Enhanced inflammation in aged mice following infection with Streptococcus pneumoniae is associated with decreased IL-10 and augmented chemokine production

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 308, Issue 6, 2015, Pages L539-L549

  Williams, Andrew E ^a   José, Ricardo J ^a   Brown, Jeremy S ^a   Chambers, Rachel C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Aging; Chemokine; Inflammation; Neutrophil; Pneumonia

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CXCL9 CHEMOKINE; EOTAXIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR; IL10 PROTEIN, MOUSE;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; INFLAMMATION; INNATE IMMUNITY; LUNG HOMOGENATE; LUNG LAVAGE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; YOUNG ADULT; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; IMMUNOLOGY; IMMUNOMODULATION; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY;

AGING; ANIMALS; CHEMOKINES; FEMALE; IMMUNOMODULATION; INTERLEUKIN-10; MICE; MICE, INBRED BALB C; NEUTROPHIL INFILTRATION; NEUTROPHILS; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE;

EID: 84937720120     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00141.2014     Document Type: Article

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