Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

Brain Pathology

Volumn 27, Issue 6, 2017, Pages 795-808

  Davies, Danielle S ^a   Ma, Jolande ^a   Jegathees, Thuvarahan ^a   Goldsbury, Claire ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

aging; Alzheimer's disease; confocal microscopy; dystrophic microglia; Iba1 protein; image analysis; imaging; immunofluorescence; microglia; morphology; post mortem human brain tissue; tau; tau protein

Indexed keywords

TAU PROTEIN;

AGED; AGING; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; CELL DENSITY; CELL LOSS; CELL STRUCTURE; CINGULATE GYRUS; CONTROLLED STUDY; DEGENERATIVE DISEASE; GRAY MATTER; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IN VITRO STUDY; INFERIOR TEMPORAL CORTEX; MACROPHAGE; MICROGLIA; NEUROFIBRILLARY TANGLE; NEUROPIL THREAD; QUANTITATIVE ANALYSIS; SENILE PLAQUE; BRAIN; CYTOLOGY; FEMALE; HIPPOCAMPUS; MALE; METABOLISM; NEOCORTEX; PATHOLOGY; PHYSIOLOGY;

AGING; ALZHEIMER DISEASE; AUTOPSY; BRAIN; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MICROGLIA; NEOCORTEX; TAU PROTEINS;

EID: 85008263113     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12456     Document Type: Article

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