Wnt3a upregulates brain-derived insulin by increasing NeuroD1 via Wnt/β-catenin signaling in the hypothalamus

Molecular Brain

Volumn 9, Issue 1, 2016, Pages

  Lee, Jaemeun ^a   Kim, Kyungchan ^a   Yu, Seong Woon ^a   Kim, Eun Kyoung ^a  

^a Daegu Gyeongbuk Institute of Science and Technology   (South Korea)

Author keywords

Brain derived insulin; Hypothalamus; NeuroD1; Wnt catenin signaling

Indexed keywords

BETA CATENIN; BRAIN DERIVED INSULIN; INSULIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3A PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; INS2 PROTEIN, MOUSE; NERVE PROTEIN; SMALL INTERFERING RNA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; GENE; GENE EXPRESSION; HYPOTHALAMUS; IN VITRO STUDY; INS2 GENE; INSULIN SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UPREGULATION; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; CELL LINE; DRUG EFFECTS; GENE SILENCING; LENTIVIRINAE; METABOLISM;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; GENE KNOCKDOWN TECHNIQUES; HYPOTHALAMUS; INSULIN; LENTIVIRUS; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; RNA, SMALL INTERFERING; UP-REGULATION; WNT SIGNALING PATHWAY; WNT3A PROTEIN;

EID: 85007591728     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/s13041-016-0207-5     Document Type: Article

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