Cell Biol. 2009;29(9):2469-2480.
    • (2009) Mol Cell Biol , vol.29 , Issue.9 , pp. 2469-2480
    • Gavard, J.1    Hou, X.2    Qu, Y.3    Masedunskas, A.4    Martin, D.5    Weigert, R.6    Li, X.7    Gutkind, J.S.8
  • 38
    • 77954711307 scopus 로고    scopus 로고
    • Amyloid-beta-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation
    • Tai LM, Holloway KA, Male DK, Loughlin AJ, Romero IA. Amyloid-beta-induced occludin down-regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation. J Cell Mol Med. 2010; 14: 1101-1112.
    • (2010) J Cell Mol Med , vol.14 , pp. 1101-1112
    • Tai, L.M.1    Holloway, K.A.2    Male, D.K.3    Loughlin, A.J.4    Romero, I.A.5
  • 39
    • 34948910651 scopus 로고    scopus 로고
    • Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown
    • Nag S, Venugopalan R, Stewart DJ. Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown. Acta Neuropathol. 2007; 114: 459-469.
    • (2007) Acta Neuropathol , vol.114 , pp. 459-469
    • Nag, S.1    Venugopalan, R.2    Stewart, D.J.3
  • 40
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi R, Ye D, Dokladny K, Ma TY. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J Immunol. 2008; 180: 5653-5661.
    • (2008) J Immunol , vol.180 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 41
    • 78149291807 scopus 로고    scopus 로고
    • IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway
    • Al-Sadi R, Ye D, Said HM, Ma TY. IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1 activation of canonical NF-kappaB pathway. Am J Pathol. 2010; 177: 2310-2322.
    • (2010) Am J Pathol , vol.177 , pp. 2310-2322
    • Al-Sadi, R.1    Ye, D.2    Said, H.M.3    Ma, T.Y.4
  • 43
    • 29244442618 scopus 로고    scopus 로고
    • Endothelial focal adhesions and barrier function
    • Wu MH. Endothelial focal adhesions and barrier function. J Physiol. 2005; 569:359-366.
    • (2005) J Physiol , vol.569 , pp. 359-366
    • Wu, M.H.1
  • 46
    • 34848855176 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src
    • Lee YH, Kayyali US, Sousa AM, Rajan T, Lechleider RJ, Day RM. Transforming growth factor-beta1 effects on endothelial monolayer permeability involve focal adhesion kinase/Src. Am J Respir Cell Mol Biol. 2007; 37: 485-493.
    • (2007) Am J Respir Cell Mol Biol , vol.37 , pp. 485-493
    • Lee, Y.H.1    Kayyali, U.S.2    Sousa, A.M.3    Rajan, T.4    Lechleider, R.J.5    Day, R.M.6
  • 48
    • 82955163222 scopus 로고    scopus 로고
    • Heterotrimeric G proteins, focal adhesion kinase, and endothelial barrier function
    • Thennes T, Mehta D. Heterotrimeric G proteins, focal adhesion kinase, and endothelial barrier function. Microvasc Res. 2012; 83: 31-44.
    • (2012) Microvasc Res , vol.83 , pp. 31-44
    • Thennes, T.1    Mehta, D.2
  • 49
    • 82955198454 scopus 로고    scopus 로고
    • Role of FAK in S1P-regulated endothelial permeability
    • Belvitch P, Dudek SM. Role of FAK in S1P-regulated endothelial permeability. Microvasc Res. 2012; 83: 22-30.
    • (2012) Microvasc Res , vol.83 , pp. 22-30
    • Belvitch, P.1    Dudek, S.M.2
  • 50
    • 32344445820 scopus 로고    scopus 로고
    • CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: Cytoskeletonand integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner
    • Cohen-Hillel E, Yron I, Meshel T, Soria G, Attal H, Ben-Baruch A. CXCL8-induced FAK phosphorylation via CXCR1 and CXCR2: cytoskeletonand integrin-related mechanisms converge with FAK regulatory pathways in a receptor-specific manner. Cytokine. 2006; 3: 1-16.
    • (2006) Cytokine , vol.3 , pp. 1-16
    • Cohen-Hillel, E.1    Yron, I.2    Meshel, T.3    Soria, G.4    Attal, H.5    Ben-Baruch, A.6


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