High β-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice

American Journal of Physiology - Endocrinology and Metabolism

Volumn 296, Issue 6, 2009, Pages

  Masson, Elodie ^b   Koren, Shlomit ^b   Razik, Fathima ^b   Goldberg, Howard ^b   Kwan, Edwin P ^b   Sheu, Laura ^b   Gaisano, Herbert Y ^b   Fantus, I George ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b NONE

Author keywords

Apoptosis; Insulin secretion; Pancreatic cell; Thioredoxin interacting protein

Indexed keywords

GAMMA INTERFERON; INSULIN; INTERLEUKIN 1BETA; SMALL INTERFERING RNA; STREPTOZOCIN; THIOREDOXIN INTERACTING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; GENETIC TRANSFECTION; HYPERGLYCEMIA; INSULIN RELEASE; MALE; MASS; MOUSE; NONHUMAN; PANCREAS ISLET CELL MASS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STREPTOZOCIN DIABETES;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; CARRIER PROTEINS; CELL LINE; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; IN SITU NICK-END LABELING; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C3H; MICE, MUTANT STRAINS; RATS; STREPTOZOCIN; THIOREDOXINS;

EID: 66849119181     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90619.2008     Document Type: Article

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